Part two of an interview with Julia Casey. Topics include: Food that was purchased and prepared when Julia was growing up. Formalities between the Italians in her neighborhood. How the children would play. The Roxbury neighborhood house that started a girls club and the types of activities they participated in. The nurses and doctors who would visit the neighborhood. Home remedies for sickness. How Julia and her husband met. How their marriage was received by their families. What it means to be Italian. Julia did not grow up in a religious community. What it was like to move to Fitchburg from Boston. The different expectations of boys and girls in Julia's family. Julia's children and their jobs. How speaking proper Italian has benefited Julia. ; 1 JULIA: In, in these little -- I mean, they still have the same candleholders. I've got them on my dining room table, but, but they didn't have -- I don't remember the candles. I remember these little wicks. I'm gonna ask my friend about that. And they would float on top, and you would think it would be kind of dangerous, wouldn't you? But I still remember these little candles they would keep bringing. Now, that was one of the customs, but they have special foods on the 19th of March. It was I think the Feast of St. Joseph, if I'm not mistaken. INTERVIEWER: Yeah, it is. Mm-hmm. JULIA: And the lady across the street would make that little Italian pasta they called orzo, and I think it was a type of barley. They would make the actual grain itself and the orzo pasta, O-R-Z-O—you can buy it in any market today—it was shaped like that. But they would make a dish from, I think, I think it might've been barley, and they made that on the Feast of St. Joseph. That was the custom where they came from. INTERVIEWER: Did they also make -- I don't remember what it's called -- but fried dough, little pizzas? JULIA: No, that was not, not common. I didn't know any -- no, and we didn't eat pizza, not like they do today. I know that my father, there was a barroom about a mile away from us, an Italian barroom in another Italian section, and that then made pizzas. And very, very seldom did I ever know of anyone who made pizza. You know, one of the ways that they did was they used to dip bread in tomato sauce, which is all pizza is, but I never actually knew families who made pizza. That didn't come into fashion until long after the war. INTERVIEWER: So living with all of these different people, no one really made pizzas? JULIA: No, no one made pizza that I knew of, you know.2 INTERVIEWER: Mm-hmm. JULIA: And nobody made lasagna. And raviolis, very seldom did anybody make raviolis. Why, I remember that in the [Piedmontese] family they would make these very fine Italian sausages with white wine, you know. Some of them made bread, but it was a problem because the bread man from the Italian, the big Italian bakeries in Boston, would come through the street. We -- they went out shopping but they went out mostly to buy different kinds of meat and specialties. But we had food then, clocks with fresh food, fish. The chicken man came, vegetable man came through the streets, and the women would just buy what they needed right on the street. On Saturdays they'd go shop; everybody went out with bags. They'd go into downtown Boston and buy special things that they, you know, couldn't get, but for the most part they went shopping once a week. They would go to their special stores to buy, you know, different kinds of spaghetti and pasta. They used to buy them in big boxes, some of the families, 10, 20-pound boxes of fine -- long, long spaghetti. And they didn't have the varieties that they have now, you know, but I mean, if they wanted salamis they'd have to go to the Italian delicatessens where they sold the different kinds of salami and everybody ate different kinds, you know. My father would go in and bring home these packages. The markets -- we went to the -- in the north, and with Petrini and Baldini, and they would slice the salami paper-thin and they'd weigh it out on gorgeous pieces of wax paper in beautiful, even rolls, every kind all rolled up. You know, he'd bring them home and we'd go crazy. Italian bread and salami, those are our idea of living, prosciutto, you know, salame crudo, salame cotto, [unintelligible - 00:05:11]. And they used to make -- my mother made lintels with a special, big liver sausage and other kinds of, 3 you know, pork sausage, and that was a dish that they had once in a while. So the food was very -- it was, whatever house you went into there was a different tradition. Every region had different… INTERVIEWER: Was there a lot of sharing? JULIA: No. I wouldn't say that, no. There was -- they maintained, really, a great deal of respect and formality. You know my mother lived with these families, 13, 18, 20 years, she would never think of