Antifungal effect of essential oil components against Aspergillus niger when loaded into silica mesoporous supports

Abstract

Essential oil components (EOCs) are known for their antifungal properties; however, their high volatility limits their application as antimicrobial agents. Strategies used for controlling the volatility of EOCs include encapsulation or loading into porous materials. This study evaluated the in vitro antifungal activity of selected EOCs (carvacrol, cinnamaldehyde, eugenol and thymol) against the fungus Aspergillus niger when loaded into MCM-41 and b-cyclodextrin (b-CD). RESULTS: Carvacrol and thymol in Mobil Composition of Matter No. 41 (MCM-41) displayed remarkable enhanced antifungal properties in comparison to the pure or b- CD-encapsulated EOCs. In fact, carvacrol and thymol were able to maintain antifungal activity and inhibit fungal growth for 30 days, suggesting better applicability of these EOCs as natural preservatives. CONCLUSIONS: The sustained antifungal effect of EOCs encapsulated into silica mesoporous supports was described. ; The authors wish to express their gratitude to the Government of the Czech Republic (Postdok CZU: ESF and MEYS CZ.1.07/2.3.00/30.0040), to CIGA (Project number: 20132024) and to the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (research project RVO: 61388963). Beth Green is thanked for language control. ; Bernardos Bau, A.; Marina, T.; Zacek, P.; Pérez-Esteve, É.; Martínez-Máñez, R.; Lhotka, M.; Kourimská, L. (2015). Antifungal effect of essential oil components against Aspergillus niger when loaded into silica mesoporous supports. Journal of the Science of Food and Agriculture. 95(14):2824-2831. https://doi.org/10.1002/jsfa.7022 ; S ; 2824 ; 2831 ; 95 ; 14