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In: Schriften zum Medizinstrafrecht Band 13
In: Nomos eLibrary
In: Strafrecht
Die Arbeit untersucht vor dem Hintergrund der gesetzlichen Neuregelung der Präimplantationsdiagnostik (PID) durch § 3a ESchG, ob die Regelung eine rechtssichere Handhabung der PID in Deutschland ermöglicht. Ein besonderer Fokus liegt dabei auf der Frage, ob das Ansinnen des Gesetzgebers, die PID lediglich in engen Grenzen zuzulassen, durch § 3a ESchG realisiert werden konnte. Die Arbeit hat darüber hinaus das Ziel, die Debatten um die PID mit Blick auf die sie betreffenden unterschiedlichen Disziplinen zu spiegeln: Der Ansatz ist trotz des rechtlichen Schwerpunkts daher ein interdisziplinärer. Die PID wird folglich nicht nur einfachgesetzlich, sondern auch aus medizinischer, ethischer und verfassungsrechtlicher Perspektive betrachtet. Bei der Untersuchung des Statuts des Embryos in vitro erfolgt dabei eine umfassende Analyse der Rechtswirklichkeit, wie sie in den gesetzlichen Regelungssystemen zum vorgeburtlichen Lebensschutz und in der Rechtsprechung des BVerfG Ausdruck findet.
In: Sustainable Construction Materials, S. xi-xi
In: Sustainable Food and Beverage Industries, S. 281-284
In: Analysis of Poverty Data by Small Area Estimation, S. 427-430
This title is endorsed by Cambridge Assessment International Education to support the full syllabus for examination from 2020. Reinforce learning and deepen understanding of the key concepts covered in the latest syllabus; an ideal course companion or homework book for use throughout the course. - Develop and strengthen skills and knowledge with a wealth of additional exercises that perfectly supplement the Student's Book. - Build confidence with extra practice for each lesson to ensure that a topic is thoroughly understood before moving on. - Build a strong understanding of the main events of the course and the confidence to know how to use this knowledge. - Keep track of students' work with ready-to-go write-in exercises. - Save time with all answers available in the Online Teacher's Guide
Semaphorin 3A (Sema3A) is a cell-secreted protein that participates in the axonal guidance pathways. Sema3A acts as a canonical repulsive axon guidance molecule, inhibiting CNS regenerative axonal growth and propagation. Therefore, interfering with Sema3A signaling is proposed as a therapeutic target for achieving functional recovery after CNS injuries. It has been shown that Sema3A adheres to the proteoglycan component of the extracellular matrix (ECM) and selectively binds to heparin and chondroitin sulfate-E (CS-E) glycosaminoglycans (GAGs). We hypothesize that the biologically relevant interaction between Sema3A and GAGs takes place at Sema3A C-terminal polybasic region (SCT). The aims of this study were to characterize the interaction of the whole Sema3A C-terminal polybasic region (Sema3A 725–771) with GAGs and to investigate the disruption of this interaction by small molecules. Recombinant Sema3A basic domain was produced and we used a combination of biophysical techniques (NMR, SPR, and heparin affinity chromatography) to gain insight into the interaction of the Sema3A C-terminal domain with GAGs. The results demonstrate that SCT is an intrinsically disordered region, which confirms that SCT binds to GAGs and helps to identify the specific residues involved in the interaction. NMR studies, supported by molecular dynamics simulations, show that a new peptoid molecule (CSIC02) may disrupt the interaction between SCT and heparin. Our structural study paves the way toward the design of new molecules targeting these protein–GAG interactions with potential therapeutic applications. ; This work was funded by the European Union Seventh Framework Programme (FP7/2007–2013) under Project VISION, grant No. 304884, the Spanish Ministry of Science and Innovation/Spanish Research Agency (MCI/AEI/FEDER, RTI2018–096182-B-I00) and AGAUR (2017 SGR 208). ; Peer reviewed
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The author, writer and filmmaker Neil Hollander has been having a successful career for more than three decades. He's been author of several books for kids and more books that serve as a manuals for surviving on open sea. With his latest books Hollander has been advocating for world peace and bringing closer to the public the horrific life of people living under military regime in Burma. He is also active as a public speaker covering these and similar subjects. As a filmmaker Hollander started his career back in 70's when together with Harald Mertes went on a voyage around the Ocean on a sailing boat, Spending three years on this trip he visited many places and learned many things about life on sea. Later he documented these finding in his book, which he also used as a screenplay for his awarded documentary film The Last Sailors: The Final Days of Working Sail. The film is hosted by Orson Welles who in this classic documentary film tells the story of the men who, with their ancient craft, still harness the wind and the sea for their livelihood. The film includes stories from people living all over the world, including countries like Egypt, Bangladesh, Indonesia, Brazil, Costa Rica and other places. Hollander is artist that is best known for his exhibitions hosted in collaboration with some world-recognized museums and art schools. In his career he has worked with the Smithsonian, the Deutsches Museum and the Jim Thompson House in Bangkok. Lately his project are publicly visible at his portfolio at Rhode Island School of Design (RISD). Projects worth mentioning as one of the best in his portfolio include Hollander's Nobel Voices, Neil Hollander Burma A Human Tragedy, Birds of Passage, H for Hunger, to name a few.