going downstairs without, you know, knocking on the door and saying permesso when someone answered. You always said permesso before you entered. INTERVIEWER: Mm-hmm. JULIA: She -- and they referred to each other as signora. They didn't call each other by their first names for many, many, many years, you know. INTERVIEWER: Even with the… JULIA: Unless they were said, unless you were told, you know, "Call me Angelina," "Call me Celestina." They knew the first names, but they really observed quite a formality. INTERVIEWER: Is that among people even in the same region, from…? JULIA: No, if they were from the same region, you know, then they would call each other that, that way. But from another area, until they got to really know each other, quite a while, you know. They -- some of the southern Italians worked in stitching shops. We had a family who had a pants -- he was in manufactured pants, and various of his women relatives and men relatives were in downtown Boston, you know. Most of them did well; they were frugal people. Their children bought automobiles, very few of the originals, you know, immigrants, bought any. So we had a kind of a clear street for playing. That's why we were able to play jump rope and hoist the 4 green sail and red rover and hide and seek. We played all these games on the street. The girls who were a little bit older than we were, they'd come out of the laundries, and if we'd be playing double-dutch jump rope, they'd come and swing -- we're talking long clotheslines -- swinging long clotheslines in the street, double-dutch, you know. Now, I think only the black girls do it, very complicated. INTERVIEWER: Yeah, the cities. I think it's popular in the cities still. JULIA: Yeah. Well, now you have too many cars. You don't have any clear spaces to play things like that. The boys made -- what do they call them, I don't know, scooters out of roller skates of two by fours on orange crates [laughter] and go whizzing along the street with these homemade things, you know. INTERVIEWER: Did the girls ever do that? Do they ever borrow these scooters? JULIA: No, we were, we were not tomboys. As I said, our mothers kept an eye on us, and they would play stickball, the boys. We would play catch, among the girls. But -- and we belonged to a settlement house, a bunch of us did, and they took us to camp… INTERVIEWER: Was there any…? JULIA: In fact, I still have a picture of a group of us. INTERVIEWER: The settlement house, was there any…? JULIA: The Roxbury neighborhood house on Albany Street, which was there for, maybe, 50, 75 years. Its special work was to help the immigrants integrate into American ways of society, and they provided clubs. Somebody came to our street and started up a library, a girls' club, and as a result of that group -- and it was one of the Boston's Brahm-, a woman from the Boston Brahmin family who, you know, belonged to -- this was their way of doing social work, women that were brought up very well-educated in the Back Bay or Beacon Hill area of Boston, belonged to these old families 5 whose, many of whose ancestors had made their money on merchant ships, you know. And that was one of the works that they did. And they take to our street, and the street next to ours, and they started a girls' club. They would bring books, and we learned to do a little crafts, knitting, and then eventually, we joined the neighborhood house and they had a camp in Bennington, New Hampshire, to which we went, and they would take us to wealthy homes for once a year, say, for picnics out in the country. And then at the neighborhood house, we put on plays. I remember one time we went to Simmons College, and a group of us put on a play, Little Lord Fauntleroy. One of us had a green velvet costume, put it on for the students, and then we danced, and we talked about different things. And as I said, we did some crafts and they encouraged whatever they saw, for instance, they -- I liked classical music. I don't know why because, you know, I mean, in that generation very few people had pianos—but they did have phonographs, you know. We didn't. But somehow I was attracted to classical music and I was able to get tickets to the youth concerts at Symphony Hall through the neighborhood house. And it was wonderful, you know. In fact, the girls that grew up after us did the same thing. They belonged to the neighborhood house and had their own little group. INTERVIEWER: Now, is this a place that really catered to the Italians? JULIA: No, it catered to -- Roxbury was sort of in the area, there were a lot of Italians there, but it didn't cater to them especially. There were people, you know, from other groups and this -- the odd part was that our neighborhood was not connected to any other neighborhood. It was isolated; that's what made it so close. Many of the young people that