The stalemate between domestic political forces continues to impede reforms while the ongoing Syrian conflict is imposing a security, political, and economic toll on Lebanon. The stalemate in the executive and legislative branches of government remains an impediment to reforms. Important bills, regulations and appointments are still pending in cabinet and Parliament. This deadlock could well last until the June 2013 Parliamentary elections. The Syrian crisis is fueling political divide among sectarian lines in Lebanon, leading to sporadic violence incidents across the country. These incidents have materially impacted the economy, with sectors such as tourism strongly affected. Politically, the turmoil has sparked social unrest and overshadowed the reform drive. To tackle the situation, the government devised a minimum political understanding to restore order in the country. Political backing for a large security operation has also been given; results have yet to fully materialize. The fiscal deficit and public debt positions remain major challenges for the Lebanese economy. The fiscal deficit deteriorated somewhat during the first half of the year. Notwithstanding this slight widening of the fiscal balance, public debt continues its recent downward trend. Rising international commodity prices and the Syrian crisis are adding further pressure on both trade and current account deficits.
Doing business sheds light on how easy or difficult it is for a local entrepreneur to open and run a small to medium-size business when complying with relevant regulations. It measures and tracks changes in regulations affecting 10 areas in the life cycle of a business: starting a business, dealing with construction permits, getting electricity, registering property, getting credit, protecting investors, paying taxes, trading across borders, enforcing contracts and resolving insolvency. In a series of annual reports doing business presents quantitative indicators on business regulations and the protection of property rights that can be compared across 183 economies, from Afghanistan to Zimbabwe, over time. This economy profile presents the doing business indicators for Sweden. To allow useful comparison, it also provides data for other selected economies (comparator economies) for each indicator. The data in this report are current as of June 1, 2011 (except for the paying taxes indicators, which cover the period January-December 2010).
This tenth edition of Doing Business sheds light on how easy or difficult it is for a local entrepreneur to open and run a small to medium-size business when complying with relevant regulations. It measures and tracks changes in regulations affecting eleven areas in the life cycle of a business: starting a business, dealing with construction permits, getting electricity, registering property, getting credit, protecting investors, paying taxes, trading across borders, enforcing contracts, resolving insolvency and employing workers. Doing Business presents quantitative indicators on business regulations and the protection of property rights that can be compared across 185 economies, from Afghanistan to Zimbabwe, over time. The indicators are used to analyze economic outcomes and identify what reforms have worked, where and why. This economy profile presents the Doing Business indicators for Pakistan. To allow useful comparison, it also provides data for other selected economies (comparator economies) for each indicator. The data in this report are current as of June 1, 2012 (except for the paying taxes indicators, which cover the period January - December 2011).
This report begins by documenting the Palestinian Authority's (PA's) ongoing fiscal crisis that threatens its ability to provide basic services to the population. In 2011, the PA required about US$1.5 billion dollars in budget support, of which US$200 million to cover development expenses not funded directly by donors. However, it only received about US$814 million in budget support and US$169 million in development financing, for a total of US$983 million. Ultimately, the PA can only hope to achieve fiscal sustainability through a combination of sustained private sector growth and continued internal reforms. Robust private sector growth is necessary for the PA to generate the revenues needed to sustain service delivery. Yet the private sector remains stifled as a result of Israeli restrictions on access to natural resources and markets. The West Bank has experienced a slowdown in economic growth in 2011, combined with double-digit growth in Gaza. The recovery in Gaza can be attributed to a combination of aid inflows and easing of restrictions on entry of goods from Israel-though it is important to keep in mind that the average Gaza today is worse off than s/he was back in the late nineties. The recent growth in Gaza is also driven largely by a boom in the construction sector, and Gaza infrastructure exhibits such gaps and disrepair that major investments are necessary and would generate important employment as well as future growth. The slowdown in growth in the West Bank, on the other hand, is the result of falling donor support, uncertainty caused by the PA's fiscal crisis, and lack of significant new easing of restrictions by the Government of Israel (GoI).
The objective of this policy note is to identify likely factors driving rice prices and suggest options to manage rice price volatility in the future. It also provides a snapshot of recent developments in the rice sector, and describes rice and food price trends and their implications. Based on these findings, the note discusses policy options. The policy brief has six chapters, including this introduction. Chapter two provides a brief outline of the rice sector. Chapter three describes recent trends in world and Lao food prices. It also provides insights into likely macroeconomic and household welfare impacts of rice price inflation. Chapter four discusses the potential causes of rice price inflation, as suggested by other reports and people interviewed. Chapter five analyzes the role of the regional rice market in determining prices, which this policy brief identifies as the primary cause of the glutinous rice price hike. Chapter six concludes by presenting recommendations.
Developing a diagnostic and action framework for donor-assisted governance reform in conflict-affected countries and fragile states was the objective of a program implemented by the World Bank's Social Development Department (SDV) and funded by the French Ministry of Foreign Affairs. The first phase of the program developed lessons and outcomes based upon a review of international experience of governance reform in fragile and conflict-affected states. A major objective was to identify specific approaches and activities that will be most effective in strengthening institutions, promoting transparency and accountability, and enhancing capacity at local and national levels. This phase also derived lessons on the utility and shortcomings of governance-related diagnostic tools in designing and evaluating country strategies and programs in fragile states. A key issue concerns methodology. What type of analytical method provides a more useful assessment: country-specific analyses of the political economy, indicators designed for purposes of cross-country comparison, indices that rank state fragility, or some combination of diagnostic tools? The second phase of the program also was in two parts. Cote d'Ivoire's poverty reduction strategy process was used as an entry point for an initiative that facilitated process and method-oriented exercises for local stakeholders on the how rather than the what of policy development in an effort to build governance capacity. One result is a model that may serve for future engagement in other fragile and conflict-affected countries. The second part of this phase is an ongoing effort to work with local partners in the Central African Republic and Chad to identify strategies that could strengthen access to justice at the local level. Activities include assessing the strengths and weaknesses of formal and informal justice systems and mapping community-based practices and informal justice systems, including some under the aegis of NGOs, as well as identifying possible linkages to state justice systems. The paper will first examine the concepts of state fragility and governance in terms of donor engagement. Part two will discuss the lessons (opportunities and constraints), diagnostic tools and entry points for governance reform. Part three will offer conclusions.
