Suchergebnisse

Volltext // 2018 digitalisiert von: Bayerische Staatsbibliothek, München. Exemplar mit der Signatur: München, Bayerische Staatsbibliothek -- 4 Gall.rev. 6 c,2-38

Volltext // 2016 digitalisiert von: Bayerische Staatsbibliothek, München. Exemplar mit der Signatur: München, Bayerische Staatsbibliothek -- 4 Gall.rev. 6 c,2-34

Edited by Eugene C. Barker. cf. Foreword. ; "References for further reading" at end of each chapter except the first. ; Mode of access: Internet. ; 2

The countries of the European Union have decided to share a peaceful future based on common values. However, there are still disputes over the understanding of the most fundamental issues related to the protection of human rights, including protection of the right to life. The author shows that the source of European culture is Christian. However, it is not the only source of shaping the values of Europe. As an example, she cites the differentiation of constitutional legal regulations or controversies related to the jurisprudence of the ECHR. She analyzes the judgment of the Polish Constitutional Tribunal declaring the unconstitutionality of the provisions allowing abortion if prenatal tests or other medical conditions indicate a high probability of a severe and irreversible fetal impairment or an incurable life-threatening disease. This judgment caused enormous opposition from a part of the society. This problem proves that a compromise has not yet been made on the issue of abortion. It is, therefore, difficult to claim that human rights protected in the European Union are given universal meaning.

Elongases of very long-chain fatty acids (Elovl) catalyse the rate-limiting step of the elongation pathway that results in net 2C elongation of pre-existing fatty acyl chains. As the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFA) is particularly relevant in fish, Elovl involved in the pathway have been investigated in various studies. Here we report the molecular cloning, functional characterisation and tissue distribution of two distinct elovl-like cDNAs isolated from the herbivorous marine teleost Siganus canaliculatus. Unlike the carnivorous marine fish previously investigated, we hypothesise that the rabbitfish has an enhanced LC-PUFA biosynthetic capability as previously anticipated in a former study on fatty acyl desaturases (Fad). The results of the present study showed that rabbitfish expresses at least two elovl cDNAs, which have high homology in sequence and function to Elovl5 and Elovl4 elongases that have been investigated previously in other fish species. Furthermore, the results confirm that the activities of the Elovl5 and Elovl4 enzymes enable rabbitfish to perform all the elongation reactions required for the biosynthesis of the physiologically essential C 20-22 LC-PUFA including eicosapentaenoic (20:5n-3), arachidonic (20:4n-6) and docosahexaenoic (22:6n-3, DHA) acids, as well as the less common very long-chain fatty acids (>C 24). Rabbitfish is thus the first marine teleost in which genes encoding Fad and Elovl enzymes, with all the activities required for the production of DHA from C 18 PUFA, have been characterised. © 2012 Elsevier B.V. ; National Natural Science Foundation of China (NSFC): 31110103913 y 30972266. NSFC-Royal Society: JP090748 y 31011130156. Foundation for High Level Talents of Guangdong Universities: 2010-79. Research Fund for the Doctoral Program of Higher Education of China: 20104402110002. European Community: PERG08-GA-2010-276916, LONGFA. Ministerio de Ciencia e Innovación, Spanish Government. ; Peer Reviewed

Reproducción digital. Madrid : Ministerio de Defensa. Subdirección General de Publicaciones y Patrimonio Cultural, 2020