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The article is devoted to a comprehensive study of the essence of understanding the concept of "The Asia-Pacific region" and analysis of the experience of implementing regional development projects in the modern conditions. It is established that among researchers there is still no single approach to the concept of "APR". The article uses the understanding of "Asia-Pacific" in the narrow sense: the countries of Northeast Asia: China, Japan, South and North Korea and ten countries of Southeast Asia, united in the regional organization ASEAN. All these countries make a significant contribution to interstate relations in the Pacific ocean, so the trends of stability prevail over the trends of destabilization of political and economic processes that formthe basis of a potential world center. It is established that after the end of the Cold War, the Asia-Pacific region could be considered the most stable region in the world, which has undergone a period of long-term economic development without obvious conflicts. It is noted that the Asia-Pacific region entered the path of development of integration processes much later than other regions of the world (except ASEAN). The article also notes and substantiates the idea that the uniqueness (phenomenon) of Asia-Pacific economic integration lies in the existence of soft integration schemes, which are reflected in the formation of economic growth zones in East Asia (for example, ASEAN, APEC). It is established that in the region there is an intensive formation of regional forums and mechanisms that contribute to the close relationship between the main actors of the region and strengthen its position in the world political process. The article also highlights and analyzes the trends of political regionalism in the Asian part of the Asia-Pacific region: strengthening China's role in the regional political process; coexistence of two models of cooperation in the region: transnational cooperation and interstate competition; shifting priority in regional security from external threats to internal ones, and aspects of political, economic, social and environmental cooperation come to the fore. ; Стаття присвячена комплексному дослідженню сутності розуміння поняття «Азіатсько-Тихоокеанський регіон», аналізу досвіду впровадження проектів розвитку регіону в сучасних умовах. Встановлено, що серед дослідників і дотепер не існує єдиного підходу до поняття «АТР». У межах статті термін «АТР» уживається у вузькому значенні: це країни Північно-Східної Азії: Китай, Японія, Південна і Північна Корея, десять країн Південно-Східної Азії, об'єднаних у регіональну організацію - Асоціацію держав Південно-Східної Азії. Усі ці країни вносять значний вклад у міждержавні відносини в Тихому океані, тому тенденції стабільності переважають над тенденціями дестабілізації політичних і економічних процесів, які формують основу потенційного світового центру. Встановлено, що після завершення холодної війни Азіатсько-Тихоокеанський регіон можна було вважати найстабільншгим регіоном у світі, який пройшов період тривалого економічного розвитку без очевидних конфліктів. Зазначено, що Азіатсько-Тихоокеанський регіон вступив на шлях розвитку інтеграційних процесів набагато пізніше за інші регіони світу (окрім Асоціації держав Південно-Східної Азії.). Також у статті зазначається й обґрунтовується думка, що унікальність (феномен) азіатсько-тихоокеанської економічної інтеграції полягає в наявності м'яких схем інтеграції, які знайшли прояв у формуванні зон економічного зростання у Східній Азії (на прикладі Асоціації держав Південно-Східної Азії, Азіатсько-Тихоокеанського економічного співробітництва). Встановлено, що в регіоні відбувається інтенсивне формування регіональних форумів та механізмів, які сприяють тісним відносинам між основними суб'єктами регіону і посиленню його позицій у світовому політичному процесі. Також у статті виокремлено та проаналізовано тренди політичного регіоналізму в азіатській частині Азіатсько-Тихоокеанського регіону: посилення ролі Китаю в регіональному політичному процесі; співіснування двох моделей співпраці в регіоні: транснаціональну кооперацію та міждержавну конкуренцію; перенесення пріоритету в питаннях регіональної безпеки із зовнішніх загроз на внутрішні, і на перший план виходять аспекти політичної, економічної, соціальної й екологічної співпраці.

The statistics have been assigned the factors of politics (political and legal, policy, social, environmental and global) and internal relations (organizational and economic personnel). On the basis of the recognized requirements and the internal potential functions, the power supply and the power industry, a number of macro-economic and non-technical changes are violated, which are directly related to the lack of safety and security. It has been reinstated, right now, that realizatsion of economical influx on macro may: concentrate on the key aspects of stream problems of electricity generation for the consolidation of system interconnections; include the selection of specialized strategies and the program for developing galactic products in all regions of the region; transfer of investment, investment and innovation processes, as well as a lot of warehouse structural policy; base on the demonopolization of the national energy market and the transition to the most advanced models of functional functions. Prior to direct management of energy efficiency, the following information was presented: detailed plans for innovative development plans, modernization, modernization, and economic knowledge; the establishment of a system for operational monitoring of key indicators of efficiency and effectiveness of electric energy; victorious investment components at the post-warehouse warehouse of the system of value; analysis of foreign gospodar practices, ix of experience in the framework of a specific initiative and the progressive transition to European energy standards. ; В статье определены факторы внешних (политико-правовые, конъюнктурные, социальные, экологические и глобализационные) и внутренних рисков (организационно-экономические, производственные и кадровые) деятельности предприятий электроэнергетики. На основе определенных внешних и внутренних потенциальных рисков функционирования предприятий электроэнергетики выделены ряд мер макроэкономического и микроэкономического характера, направленных на обеспечение качественной трансформации отечественных предприятий энергетической отрасли, в направлении обеспечения их устойчивого развития. Установлено, что направления реализации мер экономического воздействия на макроуровне имеют: сконцентрироваться на ключевых аспектах текущей проблематике отечественной электроэнергетики для устранения системных ограничений развития; включать в себя разработку профильных стратегий и программ развития предприятий отрасли на всех уровнях исполнительной власти; предусматривать интенсификацию инвестиционно-инновационных процессов как неотъемлемой составляющей структурной политики; базироваться на демонополизации национального энергорынка и перехода к более современных моделей его функционирования. К направлений совершенствования управленческой деятельности предприятий электроэнергетики отнесены: разработку конкретных планов инновационного развития предприятия, нацеленных на модернизацию, реновацию и экологизацию физически и морально устаревшего оборудования; создание системы оперативного мониторинга ключевых показателей эффективности деятельности электроэнергетических предприятий; использования инвестиционной компоненты в качестве постоянного компонента системы ценообразования; анализ зарубежных хозяйственных практик, их качественная имплементация в рамках конкретного предприятия и постепенный переход к европейским энергетическим стандартам. ; У статті визначено фактори зовнішніх (політико-правові, кон'юнктурні, соціальні, екологічні та глобалізаційні) та внутрішніх ризиків (організаційно-економічні, виробничі та кадрові) діяльності підприємств електроенергетики. На основі визначених зовнішніх та внутрішніх потенційних ризиків функціонування підприємств електроенергетики виокремлено ряд заходів макроекономічного та мікроекономічного характеру, спрямованих на забезпечення якісної трансформації вітчизняних підприємств енергетичної галузі, у напрямку забезпечення їх сталого розвитку. Встановлено, що напрямки реалізації заходів економічного впливу на макрорівні мають: концентруватися на ключових аспектах поточної проблематики вітчизняної електроенергетики задля усунення системних обмежень розвитку; включати в себе розробку профільних стратегій та програм розвитку підприємств галузі на всіх рівнях виконавчої влади; передбачати інтенсифікацію інвестиційно-інноваційних процесів як невід'ємної складової структурної політики; базуватися на демонополізації національного енергоринку та переходу до більш сучасних моделей його функціонування. До напрямків вдосконалення управлінської діяльності підприємств електроенергетики віднесено: розробку конкретних планів інноваційного розвитку підприємства, націлених на модернізацію, реновацію та екологізацію фізично та морально застарілого обладнання; створення системи оперативного моніторингу ключових показників ефективності діяльності електроенергетичних підприємств; використання інвестиційної компоненти у якості постійного складника системи ціноутворення; аналіз зарубіжних господарських практик, їх якісна імплементація у рамках конкретного підприємства та поступовий перехід до європейських енергетичних стандартів.

