We present a brief archaeological summary of the main phases of cultural and social change in the Western, Central, and South Asia ca. 4000-1500 BCE as a contextual framework for the findings presented in Damgaard et al. 2018. We stress the role of the Caucasus as a conduit in Western Asia linking the steppe and Eastern Europe with Anatolia, Syria, Iraq, and Iran. We track the emergence of the Bactria-Margiana Archaeological Complex (BMAC) in Central Asia as a cultural melting pot between the steppe and the sown lands during a period of more than a millennium. And we highlight indicators of cultural and commercial exchange, tracking developments in technology as well as social and political organization that came about as part of complex processes of interaction in a region stretching from South Asia to the Mediterranean.
Scale is an overlooked issue in the research on interactive governance. This book takes up the important task of investigating the scalar dimensions of collaborative governance in networks, partnerships, and other interactive arenas and explores the challenges of operating at a single scale, across or at multiple scales and of moving between scales. First published as a special issue of Policy & Politics, the volume explores the role of scale and scaling in a wide range of policy areas, including employment policy, water management, transportation planning, public health, university governance, artistic markets, child welfare and humanitarian relief. Cases are drawn from Asia, Australia, Europe, and North and South America and span all levels from local to global. Together, the theoretical framework and the empirical case studies sensitize us to the tensions that arise between scales of governance and to the challenges of shifting from one scale of governance to another
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Cable bacteria are long, multicellular micro-organisms that are capable of transporting electrons from cell to cell along the longitudinal axis of their centimeter-long filaments. The conductive structures that mediate this long-distance electron transport are thought to be located in the cell envelope. Therefore, this study examines in detail the architecture of the cell envelope of cable bacterium filaments by combining different sample preparation methods (chemical fixation, resin-embedding, and cryo-fixation) with a portfolio of imaging techniques (scanning electron microscopy, transmission electron microscopy and tomography, focused ion beam scanning electron microscopy, and atomic force microscopy). We systematically imaged intact filaments with varying diameters. In addition, we investigated the periplasmic fiber sheath that remains after the cytoplasm and membranes were removed by chemical extraction. Based on these investigations, we present a quantitative structural model of a cable bacterium. Cable bacteria build their cell envelope by a parallel concatenation of ridge compartments that have a standard size. Larger diameter filaments simply incorporate more parallel ridge compartments. Each ridge compartment contains a ∼50 nm diameter fiber in the periplasmic space. These fibers are continuous across cell-to-cell junctions, which display a conspicuous cartwheel structure that is likely made by invaginations of the outer cell membrane around the periplasmic fibers. The continuity of the periplasmic fibers across cells makes them a prime candidate for the sought-after electron conducting structure in cable bacteria. ; This research was financially supported by the European Research Council under the European Union's Seventh Framework Program (FP/2007-2013) through ERC Grant 306933 (FM), the Research Foundation Flanders (FWO project grant G031416N to FM and JM), and the Netherlands Organization for Scientific Research (VICI grant 016.VICI.170.072 to FM). RB is supported by an aspirant grant from Research Foundation Flanders. LN, AB, LD, and TB were supported by the Danish Council for Independent Research, Technology and Production Sciences—project on Microcable-based Nanoelectronics and the Danish National Research Foundation Center of Excellence CEM—Center for Electromicrobiology.
Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modern breeding impacted genetic diversity more dramatically than the previous millennia of human management. Genome-wide data from 278 ancient equids provide insights into how ancient equestrian civilizations managed, exchanged, and bred horses and indicate vast loss of genetic diversity as well as the existence of two extinct lineages of horses that failed to contribute to modern domestic animals. ; Taylor Family-Asia Foundation Endowed Chair in Ecology and Conservation Biology. M.L. was supported by a Marie-Curie Individual Fellowship (MSCA-IF-67852). L.L. was supported by the Estonian Research Council (PRG29). C.L. was supported by FCT (SFRH/BPD/100511/2014). P.K., N.R., and O.M. were supported by the Ministry of Educations and Science of Russian Federation (33.1907, 2017/P4) and the Russian Scientific Foundation (18-18-00137). T.M.-B. was supported by the BFU2017-86471-P (MINECO/FEDER, UE), the U01 MH106874 grant, Howard Hughes International Early Career, Obra Social ''La Caixa,'' and Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat de Catalunya. V.P. was supported by Russian Science Foundation (16-18-10265) e Danish National Research Foundation (DNRF94), the Initiative d'Excellence Chaires d'attractivite´ , Universite´ de Toulouse (OURASI), the International Highly Cited Research Group Program (HCRC#15-101), Deanship of Scientific Research, King Saud University, the Villum Fonden miGENEPI research project, the Swiss National Science Foundation (CR13I1_140638), the Research Council of Norway (project 230821/F20); the investigation grant HAR2016-77600-P, Ministerio de Economía y Competitividad, Spain, and the National Science Foundation ANS1417036). This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement 681605)
Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modern breeding impacted genetic diversity more dramatically than the previous millennia of human management. ; B.B. was supported by the Taylor Family-Asia Foundation Endowed Chair in Ecology and Conservation Biology. M.L. was supported by a Marie-Curie Individual Fellowship (MSCA-IF-67852). L.L. was supported by the Estonian Research Council (PRG29). C.L. was supported by FCT (SFRH/BPD/100511/2014). P.K., N.R., and O.M. were supported by the Ministry of Educations and Science of Russian Federation (33.1907, 2017/Π4) and the Russian Scientific Foundation (18-18-00137). T.M.-B. was supported by the BFU2017-86471-P (MINECO/FEDER, UE), the U01 MH106874 grant, Howard Hughes International Early Career, Obra Social "La Caixa," and Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat de Catalunya. V.P. was supported by Russian Science Foundation (16-18-10265). This research received support from the SYNTHESYS Project (http://www.synthesys.info/), which is financed by European Community Research Infrastructure Action under the Seventh Framework "Capacities" Programme. This work was supported by the Danish National Research Foundation (DNRF94), the Initiative d'Excellence Chaires d'attractivité, Université de Toulouse (OURASI), the International Highly Cited Research Group Program (HCRC#15-101), Deanship of Scientific Research, King Saud University, the Villum Fonden miGENEPI research project, the Swiss National Science Foundation (CR13I1_140638), the Research Council of Norway (project 230821/F20); the investigation grant HAR2016-77600-P, Ministerio de Economía y Competitividad, Spain, and the National Science Foundation (ANS-1417036). This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement 681605). ; Peer reviewed
In 1985 the French government created a unique circuit for the dissemination of doctoral theses: References went to a national database "Téléthèses" whereas the documents were distributed to the university libraries in microform. In the era of the electronic document this French network of deposit of and access to doctoral theses is changing. How do you discover and locate a French thesis today, how do you get hold of a paper copy and how do you access the full electronic text? What are the catalogues and databases referencing theses since the disappearance of "Téléthèses"? Where are the archives, and are they open? What is the legal environment that rules the emerging structures and tools? This paper presents national plans on referencing and archiving doctoral theses coordinated by the government as well as some initiatives for creating full text archives. These initiatives come from universities as well as from research institutions and learned societies. "Téléthèses" records have been integrated in a union catalogue of French university libraries SUDOC. University of Lyon-2 and INSA Lyon developed procedures and tools covering the entire production chain from writing to the final access in an archive: "Cyberthèses" and "Cither". The CNRS Centre for Direct Scientific Communication at Lyon (CCSD) maintains an archive ("TEL") with about 2000 theses in all disciplines. Another repository for theses in engineering, economics and management called "Pastel" is proposed by the Paris Institute of Technology (ParisTech), a consortium of 10 engineering and commercial schools of the Paris region.