The Melbourne Diabetes Prevention Study (MDPS): study protocol for a randomized controlled trial

Abstract

Worldwide, type 2 diabetes (T2DM) prevalence has more than doubled over two decades. In Australia, diabetes is the second highest contributor to the burden of disease. Lifestyle modification programs comprising diet changes, weight loss and moderate physical activity, have been proven to reduce the incidence of T2DM in high risk individuals. As part of the Council of Australia Governments, the State of Victoria committed to develop and support the diabetes prevention program 'Life! Taking action on diabetes' (Life!) which has direct lineage from effective clinical and implementation trials from Finland and Australia. The Melbourne Diabetes Prevention Study (MDPS) has been set up to evaluate the effectiveness and cost-effectiveness of a specific version of the Life! program. ; This study was funded by the National Health and Medical Research Council, grant number: 533819. We would like to acknowledge the Department of Health Victoria, which funded Life!, and Prof Greg Johnson and Dr Amy Timoshanko from Diabetes Australia Victoria