Abstrak Permasalahan remaja menjadi isu kompleks dan memerlukan kajian pemerintah untuk penyelesaiannya. Salah satu respon pemerintah dalam mengatasi permasalahan remaja yakni dengan membentuk Program Bina Keluarga Remaja (BKR) melalui Badan Kependudukan dan Keluarga Berencana Nasional (BKKBN) dengan berlandaskan hukum pada Peraturan Kepala BKKBN 109/PER/F2/2012 tentang Pedoman Pengelolaan Program BKR. Pelaksanaan Program BKR pada BKR Mentikan II diketahui masih terdapat kendala yakni keterbatasan hubungan kerja sama / MoU kelompok BKR dengan lembaga terkait, keterbatasan alat peraga dan keterbatasan kemampuan kader membuat materi penyuluhan yang menarik. Penelitian ini bertujuan untuk mendiskripsikan Implementasi Program BKR (Studi pada Kelompok BKR Mentikan II Kelurahan Mentikan Kecamatan Prajuritkulon Kota Mojokerto). Penelitian ini termasuk penelitian deskriptif kualitatif. Fokus penelitian ini yaitu ketepatan kebijakan, ketepatan pelaksanaan, ketepatan target dan ketepatan lingkungan. Subyek penelitian ini yaitu Kepala sub bidang ketahanan keluarga sejahtera dan pengarusutamaan gender kantor BKBPP Kota Mojokerto, PKB Kelurahan Mentikan, Ketua BKR Mentikan II, dan Anggota BKR Mentikan II. Hasil penelitian secara umum masih belum berhasil. Pada Indikator ketepatan kebijakan, BKKBN kurang mengatur secara terperinci mengenai MoU lembaga terkait dengan kelompok BKR sehingga menyebabkan keterbatasan layanan penyelesaian kasus anggota BKR. Pada Indikator ketepatan pelaksanaan, menunjukkan kesesuaian pelaksanaan dengan Peraturan Kepala BKKBN 109/PER/F2/2012. Sedangkan pada indikator ketepatan target, tingkat kesiapan target sasaran masih rendah. Pencapaian target sasaran hanya mencapai 57% dari total keseluruhan target. Pada kriteria ketepatan lingkungan, variabel endogen mampu menunjang dengan baik Program BKR. Namun pada variabel eksogen diketahui Program BKR tidak diuntungkan ataupun tidak dirugikan dengan adanya variabel eksogen. Kata Kunci: Implementasi Kebijakan, Program BKR, RemajaAbstract Adolescent problems become complex issues and require government studies to solve them. One of the governments responses in overcoming adolescent problems is by establishing the Youth Family Development Program (BKR) through the National Population and Family Planning Agency (BKKBN) based on the law based on the Regulation of the Head of BKKBN 109 / PER / F2 / 2012 concerning Guidelines for Management of the BKR Program. The implementation of the BKR Program at the BKR Mentikan II is known to still have constraints, namely the limited cooperation or MoU cooperation between BKR groups with related institutions, limited props and the limited ability of cadres to make interesting counseling material. This study aims to describe the Implementation of the BKR Program (Study in the BKR Mentikan II Group, Mentikan Sub District, Prajuritkulon District, Mojokerto City). This research is a qualitative descriptive study. The focus of this research is the accuracy of the policy, the accuracy of implementation, the accuracy of the target and the accuracy of the environment. The subjects of this study were the Head of Sub-Division of Prosperity in Prosperous Families and Gender Mainstreaming of the Mojokerto City BKBPP Office, PKB Kelurahan Mentikan, Chairman of BKR Mentikan II, and Members of BKR Mentikan II. Research results in general are still unsuccessful. In terms of policy accuracy, the BKKBN does not regulate in detail the relationship between the MoU of institutions related to the BKR group, which results in limited services for resolving BKR members cases. The indicator of the accuracy of the implementation shows the suitability of the implementation with the Regulation of the Head of BKKBN 109 / PER / F2 / 2012. Whereas in the target accuracy indicator, the level of target readiness is still low. Achievement of targets is only 57% of the total target. In terms of environmental accuracy, endogenous variables are able to support the BKR program well. However, in the exogenous variables it is known that the BKR Program is neither disadvantaged nor disadvantaged by the exogenous variable. Keywords: Policy Implementation, BKR Program, Adolescent

It is with great satisfaction that we present this dossier on the spatial dimensions of the crisis caused by the Covid-19 pandemic in the Latin American context. Since the first months of 2020, when it reached Latin America and the Caribbean, the pandemic has made even more explicit the great drama experienced in our continent, marked by violence and authoritarianism / patriarchy of power relations and deep socio-spatial inequality in an economy in which plunder, the processes of dispossession and extractivism prevail. The State, called to fulfill its role in matters of social policies at such a serious time, revealed its tremendous limitation, especially in the face of the neoliberal pattern that exists in most of our countries. It is under this broader panorama that the different texts presented here are displayed, which surprised us by the thematic and geographical diversity of the contributions. Papers have been received from Mexico, Colombia, Brazil and, above all, from different geographic contexts in Argentina. Together, they reveal the depth of the crisis and its multidimensional effects, where the health problem, the economic crisis, the environmental and psychological (in) order, passing through the dilemmas of political management, are just some of the topics analyzed. ; Con gran satisfacción presentamos este dossier sobre las dimensiones espaciales de la crisis provocada por la pandemia Covid-19 en el contexto latinoamericano. Desde los primeros meses de 2020, cuando llegó a América Latina y el Caribe, la pandemia ha explicitado aún más el gran drama vivido en nuestro continente, marcado por la violencia y el autoritarismo/patriarcado de las relaciones de poder y la profunda desigualdad socioespacial en una economía en la que prima el