Open Access BASE

The Malawi NCD BRITE Consortium: Building Research Capacity, Implementation, and Translation Expertise for Noncommunicable Diseases

van Oosterhout, Joep J.; Department of Medicine, University of Malawi, College of Medicine, Blantyre; Dignitas International, Zomba; Hosseinipour, Mina; University of North Carolina-Project Malawi, Lilongwe; Muula, Adamson S.; Department of Public Health, University of Malawi, College of Medicine, Blantyre; Amberbir, Alemayehu; Dignitas International, Zomba; Wroe, Emily; Department of Public Health, University of Malawi, College of Medicine, Blantyre; Berman, Josh; Dignitas International, Zomba; Maliwichi-Nyirenda, Cecilia; Research Support Center, University of Malawi, College of Medicine, Mahatma Gandhi Road, Blantyre; Mwapasa, Victor; Department of Public Health, University of Malawi, College of Medicine, Blantyre; Crampin, Amelia; Malawi Epidemiology and Intervention Research Unit, Lilongwe; Makwero, Martha; Department of Family Medicine, University of Malawi, College of Medicine, Blantyre; Singogo, Emmanuel; Dignitas International, Zomba; Gopal, Satish; University of North Carolina-Project Malawi, Lilongwe; Baker, Ulrika; Department of Family Medicine, University of Malawi, College of Medicine, Blantyre; Phiri, Samuel; Research Support Center, University of Malawi, College of Medicine, Mahatma Gandhi Road, Blantyre; Gordon, Stephen B.; Malawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre; Tobe, Sheldon; Department of Medicine, Division of Nephrology, Sunnybrook Health Sciences Centre, University of Toronto and the Northern Ontario School of Medicine, Toronto, Ontario; Chiwanda, Jonathan; Department of Non-communicable Diseases, Ministry of Health, Lilongwe; Masiye, Jones; Department of Non-communicable Diseases, Ministry of Health, Lilongwe; Parks, John; Department of Family Medicine, University of Malawi, College of Medicine, Blantyre; Mitambo, Collins; Department of HIV-AIDS, Ministry of Health, Lilongwe; Gondwe, Austrida; Department of Medicine, University of Malawi, College of Medicine, Blantyre; Dullie, Luckson; Research Support Center, University of Malawi, College of Medicine, Mahatma Gandhi Road, Blantyre; Newsome, Brad; National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD; Nyirenda, Moffat; Research Support Center, University of Malawi, College of Medicine, Mahatma Gandhi Road, Blantyre

Abstract

Africa is experiencing an increasing prevalence of noncommunicable diseases (NCD). However, few reliable data are available on their true burden, main risk factors, and economic impact that are needed to inform implementation of evidence-based interventions in the local context. In Malawi, a number of initiatives have begun addressing the NCD challenge, which have often utilized existing infectious disease infrastructure. It will be crucial to carefully leverage these synergies to maximize their impact. NCD-BRITE (Building Research Capacity, Implementation, and Translation Expertise) is a transdisciplinary consortium that brings together key research institutions, the Ministry of Health, and other stakeholders to build longterm, sustainable, NCD-focused implementation research capacity. Led by University of Malawi—College of Medicine, University of North Carolina, and Dignitas International, NCD-BRITE's specific aims are to conduct detailed assessments of the burden and risk factors of common NCD; assess the research infrastructure needed to inform, implement, and evaluate NCD interventions; create a national implementation research agenda for priority NCD; and develop NCD-focused implementation research capacity through short courses, mentored research awards, and an internship placement program. The capacity-building activities are purposely designed around the University of Malawi—College of Medicine and Ministry of Health to ensure sustainability. The NCD BRITE Consortium was launched in February 2018. In year 1, we have developed NCD-focused implementation research capacity. Needs assessments will follow in years 2 and 3. Finally, in year 4, the generated research capacity, together with findings from the needs assessments, will be used to create a national, actionable, implementation research agenda for NCD prioritized in this consortium, namely cardiovascular disease, diabetes mellitus, and asthma and chronic obstructive pulmonary disease.HighlightsNCD-BRITE is a transdisciplinary consortium that brings together key research institutions, the MOH, and other stakeholders to build long-term, sustainable, NCD-focused implementation research capacity.NCD-BRITE's specific aims are to conduct detailed assessments of the burden and risk factors of common NCD (hypertension, diabetes mellitus, COPD and asthma); assess the research infrastructure needed to inform, implement, and evaluate NCD interventions; create a national implementation research agenda for priority NCD; and develop NCD-focused implementation research capacity through short courses, mentored research awards, and an internship placement program.The capacity-building activities are purposely designed around the College of Medicine and the Government of Malawi MOH to ensure sustainability.It was initiated in 2017 and has successfully completed 2 years of operation.

Sprachen

Englisch

Verlag

Ubiquity Press

DOI

10.1016/j.gheart.2019.05.004

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