Phenotypic characteristics of aged CD4+ CD28null T lymphocytes are determined by changes in the whole-genome DNA methylation pattern

Abstract

This work is supported by Plan Nacional de I+D+I 2008–2011 and European Union Fondos Feder; Instituto de Salud Carlos III (grant number PI12/02587 and PI16/01318); Red Española de Investigación Renal (REDinREN) (grant number RD12/0021/0018 and 0021, and RD16/0009/0020), Plan de Ciencia, Tecnología e Innovación 2013-2017 del Principado de Asturias (reference GRUPIN-14-030), by the Government of the Basque Country (Etortek Research Programs 2008/2015) the Innovation Technology Department of Bizkaia.