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I wish to thank John Cochran, Lawrence White, Ivo Sarjanovic, Lane Boyte,Thomas McQuade, Sven Thommesen, and two anonymous referees for their helpful comments.

I thank William Coleman, Tony Endres, Keith Forster, Peter Groenewegen,Jeff Lipkes, David Reisman, John Whitaker, Mike White, and two anonymous referees for extremely useful comments and suggestions on earlier versions of this article. I retain full responsibility for any remaining shortcomings. I am also grateful to the librarians and archivists at Hatfield House, the National Library of Scotland, and the Central Liverpool Library for granting me permission to reproduce extracts from, respectively, the Marquis of Salisbury papers, the Sir Robert Liston papers, and the Thornton letters preserved in the Derby Collection. Finally, I record my gratitude to the staff of the Oriental and India Office Collections for their friendly and unfaltering assistance during the course of many years of research there.