Norms in development are typically established at the global level to solve complex development challenges on the ground. These norms are standards of expected behavior about how things ought to be conducted and are deemed crucial for societies to flourish. Global norms, however, often fail to successfully diffuse to local contexts. The author intend to argue in this report that many initiatives are effective in putting norms on the global agenda, but few of these norms lead to transformational change on the ground because of cultural and political economy challenges that were not considered in the norm formation or in the advocacy campaign process. Nonetheless, there are lessons to consider that could lead to more successful outcomes. This report explores the journey of norms in development, from emergence to implementation. Specifically, it seeks to identify effective strategies for norms to take root and make part of the global and domestic agendas and limits. It also identifies challenges to the implementation of norms and some possible strategies and tools to overcome these challenges. The report draws from various global policy advocacy campaigns with a particular focus on governance; it also includes notable historic campaigns, such as Britain's antislavery campaign.
Mongolia has very significant natural resources and a large part of the population is dependent on them for their daily living. The impact of the state of the environment on the living standards of herders is obvious, but also Mongolians living in the capital Ulaanbaatar have learned that air pollution, especially in winter, and other environmental problems have a deep impact on their living standards. The Government of the Netherlands has established a Trust Fund at the World Bank to support environmental activities in Mongolia. Under this framework, the World Bank contracted the first Environment and Natural Resource Management Socio-economic Survey for Mongolia (ENRMSS) to the National Statistical Office and an international consultant, the aim of this survey is to investigate public views on environmental issues and to measure the impact of environmental problems on human welfare, measured in economic terms. The first part of section five is devoted to wildlife hunting, fishing and wild nuts and fruits gathering, while the second part of this section focuses on energy consumption. Both complete and complement the information on consumption estimated in the Socioeconomic Survey (SES). Section six presents perception and opinions of herders on issues such as the number of animals in Mongolia or the best way to manage animal movements. Finally, section seven shows results on perceptions and opinions of Mongolians regarding nature and the environment.
The World Bank is making strides in mainstreaming gender-sensitive approaches to climate action on the ground. Ensuring that men and women have equal access to education, economic opportunities, productive inputs and equal chances to become socially and politically active can generate broad productivity gains, and lead to more inclusive and greener development path for all. For the World Bank, gender analysis is an integral aspect of the upstream social analysis that is required to inform both development policy lending (DPL) and investment lending (IL). It helps identify and suggest ways to mitigate possible risks in terms of exacerbating gender inequality, and highlight opportunities to enhance positive outcomes for gender equality. The entry points for such upstream gender analysis include Poverty and Social Impact Analysis (PSIA) in the case of DPL, climate financing mechanisms are beginning to adopt gender-sensitive approaches in program design and results frameworks, but more needs to be done. Much can be done to improve the effectiveness of climate finance and actions on the ground by ensuring that gender relations are taken into account in design, implementation, and measurement of results. But this can only be achieved through a concerted effort to apply a gender lens in climate finance mechanisms. It matters for development, and it matters for effective action on climate change.
The point of this paper is to emphasize the importance and role of leadership for African growth, development, and poverty reduction. It is also an attempt to project a more objective assessment of leadership issues during the first three to four decades of African independence. Agreeing on shared responsibilities for Africa's failures in its early years will enable all who want to take part in the continent's renewal to focus on the partnership that is now needed to close a sad chapter in Africa's history, and open a new one. The core elements of such a partnership have evolved in the last decade, and this paper argues passionately for the political will, in Africa and outside, for their realization.
Pharmaceuticals are essential to achieve health outcomes, but are at the same time a major cost factor in every health system. From a patient perspective, access to pharmaceuticals is a proxy for the functioning of the health system. With increasing economic strength, patients become more demanding with regard to access to modern, sophisticated drugs and providers become more aggressive in marketing those drugs. This paper reflects the situation in the pharmaceutical sector in Turkey, identifies critical issues, and discusses policy options based on current trends and the overall policy objectives of the Turkish government. This paper is structured as follows: chapter one gives introduction; chapter two gives overall policy objectives in the pharmaceutical sector in Turkey; chapter three presents institutional and regulatory framework; chapter four presents reimbursement rules; chapter five focuses on governance issues in the pharmaceutical sector; chapter six gives market overview; chapter seven gives payment for pharmaceuticals in Turkey; chapter eight presents prescribing practices - rational use of medicines; and chapter nine gives conclusions and way forward.
This article questions current empirical practice in the study of growth. It argues that much of the modern empirical growth literature is based on assumptions about regressors, residuals, and parameters that are implausible from the perspective of both economic theory and the historical experiences of the countries under study. Many of these problems, it argues, are forms of violations of an exchangeability assumption that implicitly underlies standard growth exercises. The article shows that these implausible assumptions can be relaxed by allowing for uncertainty in model specification. Model uncertainty consists of two types: theory uncertainty, which relates to which growth determinants should be included in a model; and heterogeneity uncertainty, which relates to which observations in a data set constitute draw from the same statistical model. The article proposes ways to account for both theory and heterogeneity uncertainty. Finally, using an explicit decision-theoretic framework, the authors describe how one can engage in policy-relevant empirical analysis.