grew up there married each other. That's one of the reasons that the families maintained contacts, you know. 6 A number of people that I knew married other people from the neighborhood, and so from one, you would hear the news of what's going on with others even though they lived in faraway suburbs through those family connections. INTERVIEWER: Mm-hmm. JULIA: But we didn't interact with other Italian neighborhoods at all. We had this industrial area that we had a big playground that the kids on my street didn't use very well, and it was right next to our elementary school. But our families would never let us go to these industrial areas in the afternoon or night; that's why we were confined to our streets. INTERVIEWER: And that's where you'd play. JULIA: Right. INTERVIEWER: So when you were part of the Roxbury neighborhood house, was that your first exposure, really, to other ethnic groups? JULIA: But we stayed together; the girls from my street stayed together in their own group, and we did not interact unless we were -- and we put on our own little plays. Oh, we put on a supper one night for the staff of the neighborhood house, the head of it. Dear God, what was her name? Her brother was a very, a world-famous Shakespearean actor. I can still see him now—tall and thin, with great refinement. These women were all college graduates. Some of them had gone to the Simmons School of Social Work. At that time that was a very important area of study. You know, at the house in Chicago, these women became -- well, it was called social workers but not the same way as they do in the Welfare Department. This was real social work. And the house was an offshoot of the settlement house movement that started with our house in Chicago. They had them all over the east, eastern part of the country, you know, so they'd seen all 7 different kinds of ethnic groups. But they were very refined women. They taught piano, they taught music, and they had a library. They got college girls to come in and help tutor students who wanted to be tutored. They provided many services. They went out into the neighborhoods. And they, along with our elementary school nurse, provided wonderful medical services for those neighborhoods. My sister, who was born two years after I was—I said she was my brother's twin—was very seriously brain-damaged, and the result of that was that, you know, my mother's life was pretty terrible for the -- until she died, she was a serious epileptic, at ten. INTERVIEWER: She was epileptic until she was ten? Is that it? JULIA: She died when she was eleven. INTERVIEWER: Old enough. JULIA: At the age of ten, when she was about ten or eleven, my mother found herself pregnant with my youngest sister. And the visiting nurses used to come to the street, whom I think, it might've been through the Metropolitan Insurance Company. They would come in their blue uniforms, and they would visit all these Italian women who had any need for any kind of medical service. If one of them was pregnant, she came and spoke to you and advised you how to take care of yourself. She did the prenatal work. You didn't go to the hospital or a doctor if she advised you, but she did notify the hospital of when the birth was expected. INTERVIEWER: Mm-hmm. JULIA: But she gave you, you know, information on good health and hygiene and what you needed to eat. Because the Italian women, they were naturals at this, except my mother, who had grown up in a family that was extremely reserved and she knew absolutely nothing when she came. You know, they didn't -- you grew up in Italian families in rural areas, then you, knew because they taught. 8 And, in fact, my mother even had a midwife, one of them had midwives who were… they were trained in folk medicine, you know. They weren't like the [unintelligible - 00:18:09]. That was why some of the births were pretty bad. INTERVIEWER: Oh. JULIA: But anyway, they would help each other by, you know, in that way, but they -- the visiting nurses and the school nurse. The school nurse, if she detected a problem with any student in the school, either from information by the teachers or -- we also had physical examinations, and doctors would come in once a year, and physically examine every child. She detected vision problems. If they detected anything, like they would catch phases of diabetes, they would catch all kinds of problems. The visiting nurse would immediately visit that child's family, and she would make the arrangements to have the child sent for examinations at Boston City Mass General, wherever there was specialists for whatever they saw, you went. Once a year you brought five cents, a bus would pull up to the school in relays, and everybody went to the dentist in Forsyth Clinic. For five cents, they did pulling and filling, and this is where the dentists were trained, so the