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Étude de la distribution de la densité électronique dans les molécules C2, C3 et C4
In: Bulletin de la Classe des sciences, Band 48, Heft 1, S. 1333-1343
The function δ(M), which measures the effect of the bond formation on the density distribution, has been calculated for C2, C3 and C4. The charge build up is found to have an annular character in the first molecule, whereas in the other two it had its maximum on the internuclear axis. This difference is interpreted on the basis of the number of electrons taking part effectively in the formation of the bonds.
Radiofrequency Neurotomy for Headache Stemming from the Zygapophysial Joints C2/3 and C3/4
In: Central European neurosurgery: Zentralblatt für Neurochirurgie, Band 71, Heft 2, S. 75-79
ISSN: 1868-4912, 1438-9746
ORTA%c3%96%c4%9eRET%c4%b0M%20%c3%96%c4%9eRENC%c4%b0LER%c4%b0N%c4%b0N%20B%c4%b0LG%c4%b0SAYAR%20OYUN%20BA%c4%9eIMLILIKLARININ%20%c4%b0NCELENMES%c4%b0
In: Social sciences studies journal: SSS journal, Band 4, Heft 24, S. 4900-4910
ISSN: 2587-1587
US seeks to dispel 'persistent misconceptions' of AFRICOM . South African DoD plans four C3 projects
In: Jane's defence weekly: JDW, Band 45, Heft 28, S. 17
ISSN: 0265-3818
Entschließung zur Mitteilung der Kommission an den Rat und das Europäische Parlament betreffend die Zuwanderungs- und Asylpolitik (KOM(94)0023-C3-0107/94)
In: Amtsblatt der Europäischen Gemeinschaften. C, Mitteilungen und Bekanntmachungen, Band 38, Heft C 269, S. 156-163
ISSN: 0376-9461
World Affairs Online
Akten des Reichskammergerichts im Hauptstaatsarchiv Stuttgart A–D. Inventar des Bestandes C3. Bearb. von Alexander Brunotte und Raimund J. Weber
In: Zeitschrift der Savigny-Stiftung für Rechtsgeschichte. Germanistische Abteilung, Band 113, Heft 1, S. 543-544
ISSN: 2304-4861
Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications
41 p.-11 fig. ; C3 is the central component of the complement system. Upon activation, C3 sequentially generates various proteolytic fragments, C3a, C3b, iC3b, C3dg, each of them exposing novel surfaces, which are sites of interaction with other proteins. C3 and its fragments are therapeutic targets and markers of complement activation. We report the structural and functional characterization of four monoclonal antibodies (mAbs) generated by immunizing C3-deficient mice with a mixture of human C3b, iC3b and C3dg fragments, and discuss their potential applications. This collection includes three mAbs interacting with native C3 and inhibiting AP complement activation; two of them by blocking the cleavage of C3 by the AP C3-converase and one by impeding formation of the AP C3-convertase. The interaction sites of these mAbs in the target molecules were determined by resolving the structures of Fab fragments bound to C3b and/or iC3b using electron microscopy. A fourth mAb specifically recognizes the iC3b, C3dg, and C3d fragments. It binds to an evolutionary-conserved neoepitope generated after C3b cleavage by FI, detecting iC3b/C3dg deposition over opsonized surfaces by flow cytometry and immunohistochemistry in human and other species. Because well-characterized anti-complement mAbs are uncommon, the mAbs reported here may offer interesting therapeutic and diagnostic opportunities. ; Work in this report has been funded by the Spanish "Ministerio de Economía y Competitividad" (SAF2011-26583 and SAF2015-66287-R to SRdC and SAF2014- 52301-R to OL) and the Seventh Framework Programme European Union Project EURenOmics (305608) to SRdC. In addition, this work has been supported by a grant from the Autonomous Region of Madrid (S2010/BMD-2316) to SRdeC and OL. ; Peer reviewed
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Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications
C3 is the central component of the complement system. Upon activation, C3 sequentially generates various proteolytic fragments, C3a, C3b, iC3b, C3dg, each of them exposing novel surfaces, which are sites of interaction with other proteins. C3 and its fragments are therapeutic targets and markers of complement activation. We report the structural and functional characterization of four monoclonal antibodies (mAbs) generated by immunizing C3-deficient mice with a mixture of human C3b, iC3b and C3dg fragments, and discuss their potential applications. This collection includes three mAbs interacting with native C3 and inhibiting AP complement activation; two of them by blocking the cleavage of C3 by the AP C3-converase and one by impeding formation of the AP C3-convertase. The interaction sites of these mAbs in the target molecules were determined by resolving the structures of Fab fragments bound to C3b and/or iC3b using electron microscopy. A fourth mAb specifically recognizes the iC3b, C3dg, and C3d fragments. It binds to an evolutionary-conserved neoepitope generated after C3b cleavage by FI, detecting iC3b/C3dg deposition over opsonized surfaces by flow cytometry and immunohistochemistry in human and other species. Because well-characterized anti-complement mAbs are uncommon, the mAbs reported here may offer interesting therapeutic and diagnostic opportunities. ; Work in this report has been funded by the Spanish "Ministerio de Economía y Competitividad" (SAF2011‐26583 and SAF2015‐66287‐R to SRdC and SAF2014‐52301‐R to OL) and the Seventh Framework Programme European Union Project EURenOmics (305608) to SRdC. In addition, this work has been supported by a grant from the Autonomous Region of Madrid (S2010/BMD‐2316) to SRdeC and OL. ; Sí
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Intraspecific variability of Sedobassia sedoides plants with intermediate C3-C4 type of photosynthesis under osmotic stress conditions
In: Сибирский экологический журнал, Band 29, Heft 1, S. 76-86
C3. Breaking The Silence, "Children And Youth: Soldiers' Testimonies 2005-2011," West Jerusalem, October 2012 (Excerpts)
In: Journal of Palestine studies: a quarterly on Palestinian affairs and the Arab-Israeli conflict, Band 42, Heft 2, S. 180
ISSN: 0377-919X, 0047-2654
C3. Acting Prime Minister Ehud Olmert, Statement on the Hamas Legislative Victory, Jerusalem, 29 January 2006
In: Journal of Palestine studies, Band 35, Heft 3, S. 211-212
ISSN: 1533-8614
C3. Acting Prime Minister Ehud Olmert, Statement on the Hamas Legislative Victory, Jerusalem, 29 January 2006
In: Journal of Palestine studies: a quarterly on Palestinian affairs and the Arab-Israeli conflict, Band 35, Heft 3, S. 211
ISSN: 0377-919X, 0047-2654