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In: Wirtschafts- und Steuerrecht Band 29
Der Erfolg von Restrukturierungen hängt regelmäßig entscheidend von der steuerlichen Behandlung von durch Sanierungsmaßnahmen ausgelösten Gewinnen ab. Die Anwendung der zu diesem Zweck geschaffenen Steuerbefreiung des 3a EStG ist jedoch aufgrund zahlreicher Auslegungsfragen konfliktträchtig. Die Arbeit zeigt daher umfassend die bekannten und neu entstanden Probleme hinsichtlich ihres Anwendungsbereichs, der Voraussetzungen und Rechtsfolgen auf, entwickelt auf Basis der einschlägigen Literatur praxisgerechte Lösungen und bietet so eine verlässliche Hilfe für die Sanierungspraxis.In einem zweiten Schwerpunkt widmet sich die Arbeit einer Prüfung der Vereinbarkeit von 3a EStG mit dem allgemeinen Gleichheitssatz des Art. 3 Abs. 1 GG
In: What Does Suburbia Vote for?, S. 324-324
In: Wirtschafts- und Steuerrecht Band 29
In: Nomos eLibrary
In: Öffentliches Recht
Der Erfolg von Restrukturierungen hängt regelmäßig entscheidend von der steuerlichen Behandlung von durch Sanierungsmaßnahmen ausgelösten Gewinnen ab. Die Anwendung der zu diesem Zweck geschaffenen Steuerbefreiung des § 3a EStG ist jedoch aufgrund zahlreicher Auslegungsfragen konfliktträchtig. Die Arbeit zeigt daher umfassend die bekannten und neu entstanden Probleme hinsichtlich ihres Anwendungsbereichs, der Voraussetzungen und Rechtsfolgen auf, entwickelt auf Basis der einschlägigen Literatur praxisgerechte Lösungen und bietet so eine verlässliche Hilfe für die Sanierungspraxis. In einem zweiten Schwerpunkt widmet sich die Arbeit einer Prüfung der Vereinbarkeit von § 3a EStG mit dem allgemeinen Gleichheitssatz des Art. 3 Abs. 1 GG.
In: http://hdl.handle.net/2445/171032
Treballs Finals del Màster d'Advocacia, Facultat de Dret, Universitat de Barcelona, Curs: 2019-2020, Tutor: Dos Santos V. Factor, Javier
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73 92 52 1 ; S ; This is the author's version of a work that was accepted for publication in Information Processing and Management. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Information Processing and Management 52 (2016) 73–92. DOI 10.1016/j.ipm.2015.06.003. [EN] In this paper, we investigate the impact of emotions on author profiling, concretely identifying age and gender. Firstly, we propose the EmoGraph method for modelling the way people use the language to express themselves on the basis of an emotion-labelled graph. We apply this representation model for identifying gender and age in the Spanish partition of the PAN-AP-13 corpus, obtaining comparable results to the best performing systems of the PAN Lab of CLEF. © 2015 Elsevier B.V. All rights reserved. The work of the first author was partially funded by Autoritas Consulting SA and by Spanish Ministry of Economics under grant ECOPORTUNITY IPT-2012-1220-430000. The work of the second author was carried out in the framework of the WIQ-EI IRSES project (Grant No. 269180) within the FP 7 Marie Curie, the DIANA APPLICATIONS: Finding Hidden Knowledge in Texts: Applications (TIN2012-38603-C02-01) project and the VLC/CAMPUS Microcluster on Multimodal Interaction in Intelligent Systems. A special mention to Maria Dolores Rangel Pardo for her linguistic contribution to this investigation. Rangel-Pardo, FM.; Rosso, P. (2016). On the Impact of Emotions on Author Profiling. Information Processing and Management. 52(1):73-92. https://doi.org/10.1016/j.ipm.2015.06.003
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