expolio, los procesos de despojo y el extractivismo. El Estado, llamado a cumplir su rol en materia de políticas sociales en un momento tan grave, reveló su tremenda limitación, sobre todo ante el patrón neoliberal que se vive en la mayoría de nuestros países. Bajo este panorama más amplio es donde se despliegan los distintos textos aquí presentados, los cuales nos sorprendieron por la diversidad temática y geográfica de las contribuciones. Se han recibido trabajos de México, Colombia, Brasil y, sobre todo, de diferentes contextos geográficos de Argentina. En conjunto, revelan la profundidad de la crisis y sus efectos multidimensionales, donde la problemática sanitaria, la crisis económica, el (des)orden ambiental y el psíquico, pasando por los dilemas de la gestión política, son sólo algunos de los tópicos analizados. ; É com grande satisfação que apresentamos este dossiê sobre as dimensões espaciais da crise provocada pela pandemia Covid-19 no contexto latino-americano. Desde os primeiros meses de 2020, quando atingiu a América Latina e o Caribe, a pandemia tornou ainda mais explícito o grande drama vivido em nosso continente, marcado pela violência e autoritarismo / patriarcado das relações de poder e profundas desigualdades socioespaciais no Brasil. uma economia em que prevalecem saques, processos de expropriação e extrativismo. O Estado, chamado a cumprir seu papel em matéria de política social em um momento tão sério, revelou sua tremenda limitação, especialmente em face do padrão neoliberal que existe na maioria de nossos países. É sob esse panorama mais amplo que se apresentam os diversos textos aqui apresentados, que nos surpreenderam pela diversidade temática e geográfica das contribuições. Recebemos artigos do México, Colômbia, Brasil e, principalmente, de diferentes contextos geográficos da Argentina. Juntos, eles revelam a profundidade da crise e seus efeitos multidimensionais, onde o problema de saúde, a crise econômica, a (des) ordem ambiental e psicológica, passando pelos dilemas da gestão política, são apenas alguns dos temas analisados.

The water has always had great importance for the populations, especially for those living in scarcity areas, where droughts are common. The dry regions are marked by physical and natural aspects that cause aridity in their landscape. This concern with water resources is growing, given the context of environmental changes. The Brazilian semiarid, where the Curimataú Paraibano is located, is the national example of dry areas. Throughout history, this region has received actions from the Brazilian State that have enabled the provision and supply of water, through water policies such as the weir, the water social technologies, exemplified by the plate cisterns, and, the focus of this research, Pipa Operation (PO). The methodology used was spatial and cartographic analysis, which used information from the Military Command of the Northeast, referring to the PO and through geotechnologies, thematic maps were created that supported the analysis. The results indicate that all municipalities in the region received the OP actions. Altogether 1.283 service points were supplied by 154 water trucks, which collected water from four water sources and used 33 main highways and 763 rural highways, serving a total of 57.482 inhabitants. ; El agua siempre ha tenido una gran importancia para las poblaciónes, especialmente para aquellos que viven en zonas de escasez, donde las sequías son comunes. Las regiones secas están marcadas por aspectos físicos y naturales que causan aridez en su paisaje. Esta preocupación por los recursos hídricos está creciendo, dado el contexto de los cambios ambientales. El semiárido brasileño, donde se encuentra el Curimataú Paraibano, es el ejemplo nacional de áreas secas. A lo largo de la historia, esta región ha recibido acciones del Estado brasileño que han permitido el suministro de agua, através de políticas de agua como la açudagem, las tecnologías sociales hídricas, ejemplificadas por las cisternas de placas y, el foco de esta investigación, la Operación Pipa (OP). La metodología utilizada fue la análisis espacial y cartográfica, que utilizó información del Comando Militar del Nordeste, refiriéndose al OP y, através de las geotecnologías, se crearon mapas temáticos que respaldaron la análisis. Los resultados obtenidos indican que todos los municipios de la región recibieron las acciones del OP. En total, 1.283 puntos de servicio fueron suministrados por 154 camiones cisterna, que recogieron agua de cuatro manantiales y utilizaron 33 carreteras principales y 763 carreteras rurales, sirviendo a un total de 57.482 habitantes. ; A água sempre apresentou grande importância para as populações, principalmente para as residentes em áreas de escassez, onde as estiagens e secas são comuns. As regiões secas são marcadas por aspectos físicos e naturais que ocasionam aridez em sua paisagem. Essa preocupação com os recursos hídricos torna-se crescente, frente ao contexto de mudanças ambientais. O Semiárido brasileiro, onde situa-se o Curimataú Paraibano, é o exemplo nacional de zonas secas. Ao longo da história, essa região tem recebido ações do Estado brasileiro que possibilitaram a disponibilização e o atendimento da oferta de água, através de políticas hídricas como a açudagem, as tecnologias sociais hídricas, exemplificadas pelas cisternas de placa, e, foco desta pesquisa, a Operação Pipa (OP). A metodologia empregada foi à análise espacial e cartográfica, o qual utilizou as informações do Comando Militar do Nordeste, referentes à OP e através das geotecnologias, foram criados mapas temáticos que subsidiaram a análise. Os resultados obtidos indicam que todos os municípios da região recebiam as ações da OP. Ao todo 1.283 pontos de atendimento eram abastecidos por 154 carros-pipa, que captavam água de quatro mananciais e utilizavam 33 rodovias principais e 763 rodovias rurais, atendendo um total de 57.482 habitantes.

