An Interactive Model of Communication between Abiotic Nanodevices and Microorganisms

Abstract

"This is the peer reviewed version of the following article: Luis, B., Llopis-Lorente, A., Rincón, P., Gadea, J., Sancenón, F., Aznar, E., Villalonga, R., Murguía, J. R., & Martínez-Máñez, R. (2019). An Interactive Model of Communication between Abiotic Nanodevices and Microorganisms. Angewandte Chemie International Edition, 58(42), 14986 14990. https://doi.org/10.1002/anie.201908867, which has been published in final form at https://doi.org/10.1002/anie.201908867. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving." ; [EN] The construction of communication models at the micro¿/nanoscale involving abiotic nanodevices and living organisms has the potential to open a wide range of applications in biomedical and communication technologies. However, this area remains almost unexplored. Herein, we report, as a proof of concept, a stimuli¿responsive interactive paradigm of communication between yeasts (as a model microorganism) and enzyme¿controlled Janus Au¿mesoporous silica nanoparticles. In the presence of the stimulus, the information flows from the microorganism to the nanodevice, and then returns from the nanodevice to the microorganism as a feedback. ; B.dL. is grateful to the Spanish Government for her FPU PhD fellowship. The authors wish to thank the Spanish Government (projects RTI2018-100910-B-C41 (MCUI/AEI/FEDER, UE) and CTQ2017-87954-P), the Generalitat Valenciana (project PROMETEO2018/024), the Comunidad de Madrid (Project IND2017/BMD-7642) and CIBER-BBN (NANOCOM project) for support. ; De Luis-Fernández, B.; Llopis-Lorente, A.; Rincón, P.; Gadea Vacas, J.; Sancenón Galarza, F.; Aznar, E.; Villalonga, R. (2019). An Interactive Model of Communication between Abiotic Nanodevices and Microorganisms. Angewandte Chemie International Edition. 58(42):14986-14990. https://doi.org/10.1002/anie.201908867 ; S ; 14986 ; 14990 ; 58 ; 42 ; Waters, C. M., & Bassler, B. L. (2005). QUORUM SENSING: Cell-to-Cell Communication in Bacteria. Annual ...