Open Access BASE2012

Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs

Bousquet, J; Schuenemann, H. J; Samolinski, B; Demoly, P; Baena-Cagnani, Carlos E; Bachert, C; Bonini, S; Boulet, L. P; Bousquet, P. J; Brozek, J. L; Canonica, G. W; Casale, T. B; Cruz, A. A; Fokkens, W. J; Fonseca, J. A; van Wijk, R. Gerth; Grouse, L; Haahtela, T; Khaltaev, N; Kuna, P; Lockey, R. F; Carlsen, K. C. Lodrup; Mullol, J; Naclerio, R; O'Hehir, R. E; Ohta, K; Palkonen, S; Papadopoulos, N. G; Passalacqua, G; Pawankar, R; Price, D; Ryan, D; Simons, F. E. R; Togias, A; Williams, D; Yorgancioglu, A; Yusuf, O. M; Aberer, W; Adachi, M; Agache, I; Ait-Khaled, N; Akdis, C. A; Andrianarisoa, A; Annesi-Maesano, I; Ansotegui, I. J; Baiardini, I; Bateman, E. D; Bedbrook, A; Beghe, B; Beji, M; Bel, E. H; Ben Kheder, A; Bennoor, K. S; Bergmann, K. C; Berrissoul, F; Bieber, T; Jensen, C. Bindslev; Blaiss, M. S; Boner, A. L; Bouchard, J; Braido, F; Brightling, C. E; Bush, A; Caballero, F; Calderon, M. A; Calvo, M. A; Camargos, P. A. M; Caraballo, L. R; Carlsen, K. H; Carr, W; Cepeda, A. M; Cesario, A; Chavannes, N. H; Chen, Y. Z; Chiriac, A. M; Chivato Perez, T; Chkhartishvili, E; Ciprandi, G; Costa, D. J; Cox, L; Custovic, A; Dahl, R; Darsow, U; De Blay, F; Deleanu, D; Denburg, J. A; Devillier, P; Didi, T; Dokic, D; Dolen, W. K; Douagui, H; Dubakiene, R; Durham, S. R; Dykewicz, M. S; El-Gamal, Y; El-Meziane, A; Emuzyte, R; Fiocchi, A; Fletcher, M; Fukuda, T; Gamkrelidze, A; Gereda, J. E; Gonzalez Diaz, S; Gotua, M; Guzman, M. A; Hellings, P. W; Hellquist-Dahl, B; Horak, F; Hourihane, J. O'B; Howarth, P; Humbert, M; Ivancevich, J. C; Jackson, C; Just, J; Kalayci, O; Kaliner, M. A; Kalyoncu, A. F; Keil, T; Keith, P. K; Khayat, G; Kim, Y. Y; N'Goran, B. Koffi; Koppelman, G. H; Kowalski, M. L; Kull, I; Kvedariene, V; Larenas-Linnemann, D; Le, L. T; Lemiere, C; Li, J; Lieberman, P; Lipworth, B; Mahboub, B; Makela, M. J; Martin, F; Marshall, G. D; Martinez, F. D; Masjedi, M. R; Maurer, M; Mavale-Manuel, S; Mazon, A; Melen, E; Meltzer, E. O; Mendez, N. H; Merk, H; Mihaltan, F; Mohammad, Y; Morais-Almeida, M; Muraro, A; Nafti, S; Namazova-Baranova, L; Nekam, K; Neou, A; Niggemann, B; Nizankowska-Mogilnicka, E; Nyembue, T. D; Okamoto, Y; Okubo, K; Orru, M. P; Ouedraogo, S; Ozdemir, C; Panzner, P; Pali-Schoell, I; Park, H. S; Pigearias, B; Pohl, W; Popov, T. A; Postma, D. S; Potter, P; Rabe, K. F; Ratomaharo, J; Reitamo, S; Ring, J; Roberts, R; Rogala, B; Romano, A; Rodriguez, M. Roman; Rosado-Pinto, J; Rosenwasser, L; Rottem, M; Sanchez-Borges, M; Scadding, G. K; Schmid-Grendelmeier, P; Sheikh, A; Sisul, J. C; Sole, D; Sooronbaev, T; Spicak, V; Spranger, O; Stein, R. T; Stoloff, S. W; Sunyer, J; Szczeklik, A; Todo-Bom, A; Toskala, E; Tremblay, Y; Valenta, R; Valero, A. L; Valeyre, D; Valiulis, A; Valovirta, E; Van Cauwenberge, P; Vandenplas, O; van weel, C; Vichyanond, P; Viegi, G; Wang, D. Y; Wickman, M; Woehrl, S; Wright, J; Yawn, B. P; Yiallouros, P. K; Zar, H. J; Zernotti, M. E; Zhong, N; Zidarn, M; Zuberbier, T; World Hlth Org Collaborating Ctr

