1. Definitions and basic concepts -- 2. Have antibiotics and antibiotic resistance genes always been out there? -- 3. Human-related release of antibiotics into the environment -- 4. Spread of resistant organisms from human settlements into the environment -- 5. Impact of antibiotics and resistance in non-clinical settings.
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Antibiotic resistance in the environment: expert perspectives -- Antibiotic resistant bacteria in wildlife -- Genomic surveillance for One Health antimicrobial resistance: understanding human, animal, and environmental reservoirs and transmission -- Antibiotic resistance in pharmaceutical industry effluents and effluent-impacted environments -- Antibiotic resistance in municipal wastewater: A special focus on hospital effluents -- Control strategies to combat dissemination of antibiotic resistance in urban water systems -- Antibiotic resistance, sanitation and public health -- Antibiotic resistance and sanitation in India: current situation and future perspectives -- Mitigating antimicrobial resistance risks when using reclaimed municipal wastewater for agriculture -- Antibiotic resistance in soil -- Religious Mass Gathering (Hajj) and Antimicrobial Resistance: From Challenges to Opportunities -- Human movement and transmission of anti-microbial resistant bacteria.
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For an American in the 21st century, it is hard to imagine the world before antibiotics. At the beginning of the 20th century, as many as nine women out of every 1,000 who gave birth died, 40 percent from sepsis. In some cities as many as 30 percent of children died before their first birthday. One of every nine people who developed a serious skin infection died, even from something as simple as a scrape or an insect bite. Pneumonia killed 30 percent of those who contracted it; meningitis killed 70 percent. Ear infections caused deafness; sore throats were not infrequently followed by rheumati
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Characterization methods for microbial communities present in contaminated soils -- Antibiotic Resistance Genes as contaminants in Industrial Waste Water Treatment -- Bacteriophages: A strategy to combat antibiotic resistance in waste water treatment plants -- The emergence of Waste Water Treatment Plant as a leading source for dissemination of Antibiotic-Resistant Gene -- Increasing Prevalence of Antibiotic-resistant genes in industrial wastewater: impact on public health -- Antibiotic resistance genes as emerging contaminants in industrial waste water treatment -- Characterization and Dynamic Shift of Microbial Communities in wastewater treatment plant.
Characterization methods for microbial communities present in contaminated soils -- Antibiotic Resistance Genes as contaminants in Industrial Waste Water Treatment -- Bacteriophages: A strategy to combat antibiotic resistance in waste water treatment plants -- The emergence of Waste Water Treatment Plant as a leading source for dissemination of Antibiotic-Resistant Gene -- Increasing Prevalence of Antibiotic-resistant genes in industrial wastewater: impact on public health -- Antibiotic resistance genes as emerging contaminants in industrial waste water treatment -- Characterization and Dynamic Shift of Microbial Communities in wastewater treatment plant.
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"This book explores the role that environmental distribution of antimicrobial resistance genes and antibiotics plays in ecosystem and human health. The text features a multi-disciplinary framework that connects microbiology, environmental toxicology, and chemistry to assess human and ecological risk associated with exposure to antibiotics or antibiotic resistance genes as environmental contaminants. It also considers alternate uses and functions for antimicrobial compounds other than those intended for medicinal purposes in humans, animals, and fish. Recognizing the connectivity between overlapping complex systems, the book discusses the subject from the perspective of an ecosystem approach"--
This volume summarizes and updates information about antibiotics and antimicrobial resistance (AMR)/antibiotic resistant genes (ARG) production, including their entry routes in soil, air, water and sediment, their use in hospital and associated waste, global and temporal trends in use and spread of antibiotics, AMR and ARG. Antimicrobial/antibiotic resistance genes due to manure and agricultural waste applications, bioavailability, biomonitoring, and their Epidemiological, ecological and public health effects. The book addresses the antibiotic and AMR/ARG risk assessment and treatment technologies, for managing antibiotics and AMR/ARG impacted environments The book's expert contributions span 26 chapters, and offer a comprehensive framework for better understanding and analyzing the environmental and social impacts of antibiotics and AMR/ARGs. Readers will have access to recent and updated models regarding the interpretation of antibiotics and AMR/ARGs in environment and biomonitoring studies, and will learn about the management options require to appropriately mitigate environmental contaminants and pollution. The book will be of interest to students, teachers, researchers, policy makers and environmental organizations.
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This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the "bad bugs" are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike
For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.
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This work is a detailed survey of food safety issues today, from E-coli contamination in fruits and vegetables to food production practices that increase antibiotic resistance.