student dentists would take care of you. INTERVIEWER: Do you feel that the settlement house then had changed your life in any way? JULIA: Oh, definitely. You know what? It performed wonderful services. In the first place it taught us, it taught -- besides the playing that we did on the street, it brought us into a little bit more of the American way, you know. It brought a little more cohesion, and we learned to do things that we couldn't have learned on our own. Although, on our street they used to put on, like, shows, so we'd dance in -- strictly amateur, and one of the mothers made crepe 9 paper costumes. She could run them up so rapidly, I could still remember this purple crepe dress that was [laughter] with ruffles and a [unintelligible - 00:20:43] here, a ruffles on the skirt, and I still keep in touch with her daughter. INTERVIEWER: Wow. JULIA: They were clever. This lady would go into the stores and see something in the window, a dress. And she'd fix it in her mind and come home and cut out a pattern out of newspapers from what she remembered, and she would produce dresses for her daughters. INTERVIEWER: So it exposed you more to an American way of life? JULIA: Yeah, it did. And you know, besides our old school teachers, they spoke beautiful English. INTERVIEWER: Were you going to school with mostly Italians? JULIA: Yeah. INTERVIEWER: Only Italians, or…? JULIA: Well, I would say a lot. The Irish had more or less moved away from that section of Roxbury, even though our parish church was St. Patrick, and the Irish had moved well up beyond Dudley Street because they were by that time much more affluent. INTERVIEWER: Mm-hmm. But it sounds like the neighborhood that you grew up in was so harmonious. JULIA: Yeah. INTERVIEWER: Did you ever feel any sense of conflict when you went to school or outside the confines of the neighborhood? JULIA: We did. We felt that, so there must've been a lot of what we used to refer to as American kids, who are probably mostly Irish descent. But we didn't have very -- we had hardly anything to do with them at all. There was one Irish family, the Kellys, and they went to parochial school, but actually they married into the Italian community. And that was the only Irish family I knew. INTERVIEWER: Mm-hmm.10 JULIA: My father had a few Irish tenants who we didn't think too much of. Going to the Depression they would never pay their rents, you know, but then… INTERVIEWER: In that six-family house that your father owned, were there other relatives living in the house? JULIA: No. INTERVIEWER: No? JULIA: No. There were, you know, strange people who came. And during the Depression men sold wine, you know. In fact, even during Prohibition some of them did. We would find taxis coming into the street, and I don't know how people got, you know, the names of people who would sell the wine but if you had no money, or very little money, you made money any way you could, you know. INTERVIEWER: Mm-hmm. JULIA: So. INTERVIEWER: So what about the other families from different regions? Would you call them by regions? JULIA: They were very -- they were, yeah. INTERVIEWER: I heard… JULIA: Calabrese, Baresi, Sicilian, yeah. INTERVIEWER: But when you referred to them I heard you just mentioned a little while ago that… JULIA: Yeah, Piedmontese. We had about four or five Piedmontese family. And of course, their dialect was even different. And that's next to Lombardi, but see, their dialect takes from the [unintelligible - 00:23:56]. INTERVIEWER: Oh, I see. JULIA: Right. INTERVIEWER: And where does yours? JULIA: More, you know, we -- down to the east of Lombardi is the Venetian province, and then you go up into the Tyrol, which today 11 is bordered by Austria. So the northern Italians, they don't put final vowels on their words. They chop it off, you know. INTERVIEWER: Yeah. So I was -- I've been noticing your pretty green eyes. Where did you get those? JULIA: All Italians have their, you know, you'll -- there's a brown-eyed type, but you can find green-eyed Italians in Sicily. INTERVIEWER: Really? JULIA: Oh, yes. Hazel, you know. INTERVIEWER: Mm-hmm. JULIA: Grey from my mother and father. They didn't have brown eyes. Nobody in my family had brown eyes. INTERVIEWER: Hmm. Wandering in your neighborhood, was there a woman that people would go to for advice, or…? JULIA: On the next street there was a lady who apparently had been, you know -- there were many ways to educate people, have always have been. And some people were very wise. She was in America a lot longer than the other women. She had a big family with grown, with grown-up sons, so she was -- and she came from a family where she was told a great many things and learned many things. So yes, there were some women who knew about things, but since they all came from different regions they all knew their own customs, and