It is with great satisfaction that we present this dossier on the spatial dimensions of the crisis caused by the Covid-19 pandemic in the Latin American context. Since the first months of 2020, when it reached Latin America and the Caribbean, the pandemic has made even more explicit the great drama experienced in our continent, marked by violence and authoritarianism / patriarchy of power relations and deep socio-spatial inequality in an economy in which plunder, the processes of dispossession and extractivism prevail. The State, called to fulfill its role in matters of social policies at such a serious time, revealed its tremendous limitation, especially in the face of the neoliberal pattern that exists in most of our countries. It is under this broader panorama that the different texts presented here are displayed, which surprised us by the thematic and geographical diversity of the contributions. Papers have been received from Mexico, Colombia, Brazil and, above all, from different geographic contexts in Argentina. Together, they reveal the depth of the crisis and its multidimensional effects, where the health problem, the economic crisis, the environmental and psychological (in) order, passing through the dilemmas of political management, are just some of the topics analyzed. ; Con gran satisfacción presentamos este dossier sobre las dimensiones espaciales de la crisis provocada por la pandemia Covid-19 en el contexto latinoamericano. Desde los primeros meses de 2020, cuando llegó a América Latina y el Caribe, la pandemia ha explicitado aún más el gran drama vivido en nuestro continente, marcado por la violencia y el autoritarismo/patriarcado de las relaciones de poder y la profunda desigualdad socioespacial en una economía en la que prima el expolio, los procesos de despojo y el extractivismo. El Estado, llamado a cumplir su rol en materia de políticas sociales en un momento tan grave, reveló su tremenda limitación, sobre todo ante el patrón neoliberal que se vive en la mayoría de nuestros países. Bajo este panorama más amplio es donde se despliegan los distintos textos aquí presentados, los cuales nos sorprendieron por la diversidad temática y geográfica de las contribuciones. Se han recibido trabajos de México, Colombia, Brasil y, sobre todo, de diferentes contextos geográficos de Argentina. En conjunto, revelan la profundidad de la crisis y sus efectos multidimensionales, donde la problemática sanitaria, la crisis económica, el (des)orden ambiental y el psíquico, pasando por los dilemas de la gestión política, son sólo algunos de los tópicos analizados. ; É com grande satisfação que apresentamos este dossiê sobre as dimensões espaciais da crise provocada pela pandemia Covid-19 no contexto latino-americano. Desde os primeiros meses de 2020, quando atingiu a América Latina e o Caribe, a pandemia tornou ainda mais explícito o grande drama vivido em nosso continente, marcado pela violência e autoritarismo / patriarcado das relações de poder e profundas desigualdades socioespaciais no Brasil. uma economia em que prevalecem saques, processos de expropriação e extrativismo. O Estado, chamado a cumprir seu papel em matéria de política social em um momento tão sério, revelou sua tremenda limitação, especialmente em face do padrão neoliberal que existe na maioria de nossos países. É sob esse panorama mais amplo que se apresentam os diversos textos aqui apresentados, que nos surpreenderam pela diversidade temática e geográfica das contribuições. Recebemos artigos do México, Colômbia, Brasil e, principalmente, de diferentes contextos geográficos da Argentina. Juntos, eles revelam a profundidade da crise e seus efeitos multidimensionais, onde o problema de saúde, a crise econômica, a (des) ordem ambiental e psicológica, passando pelos dilemas da gestão política, são apenas alguns dos temas analisados.

New dwellings or deeply renovated existing dwellings are designed to be energy efficient, and have airtight structures. This leads to a risk of high indoor pollutant loads due to activities and emissions from materials in contact with indoor air. Ventilation must be dosed at the right volume of clean air, efficiently distributed in the occupant zone and with proper scheduling in order to keep indoor pollutant concentrations low, while not increasing the energy need. Building designers, contractors, owners and operators, and decision makers need the newest knowledge on how to operate ventilation to achieve this. The project has focused on new and existing residential buildings, although it should be underlined that many findings may also be relevant to other building types. At the onset of the project, the existing indicators for indoor air quality (IAQ) were reviewed and indicators were defined that would specifically facilitate the other subtasks in this project. The IAQ indicators to be studied were documented in a report, which collected state of the art information and suggested a principle in the form of a "dashboard" on how to balance the combination of the most significant among many pollutants to be considered. The dashboard also highlighted the energy performance aspect. A main result of the project is an easy to understand and practically applicable collection of experiences with design and operational strategies to achieve optimal energy performance and high IAQ in residential buildings. The collection is intended for those involved in the construction and maintenance of buildings. Furthermore, the project presents a modelling framework and design tools, suitable for integrated and coordinated design of buildings with low energy consumption and high IAQ. With regards to pollutants in buildings, data and models have been applied on sources and sinks of pollutant emissions to estimate the net pollutant loads over time under realistic environmental conditions. This is supported by databases on the properties of materials with respect to pollutant emissions. Finally, field tests and case studies were documented for different climatic zones as well as methodologies to carry out such testing. Specifically, this activity targeted industry partners, building owners and operators. The project was carried out with contributions from researchers from some 39 research institutions from 15 countries worldwide, while one participant was a global enterprise that supplies building products and solutions in many areas. Several local stakeholders such as consultants and HVAC manufacturers and associations have been visitors to the project when expert meetings were held semi-annually in different countries. Meetings were usually planned to be held in conjunction with relevant conferences such as by AIVC, ASHRAE but also Indoor Air, IBPC and IAQVEC conferences. The project has also fostered input to meetings in the interest group "CHAMPS" on Combined Heat, Air, Moisture and Pollutant Simulation, which convenes annually in different places of the world. An important lead from the project to policy makers is to facilitate possibility by legislation that residential buildings may be operated flexibly and intelligently with regards to demand control of building ventilation in a manner that considers realistic hygrothermal and pollutants loads in buildings. Furthermore, the project has highlighted the need for more quality management since traditional and novel mechanical ventilation concepts as presented in this project all have in common that quality assurance during design, construction and operation is crucial for success, i.e. high IAQ and comfort while minimizing energy use. Consequently, a framework for quality assurance and inspection is needed.

