Selective Fluorogenic Sensing of As(III) Using Aptamer-Capped Nanomaterials

Abstract

[EN] Organic-inorganic hybrid nanomaterials offer extremely valuable tools for monitoring many types of analytes in solution. Within this framework, aptamer-based nanomaterials for heavy metal detection are still very scarce. Herein, a novel sensing nanoprobe for the selective and sensitive detection of As(III) based on the combination of aptamers with mesoporous silica nanoparticles has been developed. The efficiency of the sensor is demonstrated in environmental conditions, showing a great potential in As(III) monitoring assays. ; The authors thank the financial support from the Spanish Government (projects MAT2015-64139-C4-1-R and AGL2015-70235-C2-2-R) and the Generalitat Valenciana (project GVA/2014/13). M.O. is grateful to the Universitat Politecnica for her PhD grant. A.B. thanks the Spanish Government for the finantial support "Juan de la Cierva-Incorporacion" (IJCI-2014-21534). C.C. thanks the Generalitat Valenciana for her postdoctoral contract VALi+D. ; Oroval, M.; Coll Merino, MC.; Bernardos Bau, A.; Marcos Martínez, MD.; Martínez-Máñez, R.; Shchukin, DG.; Sancenón Galarza, F. (2017). Selective Fluorogenic Sensing of As(III) Using Aptamer-Capped Nanomaterials. ACS Applied Materials & Interfaces. 9(13):11332-11336. https://doi.org/10.1021/acsami.6b15164 ; S ; 11332 ; 11336 ; 9 ; 13