they had different ways of treating, you know, headaches, or -- I remember my grandmother used to slice potatoes and put them inside wrapped, fold them into a cloth, and when somebody had a headache, my aunt did that, too. They would put these sacks of potatoes in this cloth; they would just tie the cloth and bath with them. I don't know why. They used to string garlic if they thought a child had worms, and a child would wear this string of garlic around his neck. And if you had a boil, my mother would cook linseed flower. They'd buy them in the drugstore, only in the Italian drugstore, and you would 12 make poultice—that was very common. Some people used bread and water, and you would have this thing on whatever bump you had that you wanted to [unintelligible - 00:26:47]. They were really strep infections, but they didn't know strep infections, you know. There were boils, and if you have a little infection in your finger or thumb, you'd wrap it up in bread and water with a bandage or poultice of some kind. Even the American doctors would recommend them. They'd tell you, you got -- check moisture and heat would cause these things to mature. INTERVIEWER: Did you notice that different regions…? JULIA: They would bring chamomile -- yes, Mrs. Mucci downstairs kept herbs, dried herbs, chamomile and what they referred to in America as mallow [unintelligible - 00:27:41] and I -- if that [unintelligible - 00:27:44] grew here, I had a plant one time. And they would buy these dried herbs at the Italian drugstores, and they would make teas out of them. You would drink them. If you had indigestion, the northern Italians would buy it in liquor stores. It was called Fernet, F-e-r-n-e-t. It's actually an [unintelligible - 00:28:10] in medicine containing a great deal of -- bitter, bitter! But many times you'd go visiting in, after you wake, sometimes before, you would get a tiny glass of Fernet. Branca – that was the trademark. It came in a green bottle. And it was co-, it was a digestive. It was -- because it was so bitter, it was considered to be good for your stomach. INTERVIEWER: So no matter what your age, you would get that? JULIA: Then we -- everybody had Belowski. INTERVIEWER: What's that? JULIA: May I give you either some hot tea or coffee? You must be exhausted. INTERVIEWER: No, I'm fine. I'm fine. It's not much longer. Thank you. JULIA: And get you as hot as broth, or as a broth.13 INTERVIEWER: No, I'm fine. Do you need something? JULIA: I get like this once in a while. But yes, I don't wanna move this thing. INTERVIEWER: I can take it off if you'd like. JULIA: I find the only thing is -- part of the [unintelligible - 00:29:15]. Five months ago he's a co-host by the senior -- high-styled program on FA-TV, so we call him the Mike Wallace… INTERVIEWER: And you've been married [unintelligible - 00:29:32] years? JULIA: [Unintelligible - 00:29:32], Linda. Linda! [Unintelligible - 00:29:35] HUSBAND: Oh, pardon my cold hand. JULIA: That's my husband, Phil. INTERVIEWER: Nice to meet you. HUSBAND: My pleasure. JULIA: In his museum of … in New… museum about neckties that I paid a fortune for. HUSBAND: Well, I sure got TV exposure today. JULIA: Yeah. He get to… who did you interview today? HUSBAND: I interviewed a very interesting 91-year old woodcarver. JULIA: Oh, my heavens. HUSBAND: Louis [Charpentier]. And then that was followed up by a group of Irish step dancers. And I didn't do anything on that, so they just dragged me from dancing, so all I could do was say, hello and goodbye. INTERVIEWER: Oh. HUSBAND: It was frustrating. JULIA: You know, Edcel Johnson wants you to let him know when that program is on now. HUSBAND: Oh, I'd bet they… JULIA: Teddy, too.14 HUSBAND: I bet -- all right. I bet they did that thing so I -- in my notebook there. INTERVIEWER: Was it a cable TV show? JULIA: Yes. It's at ATV. You know, the informational video… HUSBAND: It started innocently enough. I'm on the board for an organization called The Resources for the Elderly, and their primary function is to sponsor the Meals, Meals on Wheels and the Elderly Nutrition Program. Like they some -- it goes back about three, four years ago. It's been quite a while. They started this program—these are all volunteers and all seniors—it's called Senior Lifestyles. And as a TV show material that is supposedly of interest to the seniors, and it, it's partly information and partly entertainment. And so, as I say, I'm on the board for the Resources, and we were having a board meeting, and it just so happened that the woman who was then serving as host for the program for some time decided that that was enough for her, so they're looking for somebody to fill in as a host for the TV show. And one of the board members [woke] up and said, "Mr. Casey would be a good replacement." And somebody else said, "Yes, indeed. He would