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In: Sustainable Construction Materials, S. xi-xi
Author Notes
In: Sustainable Food and Beverage Industries, S. 281-284
Author Index
In: Analysis of Poverty Data by Small Area Estimation, S. 427-430
Semaphorin 3A—Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration
Semaphorin 3A (Sema3A) is a cell-secreted protein that participates in the axonal guidance pathways. Sema3A acts as a canonical repulsive axon guidance molecule, inhibiting CNS regenerative axonal growth and propagation. Therefore, interfering with Sema3A signaling is proposed as a therapeutic target for achieving functional recovery after CNS injuries. It has been shown that Sema3A adheres to the proteoglycan component of the extracellular matrix (ECM) and selectively binds to heparin and chondroitin sulfate-E (CS-E) glycosaminoglycans (GAGs). We hypothesize that the biologically relevant interaction between Sema3A and GAGs takes place at Sema3A C-terminal polybasic region (SCT). The aims of this study were to characterize the interaction of the whole Sema3A C-terminal polybasic region (Sema3A 725–771) with GAGs and to investigate the disruption of this interaction by small molecules. Recombinant Sema3A basic domain was produced and we used a combination of biophysical techniques (NMR, SPR, and heparin affinity chromatography) to gain insight into the interaction of the Sema3A C-terminal domain with GAGs. The results demonstrate that SCT is an intrinsically disordered region, which confirms that SCT binds to GAGs and helps to identify the specific residues involved in the interaction. NMR studies, supported by molecular dynamics simulations, show that a new peptoid molecule (CSIC02) may disrupt the interaction between SCT and heparin. Our structural study paves the way toward the design of new molecules targeting these protein–GAG interactions with potential therapeutic applications. ; This work was funded by the European Union Seventh Framework Programme (FP7/2007–2013) under Project VISION, grant No. 304884, the Spanish Ministry of Science and Innovation/Spanish Research Agency (MCI/AEI/FEDER, RTI2018–096182-B-I00) and AGAUR (2017 SGR 208). ; Peer reviewed
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Neil Hollander Author
The author, writer and filmmaker Neil Hollander has been having a successful career for more than three decades. He's been author of several books for kids and more books that serve as a manuals for surviving on open sea. With his latest books Hollander has been advocating for world peace and bringing closer to the public the horrific life of people living under military regime in Burma. He is also active as a public speaker covering these and similar subjects. As a filmmaker Hollander started his career back in 70's when together with Harald Mertes went on a voyage around the Ocean on a sailing boat, Spending three years on this trip he visited many places and learned many things about life on sea. Later he documented these finding in his book, which he also used as a screenplay for his awarded documentary film The Last Sailors: The Final Days of Working Sail. The film is hosted by Orson Welles who in this classic documentary film tells the story of the men who, with their ancient craft, still harness the wind and the sea for their livelihood. The film includes stories from people living all over the world, including countries like Egypt, Bangladesh, Indonesia, Brazil, Costa Rica and other places. Hollander is artist that is best known for his exhibitions hosted in collaboration with some world-recognized museums and art schools. In his career he has worked with the Smithsonian, the Deutsches Museum and the Jim Thompson House in Bangkok. Lately his project are publicly visible at his portfolio at Rhode Island School of Design (RISD). Projects worth mentioning as one of the best in his portfolio include Hollander's Nobel Voices, Neil Hollander Burma A Human Tragedy, Birds of Passage, H for Hunger, to name a few.
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Short biography of the author
In: What Does Suburbia Vote for?, S. 324-324
Caso de derechos de la personalidad. 3A (parte demandante)
In: http://hdl.handle.net/2445/171032
Treballs Finals del Màster d'Advocacia, Facultat de Dret, Universitat de Barcelona, Curs: 2019-2020, Tutor: Dos Santos V. Factor, Javier
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On the Impact of Emotions on Author Profiling
73 92 52 1 ; S ; This is the author's version of a work that was accepted for publication in Information Processing and Management. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Information Processing and Management 52 (2016) 73–92. DOI 10.1016/j.ipm.2015.06.003. [EN] In this paper, we investigate the impact of emotions on author profiling, concretely identifying age and gender. Firstly, we propose the EmoGraph method for modelling the way people use the language to express themselves on the basis of an emotion-labelled graph. We apply this representation model for identifying gender and age in the Spanish partition of the PAN-AP-13 corpus, obtaining comparable results to the best performing systems of the PAN Lab of CLEF. © 2015 Elsevier B.V. All rights reserved. The work of the first author was partially funded by Autoritas Consulting SA and by Spanish Ministry of Economics under grant ECOPORTUNITY IPT-2012-1220-430000. The work of the second author was carried out in the framework of the WIQ-EI IRSES project (Grant No. 269180) within the FP 7 Marie Curie, the DIANA APPLICATIONS: Finding Hidden Knowledge in Texts: Applications (TIN2012-38603-C02-01) project and the VLC/CAMPUS Microcluster on Multimodal Interaction in Intelligent Systems. A special mention to Maria Dolores Rangel Pardo for her linguistic contribution to this investigation. Rangel-Pardo, FM.; Rosso, P. (2016). On the Impact of Emotions on Author Profiling. Information Processing and Management. 52(1):73-92. https://doi.org/10.1016/j.ipm.2015.06.003
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ROHINTON MISTRY AS A DIASPORIC AUTHOR
The writings of the Indian Diaspora have received a great deal of attention and critical acclaim throughout the world. Rohinton Mistry is a well renowned author in the contemporary commonwealth literature and occupies a significant place among the writers of Indian Diaspora. Even though he is settled in Canada; it is his upbringing in Mumbai that reflects in all his writings. The distinct Mumbai culture, particularly the Parsee way of life, the people of the city and even the politics of India are major themes in his novels. Rohinton Mistry as a writer of Diaspora has carved a niche for himself. His works such as: "Tales from Firozsha Baag", "Such A Long Journey", "A Fine Balance" and "Family Matters";mark a new kind of writing, resulting from a fragmented, splintered world. As a Diasporic Parsi writer, very sensitively he has recalled his community's journey through time and history with a sense of loss and nostalgia. His books portray diverse facets of Indian socioeconomic life; as well as Parsi Zoroastrian life, customs, and religion. Many of his writings are markedly "Indo-nostalgic". Rohinton Mistry through his Diasporic discourse has well depicted his ancestral background, his community's engaged situation in a metropolis like Bombay and his deep attachment with and nostalgia for a world gone by. In this paper an attempt has been made to delineate diasporic discourse in the works of Rohinton Mistry. Although he is obsessed with the colonial and postcolonial experiences in India, we can find some traces of Canada in his literature. His characters dream of being integrated into, and accepted by, Canadian society on the one hand and on the other hand, these same characters are torn by an insatiable desire to be true to their native culture; to honor and cherish their own, distinct cultural identity.