Reduced function of the serotonin transporter (SERT) is associated with increased susceptibility to anxiety and depression and with type-2 diabetes, which is especially true in older women. Preference for a "Western diet" (WD), enriched with saturated fat, cholesterol, and sugars, may aggravate these conditions. In previous studies, decreased glucose tolerance, central and peripheral inflammation, dyslipidemia, emotional, cognitive, and social abnormalities were reported in WD-fed young female mice. We investigated the metabolic, molecular, and behavioral changes associated with a 3-week-long dietary regime of either the WD or control diet in 12-month-old female mice with three different Sert genotypes: homozygous (Slc6a4) gene knockout (Sert−/−: KO), heterozygous (Sert+/−: HET), or wild-type mice (Sert+/+: WT). In the WT-WD and KO-WD groups, but not in HET-WD-fed mice, most of changes induced by the WD paralleled those found in the younger mice, including brain overexpression of inflammatory marker Toll-like receptor 4 (Tlr4) and impaired hippocampus-dependent performance in the marble test. However, the 12-month-old female mice became obese. Control diet KO mice exhibited impaired hippocampal-dependent behaviors, increased brain expression of the serotonin receptors Htr2c and Htr1b, as well as increased Tlr4 and mitochondrial regulator, peroxisome proliferator-activated receptor gamma-coactivator-1a (Ppargc1a). Paradoxically, these, and other changes, were reversed in KO-WD mutants, suggesting a complex interplay between Sert deficiency and metabolic factors as well as potential compensatory molecular mechanisms that might be disrupted by the WD exposure. Most, but not all, of the changes in gene expression in the brain and liver of KO mice were not exhibited by the HET mice fed with either diet. Some of the WD-induced changes were similar in the KO-WD and HET-WD-fed mice, but the latter displayed a "rescued" phenotype in terms of diet-induced abnormalities in glucose tolerance, neuroinflammation, and hippocampus-dependent performance. Thus, complete versus partial Sert inactivation in aged mice results in distinct metabolic, molecular, and behavioral consequences in response to the WD. Our findings show that Sert+/− mice are resilient to certain environmental challenges and support the concept of heterosis as evolutionary adaptive mechanism. © Copyright © 2020 Veniaminova, Cespuglio, Chernukha, Schmitt-Boehrer, Morozov, Kalueff, Kuznetsova, Anthony, Lesch and Strekalova. ; 01EW1602B, 01EW1902, 602805 ; Deutsche Forschungsgemeinschaft, DFG: CRC TRR 58 A1/A5 ; Horizon 2020 Framework Programme, H2020: Eat2beNICE, 728018, 643051 ; Russian Science Foundation, RSF: 16-16-10073 ; Seventh Framework Programme, FP7 ; I.M. Sechenov First Moscow State Medical University, MSMU ; Deutsche Forschungsgemeinschaft, DFG ; We thank Collette Rousset and Donia Amrouni from C. Bernard University, Anna Gorlova from Sechenov University, and Anastasiya Kibitkina and Galina Tolmacheva from the Gorbatov Research Center for their valuable contribution to this work. Funding. The authors? work reported here was supported by the Deutsche Forschungsgemeinschaft (DFG: CRC TRR 58 A1/A5), the European Union?s Seventh Framework Programme (FP7/2007?2013) under Grant No. 602805 (Aggressotype), ERA-Net NEURON/RESPOND, No. 01EW1602B and ERA-Net NEURON/DECODE, No. 01EW1902 (to K-PL), the Horizon 2020 Research and Innovation Programme under Grant No. 728018 (Eat2beNICE) and Grant No. 643051 (MiND), 5-100 Russian Academic Excellence Project (to K-PL and TS), the Russian Science Foundation (RSF) Project No. 16-16-10073 (to IC and OK), and the University of W?rzburg in the funding programme Open Access Publishing (to KP-L).

The statistics have been assigned the factors of politics (political and legal, policy, social, environmental and global) and internal relations (organizational and economic personnel). On the basis of the recognized requirements and the internal potential functions, the power supply and the power industry, a number of macro-economic and non-technical changes are violated, which are directly related to the lack of safety and security. It has been reinstated, right now, that realizatsion of economical influx on macro may: concentrate on the key aspects of stream problems of electricity generation for the consolidation of system interconnections; include the selection of specialized strategies and the program for developing galactic products in all regions of the region; transfer of investment, investment and innovation processes, as well as a lot of warehouse structural policy; base on the demonopolization of the national energy market and the transition to the most advanced models of functional functions. Prior to direct management of energy efficiency, the following information was presented: detailed plans for innovative development plans, modernization, modernization, and economic knowledge; the establishment of a system for operational monitoring of key indicators of efficiency and effectiveness of electric energy; victorious investment components at the post-warehouse warehouse of the system of value; analysis of foreign gospodar practices, ix of experience in the framework of a specific initiative and the progressive transition to European energy standards. ; В статье определены факторы внешних (политико-правовые, конъюнктурные, социальные, экологические и глобализационные) и внутренних рисков (организационно-экономические, производственные и кадровые) деятельности предприятий электроэнергетики. На основе определенных внешних и внутренних потенциальных рисков функционирования предприятий электроэнергетики выделены ряд мер макроэкономического и микроэкономического характера, направленных на обеспечение качественной трансформации отечественных предприятий энергетической отрасли, в направлении обеспечения их устойчивого развития. Установлено, что направления реализации мер экономического воздействия на макроуровне имеют: сконцентрироваться на ключевых аспектах текущей проблематике отечественной электроэнергетики для устранения системных ограничений развития; включать в себя разработку профильных стратегий и программ развития предприятий отрасли на всех уровнях исполнительной власти; предусматривать интенсификацию инвестиционно-инновационных процессов как неотъемлемой составляющей структурной политики; базироваться на демонополизации национального энергорынка и перехода к более современных моделей его функционирования. К направлений совершенствования управленческой деятельности предприятий электроэнергетики отнесены: разработку конкретных планов инновационного развития предприятия, нацеленных на модернизацию, реновацию и экологизацию физически и морально устаревшего оборудования; создание системы оперативного мониторинга ключевых показателей эффективности деятельности электроэнергетических предприятий; использования инвестиционной компоненты в качестве постоянного компонента системы ценообразования; анализ зарубежных хозяйственных практик, их качественная имплементация в рамках конкретного предприятия и постепенный переход к европейским энергетическим стандартам. ; У статті визначено фактори зовнішніх (політико-правові, кон'юнктурні, соціальні, екологічні та глобалізаційні) та внутрішніх ризиків (організаційно-економічні, виробничі та кадрові) діяльності підприємств електроенергетики. На основі визначених зовнішніх та внутрішніх потенційних ризиків функціонування підприємств електроенергетики виокремлено ряд заходів макроекономічного та мікроекономічного характеру, спрямованих на забезпечення якісної трансформації вітчизняних підприємств енергетичної галузі, у напрямку забезпечення їх сталого розвитку. Встановлено, що напрямки реалізації заходів економічного впливу на макрорівні мають: концентруватися на ключових аспектах поточної проблематики вітчизняної електроенергетики задля усунення системних обмежень розвитку; включати в себе розробку профільних стратегій та програм розвитку підприємств галузі на всіх рівнях виконавчої влади; передбачати інтенсифікацію інвестиційно-інноваційних процесів як невід'ємної складової структурної політики; базуватися на демонополізації національного енергоринку та переходу до більш сучасних моделей його функціонування. До напрямків вдосконалення управлінської діяльності підприємств електроенергетики віднесено: розробку конкретних планів інноваційного розвитку підприємства, націлених на модернізацію, реновацію та екологізацію фізично та морально застарілого обладнання; створення системи оперативного моніторингу ключових показників ефективності діяльності електроенергетичних підприємств; використання інвестиційної компоненти у якості постійного складника системи ціноутворення; аналіз зарубіжних господарських практик, їх якісна імплементація у рамках конкретного підприємства та поступовий перехід до європейських енергетичних стандартів.