be great." JULIA: Oh, he loves women. HUSBAND: And I couldn't think of any reason why I couldn't or wouldn't do it, so before I knew it I had been drafted and I was serving as host to it. Then that's what I do. It's on once a month, and they have two half-hour segments. Usually last -- monthly only has one half-hour, but today we have two half-hour segments, and the first one was this Louis Charpentier. And my god, he was -- you know that guy we saw in the coffee shop? JULIA: I thought he was gonna be easy… HUSBAND: No, no, no. This is… JULIA: … interviewing famous carpenter. Oh, Louis Charpentier.15 HUSBAND: … this Louis, he is -- he claims to be 91 years old. JULIA: Oh, my heavens. INTERVIEWER: He looks wonderful. He does. JULIA: Did you see any of his work? INTERVIEWER: No. HUSBAND: I used to… JULIA: I think they have it at the library? HUSBAND: He used to be head of the plastics industry. And the plastics industry was an organization, apparently, that did work for all of the plastic shops in and around… JULIA: When you came with your ham sandwich a little mustardy. INTERVIEWER: I thought… JULIA: I thought you'd have sandwich. You've got to listen to me talk for four hours and have nothing. HUSBAND: Yeah. I'll have a ham sandwich. INTERVIEWER: Well, you have to get those though, because you said you had to wait… HUSBAND: Oh, that's all right. JULIA: I'm gonna call the lady and tell them you're gonna be a little late. HUSBAND: But anywho, this Louis is something else, and he was -- he started his woodcarving when he was only about two years old, apparently, while he had a carving that sold his home up to the farm up in -- well, back and around or back there, and there was the oxen that was plowing, there was his father, there was the house he lived in and his school, the whole bit. INTERVIEWER: So do you interview these people? HUSBAND: I interview them. I try to make intelligent conversation with them. JULIA: I have made intelligent conversations with them. HUSBAND: The thing that makes this fascinating is that I usually don't know until I arrived at the studio who is going to be the guest for the day. INTERVIEWER: Oh, that's difficult.16 HUSBAND: I have to -- I know it was… INTERVIEWER: Oh, Julia was just telling me about the tapes that you found in the [unintelligible - 00:34:30]. HUSBAND: Yes. INTERVIEWER: That's remarkable, especially because here I am two days later. JULIA: I know. INTERVIEWER: All about Italian dinner. JULIA: And on the other tape, what I said -- think it's a, seems to be a little illogical, I was wanting to say the least. In the other tape, you would have to guess who the family Christmas but then I'd read, since I wrote it all out, it's more logical, you know. It's more -- or less of a timely sequence. But I do give you the information I've given you about the broth. INTERVIEWER: Okay. JULIA: And… INTERVIEWER: It'll be interesting to make a… JULIA: Oh, yeah. I'm gonna make myself a sandwich if I can figure out how to open this slice of cheese. INTERVIEWER: Do you want some help? JULIA: Oh, I -- oh, here it is. Heavens! I thought. What's the matter with this? INTERVIEWER: How does your husband feel marrying an Italian? JULIA: It was an adjustment; let us put it that way. INTERVIEWER: Was it? JULIA: I met him… thank you for this. INTERVIEWER: Yes. HUSBAND: Tried one this morning. INTERVIEWER: Oh. So who made these? HUSBAND: The man I interviewed, Louis Charpentier. INTERVIEWER: Oh.17 JULIA: Oh, he gives you -- oh, I've seen him do that at the Historical Society where he teaches you how he got started. HUSBAND: Right. JULIA: And he tries to teach everybody that they can do the same thing. INTERVIEWER: Oh, so he was -- his work is just so good. Oh, he's so… HUSBAND: No, he used to work in plastic. And as I say, he works for -- he works in an organization that designed methods for making just about anything you wanted, buttons or, how do you say, [unintelligible - 00:36:18] or whatever it was called for… JULIA: I know he's just working now. He's in the library and… HUSBAND: No, no. He's retired. JULIA: Yeah. But where is his work? I know he started, he started on display somewhere. HUSBAND: Yes. It's in a home. He has it at home, because I asked him if it was all insured and he said that it was. JULIA: I don't know how… INTERVIEWER: So Phil, let me ask you, how did you feel marrying an Italian? HUSBAND: Oh, wow, it… JULIA: You should ask his mother. HUSBAND: No, we -- and now seriously, we had a problem. It's not because I married an Italian, no. It's just that my mother didn't particularly like Julia, unfortunately. I'm not sure what the root of her prejudice was. It might have been because of her heritage, or it might have been just because my mother didn't want me to get married at that point, although I was not exactly a teenager. I had come home