Suchergebnisse

Foreword -- Introductory considerations -- The earth as a privileged planet -- Mathematical descriptions of population trends -- World population growth: 1900-2010: the un data -- World economic expansion: 1945-1990 -- Energy, population and the environment -- Is the earth overpopulated? -- Abortion and population control -- Government family planning now and in the future -- The rhetoric of population control : does the end justify the means? -- Rate equations approach and the future of world population -- Using a rate equations approach to model world population trends -- Prospects of world population slow down -- Falling birth rates and world population projections : a quantitative discussion (1950-2050) -- Quantitative estimates of the future world population decline -- Malthus's mistake -- Author index

El principal objetivo de este trabajo es proporcionar información a las diferentes instituciones, investigadores y empresas sobre el comportamiento online de los consumidores al adquirir un producto con marca de distribuidor (MDD), basándonos en las relaciones de la MDD con respecto a la cuota MDD online por Comunidades Autónomas en España,. En este estudio se analizaron un total de 17.484 compras online de MDD y 92.094 compras online de marcas de fabricantes. Con estos datos, se han desarrollado modelos de regresión de clases latentes. Los resultados confirman que la relación entre importe de MDD y las variables importe de la compra total, compra de productos sin marca y de marca de fabricante en el canal online varía entre comunidades autónomas, no siguiendo un mismo patrón para los usuarios online, aunque el medio sea el mismo.

Government financial report, concerning the state of the national bank, currency, coining money, debt, the armed forces situated at the border with Brazil, civil war and the provinces. Dated 14 September 1827. Followed by 'Estado general del erario nacional á fin de Julio del año de 1827', signed Santiago Wilde, dated 20 August 1827

El surgimiento de las Fintech provoca un incremento de la competencia para el sector bancario ya que, además de ofrecer servicios más orientados a los clientes y optimizar el uso de las tecnologías, en muchas ocasiones centran su actividad en ofertar en productos que venía ofreciendo la banca tradicional. Por su parte, la banca tradicional encuentra en las apps una herramienta fundamental y una vía para contrarrestar la presión de los nuevos competidores. El presente trabajo se dirige a analizar, a través de un modelo de factor dual los favorecedores e inhibidores de la adopción de las apps de banca móvil. Basado en un trabajo de campo de 240 encuestas, y tras aplicar Modelos de Ecuaciones Estructurales, de acuerdo con los resultados, entre los facilitadores de la adopción de las apps de banca móvil juega un papel fundamental la expectativa de resultado, mientras que la satisfacción y los costes hundidos generan la inercia en el uso de la banca digital

En : Memoria y trabajos : volumen I, año 1955 / del Instituto de Fisiología y Patología Regionales de Tenerife

Published in "Robot 2019: Fourth Iberian Robotics Conference. Advances in Intelligent Systems and Computing, Vol 1093. Silva M., Luís Lima J., Reis L., Sanfeliu A., Tardioli D. (eds)" published by Springer, Cham. Avalaible online at: https://doi.org/10.1007.987-3-030-36150-1_10 ; Natural and human-made disasters require effective victim assistance and last-mile relief supply operations with teams of ground vehicles. In these applications, digital elevation models (DEM) can provide accurate knowledge for safe vehicle motion planning but grid representation results in very large search graphs. Furthermore, travel time, which becomes a crucial cost optimization criterion, may be affected by inclination and other challenging terrain characteristics. In this paper, our goal is to evaluate a search heuristic function based on anisotropic vehicle velocity restrictions for building the cost matrix required for multi-vehicle routing on natural terrain and disaster sites. The heuristic is applied to compute the fastest travel times between every pair of matrix elements by means of a path planning algorithm. The analysis is based on a case study on the ortophotographic-based DEM of natural terrain with different target points, where the ; Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. This work has received funding from the national project RTI2018-093421-B-I00 (Spanish Government), the University of Malaga (Andalucía Tech) and the grant BES-2016-077022 of the European Social Fund.

