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Enacted Legislative Findings and the Deference Problem
In: Georgetown Law Journal, Forthcoming
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The Obama Justice Department's Merger Enforcement Record: An Armchair Reply to Baker and Shapiro
In: U of Michigan Public Law Research Paper No. 279
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Working paper
IP's Advantages over Antitrust
In: The Global Limits of Competition Law, S. 117-126
Search Neutrality as an Antitrust Principle
In: U of Michigan Law & Econ, Empirical Legal Studies Center Paper No. 11-016
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Working paper
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The Democrats' 'Better Deal' Is Neither Better Nor a Deal
In: New York University Journal of Law and Business, Forthcoming
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State Action Immunity and Section 5 of the FTC Act
In: Michigan Law Review, Band 115, Heft 3
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Responsibility, freedom and social justice
In: Fairness, Responsibility, and Welfare, S. 245-276
Proposals for a gold-based monetary system: Pro and Con
In: Congressional digest: an independent publication featuring controversies in Congress, pro & con. ; not an official organ, nor controlled by any party, interest, class or sect, Band 61, Heft 6, S. 163-192
ISSN: 0010-5899
World Affairs Online
Efficacy of Colistin Impregnated Beads to Prevent Multi-drug Resistant A. baumannii Implant-Associated Osteomyelitis
Osteomyelitis (OM) from multidrug-resistant (MDR) Acinetobacter has emerged in >30% of combat-related injuries in Iraq and Afghanistan. While most of these strains are sensitive to colistin, the drug is not availible in bone void fillers for local high-dose delivery. To address this we developed a mouse model with MDR strains isolated from wounded military personnel. In contrast to S. aureus OM, which is osteolytic and characterized by biofilm in necrotic bone, A. baumannii OM results in blastic lesions that do not contain apparent biofilm. We also found that mice mount a specific IgG response against 3 proteins (40, 47 & 56KDa) regardless of the strain used, suggesting that these may be immunuo-dominant antigens. PCR for the A. baumannii specific parC gene confirmed a 100% infection rate with 75% of the MDR strains, and in vitro testing confirmed that all strains were sensitive to colistin. We also developed a real-time quantitative PCR (RTQ-PCR) assay that could detect as few as 10 copies of parC in a sample. To demonstrate the efficacy of colistin prophylaxis in this model, mice were treated with either parenteral colistin (0.2mg colistinmethate i.m. for 7 days), local colistin (PMMA bead impregnated with 1.0mg colistin sulfate), or an unloaded PMMA bead control. While the parenteral colistin failed to demonstrate any significant effects vs. the placebo, the colistin PMMA bead significantly reduced the infection rate such that only 29.2% of the mice had detectable levels of parC at 19 days (p<0.05 vs. i.m. colistin and placebo).
BASE
Brief of Amici Curiae Antitrust Law Professors in O'Bannon v. NCAA
In: University of Illinois College of Law Legal Studies Research Paper No. 15-24
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Working paper
Joint Submission of Antitrust Economists, Legal Scholars, and Practitioners to the House Judiciary Committee on the State of Antitrust Law and Implications for Protecting Competition in Digital Markets
In: University of Missouri School of Law Legal Studies Research Paper Forthcoming
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Working paper