Cocaine: Scientific and Social Dimensions

Cocaine in perspective / Griffith Edwards -- Cocaine's history, especially the American experience / David F. Musto -- Epidemiological research on cocaine use in the USA / James C. Anthony -- Cocaine problems in the coca-growing countries of South America / Juan Carlos Negrete -- Are there casual users of cocaine? / Charles D. Kaplan, Bert Bieleman and Warren D. TenHouten -- Molecular pharmacology of cocaine: a dopamine hypothesis and its implications / Michael J. Kuhar -- Neurobiology of cacaine-induced reinforcement / H. Christian Fibiger, Anthony G. Phillips and Erin E. Brown -- How toxic is cocaine? / Neal L. Benowitz -- Determinants of cocaine self-administration by laboratory animals / William L. Woolverton -- Self-administration of cocaine by humans: a laboratory perspective / Marian W. Fischman and Richard W. Foltin -- AIDS and HIV infection in cocaine users -- Treatment of cocaine abuse: pharmacotherapy / Herbert D. Kleber -- Psychotherapy for cocaine dependence / Charles P. O'Brien [and others] -- Alternative strategies / Reese T. Jones -- Economics of drug use and abuse / Alan Maynard -- Formulating policies on the non-medical use of cocaine / Harold Kalant -- Drug use and abuse: the ethical issues / Brenda Almond -- Summing-up / Griffith Edwards.

Cocaine in perspective / Griffith Edwards -- Cocaine's history, especially the American experience / David F. Musto -- Epidemiological research on cocaine use in the USA / James C. Anthony -- Cocaine problems in the coca-growing countries of South America / Juan Carlos Negrete -- Are there casual users of cocaine? / Charles D. Kaplan, Bert Bieleman and Warren D. TenHouten -- Molecular pharmacology of cocaine: a dopamine hypothesis and its implications / Michael J. Kuhar -- Neurobiology of cacaine-induced reinforcement / H. Christian Fibiger, Anthony G. Phillips and Erin E. Brown -- How toxic is cocaine? / Neal L. Benowitz -- Determinants of cocaine self-administration by laboratory animals / William L. Woolverton -- Self-administration of cocaine by humans: a laboratory perspective / Marian W. Fischman and Richard W. Foltin -- AIDS and HIV infection in cocaine users -- Treatment of cocaine abuse: pharmacotherapy / Herbert D. Kleber -- Psychotherapy for cocaine dependence / Charles P. O'Brien [and others] -- Alternative strategies / Reese T. Jones -- Economics of drug use and abuse / Alan Maynard -- Formulating policies on the non-medical use of cocaine / Harold Kalant -- Drug use and abuse: the ethical issues / Brenda Almond -- Summing-up / Griffith Edwards

Cocaine poses interesting problems for neurophysiologists and neuropharmacologists and there is important new data on the effects of cocaine on the brain (its initial site of action at the cellular level now appearing to be the dopamine transporter). Includes chapters on the far-reaching toxic effects of cocaine, on the epidemiology and the economics of drug addiction, on the past and present use of cocaine in the U.S. and in South America, and on the moral issues raised by drug use and abuse