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ROHINTON MISTRY AS A DIASPORIC AUTHOR
The writings of the Indian Diaspora have received a great deal of attention and critical acclaim throughout the world. Rohinton Mistry is a well renowned author in the contemporary commonwealth literature and occupies a significant place among the writers of Indian Diaspora. Even though he is settled in Canada; it is his upbringing in Mumbai that reflects in all his writings. The distinct Mumbai culture, particularly the Parsee way of life, the people of the city and even the politics of India are major themes in his novels. Rohinton Mistry as a writer of Diaspora has carved a niche for himself. His works such as: "Tales from Firozsha Baag", "Such A Long Journey", "A Fine Balance" and "Family Matters"; mark a new kind of writing, resulting from a fragmented, splintered world. As a Diasporic Parsi writer, very sensitively he has recalled his community's journey through time and history with a sense of loss and nostalgia. His books portray diverse facets of Indian socioeconomic life; as well as Parsi Zoroastrian life, customs, and religion. Many of his writings are markedly "Indo-nostalgic". Rohinton Mistry through his Diasporic discourse has well depicted his ancestral background, his community's engaged situation in a metropolis like Bombay and his deep attachment with and nostalgia for a world gone by. In this paper an attempt has been made to delineate diasporic discourse in the works of Rohinton Mistry. Although he is obsessed with the colonial and postcolonial experiences in India, we can find some traces of Canada in his literature. His characters dream of being integrated into, and accepted by, Canadian society on the one hand and on the other hand, these same characters are torn by an insatiable desire to be true to their native culture; to honor and cherish their own, distinct cultural identity.Keywords: Diaspora, Cultural identity, Contemporary Canadian literature, Parsi.
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The Arc of Rhetoric and the Leader as Author
In: Leadership and the Labour Party, S. 81-116
From Author–God to Textual Communion
In: Greek Fragments in Postmodern Frames, S. 103-130
Novel Fatty Acid Chain-Shortening by Fungal Peroxygenases Yielding 2C-Shorter Dicarboxylic Acids
10 páginas.- 4 figuras.- referencias.-Data Availability Statement: All data underlying this article are available in the main publication and in its Supplementary Materials online. ; Unspecific peroxygenases (UPOs), the extracellular enzymes capable of oxygenating a potpourri of aliphatic and aromatic substrates with a peroxide as co-substrate, come out with a new reaction: carbon-chain shortening during the conversion of fatty acids with the well-known UPOs from Coprinopsis cinerea (rCciUPO) and Cyclocybe (Agrocybe) aegerita (AaeUPO). Although a pathway (Cα-oxidation) for shortening the hydrocarbon chain of saturated fatty acids has already been reported for the UPO from Marasmius rotula (MroUPO), it turned out that rCciUPO and AaeUPO shorten the chain length of both saturated and unsaturated fatty acids in a different way. Thus, the reaction sequence does not necessarily start at the Cα-carbon (adjacent to the carboxyl group), as in the case of MroUPO, but proceeds through the subterminal (ω-1 and ω-2) carbons of the chain via several oxygenations. This new type of shortening leads to the formation of a dicarboxylic fatty acid reduced in size by two carbon atoms in the first step, which can subsequently be further shortened, carbon by carbon, by the UPO Cα-oxidation mechanism. View Full-Text ; This research was funded by BioBased Industries Joint Undertaking under the European Union's Horizon 2020 Research and Innovation Programme, grant number 792063 (SusBind project; https://susbind.eu; to A.G., Á.T.M. and M.H.), the PID2020-118968RB-100 project by the Spanish MCIN/AEI/ 10.13039/501100011033 to A.G., and the CSIC projects PIE-202040E185 (to A.G.) and PIE-202120E019 (to Á.T.M.). ; Peer reviewed
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Michael Lewis: Journalist and Bestselling Author
Michael Lewis is a New York Times bestselling author who has written more than a dozen books on subjects ranging from politics to Wall Street. His recently released book, "Fifth Risk," explores mismanagement in federal government. His other books include "The Big Short," "Moneyball" and "The Blind Side" - all of which were made into movies. Another, "Liar's Poker," was based partly on his experience as a bond salesman at Salomon Brothers. Lewis is a sharp observer of politics, finance and the evolution of American culture, combining keen insight with a sharp sense of humor. He is a columnist for Bloomberg News and a contributing writer to Vanity Fair. His articles have also appeared in The New York Times Magazine, The New Yorker and Sports Illustrated.
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