Reducing the energy consumption in the building sector, as well as its associated CO2 emissions, is one of the main environmental concerns at worldwide level. In developed countries, the building sector means 41% of the total energy consumption and 40% of the total greenhouse gases emissions. To improve the energy efficiency of residential buildings, several energy strategies were carried out in European countries to encourage the development of active energy saving systems; such as the solar thermal energy. The presented study is in the frame of the Innova MicroSolar European project, which is sponsored by the European Union's Horizon 2020 research and innovation programme. The main goal of this project is to develop an innovative concentrated solar heat and power system for residential buildings, which supplies 2-kWelec and 18-kWth. This technology includes a concentrated solar system, a high performance micro organic Rankine cycle (ORC) turbine, and an enhanced latent heat thermal energy storage (LHTES). The solar system is based on linear Fresnel mirrors which are considerably easier and cheaper to manufacture than their parabolic equals. Also, the mirrors are led by a sun tracking mechanism so they are always focusing the absorber tubes, heating up to 295ºC the heat transfer fluid (HTF) flow. The total area of the real scale prototype solar field is 140 square metres, which could provide from 80 to 15 kWth. The micro ORC technology is equipped with a high speed permanent magnet AC alternator able to supply 2.3 kWel. The ORC block has to be fed with 22 kWth. Finally, the TES tank consists of two main blocks, the PCM tank and the enhanced heat sink. Both blocks are connected between them by reversible heat pipes as heat carrier. The storage is designed to supply 25 kWth during four working hours. The whole system will supply 60% of the total building energy demand, reducing the energy cost up to 20%, as well as the greenhouse gases emissions when comparing against the best renewable energy technologies available on the market. This study shows the first experiments of the whole systems. The HTF (Therminol 62) is heated up to 270ºC with the solar field, then the HTF is lead to the ORC evaporator and the organic fluid (cyclopenthane) evaporates and runs the turbine. The TES tank is charged when the solar field reaches maximum power levels. Once the solar production cannot run the ORC, the solar field is bypassed and the TES tank successfully becomes the main energy supplier. ; The research leading to these results has received funding from the European Union´s Horizon 2020 Research & Innovation Programme under Grant Agreement 723596 with reference name Innova MicroSolar. This work was partially funded by Spanish government (ENE2015-64117-C5-1-R (MINECO/FEDER)). José Miguel Maldonado would like to thank the Spanish Government for his research fellowship (BES-2016-076554). Alvaro de Gracia has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 712949 (TECNIOspring PLUS) and from the Agency for Business Competitiveness of the Government of Catalonia. The authors would like to thank the Catalan Government for the quality accreditation given to their research group GREiA (2017 SGR 1537). GREiA is a certified agent TECNIO in the category of technology developers from the Government of Catalonia.

Il presente lavoro di tesi è il risultato di tre anni di studio realizzato in collaborazione con l'Osservatorio regionale energia della Regione Emilia-Romagna. Il progetto di ricerca è nato dalla necessità di indagare le motivazioni che hanno portato al picco dei consumi energetici, tre anni prima della crisi economica che ha colpito le economie globali. Lo studio, incentrato sull'analisi delle relazioni tra indicatori energetici ed economici, ha dapprima analizzato la principale letteratura sull'argomento. Tale analisi ha messo in luce come dai primi studi risalenti agli anni '70, le metodologie statistiche ed econometriche che tentavano di individuare una direzione di causalità tra consumi energetici e crescita economica siano diventate sempre più complesse. Tali studi però non hanno fornito risultati univoci. Sono stati quindi messi a punto gli strumenti utili per l'analisi di queste relazioni, a partire dai bilanci energetici e dalle matrici di contabilità ambientale (NAMEA) a scala regionale. I primi forniscono i principali indicatori energetici, le seconde gli indici economici integrati con diversi indicatori di sviluppo sostenibile. Dopo l'analisi delle intensità energetiche a diversa scala territoriale (europea, nazionale e regionale), ci si è concentrati sulla valutazione del disaccoppiamento tra indicatori di consumo ed indicatori economici. Infine si sono messe a punto metodologie semplificate di previsione dei consumi, focalizzandosi sul settore industriale della Regione Emilia-Romagna. I risultati delle modellistiche applicate provano come in Emilia-Romagna dopo due forti fasi recessive, il settore industriale rappresenti il motore dell'economia regionale. Le analisi per la previsione dei consumi a breve termine mostrano una ripresa dei consumi industriali ed in particolare dei consumi di gas naturale e dei consumi di elettricità. Le analisi di disaccoppiamento hanno evidenziato come il settore industriale Emiliano-Romagnolo abbia risposto in modo positivo alle politiche di efficienza energetica poste in essere dal settore manifatturiero, soprattutto dal 2007 in poi. ; This thesis is the result of a three years' research carried out in collaboration with the Regional Energy Observatory of the Emilia-Romagna Region. The idea of the research was born while investigating the reasons that led to the peak of energy consumption, three years before the economic crisis that hit global economies. The study, focusing on analyzing the relationships between energy and economic indicators, first analyzed the main literature on the subject. This analysis has highlighted that, since the first studies dating back to the '70s, the statistical and econometric methodologies that attempted to identify a causal direction between energy consumption and economic growth have become increasingly complex. However, these studies did not provide univocal results. New tools, useful for the analysis of these relationships, were then developed, starting from the energy balances and the environmental accounting matrices (NAMEA) on a regional scale. The former provide the main energy indicators, the latter the economic indicators integrated with various indicators of sustainable development. After analyzing the energy intensities at different territorial scales (European, national and regional), an assessment of the decoupling between energy consumption indicators and economic indicators were analyzed. Finally, simplified methodologies aiming at forecasting energy consumption were developed, focusing on the industrial sector of the Emilia-Romagna Region. Decoupling analysis have shown that the Emilia-Romagna industrial sector has responded positively to the energy efficiency policies implemented by the manufacturing sector, especially from 2007 onwards. The results of the applied models have proved that in Emilia-Romagna, after two strong recessionary phases, the industrial sector still represents the engine of the regional economy. Moreover, the analyzes of short-term energy consumption forecasts show a recovery in industrial consumption and in particular in the consumption of natural gas and electricity consumption.