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Abstract

Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified ARas mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. in its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIAWorld Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children. (J Allergy Clin Immunol 2012;130:1049-62.) ; Stallergenes ; ALK-Abello ; European Academy of Allergy and Clinical Immunology (EAACI) ; MSD ; Novartis ; Nycomed/Takeda ; PHADIA/Thermo Fischer ; 3M ; AstraZeneca ; GlaxoSmithKline ; Merck Frosst ; Altair ; Amgen ; Asmacure ; Boehringer-Ingelheim ; Genentech ; Pharmaxis ; Schering ; Wyeth ; Ache ; Brazilian Research Council ; Fundacao de Amparo a Pesquisa da Bahia ; Fundacao Ciencia e Tecnologia ; Sociedade Portuguesa de Alergologia e Immunologia Clinica ; Abdi Ibrahim ; OrionPharma ; Nasonebs ; Merck ; McNeal ; Chiesi ; Nycomed ; Air Liquid Healthcare ; Mundipharma ; Almirall ; Kyorin ; Teva ; UK National Health Service ; Aerocrine ; AKL Ltd ; PREDICTA ; Swiss National Science Foundation ; MeDALL ; Global Allergy and Asthma European Network (GA 2LEN) ; Christine Kuthe Center for Allergy Research and Education ; Faes Farma ; Bial ; Johnson Johnson ; Sanofi ; HAD treasurer ; Innovative Medicine Initiative (EU) ; Helse Sor-Ost RHF (Southern and Eastern Norway Regional Health Authority) ; MEDA ; Alcon ; ISTA ; Thermo-Fisher ; Airsonett ; Medical Research Council ; Moulton Charitable Trust ; AB Science ; Canadian Institutes for Health Research ; AllerGen NCE ; Merck/Schering-Plough ; Circassia ; University Hospital ; Medical School of Universidad Autonoma de Nuevo Leon, Mexico ; Children's Research Foundation (Ireland) ; Danone ; Food Standards Agency (United Kingdom) ; European Union (EU) ; DTG ; Netherlands Asthma Foundation ; Merck-Sharp-Dohme, Mexico ; Allerquim Mexico ; Abbott ; Apotex ; HRA ; MedImmune ; Schering-Plough ; Proctor Gamble ; Sunovion (Sepracor) ; Phadia ; Servier ; CSC JohnsonJohnson ; Oxygen Plus ; New Medics ; European Respiratory Society ; Societe de Pneumologie de Langue Francaise Asthma ; Ministry of Health, Welfare, and Labor ; Altana ; Takeda ; UCB ; Uriach advisory board ; NAPP ; Royal College of GPs Clinical Champion in Allergy ; Agency for Healthcare Research and Quality (AHRQ) ; AnseII ; Bayer Schering ; OST ; Fujisawa ; IHAL ; Henkel ; Kryolan ; Leti ; MSO ; Procter and Gamble ; Sanofi-Aventis ; Scientific Advisory Board for the German Society for Allergy and Clinical Immunology ; German Federal Ministry of Consumer Protection ; European Centre for Allergy Research Foundation (ECARF) ; Hop Arnaud Villeneuve, Dept Resp Dis, Univ Hosp, Montpellier, France ; INSERM, U1018, CESP Ctr Res Epidemiol & Populat Hlth, Resp & Environm Epidemiol Team, Villejuif, France ; McMaster Univ, Dept Clin Epidemiol & Biostat & Med, Hamilton, ON, Canada ; Med Univ Warsaw, Dept Prevent Environm Hazards & Allergol, Warsaw, Poland ; Univ Hosp Montpellier, Hop Arnaud Villeneuve, INSERM, U657, Montpellier, France ; Catholic Univ, Fac Med, Res Ctr Resp Med CIMER, Cordoba, Argentina ; Univ Genoa, Sch Specializat, Genoa, Italy ; Univ Ghent, Dept Otorhinolaryngol, Upper Airways Res Lab, B-9000 Ghent, Belgium ; CNR, Inst Translat Pharmacol, Rome, Italy ; Univ Naples 2, Naples, Italy ; Univ Laval, Inst Univ Cardiol & Pneumol Quebec, Quebec City, PQ, Canada ; Univ Genoa, Dept Internal Med, DIMI, I-16126 Genoa, Italy ; Creighton Univ, Dept Med, Div Allergy & Immunol, Omaha, NE 68178 USA ; Univ Fed Bahia, ProAR Nucleo Excelencia Asma, Salvador, BA, Brazil ; CNPq, Salvador, BA, Brazil ; Univ Amsterdam, Dept Otorhinolaryngol, NL-1012 WX Amsterdam, Netherlands ; Univ Amsterdam, Acad Med Ctr, Dept Otorhinolaryngol, NL-1105 AZ Amsterdam, Netherlands ; Univ Porto, Sch Med, Dept Hlth Informat & Decis Sci, P-4100 Oporto, Portugal ; Univ Porto, Sch Med, CINTESIS, P-4100 Oporto, Portugal ; Hosp S Joao & Inst, Dept Allergy, Oporto, Portugal ; Hosp CUF Porto, Oporto, Portugal ; Erasmus MC, Dept Internal Med, Sect Allergol, Rotterdam, Netherlands ; Univ Washington, Sch Med, Seattle, WA USA ; Helsinki Univ Hosp, Dept Allergy, Skin & Allergy Hosp, Helsinki, Finland ; GARD ARIA Coordinator, Geneva, Switzerland ; Med Univ Lodz, Dept Internal Med Asthma & Allergy, Barlicki Univ Hosp, Lodz, Poland ; Univ S Florida, Coll Med, Dept Internal Med, Div Allergy & Immunol, Tampa, FL 33612 USA ; James A Haley Vet Hosp, Tampa, FL USA ; 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Charite, Network Excellence, Global Allergy & Asthma European Network GA2LEN, D-13353 Berlin, Germany ; Universidade Federal de São Paulo, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, São Paulo, Brazil ; Web of Science

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