Not Available ; Quality Protein Maize (QPM): Importance and production requirements Ramesh Kumar, DP Chaudhary, AK Das and Sujay Rakshit ICAR - Indian Institute of Maize Research, Ludhiana Introduction The present scenario of increasing population puts pressure on agriculture not only to increase production and productivity but also the grain quality. It is imperative that increasing production of food crops to ensure food and nutritional security of the nation has become a necessity rather a matter of choice. However, the challenge to meet the growing demand for food seems to be a daunting task due to rapid reduction in agricultural land, reduced availability of water resources and climate change. Moreover, ensuring the nutritional security or improving the nutritional status of the poorer section on sustainable manner is an added challenge. The present food production scenario indicates that much of the future food production is expected to come from coarse cereals, particularly maize because of its highest yield potential as compared to any other food crop. Maize has already credited as queen of cereal and further due to its high content of carbohydrates, fats, proteins and some of the important vitamins and minerals, it has also acquired a well - deserved reputation as 'poor man's nutri - cereal'(Kumar et al .,2012). Maize contributes 15% of the world's protein and 19% of the calories derived from food crops (Vasal SK, 2002). Millions of people in the world, and particularly in developing countries, derive a part of their protein and daily calorie requirements from maize (Mbuya et al.,2011). In recent years the diversified uses of maize as food, feed and as an industrial raw material is also increasing. In addition to this maize is part of the livestock - to - meat cycle across the world (Tanumihardjo et al., 2019). The food processing industries are coming up with new value - added products of corn like flakes, chips, biscuits, sooji etc. Increased demand from consumers has led to higher per capita consumption and demand for maize. Improved growth in Indian economy has increased per capita income thereby improving the purchasing power of its people. The consequence of all these events has led to change in the food habits with an increased non - vegetarian population of the country. The increased non - vegetarian populations had its own cascaded of events on food/feed and meat industries. The increased demand of meat has increased the demand of maize from poultry and piggery feed industries. In this particular context, quality protein maize (QPM) can play a crucial and very important special role in ensuring the food and nutritional security of the country. Nutritive Value of Quality Protein Maize The maize grain on an average contains around 15 % moisture, 8 - 12 % protein, 2 - 4 % fat, 3 % fibre, 67 - 72 % starch and around 1.5% minerals. Hence it is a good source of carbohydrates, fats, proteins and some of the important vitamins and minerals and, therefore, termed as nutri - cereal. Majority of the population depend on cereals for their livelihood and maize is the staple cereal food for several million people, especially in the developing countries across Sub - saharan Africa who derive their >30% of the total dietary protein and >20% of the daily calories requirements from maize as it supplies many macro and micronutrients necessary for human metabolic needs. The kernel protein is made up of five different fractions, viz., albumin 7 %, globulin 5 %, non - protein nitrogen 6 %, prolamine 52 % and glutelin 25% and the left - over 5 % is residual nitrogen. The quality of maize protein is poor due to the presence of large concentration of an alcohol soluble protein fraction, prolamine also known as zein in the endosperm. Zein is very low in lysine and tryptophan content and since this fraction contributes more than 50 percent of the total protein, the maize protein is, therefore, deficient in lysine and tryptophan content. On the other hand, zein fraction contains very high amount of leucine and imbalanced proportion of isoleucine. The ill - proportion of four essential amino acids in normal maize kernels results in poor protein quality of traditional maize kernels affecting its biological value i.e. the availability of protein to the body. Thus, the composition of maize protein has an in - built drawback of being deficient in two essential amino acids, viz., lysine and tryptophan. However, high - quality protein sources, such as eggs, meat, dairy products and legumes provide total or complementary sources of these amino acids, but many rural poor have limited access to these foods. Therefore, populations depending on maize as their staple food generally show the protein deficiency disorders like Marasmus and Kwashiorkar. In addition, maize lacks vitamin B and also due to high concentrations of phytate some minerals in the maize grain have low bioavailability. Therefore, a need was felt to improve the biological value of protein in maize varieties. In early 1960s the breeders at Purdue University obtained the natural mutants of maize which have soft and opaque grains. The biochemical and genetic analysis of mutant kernels revealed that they contain higher concentration of lysine and this nutritionally superior maize was named opaque - 2 maize, after discovering that "opaque - 2" single gene mutation is responsible for the improved protein quality (Mertz et al., 1964). It was mentioned that the original mutants obtained were soft and opaque, but they have some draw - backs like higher susceptibility to storage and ear rot. Therefore, to overcome this problem International Center for Maize and Wheat Improvement (CIMMYT) introduced endosperm modifier genes through continued recurrent selection breeding programme led by Dr. S. K. Vasal and team. As a result, hard endosperm o2 stocks were developed and were designated as quality protein maize (QPM) to distinguish it from soft o2 strains. Quality protein maize (QPM) was created by selecting genetic modifiers that convert the starchy endosperm of an opaque2 (o2) mutant to a hard, vitreous phenotype. However, not all of the hard endosperm o2 lines retained high levels of the critical amino acids. Later the genetic studies on QPM have shown that there are multiple, unlinked o2 modifiers (OPM), but their identity and mode of action are unknown. In QPM the concentration of zein is lowered by 30 percent, as a result the lysine and tryptophan content increases in comparison to maize. The lower contents of leucine in QPM further balance the ratios of leucine to isoleucine (Table1). The balanced proportion of all these essential amino acid in QPM enhances the biological value of protein (Table - 2). The true protein digestibility of maize vis - à - vis QPM is almost same, but the biological value of QPM is just double as compared to maize varieties (Fig1), rather it is highest among all cereals and pulses (Fig1). The reason behind it is that all cereals except QPM are deficient in lysine, an essential amino acid and all pulses are deficient in another essential amino acid methionine. Maize breeders have developed several QPM hybrids by incorporating opaque - 2 mutant gene modifiers in different parental lines. QPM looks and taste like normal maize, but it contains nearly twice the quality of lysine and tryptophan along with balanced amino acid profile. QPM as Food and Nutritional Security In India, tribal population constitutes approximately 10% of the total population and is found in most parts of the country especially in the states of Madhya Pradesh, Assam, Nagaland, Gujarat, Chhattisgarh, Jharkhand, etc. Thus, a sizable tribal population exist which is economically deprived. Further, most of tribal population depends on maize as their basic diet. In these areas the scope for QPM to ensuring food and nutritional security is paramount. Substituting maize with QPM is a viable option for ensuring their nutritional requirements. Tribal peoples are