The natural and social environmental impacts of the expansion of palm oil plantation companies have invited many protests from the local communities and local NGOS. The many consequences of this expansion have been documented to include increasingly the deforesation and conversion of forest areas. Then invites polemic and conflict between oil palm plantation companies and local communities. In this study took place in Batu Daya village of Ketapang Regency, where indigenous peoples and local communities who have settled hereditary and actively use the forest for daily needs and make a living, according to indigenous knowledge and traditions. They must participate in the games of palm oil companies in the management of their private land. This research uses qualitative methods with ethnographic approaches, where the analysis of conflicts as data analysis. The data used is primary data through interviews and observations in the field, then secondary data comes from village government documents, corporate documents, government regulations and scientific journals. The findings of this research is a communal conflict that occurred between the Palm Plantation company PT. Swadaya Mukti Prakarsa initiative with the community in Batu Daya Village, due to changes in the socio-economic structure of the community traditional landscape on the potential of natural wealth to the capitalist system through the core and plasma patterns. Then, the process of communal conflict between palm plantation company PT. Swadaya Mukti Prakasa with the people of Batu Daya village as a result of the society felt not to get enlightened life as hope. The communal conflict between the palm Plantation company PT. Swadaya Mukti Prakasa initiative with the people of Batu Daya village has actually been mediated by local NGO's in West Kalimantan. Keywords: Conflict; Palm Oil; Company; Customary Community Abstrak Terjadinya dampak lingkungan alam dan sosial dari ekspansi perusahaan perkebunan kelapa sawit banyak mengundang protes dari masyarakat, komunitas lokal dan LSM lokal. Banyaknya akibat dari ekspansi ini berhasil didokumentasikan meliputi deforesasi yang semakin merajalela dan konversi wilayah hutan yang luas. Hal ini kemudian mengundang polemik dan konflik antara perusahaan perkebunan sawit dengan masyarakat lokal. Pada penelitian ini mengambil lokasi di Desa Batu Daya Kabupaten Ketapang, dimana masyarakat adat dan komunitas lokal yang telah menetap secara turun-temurun dan secara aktif menggunakan hutan untuk kebutuhan sehari-hari dan mencari nafkah, sesuai dengan pengetahuan dan tradisi adat. Mereka harus ikut ke dalam permainan perusahaan kelapa sawit dalam pengelolaan lahan milik pribadi. Penelitian ini menggunakan metode kualitatif dengan pendekatan etnografi, dimana analisis konflik sebagai pisau analisa data. Data yang digunakan adalah data primer melalui wawancara dan observasi di lapangan, kemudian data sekunder berasal dari dokumen pemerintahan desa, dokumen perusahaan, peraturan pemerintah dan jurnal ilmiah. Temuan penelitian ini yaitu konflik komunal yang terjadi antara Perusahaan Perkebunan Sawit PT. Swadaya Mukti Prakarsa dengan masyarakat di Desa Batu Daya, disebabkan perubahan struktur sosial-ekonomi masyarakat dari sistem peladangan tradisional atas potensi kekayaan alam ke sistem kapitalis melalui pola inti dan plasma. Kemudian, proses konflik komunal antara Perusahaan Perkebunan Sawit PT. Swadaya Mukti Prakarsa dengan masyarakat Desa Batu Daya sebagai akibat dari masyarakat merasa tidak mendapatkan pencerahan hidup sebagaimana harapan (untung-rugi yang tidak jelas). Konflik komunal antara Perusahaan Perkebunan Sawit PT. Swadaya Mukti Prakarsa dengan masyarakat Desa Batu Daya sebenarnya telah ditengahi oleh berbagai LSM lokal di Kalbar. Kata Kunci: Konflik; Kelapa Sawit; Perusahaan; Adat

Il dibattito sul consumo della carne è molto attuale e viene spesso associato alla sostenibilità ambientale, ma anche economica e sociale, coinvolge numerose materie e attori differenti. Per questo motivo è difficile dare una definitiva ed esaustiva visione di questo contesto. Questo progetto di tesi vuole illustrare il dibattito sul tema del consumo della carne in relazione alla salubrità della dieta, con riferimento al conteso italiano. Si analizzano le differenti posizioni sulla questione dei principali attori coinvolti, dal settore della nutrizione, alla filiera della carne, all'ambito istituzionale, quali il Ministero della Salute e il Ministero delle Politiche Agricole, Alimentari, Forestali, il Ministero per l'Ambiente ed il Ministero dell'Istruzione Ministero dell'Università e della Ricerca. Verranno indentificate le modalità di comunicazione utilizzate per inquadrare e direzionare il consumatore verso uno stile di vita sano, che comprenda il consumo della carne o altre scelte alternative. Sono stati interpellati esperti di settore, che quotidianamente lavorano e affrontano le difficoltà legate al contesto della carne, provenienti dal mondo accademico, dalla zootecnia, fra i nutrizionisti, dalla ristorazione collettiva, dalla Grande Distribuzione, dalla società civile, per illustrare la loro posizione sul dibattito del ruolo della carne nell'alimentazione, gli strumenti e le difficoltà che incontrano nella comunicazione con il consumatore e quali siano le possibili prospettive future. Il loro apporto, elaborato nel quarto capitolo, permette di identificare le raccomandazioni alimentari e nutrizionali che vengono indicate al consumatore e di indagare sulle motivazioni che spingono anche attori non statali alla divulgazione di notizie su questa tematica. Si conclude con una panoramica e elaborazione dei dati raccolti e la situazione del sistema alimentare attuale, nello specifico della carne. Debate on meat consumption and healthy diet: perspective from stakeholders involved in the Italian food system. The discussion on meat consumption is really current and often associated with environmental, economical and social sustainability. However, a broad range of subjects and actors are involved in the field. As a consequence, to give a definitive and exhaustive vision has become more and more difficult. This thesis aims to illustrate the debate on the issue of meat consumption in relation to the healthiness of the diet, specifically applied to the Italian case/context. The project analyses the views of the different actors involved, from the nutrition sector to the meat chain, to the institutional sphere, such as the Ministry of Health and the Ministry of Agriculture, Food, Forestry, the Ministry for the Environment and the Ministry of Education Ministry of University and Research. Furthermore, the object of the study will be communication methods used to frame and direct the consumer towards healthier lifestyle, which might include either the consumption of meat or other alternative choices. Experts of the sector were interviewed due to their daily interactions with to the meat context, from the academic world, from zootechnics sector, from nutritionists, from collective catering, from large-scale distribution, from civil society. The aim of this action was to illustrate their position regarding this debate on the role of meat in nutrition, as well to present their tools and difficulties when communicating with the consumer. Finally, their participation was fundamental when discussing future prospects. Their contribution, elaborated in the fourth chapter, enables the identification of the consumers' dietary and nutritional recommendations and to investigate the reasons for non-state actors to disseminate news on this issue. The thesis ends with an overview and processing of the data collected and the situation of the current food system, with a specific focus on the meat.