This work was financially supported by the Ministerio de Economia, Industria y Competitividad (CONSOLIDER CSD2010-00065 and CTQ2017-90852-REDC). R.M.-E. is grateful for the fellowship from the Alfonso Martin Escudero Foundation. ; Chagas disease is a tropical infection caused by the protozoan parasite Trypanosoma cruzi and a global public health concern. It is a paradigmatic example of a chronic disease without an effective treatment. Current treatments targeting T. cruzi are limited to two obsolete nitroheterocyclic drugs, benznidazole and nifurtimox, which lead to serious drawbacks. Hence, new, more effective, safer, and affordable drugs are urgently needed. Selenium and their derivatives have emerged as an interesting strategy for the treatment of different prozotoan diseases, such as African trypanosomiasis, leishmaniasis, and malaria. In the case of Chagas disease, diverse selenium scaffolds have been reported with antichagasic activity in vitro and in vivo. On the basis of these premises, we describe the in vitro and in vivo trypanocidal activity of 41 selenocompounds against the three morphological forms of different T. cruzi strains. For the most active selenocompounds, their effect on the metabolic and mitochondrial levels and superoxide dismutase enzyme inhibition capacity were measured in order to determine the possible mechanism of action. Derivative 26, with a selenocyanate motif, fulfills the most stringent in vitro requirements for potential antichagasic agents and exhibits a better profile than benznidazole in vivo. This finding provides a step forward for the development of a new antichagasic agent. ; Spanish Government CONSOLIDER CSD2010-00065 CTQ2017-90852-REDC ; Alfonso Martin Escudero Foundation

Objective. To establish a multidimensional profile of the health status in a population of southeastern Mexico and analyze the psychometric properties of a translation of the SF-36 survey authorized by the International Quality of Life Assessment Project. Material and methods. The SF-36 was administered to 257 volunteers of a clinic and a control group in a governmental institution. The methodology proposed by the author of the survey to build the health scales was used without modifications. The validity and reliability of the SF-36 adaptation to Mexico was psychometrically analyzed. Results. Eight scales or health concepts related to physical function, physical role, body pain, general health, vitality, social function, emotional role and mental health were constructed. In the health service volunteers, the scale with the lowest mean was general health (63), and that with the highest (89) was physical role. In the control population, the lowest mean was general health (73) and the highest (94.6) was physical function. A comparison of the health scales of both groups showed significant differences in physical function, physical role, body pain, generalhealth and vitality. Conclusions. Based on the psychometric evaluation, the SF-36 shows satisfactory consistency with its supposed validity and reliability, although the translation of certain items will be further analyzed for subsequent modifications. ; Objetivo. Establecer, con la Encuesta SF-36, un perfil multidimensional del estado de salud de una población del sureste de México y analizar las propiedades psicométricas de una traducción de la Encuesta SF-36 autorizada por el Proyecto Internacional de Evaluación de la Calidad de Vida. Material y métodos. La SF-36 se aplicó a 257 participantes voluntarios de una clínica médica y a un grupo control de una institución pública gubernamental. Se utilizó, sin modificar, la metodología de construcción de las escalas de salud propuestas por los autores de la encuesta. Se analizó psicométricamente la validez y la ...

Objetivos. Sistematizar la información publicada sobre la situación y los avances en el logro de los Objetivos de Desarrollo del Milenio relacionados con la salud (ODMS), así como analizar su asociación con algunos factores económicos y los pronósticos de cumplimiento. Métodos. Se realizó una búsqueda de los artículos científicos sobre los Objetivos de Desarrollo del Milenio en general publicados entre el 1 de enero de 2000 y el 31 de agosto de 2006 en las bases bibliográficas electrónicas EBSCO, CSA Illumina, Thomson Gale, SwetsWise y BIREME. Se seleccionaron los artículos originales en inglés o español que evaluaran la situación de los ODMS o sus avances y se refirieran a factores determinantes. Se analizó la distribución de los factores determinantes de la situación de los ODMS o sus avances, los ODMS referidos, el tipo de evaluación, la relación entre los indicadores económicos y la salud, el lugar estudiado, y la situación y los pronósticos del cumplimiento de los ODMS. Se valoró la calidad de los artículos. Resultados. Se identificaron 304 artículos originales, de ellos 114 (37,5%) se ocupaban de uno o varios ODMS. Los objetivos relacionados con la mortalidad infantil y materna fueron los más frecuentemente abordados. De los 39 artículos que evaluaban los ODMS y su relación con los factores económicos, en 13 se consideraban factores económicos relacionados con la equidad, la política o la globalización. Los factores económicos y políticos fueron los más frecuentemente asociados con la situación de los ODMS o sus avances. Conclusiones. Existe una tendencia a utilizar variables económicas vinculadas con las condiciones de la población para analizar la situación de los ODMS y sus avances. Falta información sobre la relación con el gasto gubernamental, el comercio exterior, la ayuda externa y las políticas económicas mundiales. Los pronósticos para lograr los ODMS en los países pobres son desfavorables. ; Objectives. To systematize all the information published on the status of and progress made toward the Health-related Millennium Development Goals (HMDGs), as well as to understand associations with certain economic factors and the potential for success. Methods. A search was conducted for all scientific articles covering the Millennium Development Goals in general, published from 1 January 2000 to 31 August 2006, in the electronic databases of the EBSCO, CSA Illumina, Thomson Gale, SwetsWise, and BIREME. All original articles in English or Spanish that evaluated HMDG status, progress, and determinants were selected. The analysis evaluated the distribution of determinants of HMDG status or progress, the HMDGs referred to, the study type, the relationship between economic indicators and health, the study location, and the status and potential for attaining the HMDGs. The quality of the articles was also rated. Results. Of the 304 original articles found, 114 (37.5%) covered one or more HMDGs. The most frequently addressed goals were those concerning infant and maternal mortality. Of the 39 articles that evaluated HMDGs and their association with economic variables, 13 dealt with economic factors related to equity, policy, or globalization. Economic and policy factors were most frequently associated with HMDG status or progress. Conclusions. There is a definitive trend toward measuring HMDG status and progress according to economic factors that reflect the population's condition. There is an information gap regarding government spending, international commerce, international aid, and global economic policy. The potential for achieving HMDGs in poor countries is low.

