Suchergebnisse

Las Tecnologías de la información y la comunicación en el sector educativo tienen una relevancia importante en el proceso de enseñanza aprendizaje de los estudiantes y en el conocimiento de las competencias para la vida. El objetivo de la investigación fue analizar el uso de las TIC como herramientas de aprendizaje ante la contingencia COVID-19 en los alumnos de la Facultad de Contaduría y Administración de la Universidad Autónoma de Chihuahua en México. La naturaleza de esta investigación fue cuantitativa y el tipo de investigación fue de forma aplicada, el alcance fue descriptivo y la investigación de campo, el diseño fue no experimental transeccional descriptivo, la técnica de recolección de información fue mediante un cuestionario. Los resultados revelaron una correlación positiva hacia las tecnologías de información y comunicación, que se evidencia en diferentes aspectos examinados: estilo de aprendizaje, dominio en el uso de las TIC, redes sociales, programa educativo, nivel de satisfacción de contar con los recursos tecnológicos apropiados, entre otras; en todas ellas se manifiesta una predisposición favorable. Las ventajas que los estudiantes consideran con el uso de las TIC son la disponibilidad de información y aprendizaje colaborativo. De las desventajas que se identificaron fueron las fallas en la conexión de Internet, tienen acceso a muchas distracciones durante la clase y consideran que tienen un menor aprendizaje. Uno de los hallazgos más importantes de esta investigación fue que los estudiantes tienen muy buen dominio de las TIC para manejar las herramientas tecnológicas utilizadas durante la contingencia sanitaria del COVID-19.

Como en cualquier industria, en la manufactura refresquera la demanda, servicio al cliente y producción tien e una gran importancia lo que obliga a esta producción a tener sus equipos y maquinaria de producción en óptimas condiciones para que el producto esté en manos del consumidor sin retrasos, por lo tanto, es importante tener los tiempos establecidos de cada proceso, desde que es elaborado el jarabe, envasado, distribuido, hasta que es comprado por el consumidor. Después de un análisis de cronómetro se conocen las fallas más comunes en cada proceso analizado. En máquina llenadora las fallas más frecuentes son: acumulación de botellas en los procesos posteriores y anteriores a llenadora, que por lo general la causa del acumulamiento de botellas es por fallas en los demás equipos de la línea de producción. En el proceso de desestibado las fallas más comunes son: cajas atoradas en tope volteador y en arreador (empuje de cajas); cajas caídas en rodillos y transportador de tarimas. De acuerdo a lo observado en cada máquina, se plantean las acciones a seguir para dar solución a los problemas que surgen . Se presenta la descripción de la metodología que se sigue para obtener resultados, analizarlos y tomar decisiones. Primeramente se hace un análisis de operaciones para conocer cada máquina, apoyado de los manuales de máquinas y los propios operadores, se realiza un es tudio de tiempos con cronómetro para determinar el tiempo estándar del proceso, donde también se presentan las fallas más comunes, posteriormente se realizan observaciones en las máquinas según el tamaño de muestra determinado, obteniendo así la informaci ón necesaria para tomar medidas y hacer el estudio de optimización de los procesos de producción. Se realiza también un análisis de los tiempos predeterminados del proceso mediante los métodos de MTM y análisis de tiempos MOST. Los resultados de operadores con MTM son: Llenadora con fallas = 0.846 minutos, Llenadora sin fallas = 0.61 minutos, Desestibadora con fallas = 0.74 minutos y Desestibadora sin fallas = 0.45 minutos. Los resultados de operadores con MOST son: Llenadora con fallas = 2.58 minutos , L lenadora sin fallas = 2.35 minutos, Desestibadora con fallas = 2.15 minutos, Desestibadora sin fallas = 1.68 minutos. Se concluye que el análisis de tiempo es una herramienta adecuada para determinar el tiempo de los procesos y hacer las recomendaciones de mejora, para minimizar o evitar el tiempo perdido y optimizar las condiciones de operación en el proceso.

Summary This article presents a study aimed at comparing the perceptions of a group of students about their ICT competences with those of their teachers. The students taking part belong to the online degree at the Faculty of Contaduría and Administration of the Autonomous University of Chihuahua. The measuring instrument comprised six types of competences: basic, implementation, deepening, teamwork, lifelong learning and ethics. Methodological, it was raised as a quantitative case study; it was developed by analytical, synthetic and theoretical deductive procedures. The results include the disparity between student and teacher assessments, with the tendency of the former to assign higher assessments than those assigned by teachers, even in complex competences. The survey shows that learners, while having basic digital skills, need to be strengthened in terms of implementation and deepening, which refer to the use of scientific information bases, analysis, collective work and ethical awareness. ; Resumen Este artículo expone un estudio cuyo objetivo fue cotejar las percepciones de un grupo de estudiantes sobre las competencias que tienen en tecnologías de información y comunicación con las de sus docentes. Los alumnos participantes pertenecen a la licenciatura en línea de la Facultad de Contaduría y Administración de la Universidad Autónoma de Chihuahua. El instrumento de medición comprendió seis tipos de competencias: básicas, de aplicación, profundización, trabajo en equipo, aprendizaje permanente y éticas. Metodológicamente, se planteó como un estudio de caso, cuantitativo; se desarrolló por procedimientos analítico-sintético y teórico-deductivo. Entre los resultados destaca la disparidad entre las valoraciones de estudiantes y docentes, con la tendencia de los primeros a asignarse evaluaciones superiores a las asignadas por los maestros, aun en competencias complejas. La indagación muestra que los alumnos, aunque tienen competencias digitales básicas, requieren reforzar las de aplicación y profundización, que ...