Grâce au partenariat Tradition and Transition among Labrador Inuit unissant le Gouvernement Nunatsiavut et l'Université Mémorial de Terre-Neuve, la fouille exhaustive du site Double Mer Point (GbBo-02) a pu être effectuée. Elle nous a permis d'étudier l'impact des interactions culturelles au Labrador sur la vie quotidienne des occupants de l'Habitation 1 durant la période de contact, soit entre XVIIe et le XIXe siècle; un sujet d'étude encore sous-exploité par l'archéologie. Des idées théoriques tirées des Cultural Contact Studies et de l'archéologie postcoloniale ont ainsi pu être appliquées au cadre contextuel du Labrador par la réalisation de ce mémoire. Notre réflexion théorique portant sur l'étude des assemblages de la période de contact nous a mené à développer une méthodologie de recherche combinant l'aspect culturel d'un objet et son mode de fabrication. L'Habitation 1, une maison semi-souterraine en tourbe datée entre la fin du XVIIIe siècle et le début du XIXe siècle, a pu être interprétée à partir des données (matérielles, zooarchéologiques, architecturales et environnementales) collectées lors des fouilles en 2015. La datation du site, les phases d'occupation et les aires d'activités ont été déterminées grâce à diverses analyses. L'Habitation 1 a dévoilé une occupation plus complexe que la plupart des maisons semi-souterraines de cette période. Elle a témoigné de plusieurs phases d'occupation dont la première serait dorsétienne, tandis que la dernière démontre l'intégration d'un Européen à une communauté inuite. L'application de la méthodologie développée a quant à elle permis d'identifier des transferts culturels directs, d'observer l'intensification de traits culturels intrinsèques, d'étudier l'influence d'une nouvelle matière sur le quotidien d'une communauté et d'évaluer l'impact de ces changements à long terme. Ce mémoire participe à la reconstitution de l'histoire culturelle du Labrador et espère encourager la réalisation de recherches portant sur les interactions culturelles et l'étude de la culture matérielle de la période de contact. ; Through the Tradition and Transition among Labrador Inuit partnership between the Nunatsiavut Government and the Memorial University of Newfoundland, the extensive archaeological excavation undertaken at Double Mer Point (GbBo-02) allowed us to study the impact of cultural interactions in Labrador on the daily life of the inhabitants of House 1 during the contact period, between the 17th and 19th centuries, a subject still under-exploited by archeology. Theoretical ideas from cultural contact studies and postcolonial archeology have thus been applied to Labrador through this research. Our theoretical reflection about the study of material culture from the contact period led to the development of a methodology combining the cultural aspects of objects and their manufacture. House 1, a semi-subterranean sod house dated from the late 18th and early 19th century, was interpreted using data (material, zooarchaeological, architectural and environmental) collected directly in the field. The dating of the site, the occupation phases and activities areas were determined via various analyzes. House 1 revealed a more complex occupation than most of the semi-subterranean houses of this period. It suggests of several phases of occupation of which the first would be a prehistoric Dorset occupation while the last one demonstrates the integration of a European in an Inuit community. The application of our methodology allows us to identify direct cultural transfers, to observe the intensification of intrinsic cultural traits, to study the influence of new material in the daily life of a community and to assess the impact of these changes in Labrador. This thesis contributes to the reconstruction of the cultural history of Labrador and hopes to encourage research about cultural interactions and material culture of the contact period.

peer-reviewed ; his article belongs to the Proceedings of TERRAenVISION 2019 ; Our planet suffers from humankind's impact on natural resources, biogeochemical cycles and ecosystems. Intensive modern agriculture with inappropriate inputs of fertilisers, pesticides and fossil fuel –based energy has increasingly added to human pressure on the environment. As a key element of our natural capital, soils are also under threat, despite being essential to provide food, feed, fibre and fuel for an increasing global population. Moreover, soils play a key role in carbon, water and energy cycles, highlighting their importance for biomass provision and the circular bioeconomy. Evidently, these new and complex challenges cannot be resolved effectively with existing knowledge and experience alone. These challenges require scientific research, interdisciplinary collaboration and networking to find context-specific and tailored solutions addressing societal issues of our time and facilitating the adoption of these solutions. The most effective approaches are based on the involvement of multiple actors from science, policy, economy, civil society and farming that have the same goal, work on the same societal issue, but have complementing backgrounds, expertise and perceptions. The European Joint Programme (EJP) SOIL is a European network of research institutes in the field of soil science and agricultural soil management that will provide science-based advice to practitioners and policymakers, at local, national and European level. The EJP SOIL aims to align and boost research, training and capacity building through joint programming activities co-funded by the European Commission and national research programs. This will reduce current fragmentation and help to find synergies in order to make a leapfrog in research on good agricultural soil management in three main areas: climate change mitigation and adaptation, production capacity in healthy food systems, and environmental sustainability. By joint programming, training and capacity building, EJP SOIL will also take into account the need for effective policy solutions, as well as the socio-economic conditions of all stakeholders in the agricultural value chain. Thus, a key focus of the EJP SOIL is to build and strengthen a framework for an integrated community of research groups working on related aspects of agricultural soil management. As part of this effort, EJP SOIL will co-construct with stakeholders a roadmap for agricultural soil research. To develop a structured roadmap, EJP SOIL works with a version of the knowledge management framework of Dalkir (2005). The EJP version uses four compartments: (i) Knowledge development, (ii) knowledge harmonisation, organisation and storage (iii) knowledge sharing and transfer, and (iv) knowledge application. The four segments are part of a cyclic process to enhance the development and use of knowledge on agricultural soils. Knowledge development comprises assessing new knowledge needs to achieve the expected impacts of EJP SOIL. Therefore, by involving multiple stakeholders, knowledge gaps across Europe will be identified to work towards the adoption of Climate-Smart Sustainable Agricultural Soil Management (CSSASM). Within the knowledge sharing and transfer compartment, the capacity of scientists, advisors, policy makers, farmers and other stakeholders will be strengthened. EJP SOIL will work to support networks and co-creation of new knowledge with stakeholder groups, stimulating innovation in CSSASM. The knowledge harmonization, organization and storage compartment of the knowledge framework ensures linkages with all stakeholders to guarantee data harmonization and standardization. The last compartment, application of knowledge, will be facilitated by creating better guidelines, awareness and capacity for Climate-Smart Sustainable Agricultural Soil Management adoption and by strengthening science-to-policy processes at EU and Member State level.