Suchergebnisse

The Baltic Sea ecosystem is subject to a wide array of societal pressures and associated environmental risks (e.g. eutrophication, oil discharges, chemical pollution, overfishing and invasive alien species). Despite several years of substantial efforts by state and non-state actors, it is still highly unlikely that the regionally agreed environmental objectives of reaching "good environmental status" by 2021 in the HELCOM BSAP (Baltic Sea Action Plan) and by 2020 in the EU Marine Strategy Framework Directive (MSFD) will be met. This chapter identifies key research topics, as well as presents analytical perspectives for analysing the gap between knowledge and action in Baltic Sea environmental governance. It does so by outlining important trends and key challenges associated with Baltic Sea environmental governance, as well as by summarising the scope and results of individual chapters of this interdisciplinary volume. The analysis reveals the development of increasingly complex governance arrangements and the ongoing implementation of the holistic Ecosystem Approach to Management, as two general trends that together contribute to three key challenges associated with (1) regional and cross - sectoral coordination and collaboration, (2) coping with complexity and uncertainty in science-policy interactions and (3) developing communication and knowledge sharing among stakeholder groups. Furthermore, to facilitate analysis of environmental governance opportunities and obstacles both within and across specific environmental issues, this chapter reviews the scientific literature to pinpoint key research issues and questions linked to the identified governance challenges.

Abstract
Potentially harmful compounds including pharmaceuticals are commonly found in marine waters and sediments. Amongst those, antibiotics and their metabolites are detected worldwide in various abiotic (at concentrations as high as µg/L) and biotic matrices at ng/gram of tissue, posing a risk to non-target species exposed to them such as blue mussels. Amongst those, oxytetracycline (OTC) belongs to the most detected antibiotics in the marine environment. In this work, we concentrated on studying the potential induction of oxidative stress, activation of cellular detoxification processes (including Phase I and Phase II xenobiotic biotransformation enzymes) and multixenobiotic resistance pumps (Phase III) as well as changes in the aromatisation efficiency in Mytilus trossulus exposed to 100 μg/L OTC. Our results show that 100 µg/L OTC concentration did not provoke cellular oxidative stress and did not affect the expression of genes involved in detoxification processes in our model. Moreover, no effect of OTC on aromatisation efficiency was found. Instead, phenoloxidase activity measured in haemolymph was significantly higher in OTC exposed mussels than in those from the control (30.95 ± 3.33 U/L and 17.95 ± 2.75 U/L, respectively). OTC exposed mussels were also characterised by a tissue-dependant activation of major vault protein (MVP) gene expression (1.5 times higher in gills and 2.4 times higher in the digestive system) and a decreased expression of the nuclear factor kappa B-a (NF-κB) gene (3.4 times lower in the digestive system) when compared to those from the control. Additionally, an elevated number of regressive changes and inflammatory responses in tissues such as gills, digestive system and mantle (gonads) was observed underlining the worsening of bivalves' general health. Therefore, instead of a free-radical effect of OTC, we for the first time describe the occurrence of typical changes resulting from antibiotic therapy in non-target organisms like M. trossulus exposed to antibiotics such as OTC.