from the war, and I was a book. But whatever reason or reasons my mother had she didn't actually… didn't actually -- she didn't oppose the marriage, but she didn't support it, and she didn't even show up for it. My father and my sister came. JULIA: Though she was my [unintelligible - 00:37:48], she cooked. She was great to the children.18 HUSBAND: Oh, yeah. That's right. She loved the, she loved her grandchildren. She was very -- and they had a great time. JULIA: She was very generous to me in many ways. HUSBAND: My son approved of Grandma's cooking, and they had a good time visiting her. And we all, every holiday, we make sure that there was a delegation that went to Grandma, though we tried and made a compromise. INTERVIEWER: Mm-hmm. Now, did you -- where did you grow up? HUSBAND: I grew up in Roxbury prior to the days when Roxbury had the… with the ethnic… JULIA: Now it is. HUSBAND: It is now. When I was -- I was there prior to that. INTERVIEWER: Thank you. JULIA: Lemon juice? INTERVIEWER: Thank you. HUSBAND: And by one of those strange coincidences, Julia lived the one part of Roxbury, I was in another. We had never laid eyes on each other before the war. Did she tell you about how…? INTERVIEWER: No. I don't know how you met. No. HUSBAND: Well, we met -- it was like something out of one of those [unintelligible - 00:39:12] that tells -- she had that series of how people tell how they -- I was in the Navy during World War II in an organization called the [CVs], and I was stationed overseas in New Guinea. I met her brother, who was in the combat engineers, and there was this [unintelligible - 00:39:37]. So I got to know him, and his platoon was involved in the invasion of the Philippines. They were moving out agents. So he said to me, he said, "Phil," he said, "we're going to be cut off from correspondence for a while. Would you do me a big favor and write to my mother and tell her that if you don't hear from me, not to worry, I'm all right?" So I said, "Sure, all right." And I did 19 that, I wrote to his mother, and his mother who was living in Roxbury, I sent a letter to Washington where my girlfriend was thankfully employed as a government girl. And I -- with instructions for her to answer this letter. So she answered the letter, and Julia and I started corresponding, and that's how we get to know each… JULIA: Fifteen months. HUSBAND: And then after the war, when I came home, I… JULIA: It was all over. HUSBAND: And then there… INTERVIEWER: What? What was all over? JULIA: It was all over. He was hooked. INTERVIEWER: Oh, he was flirting as soon as he saw you. HUSBAND: Then there was some kind of a breakdown in the romance, and we had separated. [Unintelligible - 00:41:00] and we get back together again and we could get married in 19… INTERVIEWER: How did her parents feel about her marrying an Irishman? HUSBAND: Oh, as far as I know… JULIA: Horrible. HUSBAND: Yeah. INTERVIEWER: Oh, with him? JULIA: My father… HUSBAND: There was a point in time when her father didn't care who she marries and who would take her off his hands. INTERVIEWER: Oh. JULIA: I was going to [unintelligible - 00:41:24]. HUSBAND: Yeah. I was even supposed to get a bicycle, a motorcycle for marrying her. JULIA: "Philly, I give you motorcycle [unintelligible - 00:41:34]." HUSBAND: No, but she… JULIA: You better [unintelligible - 00:41:38]20 HUSBAND: Neither one of those gifts materialized so, anyhow. No, I liked her father and mother. And of course, I had -- I was very friendly with her brother and sister. And so, we had the wedding, and that was a [unintelligible - 00:41:57] together. INTERVIEWER: How was she different from the, let's say, Irish girls that you went to school with? HUSBAND: Oh, she was a different. -- I didn't actually – I didn't know that many girls when I was going to school because you have to remember that when I was going to school, this was in the days when the boys went to one school and the girls went to another. Boy's school was an English high school. JULIA: But in elementary school… HUSBAND: Elementary was all boys because of… JULIA: Oh, you did? HUSBAND: Yeah. That's -- I went to the all… JULIA: Oh, I didn't know that. HUSBAND: With the nuns [unintelligible - 00:42:34]. JULIA: Well, I was actually the first female person you ever met. HUSBAND: No, not exactly. I met… JULIA: You may have seen New Guinea. HUSBAND: You have to define, there, the word "met." Kind of -- you were the first female that I was—let's put it this way—that I little became involved with. JULIA: Well. No. That's enough. INTERVIEWER: Well, we're in all kinds of things today. JULIA: Are you gonna have a ham sandwich? HUSBAND: Yes. I'll have a ham sandwich. So what is this project here? INTERVIEWER: This is a project that's recording the experiences of -- by Italian-American family in the Fitchburg and