The benefits of e-government services depend on the number of citizens who take advantage of them. The purpose of this quantitative, correlational research study was to determine barriers to e-government use as perceived by citizens at the municipal level in Mexico. The technology acceptance model (TAM), the diffusion of innovations (DOI) theory, and models of web trust formed the theoretical framework of the study. Several hypotheses tested the relation of demographic variables, TAM, DOI, and web trust constructs to the intention of using e-government services of 149 taxpayers of the city of Chihuahua, Mexico, who did not to use the e-government services for payment provided by the government of their municipality. The findings of this study show that trust in the Internet, trust in government, perceptions of convenience, perceptions of compatibility, access to the Internet, perceptions of ease of use, and perceptions of relative advantages are related to the intention to use e-government services. Conversely, awareness of the existence of e-government services, income level, family structure, age, literacy level, computer literacy level, gender, and possession of bankcards are not individually related to the intention to use e-government services of those persons who made face-to-face payments at the treasury office.

The current challenge of agriculture is to ensure sustainability, noting that in the next half century we must produce as much food as in the previous ten thousand years combined. At the same time, we should improve crop resilience, in an unquestionable scenario of climate change. The World Food and Agriculture Organization (FAO) urges us to achieve food security, which is the situation in which everybody has physical and economic access to sufficient, safe nutritious food at all times, to satisfy their nutritional needs and preferences, in order to lead an active and healthy life. In recent years we have seen an exponential increase in the knowledge of the molecular basis of genetic traits that are important for food production. Some of these technologies have been developed in Europe, and benefit producers from other parts of the world, from whom our countries then import their products for our consumption. It has been possible to increase the micronutrient content of fruit, delay their ripening or incorporate resistance to viruses, fungi and bacteria. Thus, using tools borrowed from bacterial defence mechanisms (CRISPR-Cas9 and derivatives), it is possible to act in a controlled and timely manner on the desired areas of DNA (Deoxyribonucleic Acid), as could be the case in the fight against TR4 fungus in the banana. This crop occupies about ten million hectares with an annual production of one-hundred million tons. It is part of the basic diet of four-hundred million people and is cultivated in all tropical and subtropical regions constituting the fourth food crop only behind rice, wheat and corn. No fungicide has been found that allows chemical control of the fungus that remains in infected soils for periods exceeding thirty years, so it is urgent to obtain new resistant varieties. This document aims to sensitize society and legislators about the importance of science and technology, with a sustainable global food system approach (availability, policies, economy and culture) to meet the food challenges of the 21st century. ; Peer reviewed

Technical report ; The current challenge of agriculture is to ensure sustainability, being aware that in the next half century we must produce as much as in the previous ten thousand years. At the same time, we should improve crop resilience, in an unquestionable scenario of climate change. The World Food and Agriculture Organization (FAO) urges us to achieve Food Security, which is the situation in which everybody, has physical and economic access to sufficient, safe nutritious food at all times, to satisfy their nutritional needs and preferences, in order to lead an active and healthy life. In recent years we have seen an exponential increase in the knowledge of the molecular basis of genetic traits that are important for food production. Some of these technologies have been developed in Europe, and benefit producers from other parts of the world, from whom our countries then import its products for our consumption. It has been possible to increase the micronutrient content of fruit, delay their ripening or incorporate resistance to viruses, fungi and bacteria. Thus, using tools borrowed from bacterial defence mechanisms (CRISPR-Cas9 and derivatives), it is possible to act in a controlled and timely manner on the desired areas of DNA (Deoxyribonucleic Acid), as could be the case in the fight against TR4 fungus in the banana. This crop occupies about ten million hectares with an annual production of one hundred million tons. It is part of the basic diet of four hundred million people and is cultivated in all tropical and subtropical regions constituting the fourth food crop only behind the rice, wheat and corn. No fungicide has been found that allows chemical control of the fungus that remains in infected soils for periods exceeding thirty years, so it is urgent to obtain new resistant varieties. The document aims to sensitize society and legislators about the importance of science and technology, with a sustainable global food system approach (availability, policies, economy and culture) to meet the food challenges of the 21st century. ; Preprint