acknowledged to have very close association with ecosystem and environment because of their dependence on nature directly for daily requirements. However, the problem of malnutrition arises due to inadequate intake of nutrients in the diet. The situations are almost same in some African countries. Several studies are conducted on human beings and animal and are continue to be conducted on positive health benefits of QPM consumption in their daily diet. Gunaratna et al., 2010 reported that consumption of QPM instead of maize leads to an increase in growth rate of height and weight by 12 and 9%, respectively in infants and young children coming from population with mild to moderate under nutrition where maize is the significant component of the diet. This happened due to the higher biological value of QPM as compared to the maize (Table 2). The results are encouraging and based on these results the Indian policy makers can think of providing QPM in the tribal belt or in the areas where there is a problem of malnutrition. Government of India can also think of introducing QPM in public distribution system and QPM based food in mid - day meal in schools and Aanganwadis. Government of India has already started Tribal - Sub Plan (TSP) and under this programme the Directorate of Maize Research has provided QPM hybrid seeds for cultivation in the areas where tribal population is more. Some on - farm trainings have also being organized in these areas for creating awareness to use QPM as staple food. QPM and Animal feed Maize is an integral part of the animal feed used in India and outside. There are several studies where maize has been replaced by QPM as an ingredient of animal feed and encouraging results have been observed in case of broilers, chickens and pigs. Feed trials have repeatedly shown that pigs fed with QPM grow twice as fast as those fed with commercial maize (Krivanek et al., 2007). Some nutritional studies with pigs and chicken diets have shown that performance is improved when QPM is substituted for maize without any additional protein supplement. In broiler diet, the substitution of QPM for maize at a rate of 60% substantially reduces the need for soybean meal and therefore the cost (Subsuban et al., 1990). Similarly, in an experiment with finisher pigs, less soybean meal was needed to maximize performance in diets based on QPM compared with diets having maize. Beef steers fed on high–lysine maize gained faster weight compared to those fed on normal maize. Thus, QPM can reduce the cost of animal feed by decreasing the expenditure incurred on more expensive high protein sources. Linear programming models allow feed companies to identify the cheapest way of providing the minimum dietary requirements for farm stock. Calculations for pig and poultry ration containing maize, QPM, sorghum, soybeans meal and synthetic lysine and tryptophan showed that the usage of QPM instead of maize resulted in saving of 2.8% on chickens feed and 3.4 % on pig feed (Lopez - Pereira, 1992). It is also evident that if QPM was to replace maize in broiler feed in Kenya, the 5% cost reduction would translate into a gain of US dollars 300,000 either as reduced costs for farmers or profit for feed manufactures. In India also it can happen if we use QPM as an ingredient in animal feed. It will help in reducing the cost of feed as well as in increase the growth of the animal either it is broiler, chicken, pig or cattle. The broilers and chickens fed with QPM matured in less time as compared to non QPM fed ones and the farmer benefitted by selling more number of animals in a short span of time. Additionally, QPM fed pigs experience rapid weight gain and are ready for market sooner or can provide an additional quality protein source for small farm families. Impact of QPM Babies and adults consuming QPM are healthier and at lower risk for malnutrition disorders such as marasmus and kwashiorkor. Data from Latin America and Africa showed the role of QPM in reversing the effects of malnutrition in those who are already affected. QPM offers 90% the nutritional value of skim milk, the standard for adequate nutrition value. At a time when UNICEF reports that 1,000,000 infants and small children are starving each month, the inclusion of QPM in daily rations improves health and saves lives. Additionally, QPM fed pigs experience rapid weight gain and are ready for market sooner or can provide an additional quality protein source for small farm families. The commercial success of QPM can be achieved as several QPM hybrids have been developed and tested across varying climatic and growing conditions. At present QPM varieties are grown on roughly 9 million acres (36,000 km²) worldwide. Meanwhile, QPM research and development have spread from Mexico to Latin America, Africa, Europe, and Asia. In Guizhou, the poorest province in China, where QPM hybrid yields are 10% higher than those of other hybrids, and the crop has enabled new pig production enterprises, bringing increased food security and disposable income. In total, the QPM germplasm is being grown worldwide and it is contributing over $1 billion annually to the economies of developing countries. Production requirements Isolation distance The foremost requirement for QPM cultivation is isolation distance of minimum 400 meters. There should not be any other maize crop (non - QPM) in surrounding of 400 meters. The opaque - 2 gene is expressed when it present in homozygous conditions, if any other maize crop is there in surrounding area and pollen of other maize will fall on QPM silk and it will create heterozygous conditions resulting opaque 2 gene will not express that is why it is strongly recommended that we will have to grow QPM crop in isolation or we can grow this in a specified area where only QPM is grown. Soil and climate QPM can be grown successfully in a wide range of soil from loamy sand to clay. But it performs well in high organic matter content soil with high water holding capacity and neutral in pH. Soil should have high drainage capacity as maize is more susceptible to water logging condition. QPM can be successfully grown in varied climatic conditions though out the country in an altitude from mean sea level to 3000 m height. Selection of cultivar A no. of QPM hybrids have been released in India for cultivation namely, HQPM1, HQPM 4, HQPM 5, HQPM 7, Shaktiman 1, Shaktiman 2, Shaktiman 3, Shaktiman 4, Shaktiman 5, Pusa HM 8, Pusa HM 9, Vivek QPM 9 and Pusa Vivek QPM 9 improved. The farmers can select anyone among these hybrids in consultation with local maize breeder/agriculture expert. Sowing time QPM can be grown in all the seasons viz. kharif, rabi and spring. Seed rate Seed rate varied according to seed size, season, sowing method. But on an average 20 kg/ha is optimum for higher yield. Seed treatment To protect the seed from seed and soil borne diseases and pest seed should be treated before sowing with fungicide Bavistin + Captan in 1:1 ratio @ 2 g/kg seed. Method of sowing Line sowing in furrows at 60 - 70 x 20 - 25 cm (row x plant) spacing to obtain the optimum plant population of 70000 to 80000 per ha with sowing depth of 4 - 5 cm is the best method. Nutrient management The requirement of nutrient and fertilizers are as follows: Nutrient Dose Form Requirement (Kg/ha) N 150 - 180 Urea 3255 - 3906 P2O5 70 - 80 SSP 438 - 500 K2O 70 - 80 MOP 116 - 133 Besides that ZnSO4 @ 25 kg/ha and FYM @ 10 t/ha is required for high productivity of QPM. FYM should be applied at 10 - 15 days before sowing. The whole amount of SSP, MOP, ZnSO4 and 10% of urea should apply as basal in furrows. The remaining urea should be applied in three split applications. 