Preston king's ideology of order
In: Politics: Australasian Political Studies Association journal, Band 13, Heft 1, S. 188-192
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In: Politics: Australasian Political Studies Association journal, Band 13, Heft 1, S. 188-192
In: Pacific affairs, Band 46, Heft 4, S. 609
ISSN: 0030-851X
In: Political science, Band 21, Heft 2, S. 54-57
ISSN: 2041-0611
In: American anthropologist: AA, Band 67, Heft 1, S. 102-103
ISSN: 1548-1433
In: American anthropologist: AA, Band 65, Heft 2, S. 400-400
ISSN: 1548-1433
In: The political quarterly: PQ, Band 68, Heft 1, S. 108-110
ISSN: 0032-3179
In: Political science, Band 41, Heft 2, S. 51, 69
ISSN: 0112-8760, 0032-3187
In: Accounting historians journal: a publication of the Academy of Accounting Historians Section of the American Accounting Association, Band 42, Heft 2, S. 137-140
ISSN: 2327-4468
Accounting historians often encounter the arduous and interesting task of uncovering the truth insulated by myriad layers of embellishment. In the spirit of full disclosure, like Don Quixote of old, we set out in search of the truth from three related perspectives—officers of the court, financial auditors and athletic officials. Truth, shaded by the human element, is the basis for their significant decisions impacting society.
In: Pacific affairs: an international review of Asia and the Pacific, Band 34, Heft 2, S. 220
ISSN: 1715-3379
In: Political science, Band 52, Heft 1, S. 89-90
ISSN: 0112-8760, 0032-3187
In: Pacific affairs: an international review of Asia and the Pacific, Band 44, Heft 2, S. 319
ISSN: 1715-3379
In: Pacific affairs: an international review of Asia and the Pacific, Band 46, Heft 4, S. 609
ISSN: 1715-3379
DNA methylation is an epigenetic modification involved in regulatory processes such as cell differentiation during development, X-chromosome inactivation, genomic imprinting and susceptibility to complex disease. However, the dynamics of DNA methylation changes between humans and their closest relatives are still poorly understood. We performed a comparative analysis of CpG methylation patterns between 9 humans and 23 primate samples including all species of great apes (chimpanzee, bonobo, gorilla and orangutan) using Illumina Methylation450 bead arrays. Our analysis identified ∼800 genes with significantly altered methylation patterns among the great apes, including ∼170 genes with a methylation pattern unique to human. Some of these are known to be involved in developmental and neurological features, suggesting that epigenetic changes have been frequent during recent human and primate evolution. We identified a significant positive relationship between the rate of coding variation and alterations of methylation at the promoter level, indicative of co-occurrence between evolution of protein sequence and gene regulation. In contrast, and supporting the idea that many phenotypic differences between humans and great apes are not due to amino acid differences, our analysis also identified 184 genes that are perfectly conserved at protein level between human and chimpanzee, yet show significant epigenetic differences between these two species. We conclude that epigenetic alterations are an important force during primate evolution and have been under-explored in evolutionary comparative genomics. © 2013 Hernando-Herraez et al. ; TMB is supported by the European Research Council (ERC Starting Grant, StG_20091118) and the Spanish Government (BFU2011-28549). AJS is supported by NIH grants 1R01DA033660, 1R01HG006696, and a grant from the Alzheimer's Association (2012ALZNIRG69983). IHH is supported by the European Social Fund, AGAUR (Generalitat de Catalunya, Spain) and the Spanish National Research Council (CSIC). We also thank the Spanish Government for the grant BFU2009-13409-C02-02 to AN and the Barcelona Zoo (Ajuntament de Barcelona) for an award to JPM. ; Peer Reviewed
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With increasing demand for red meat in Tanzania comes heightened potential for zoonotic infections in animals and humans that disproportionately affect poor communities. A range of frontline government employees work to protect public health, providing services for people engaged in animal-based livelihoods (livestock owners and butchers), and enforcing meat safety and food premises standards. In contrast to literature which emphasises the inadequacy of extension support and food safety policy implementation in low- and middle-income countries, this paper foregrounds the 'street-level diplomacy' deployed by frontline actors operating in challenging contexts.
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