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Shipping list no.: 2014-0252-P. ; Includes bibliographical references. ; Mode of access: Internet.

"5M-4-47." ; Title from cover. ; Mode of access: Internet. ; In cooperation with the United States Department of Agriculture.

Elongases of very long-chain fatty acids (Elovl) catalyse the rate-limiting step of the elongation pathway that results in net 2C elongation of pre-existing fatty acyl chains. As the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFA) is particularly relevant in fish, Elovl involved in the pathway have been investigated in various studies. Here we report the molecular cloning, functional characterisation and tissue distribution of two distinct elovl-like cDNAs isolated from the herbivorous marine teleost Siganus canaliculatus. Unlike the carnivorous marine fish previously investigated, we hypothesise that the rabbitfish has an enhanced LC-PUFA biosynthetic capability as previously anticipated in a former study on fatty acyl desaturases (Fad). The results of the present study showed that rabbitfish expresses at least two elovl cDNAs, which have high homology in sequence and function to Elovl5 and Elovl4 elongases that have been investigated previously in other fish species. Furthermore, the results confirm that the activities of the Elovl5 and Elovl4 enzymes enable rabbitfish to perform all the elongation reactions required for the biosynthesis of the physiologically essential C 20-22 LC-PUFA including eicosapentaenoic (20:5n-3), arachidonic (20:4n-6) and docosahexaenoic (22:6n-3, DHA) acids, as well as the less common very long-chain fatty acids (>C 24). Rabbitfish is thus the first marine teleost in which genes encoding Fad and Elovl enzymes, with all the activities required for the production of DHA from C 18 PUFA, have been characterised. © 2012 Elsevier B.V. ; National Natural Science Foundation of China (NSFC): 31110103913 y 30972266. NSFC-Royal Society: JP090748 y 31011130156. Foundation for High Level Talents of Guangdong Universities: 2010-79. Research Fund for the Doctoral Program of Higher Education of China: 20104402110002. European Community: PERG08-GA-2010-276916, LONGFA. Ministerio de Ciencia e Innovación, Spanish Government. ; Peer Reviewed

Book review Russian Culture in War and Revolution, 1914–22. Book 1. Popular Culture, the Arts, and Institutions; Book 2. Political Culture, Identities, Mentalities, and Memory (Russia's Great War and Revolution, vol. 1). Ed. by Murray FRAME, Boris KOLONITSKII, Steven G. MARKS and Melissa K. STOCKDALE. Bloomington, IN: Slavica Publishers, 2014. – xxiv+426 [+42] and xviii+370 [+56] pp. ISBN 978-0-89357-423-9; 978-0-89357-424-6