20% urea at 4 leaf stage, 40% at 8 leaf stage and remaining 30% at flowering stage. Fertilizers should be applied from both sides of rows. Three days before application of fertilizers light hoeing is needed for optimum use of nutrients by crops. Water management If irrigation facility is available then irrigation should be done in furrows up to 2/3rd height of the ridge at knee high stage, flowering and grain filling stage. Weed management Weed is a serious problem of maize in Tirap district of Arunachal Pradesh which may causes yield loss up to 35%. Therefore, timely weed management is essential for good yield. Pre - emergence herbicide atrazine @ 1.0 - 1.5 kg a.i./ha in 600 litre water is very effective for control of weed. Tembotrione @ 262 ml in 375 litre water is recommended for post - emergence application and it should be applied when the crop is 25 - 30 days old. Earthing up Earthing up is a very essential operation in QPM cultivation. Earthing up should be done when the crop is 35 - 40 days old. Insect Pest Management: Maize stem borer (Chilo partellus) The pest lays eggs on the lower surface of central whorl leaf and the larvae enter the plant from the central whorl and eventually results in dead heat formation Foliar application of Chlorantraniliprole 18.5 SC @ 0.3 ml / litre water in 200 litre water per ha is quite effective The spray should be done at the appearance of symptoms on 2 - 3 weeks old crop. It can also be controlled by release of 8 trico cards (Trichogramma chilonis) per ha at 10 & 17days after germination. Pink stem borer (Sesamia inferens) This insect is more serious in peninsular India during rabi season. Foliar application of Chlorantraniliprole 18.5 SC @ 0.3 ml / litre water in 200 litre water per ha is quite effective. The spray should be done at the appearance of symptoms on 2 - 3 weeks old crop. Shoot fly (Atherigona spp.) It is more serious during spring season in northern India. It lays eggs on emerging seedlings and maggets cuts the growing point resulting in dead heart formation. Seed treatment gaucho 600FS @ 6.0 ml/ kg seed is most effective. Fall Armyworm (Spodoptera frugiperda) It is new exotic pest in maize ecosystem. It feeds heavily on central whorl leaves and it is more serious on crop up to six weeks old. It lays eggs in clusters on upper and lower surface of the leaves. Young larvae cause papery windows on leaves while grown larvae feeds by making bigger irregular wholes, cut the leaf margins and may damage the central whorl leaves also. The infected plants are filled with its excreta. The seed treatment with Cyantraniliprole 19.8% + Thiamethoxam 19.8% FS @ 6 ml/kg of seed offers protection for 15 - 20 days of crop growth against Fall Armyworm is quite effective up to 3 leaves/ 20 days old crop. Release of egg parasitoids viz., Telenomus remus (4000/ ac) or Trichogramma pretiosum @ 50,000/acre at 7 and 14 days following first spray using neem formulation with the trap catch of one moth/day observed continuously. Note: Parasitoid release may be alternated with neem spray at weekly intervals, but not to be applied simultaneously. For management of early instar larvae with a damage level of 5 - 10%, whorl application of Bacillus thuringiensis v. kurstaki formulations 2% (400g/acre) applied @ 2g/l or Metarhizium anisopliae or Beauveria bassiana (1kg/acre) applied @ 5 g/liter is recommended. If infestation is more than 10%, spray with anyone of the recommended insecticides with label claim, viz., Chlorantraniliprole 18.5 SC (80 ml/acre) applied @ 0.4 ml/l or Thiamethoxam 12.6 % + Lambda cyhalothrin 9.5% ZC (50ml/acre) applied @ 0.25 ml/l or Spinetoram 11.7 % SC (100ml/acre) applied @ 0.5 ml/l is recommended. DISEASE MANAGEMENT Turcicum leaf blight: Spray Zineb/Meneb @ 2.5 - 4.0 g/l water 2 - 4 times at 8 - 10 days intervals as a control measure. Maydis leaf blight: It can be controlled by 2 - 4 times spraying of Dithane Z - 75 or Zineb @ 2.4 - 4.0 g/l water at 8 - 10 days intervals after first appearance of the symptoms of disease. Banded leaf and sheath blight: Seed treatment of peat - based formulation (Pseudomonas fluorescence) @ 16 g/kg of seed or soil application @ 7 g/l water as soil drenching or foliar spray of Sheethmar (Validamycin) @ 2.7 ml/l water is effective against this disease. Bird management In some places mature cobs are damaged by birds. In such situations matured cob can be protected from bird damage by tying cobs with leaf of the same plant. Harvesting Harvesting should be done at optimum moisture content (20%) in grain to avoid postharvest loses due to store grain pest and diseases. Harvesting immediately after shower should be avoided. The harvested cobs should be sun dried before shelling and should be shelled at 13 - 14% grain moisture. During storage the moisture content of grain should be 8 - 10 %. Table 1. Essential amino acid content of maize Amino acid Normal (mg per g N) QPM (mg per g N) Lysine Isoleucine Leucine Sulphur amino acid Aromatic amino acid Threonine Tryptophan Valine 177 206 827 188 505 213 35 292 256 193 507 188 502 199 78 298 Table 2. Protein quality of maize Quality measures Normal QPM True protein digestibility Biological value (%) Amount needed for equilibrium 8040 - 47547 92 80 230 References Gunarathna NS, De Groote H, Nestel P, Pixley KV and McCabe GP. (2010). A meta - Analysis of community level studies on quality protein maize. Food Policy. 35: 202 - 210. Krivanek AF, De Groote H, Guraratna NS, Diallo AO and Friesen D. (2007). Breeding and Disseminating quality protein maize (QPM) for Africa. African J. Biotech. 6 (4):312 - 324. Kumar RS, Kumar B, Kaul J, Chikkappa GK, Jat SL, Parihar CM and Kumar A. (2012). Maize research in India - historical prospective and future challenges. Maize Journal. 1(1):1 - 6. Lopez - Pereira MA.(1992). The economics of quality protein maize as an animal feed: Case Studies of Brazil and EI Salvador, CIMMYT, Mexico, DF. Mertz ET. (1970). Nutritive value of corn and its products. In: Inglett GE, editor. Corn: culture, Processing, products. Westport, Conn.: Avi Publishing. p 350–9. Subsuban CP, Olanday PO, Cambel IH. (1990). Advantages of quality protein maize (QPM) In broiler ration. Research and Development Journal (Philippines). 1(1): 5 - 17. Vasal, S.K. (2002). Quality protein maize development: An exciting experience. In Integrated Approaches to Higher Maize Productivity in the New Millennium, Proceedings of the Seventh Eastern and Southern Africa Regional Maize Conference, Nairobi, Kenya,5–11February2002;Friesen,D.,Palmer,A.F.E.,Eds.;CIMMYT(InternationalMaize and Wheat Improvement Center) and KARI (Kenya Agricultural Research Institute): Nairobi, Kenya, pp. 2–9. 3. Mbuya, K.; Nkongolo, K.K.; Kalonji - Mbuyi, A. (2011). Nutritional analysis of quality protein maize varieties selected for agronomic characteristics in a breeding program. Int. J. Plant Breed. Genet. Vol.(5): 317–327. Tanumihardjo, S., McCulley, I., Roh, R., Lopez - Ridaura,S., Palacious - Rojas,N. and Vellakumar, S.(2014). Introgression of low phytic acid locus (lpa2 - 2) into elite maize (Zea mays) inbred through marker Assisted backcross breeding. Aust. J Crop Sci., 8:1224 - 1231. ; Not Available