Programa Alfa de la Unión Europea para América Latina. Programa Marco Interuniversitario para la política de equidad y cohesión social en la Educación Superior. Red RIAPE 3. 2011. EuropeAid/129877/C/ACT/Multi

l‐galactono‐1,4‐lactone dehydrogenase (GALDH) catalyzes the terminal step of vitamin C biosynthesis in plant mitochondria. Here we investigated the communication between Arabidopsis thaliana GALDH and its natural electron acceptor cytochrome c (Cc). Using laser‐generated radicals we observed the formation and stabilization of the GALDH semiquinone anionic species (GALDHSQ). GALDHSQ oxidation by Cc exhibited a nonlinear dependence on Cc concentration consistent with a kinetic mechanism involving protein–partner association to form a transient bimolecular complex prior to the electron transfer step. Oxidation of GALDHSQ by Cc was significantly impaired at high ionic strength, revealing the existence of attractive charge–charge interactions between the two reactants. Isothermal titration calorimetry showed that GALDH weakly interacts with both oxidized and reduced Cc. Chemical shift perturbations for 1H and 15N nuclei of Cc, arising from the interactions with unlabeled GALDH, were used to map the interacting surface of Cc. For Arabidopsis Cc and yeast Cc, similar residues are involved in the interaction with GALDH. These residues are confined to a single surface surrounding the heme edge. The range of chemical shift perturbations for the physiological Arabidopsis Cc–GALDH complex is larger than that of the non‐physiological yeast Cc–GALDH complex, indicating that the former complex is more specific. In summary, the results point to a relatively low affinity GALDH–Cc interaction, similar for all partner redox states, involving protein–protein dynamic motions. Evidence is also provided that Cc utilizes a conserved surface surrounding the heme edge for the interaction with GALDH and other redox partners. ; Netherlands Organisation for Scientific Research 700.58.441 ; Spanish Ministry of Science and Innovation BIO2010-1493 ; Andalusian Government PAIDI BIO-022 ; the Carbohydrate Research Centre Wageningen CRC-W

Platelets are anuclear cells that are essential for blood clotting. They are produced by large polyploid precursor cells called megakaryocytes. Previous genome-wide association studies in nearly 70,000 individuals indicated that single nucleotide variants (SNVs) in the gene encoding the actin cytoskeletal regulator tropomyosin 4 (TPM4) exert an effect on the count and volume of platelets. Platelet number and volume are independent risk factors for heart attack and stroke. Here, we have identified 2 unrelated families in the BRIDGE Bleeding and Platelet Disorders (BPD) collection who carry a TPM4 variant that causes truncation of the TPM4 protein and segregates with macrothrombocytopenia, a disorder characterized by low platelet count. N-Ethyl-N-nitrosourea-induced (ENU-induced) missense mutations in Tpm4 or targeted inactivation of the Tpm4 locus led to gene dosage-dependent macrothrombocytopenia in mice. All other blood cell counts in Tpm4-deficient mice were normal. Insufficient TPM4 expression in human and mouse megakaryocytes resulted in a defect in the terminal stages of platelet production and had a mild effect on platelet function. Together, our findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder. ; The research participants were enrolled in the Biomedical Research Centres/Units Inherited Diseases Genetic Evaluation (BRIDGE) Bleeding and Platelet Disorders (BPD) study (UK REC10/H0304/66). We are grateful to all the donors who allowed us to use their samples for this study. We thank Sofia Papadia from the NIHR BioResource for organizing the recalls of BRIDGE-BPD participants. The genome sequencing of the BRIDGE-BPD participants was supported by the NIHR BioResource–Rare Diseases (to ET, KD, and WHO). The NIHR BioResource–Rare Diseases is responsible for the delivery of the rare diseases pilot phase of the 100,000 Genomes Project and is funded by the National Institute for Health Research (NIHR; http://www.nihr.ac.uk). Research in the Ouwehand laboratory also receives funding support from the European Commission, NIHR, Wellcome Trust, Medical Research Council (MRC), and British Heart Foundation under numbers RP-PG-0310-1002 and RG/09/12/28096. SKW is supported by an MRC Clinical Training Fellowship (MR/K023489/1). ADM receives support from the Bristol NIHR Biomedical Research Unit for Cardiovascular Disease. This work was supported by a Project Grant (no. 575535), a Program Grant (no. 1016647), a Fellowship (1063008 to BTK and 1058344 to WSA), Project Grants (to PWG and ECH), and an Independent Research Institutes Infrastructure Support Scheme Grant (no. 361646) from the Australian National Health and Medical Research Council; a fellowship from the Sylvia and Charles Viertel Foundation (to BTK); a start-up grant, a fellowship, and a grant from the German Research Foundation (SFB 688, PL707/1-1 and PL707/2-1 to IP); the Kids' Cancer Project (to PWG); a Fellowship from the European Hematology Association (to MRT) and the British Heart Foundation (PG/13/77/30375 to MRT); NHS Blood and Transplant (to WHO and MRT); the Australian Cancer Research Fund; and a Victorian State Government Operational Infrastructure Support Grant.