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In: Air quality, atmosphere and health: an international journal, Band 15, Heft 12, S. 2231-2238
ISSN: 1873-9326
In: Air quality, atmosphere and health: an international journal, Band 13, Heft 10, S. 1223-1234
ISSN: 1873-9326
OBJECTIVE: To use high-resolution metabolomics (HRM) to identify metabolic changes in military personnel associated with deployment to Balad, Iraq, or Bagram, Afghanistan. METHODS: Pre- and post-deployment samples were obtained from the Department of Defense Serum Repository (DoDSR). HRM and bioinformatics were used to identify metabolic differences associated with deployment. RESULTS: Differences at baseline (pre-deployment) between personnel deployed to Bagram compared to Balad or Controls included sex hormone and keratan sulfate metabolism. Deployment to Balad was associated with alterations to amino acid and lipid metabolism, consistent with inflammation and oxidative stress, and pathways linked to metabolic adaptation and repair. Difference associated with deployment to Bagram included lipid pathways linked to cell signaling and inflammation. CONCLUSIONS: Metabolic variations in pre- and post-deployment are consistent with deployment-associated responses to air pollution and other environmental stressors.
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In: Environmental science and pollution research: ESPR
ISSN: 1614-7499
In: Environmental science and pollution research: ESPR, Band 29, Heft 39, S. 59263-59286
ISSN: 1614-7499
In: Air quality, atmosphere and health: an international journal, Band 11, Heft 7, S. 791-799
ISSN: 1873-9326
In: Environmental science and pollution research: ESPR, Band 24, Heft 20, S. 16860-16868
ISSN: 1614-7499
In: Environmental science and pollution research: ESPR, Band 27, Heft 31, S. 38631-38643
ISSN: 1614-7499
In: Ecotoxicology and environmental safety: EES ; official journal of the International Society of Ecotoxicology and Environmental safety, Band 212, S. 111986
ISSN: 1090-2414
In: Environmental science and pollution research: ESPR, Band 29, Heft 57, S. 85586-85594
ISSN: 1614-7499
In: Air quality, atmosphere and health: an international journal, Band 6, Heft 2, S. 333-355
ISSN: 1873-9326
In: Air quality, atmosphere and health: an international journal, Band 5, Heft 1, S. 9-62
ISSN: 1873-9326