THE USE OF NATURALLY OCCURRING MOOD- altering substances is deeply rooted in the traditions and cultures of many communities worldwide. As documented in other societies and historical records,1,2 various compounds have been employed for altering consciousness and for their curative effects.3 Two substances traditionally used in the Middle East include hashish and khat.4 Hashish, as cannabis, has been known in the region since ancient times.5 Khat, also known as chat, derived from the leaves and young shoots of the khat plant (Catha edulis), is used for its stimulant effect.6 Technological advances that enable high purification of drugs and transporting them fast, and increasing urbanisation, have caused these mood altering substances to be taken out of their traditional role in societies and have come to pose new, complex and challenging threats.7 These threats have been manifested in two important ways: () wider use of drugs, and (2) a shift from natural drugs to the more potent purer forms. Globally, illegal money derived from illicit drug transactions amounts to 400 billion dollars annually, and is second only to the arms trade.8,9 The countries of the Arabian Gulf Co-operation Council (GCC) offers an interesting study area because their diverse cultures have experienced rapid acculturation, a phenomenon often equated with a rise in psychosocial stress.10 Psychosocial stress has often been associated with vulnerability to self poisoning11 and substance abuse.12 Although there are no adequate statistical studies to indicate the incidence of substance dependency in the GCC, it is clear that substance abuse is not a minor problem considering the number of reported drug seizures by the authorities.13 In real terms, the drugs seized by law enforcement authorities constitute only 5–0 percent of the actual quantity.14 Comprehensive data on the pattern of substance dependency is hampered by the criminal and moral stigma associated with substance dependency. Whatever the real number of people afflicted with addiction, substance dependency is a severe problem when considered in terms of personal distress, family disruption and interference with productivity and economic growth. Efforts have been undertaken in GCC countries to reduce the demand for drugs and to prevent drug abuse before it occurs. These efforts are coordinated through the Demand Reduction Committee, created in 200 with members from all countries of the GCC. The committee provides leadership in coordinating and facilitating strategies in this area including law enforcement, rehabilitation and leading and assisting the community in the task of education and prevention of substance abuse. Some studies have suggested that substance dependency occurs in adolescents in all strata of the society.14–16 However, these studies are limited to self-report questionnaires based on secondary school students. Although peer pressure is likely to play a significant part in the initiation of substance abuse,16 the subsequent heavy abuse is often associated with various psychosocial factors. It has been suggested that of all the social factors that predispose individuals to substance abuse, boredom is the most significant.14,17 The recent affluence and modernisation of the GCC societies have led many people to have a lot of spare time, as household chores are carried out by expatriate servants.14 The detrimental effects of such a lifestyle, including substance dependency, have been speculated in the literature.13,18–21 In a study cited by Al-Harthi14 of personality profiles and descriptive analyses of typical substance users enrolled in a treatment centre in Riyadh, Saudi Arabia, the most frequently stated reason for indulging in drugs was to escape boredom. This view, though substantiated by other studies in the region,22,23 has not taken into account the relationship of individual temperament to substance abuse. Recent studies have suggested that phenotypical "risk takers" or "sensation seekers" are often not inhibited from yielding to various illicit practices including substance abuse.24 Future studies in the region should examine the association between personality types, risk taking behaviour and boredom. The premise that the rise in substance dependency might be precipitated by erosion of traditional family networks and skewed social expectations might be relevant to GCC countries. Al-Hashmi18 has suggested that modernisation has resulted in the Omani family becoming nuclear at the cost of the traditional extended family. Concurrently, domestic servants brought from overseas, often illiterate in the dominant language, are providing much of the socialisation to children. Reinforced by frequent international travelling, satellite televisions and the Internet, acculturation appears to have occurred too quickly in GCC societies. Smith has remarked that these changes have brought these communities development that took a thousand years in Europe in less than 20 years.25 Studies from other parts of the world that have experienced similar rapid pace of modernisation have shown disintegration of native culture and identity as well as dissolution of the social network, to which individuals had previously turned for help when in trouble.26 In addition, the spread of education have resulted in higher levels of expectations. In the new social order, individuals in the region tend to regard employment opportunities, guaranteed higher levels of income, and especially, higher social standing, as acquired rights. Frustration of the desire to climb the social ladder leads to social insecurity.14 The present situation of society in transition fits with the classical sociological observations of Ibn Khaldun and Emile Durkheim: rapid transformation leads to breakdown of traditional social cohesion.14As a result, the sense of belonging becomes a luxury, leading to social drift, alienation, and the proliferation of social misfits. The society itself may become anomic. The relationship between acculturation, anomie and drug taking has received empirical support.27 The present tendency is to view substance abuse in its psychosocial context rather than on moral terms. While more studies that are comprehensive are needed to examine the pattern of use and misuse of drugs in the GCC countries, there are various reasons to assume that substance dependency is likely to continue to pose a problem in the region. First, the geography helps both trafficking and consumption. GCC countries are located close to the "Golden Triangle" or "Drug Belt", a part of Asia where underdevelopment and political instability have fuelled drug driven economies. Second, being on a major route for international airlines and sea routes by virtue of being in the middle of the world, GCC countries are at constant risk of being used as trans-shipment points for drug trafficking. The Arabian Peninsula has a vast coastline with its horizon overlooking major sea routes to different continents. Even if vigilance to guard its borders is heightened, such a long coastline would remain porous. Moreover, effective surveillance would require more allocation of resources and work force, drawing vital resources away from establishing essential remedial and rehabilitation services for the victims of substance abuse. Thirdly, the increasing number of visitors and the presence of foreign labour in the GCC also help make the "Gulf route" a crossroad for trans-world drug supplies. Some individuals may fall prey to the fallouts from these passing illegal shipments even though they may be destined elsewhere. It is also possible that an increase in consumption of illicit substances among the local population has in itself escalated the demand. In support of the latter view are the rising statistics on the mortality related to drug abuse and the number of clients seeking treatment in rehabilitation centres in the GCC states.15,28 Dispensing accurate information on issues related to substance abuse is a key component to fighting drug abuse. Studies are needed to illuminate the effect of substance dependency in the GGC countries as the mass media often tends to downplay the risks of drug use, or sometimes even glamorises it. Evidence is emerging on the personal consequences of substance dependency. Okasha, in the context of Egypt, has demonstrated that substance dependency is likely to lead to underachievement at school or work and exacerbate family stress, financial burdens and exposure to criminal activity.29 However, literature does not discern whether these social problems are the cause or the effect of the substance dependency. Substance dependency is often associated with psychiatric morbidity30 but it is not clear whether this is cause or effect. Karam et al in their report from Lebanon suggest a strong relationship between addiction to substances of abuse and psychiatric diagnoses.31 These authors further suggest that certain personality types often abuse specific substances. However, such a simplistic view appears to be merely reiterating the chicken-or-the-egg argument. Some authors have suggested that substance dependency is a form of