Suchergebnisse

The objective of this study was to investigate the current status and trends in antidepressant use and expenditure in China from 2013 to 2018. The study had a retrospective design based on prescribing data on antidepressant drugs, which was sourced from the Hospital Prescription Analysis Cooperative Project. The trends in hospital visits and corresponding expenditure on antidepressant drugs were examined. Subgroup analyses were carried out by sex, age, and drug class. A total of 1,795,230 outpatient prescriptions were collected from 79 hospitals in six major cities in China. Hospital visits with antidepressant prescriptions rose significantly from 244,626 in 2013 to 348,718 in 2018, reflecting a 42.6% increase (P < 0.05). The antidepressant expenditure also rose, increasing from 48.0 million Chinese yuan in 2013 to 64.8 million Chinese yuan in 2018. There were approximately 1.6 times more antidepressant prescriptions written for women than for men. The most frequent age category for antidepressant prescriptions was 45–64 years. The most commonly prescribed antidepressants were selective serotonin reuptake inhibitors (N06AB) and other antidepressants (N06AX), whereas tricyclic antidepressants (N06AA) accounted for only a small part of the total antidepressant prescriptions. Flupentixol/melitracen and escitalopram were the most frequently prescribed antidepressants. Antidepressant prescribing rates continue to increase in China, although the prescribing patterns have changed over the past few years. The wide use of expensive antidepressants and those with weak clinical evidence raises concerns regarding the rational use of antidepressants. This study provides a basis for future stewardship by the government and medical institutions.

Global to local environmental policy-making is increasingly evidenced-based. Knowledge management (KM) is increasingly used by environmental scientists and policymakers, to deliver evidence-based policy and practice. There is thus an urgent need to identify whether and how knowledge is exchanged between knowledge producers and users in environmental science fields. Here we apply an assessment framework developed in social medicine to identify what forms of environmental knowledge are exchanged, and why and how they are exchanged. We focussed on China, as international research to better manage Chinese ecosystem services is rapidly-increasing, yet, how to best integrate this into political decision-making and the public realm remains a challenge. How KM is practiced in China is unknown. We addressed this through: 1) a systematic analysis of published KM research in China compared to global trends; 2) evaluating KM for environmental policy and management in China; 3) quantitative surveys of Chinese (n = 72) and British (n = 16) scientists researching Chinese environmental problems. The systematic literature review of two databases identified two key findings. One, of 291 papers that considered KM there were no papers in the environmental sector examining the science-policy-practice interface in China. Two, only 13 of 423 potentially relevant papers explicitly examined KM for environmental topics, notably for agriculture and information exchange (the 'What?'). Most papers reported a one-way interaction between scientists and users (the 'How?'), used to change practice (the 'Why?'). Our survey showed significantly-less awareness and use of two-way knowledge exchange (KE) methods by Chinese scientists. The paucity of documented KM research and limited evidence for two-way interaction show KE at the environmental science-policy-practice interface in China is limited. Promotion of KE practice may benefit environmental policy-making in China. We have also shown that conceptual frameworks for mapping and assessing KE ...

Global to local environmental policy-making is increasingly evidenced-based. Knowledge management (KM) is increasingly used by environmental scientists and policymakers, to deliver evidence-based policy and practice. There is thus an urgent need to identify whether and how knowledge is exchanged between knowledge producers and users in environmental science fields. Here we apply an assessment framework developed in social medicine to identify what forms of environmental knowledge are exchanged, and why and how they are exchanged. We focussed on China, as international research to better manage Chinese ecosystem services is rapidly-increasing, yet, how to best integrate this into political decision-making and the public realm remains a challenge. How KM is practiced in China is unknown. We addressed this through: 1) a systematic analysis of published KM research in China compared to global trends; 2) evaluating KM for environmental policy and management in China; 3) quantitative surveys of Chinese (n = 72) and British (n = 16) scientists researching Chinese environmental problems. The systematic literature review of two databases identified two key findings. One, of 291 papers that considered KM there were no papers in the environmental sector examining the science-policy-practice interface in China. Two, only 13 of 423 potentially relevant papers explicitly examined KM for environmental topics, notably for agriculture and information exchange (the 'What?'). Most papers reported a one-way interaction between scientists and users (the 'How?'), used to change practice (the 'Why?'). Our survey showed significantly-less awareness and use of two-way knowledge exchange (KE) methods by Chinese scientists. The paucity of documented KM research and limited evidence for two-way interaction show KE at the environmental science-policy-practice interface in China is limited. Promotion of KE practice may benefit environmental policy-making in China. We have also shown that conceptual frameworks for mapping and assessing KE practice from social medicine can be usefully adapted for examining environmental science – policy interfaces.