<b><i>Introduction:</i></b> Attentional bias (AB) is an implicit selective attention toward processing disorder-significant information while neglecting other environmental cues. Considerable empirical evidence highlights the clinical implication of AB in the onset and maintenance of substance use disorder. An innovative method to explore direct measures of AB relies on the eye-movement activity using technologies like eye-tracking (ET). Despite the growing interest regarding the clinical relevance of AB in the spectrum of alcohol consumption, more research is needed to fully determine the AB patterns and its transfer from experimental to clinical applications. The current study consisted of three consecutive experiments. The first experiment aimed to design an ad-hoc visual attention task (VAT) consisting of alcohol-related and neutral images using a nonclinical sample (<i>n</i> = 15). The objective of the second and third experiments was to analyze whether the effect of type of image (alcohol-related vs. neutral images) on AB toward alcohol content using the VAT developed in the first experiment was different for type of drinker (light vs. heavy drinker in the second experiment [<i>n</i> = 30], and occasional social drinkers versus alcohol use disorder (AUD) patients in the third experiment [<i>n</i> = 48]). <b><i>Methods:</i></b> Areas of interest (AOIs) within each type of image (neutral and alcohol-related) were designed and raw ET-based data were subsequently extracted through specific software analyses. For experiment 1, attention maps were created and processed for each image. For experiments 2 and 3, data on ET variables were gathered and subsequently analyzed through a two-way ANOVA with the aim of examining the effects of the type of image and drinker on eye-movement activity. <b><i>Results:</i></b> There was a statistically significant interaction effect between type of image and type of drinker (light vs. heavy drinker in experiment 2, <i>F</i>(1, 56) = 13.578, <i>p</i> &lt; 0.001, partial η² = 0.195, and occasional social drinker versus AUD patients in the experiment 3, <i>F</i>(1, 92) = 35.806, <i>p</i> &lt; 0.001, partial η² = 0.280) for "first fixation" with large effect sizes, but not for "number of fixations" and "dwell time." The simple main effect of type of image on mean "first fixation" score for AUD patients was not statistically significant. <b><i>Conclusion:</i></b> The data derived from the experiments indicated the importance of AB in sub-clinical populations: heavy drinkers displayed an implicit preference for alcohol-related images compared to light drinkers. Nevertheless, AB fluctuations in patients with AUD compared to the control group were found. AUD patients displayed an early interest in alcohol images, followed by an avoidance attentional processing of alcohol-related images. The results are discussed in light of recent literature in the field.

Rapid cryopreservation of biological specimens is the gold standard for visualizing cellular structures in their true structural context. However, current commercial cryo-fluorescence microscopes are limited to low resolutions. To fill this gap, we have developed cryoSIM, a microscope for 3D super-resolution fluorescence cryo-imaging for correlation with cryo-electron microscopy or cryo-soft X-ray tomography. We provide the full instructions for replicating the instrument mostly from off-the-shelf components and accessible, user-friendly, open-source Python control software. Therefore, cryoSIM democratizes the ability to detect molecules using super-resolution fluorescence imaging of cryopreserved specimens for correlation with their cellular ultrastructure.

Rapid cryopreservation of biological specimens is the gold standard for visualizing cellular structures in their true structural context. However, current commercial cryo-fluorescence microscopes are limited to low resolutions. To fill this gap, we have developed cryoSIM, a microscope for 3D super-resolution fluorescence cryo-imaging for correlation with cryo-electron microscopy or cryo-soft X-ray tomography. We provide the full instructions for replicating the instrument mostly from off-the-shelf components and accessible, user-friendly, open-source Python control software. Therefore, cryoSIM democratizes the ability to detect molecules using super-resolution fluorescence imaging of cryopreserved specimens for correlation with their cellular ultrastructure.