self-medication, which implies that individuals with substance dependency have high levels of psychosocial distress and use illicit drugs in an attempt to alleviate their distress. This is relevant to the suggestion that some psychiatric symptoms may mimic withdrawal effects of chronic substance dependency and withdrawal symptomatology co-varies with cognitive and psychological functioning.32 In addition to psychiatric illness, substance dependency has been seen to increase the risk of adverse drug reactions. A well-known complication of substance dependency is the risk of transmission of human immunodeficiency virus and other infections.33 VISIBLE PATTERNS IN THE GCC The discovery of oil in the GCC has brought rapid modernisation as well as unprecedented material progress and economic security.34 Although GCC nationals, like other cultural groups in developing countries, are thought to have beliefs that protect them against developing substance dependency, such beliefs appear to be eroding with the rising tide of acculturation and economic restructuring. Demographic factors such as the preponderance of adolescents in the population will continue to elude those advocating demand reduction policies even if harsher penalties are decreed for traffickers and users. Approximately 60% of the population in the region are less than 20 years old.35 As reported elsewhere, 36 adolescents are prone to risk taking behaviour, a temperament that has been associated with developmental milestones including the underdevelopment of the orbital-frontal cortex.34 In GCC countries, the rate of juvenile delinquency has, in a span of 0 years, increased approximately by 400%. Unless the needs of such a large and important segment of society as its young people are addressed, this may present a demographic time-bomb with unpredictable social consequences. With a fast growing population, competitions for social and occupational roles are likely to be more intense, leaving many failed individuals behind. With such a demographic trend, it is likely that many individuals carry a greater risk of developing various adjustment difficulties including substance dependency.37 Data emanating from other developing countries suggest that drug peddlers tend to target the poor and the unemployed. Whereas substance dependency in other parts of the world is often associated with economic and social breakdown,38 no study has examined whether substance dependency in the GCC countries follows the same pattern.39 Preliminary observations in Oman suggest that there is relationship between unemployment and propensity for substance abuse.14 Interestingly, the study suggests that addiction to illicit drugs is likely to interfere with employment, often rendering some individuals to lose their jobs. In the midst of such conflicting views, further studies are needed to ascertain the conditions that trigger drug dependency in the community.40 While more information is needed in order to make an informed policy on substance dependency, there is some evidence pointing to which substances are widely abused in GCC countries. First, clinical reports suggest that solvent misuse is extensive although no formal studies have been conducted. Hafeiz41 has suggested that abuse of solvents often occurs in order to overcome the boredom of modern living. There is also increasing evidence to suggest that some of these agents cause mental disorders42 as well as neurological complications.43 The chemicals in question include glues, liquid shoe polish, deodoriser, petrol, cologne and insecticides.44,45 A special pattern of substance dependency associated with social deviancy and delinquency also involves a home-made mixture of dates and ointments as well as inhalation of intoxicating fumes derived from burning the wings of cockroaches and ants with volatile substances. Habitual inhaling of these substances is often associated with a failure to thrive.42 Secondly, inhaling smoke derived from nicotine based substances is now common in many GCC countries.46,47 Tobacco is often chewed, snuffed or smoked either in cigarettes or in sheesha. The latter (also known as hookah) is a smoking device, widely used in some communities of the Arabian Peninsula, to smoke jurak, a cooked tobacco-fruit mixture, and burnt by an electrical device or by charcoal. The produced smoke passes through the water at the base of the sheesha and then a long-tube before it is inhaled. Though most smokers consider sheesha less harmful to health than cigarette smoking,48 this has not been substantiated in regional studies.48,49 Experimental and clinical studies have found that nicotine, an active ingredient of both sheesha and cigarettes, not only triggers cardiovascular diseases, but also predisposes frequent users to various neuropsychiatric disorders.50 The question remains whether smoking triggers mental illness or people with mental illness are more likely to smoke.51 Pharmacological studies have unequivocally shown that nicotine is as addictive as other well-known psychoactive drugs such as cocaine and amphetamines.52 However, GCC countries have given a low priority to this a public health issue. Demand for nicotine has been falling in industrialised nations, 53 but a similar picture is not emerging from middle and low income countries. Cigarette companies are now targeting the developing world.53 Moreover, cigarette companies are manufacturing products of differing quality for sale in different markets. It has been shown that cigarettes of the same brand sold in developing countries have higher tar content than in the country of origin.54 Some studies have suggested that certain cigarettes are made from more potent, hence, more addictive, nicotine.53,55 As there is no known effective program to educate people about the dangers of smoking, prevention and smoking cessation appear to an unattainable goals. To compound the problem, some proponents of the "gateway phenomenon" suggest that smoking is a springboard to hard drugs such as cocaine and heroin, 56 though there is also evidence to contradict this view.57 The social problems precipitated by alcoholism have not yet been reported in the GCC countries though some reports suggest that drinking problems are proliferating.13,44,58 The World Health Organisation59 estimates that more then 5 million people are disabled because of alcohol use, making it the fourth leading cause of worldwide disability. Theobald has suggested that approximately 0% of alcohol consumers will at some time experience serious health problems related to their drinking habit.60 As many individuals are now facing the daily challenges of modern living and the pressures of modern life, alcohol abuse is thought to be one of the elusive antidotes to modern insecurity.17 Some recent findings suggest that individuals who have a high subjective level of insecurity in their lives are likely to abuse alcohol to ward of their psychosocial stress. Interestingly, people with such attributes have been seen to have refractory types of alcoholism.61 Alcohol syndromes such as delirium tremens and Korsakoff's psychosis are known to occur among people who consume it regularly.50 Persons at risk of drinking problems cannot be reliably identified in the population; therefore the pattern of drinking and its psychosocial correlates are indicated for the GCC countries. The bulk of the studies21,45,58 have focused solely on exploring the validity of research instruments on cross-cultural application of drinking attitude and behaviour. Little is known on the effect of alcohol repackaged as "cologne" available in some GCC countries.62,63 Colognes or ethyl alcohol-containing perfume and after-shave are sometimes ingested as an alcohol substitute.64 Relevant to this, it would be important to determine whether the availability of alcohol and other soft drugs deters people from going into narcotics that are more dangerous. One suggestion is that in those societies of GCC where there is a relaxed attitude towards alcohol, there are fewer propensities towards heroin and other dangerous drugs.14 It also not clear how such information would be helpful in planning intervention programs in GCC countries, as the experiences from other societies suggest a complex relationship between alcohol and substance abuse. The "gateway theory" would suggest that using alcohol leads people to use harder drugs like cocaine and heroin.65 There is also scant information on the pattern and psychosocial correlates of over-the-counter medications in the GCC countries. Though generally viewed as harmless, many of them have the potential for abuse, particular those that are considered to be amphetamine-like stimulants.66 These includes nasal decongestants, bronchodilators, appetite suppressants and energy pills and drinks. While there is no evidence to suggest that cocaine and hallucinogens are widely consumed in the GCC countries, 13 the story of opiate use is somewhat different. Historical documents suggest that opium was considered as a medicinal substance in the Middle East. It was recommended by various towering Arab figures such as Ibn Sina.1 More recently, however, its semi-synthetic counterpart, heroin, far removed from its cultural context, is becoming the drug of choice for addicts in the GCC countries. Being close to heroin producing regions of the world, GCC appears to be the trafficker's place of choice. Being capable of causing compulsive dependency within a short time, heroin has a devastating effect on the user and society in general. To those who are addicted to heroin, it appears the habit leaves them little time for meaningful life. To compound the problem, as 90% of GCC heroin addicts use it intravenously, sharing of contaminated needles causes infections of human immune deficiency virus and a high incidence of other infections.33 Similarly, the number of cases of heroin addiction is often directly related to the number of crimes.27 Despite stringent regulations to reduce the supply and demand, the habit proliferates. Judging from the quantities of drugs seized by the authorities, the last decade has witnessed a dramatic increase in the number of cases of heroin addiction, the number of addicts seeking rehabilitation, and death due to heroin overdose.PROSPECTS FOR THE FUTURE Rehabilitation for addiction is often in the hands of psychiatric or penitentiary services though some specialised centres have emerged in some GCC countries.16 Culturally sensitive interventions seem to be often relegated to fringe importance. Medical interventions are likely to grow considering the many claims about new pharmacological tools that take advantage of the chemical properties of alcohol and other drugs. However, drug treatment for substance dependency should not hold up the search for psychosocial predisposing factors, which, in turn, could be a springboard for educational strategies to reduce demand. Indeed, blind adherence to pharmacological intervention not only seems similar to drug peddling, but also may be counterproductive in the long term. A biomedical explanatory model of substance dependency may lead to stigma, and lessen the individual and societal accountability in tackling compulsive dependency. Stressing personal responsibility, on the other hand, motivates one to change, as well as help one understand the challenges ahead and evolve coping mechanisms.67 As distress and stress are experienced in a socio-cultural context, rehabilitation services should avoid committing what Kleinman has called a "category fallacy", where a view of human nature developed for one cultural group is uncritically applied to members of another group for whom its validity has not been established.68 According to Kleinman, this results in a "distortion of pathology" rather than a critical understanding of the ways in which the members of a different cultural group perceive, experience and communicates beliefs and distress. One of the essential grounds for formulating enlightened policies toward drug dependency is to consider the society's outlook towards mood altering substances. Despite the documented frequency of substance abuse in GCC countries, a review of the literature reveals no objective studies on knowledge, attitude and perception. Opinion towards substance dependency among citizens of GCC countries is likely to have a wide-ranging influence, affecting issues as diverse as personal consequences of substance dependency, prevention, care and management of people with substance abuse. Historical and cross-cultural studies have suggested that individuals with substance dependence are likely to encounter active discrimination and harassment which, in turn, exacerbates their psychosocial predicament and perpetuates their relapse into drug taking.37 Similarly, it has been suggested that social attitudes can be more devastating than the addiction itself, and the addict's family suffers as well.69 Although many victims of substance dependency could benefit from treatment, attitudes of society towards them is likely to hamper their seeking rehabilitation. As a result, many are likely to stay underground until addiction has reached an advanced stage of irreversible pathology. This not only increases pessimism of the victims and those around them but also shatters the prospect of recovery. Therefore, more research in GCC countries should be conducted in order to shed light on socio-cultural factors that precipitate individuals to succumb to substance abuse. This would open the door for contemplating strategies to achieve a reasonable level of prevention as well as to prioritise which aspects of services are pertinent to the region. Grinspoon and Bakalar have suggested that of all the mistakes repeated, the most serious is trying to free society of drugs via legislation and regulation.70 Indeed, many studies1 suggest that no punitive measure deters availability and abuse of drugs.14 It appears that financial gain is one of the strongest determining factors. Globally, though consensus from the experts in the field suggests that substance dependency is a disease, public opinion often considers it a form of moral degeneracy that can destroy social values. As a result, victims of substance dependency are sent to the prison. Many countries have pursued the idea of creating a national consensus towards zero tolerance for substance abuse and death penalty for drug traffickers. The policies fluctuate between curbing trafficking, reducing demand and decriminalisation of certain classes of drugs.71 Some countries have considered decriminalizing soft drugs and the debate continues on the rationale of dispensing heroin to heroin-addicts.72 Although more time is needed to assess the long-term outcome of these new programs, history has shown that none of the previous campaigns to curb the spread of substance misuse has worked. Instead, the situation appears to be summed up in Bob Marley's lyric, "So you think you have found the solution; But it's just another illusion". CONCLUSION The problem of drug abuse in the GCC is a multi-dimensional one without easy solutions. This paper has touched upon several of these issues. Even though for zero tolerance to substance dependency is advocated, no program has been found to be universally successful in reducing drug dependence. Historically, many societies have tried both criminalisation and decriminalisation but to no avail. Despite all the technologies to monitor and legal authority to bring the drug traffickers to justice,including the threat of death penalty, dealing with substances that cause addiction is becoming a global challenge of ever increasing magnitude. More discouraging, the problem has even affected societies where one would expect cultural factors to protect them from the attraction of drugs. The purpose of this paper, thus, is to "point a finger to the moon", the moon symbolising the complexity of substance dependency. One should not confuse the moon with the finger that points to it.