Leominster area. HUSBAND: Oh, yes.21 INTERVIEWER: But we had seen Julia at a -- one of the Italian night, the films that Fitchburg State College had put on, and Julia started talking extensively after the movie, Big Night, I think it was called Big Night. HUSBAND: Yes. INTERVIEWER: And we realized it was someone that maybe we'd like to talk to because she seems to know so much about the culture. HUSBAND: Yeah. And she is the one member of her family that has -- that is interested in the [unintelligible - 00:43:57] of the family extensively. JULIA: I was also the first one born in this country of my family. INTERVIEWER: Your family. HUSBAND: She was born in this country, which makes her an Italian-American, but she maintained contact, through her mother, maintained contact with Italy. She knows how to speak Italian, including the dialects of northern Italy. And now she is in the process of learning how to speak… INTERVIEWER: Right. HUSBAND: She's starting again. Yeah. INTERVIEWER: Now, were there any surprises though when you married…? JULIA: Yeah. Seven. INTERVIEWER: That's -- wow. Seven children, right. But the Italian culture, I'm wondering… HUSBAND: No, I didn't have any problem with that. I was very fond of her family. Wherever her family gathered then there was a party. And her family had always been most cordial to me. INTERVIEWER: What do your children consider themselves? HUSBAND: They consider -- when they think about it, they… you probably have to ask them how much they consider themselves to be Italian. JULIA: More than half. HUSBAND: Well, I don't know whether they really think about it.22 JULIA: They went to the parochial school in Dorchester, and their last name was Casey. So they fit right in. Even though there were a lot of Italians. And by this time, Dad is gone. You know, we're not immigrants anymore. Your father was a professional man who's a graduate of Boston College, and so that they didn't have to go through that. They… HUSBAND: I came up here; this is the first place I've ever been to where they couldn't spell Casey. They would actually went, "Case-, how do you spell that?' And I thought at first they were kidding me, because down in the Boston area there was a very large population of Irish-Americans. There's still a lot of Irish down there, some of them from Ireland itself, and some of them are there illegally. INTERVIEWER: And what traditions do you try to carry on in your family? JULIA: Well, the traditions are that they know that I'm intensely interested in the Italian part of the family. I have furniture, for instance. I have, you know, [unintelligible - 00:46:38] for years and other pieces that my mother gave me when she was… HUSBAND: They have -- girls have a lot of respect for Italian culture, and one of them had been over to Italy. Take your time. JULIA: This was an -- how did you get involved with this? INTERVIEWER: I'll call you all out when it's all right because… JULIA: Are we going to meet again? INTERVIEWER: I don't think so, unless you… when I leave, feel the need to talk about something else. JULIA: Are you -- do you need -- I would like to, if possible, because I had -- now, I have four appointments this afternoon, and I would like -- I was trying to figure out how I could get copies of these tapes. INTERVIEWER: I could have that done for you at Fitchburg State College. So I'll call you… JULIA: And you have more than one? INTERVIEWER: Probably. I'll call you next week…23 JULIA: All right. INTERVIEWER: Okay? Okay. So what does it mean to be Italian to you? JULIA: It doesn't, it doesn't mean that I have been all my life aware of the great contributions that the Italians have made. But I became more aware of them as I grew older, and it made a strong attachment to family. And as I said, I still have -- my close friends are still the kids that grew up, that I grew up with, they're still the people that I grew up with, even though we all live in different places. It means certain types of food. It means, especially to me, it means this age of almost 80, I am determined foreigner, and I have -- it means that whenever I meet anybody that is Italian, that speaks Italian -- to me there's quite a big difference between the northern and southern Italian. I've always been made of… INTERVIEWER: Tell me what you just said, always been aware of… JULIA: I've always been aware of the vast differences among the people from this one peninsula that juts out into the Mediterranean, that there is such a difference in everything about them—the food and the way they speak—and it's made me very, very aware of the differences that a language can develop into, almost different languages within a cohesive place, you know. We have this boot that goes down into the ocean split down the middle by this range of mountains, and yet every section you go to, because it was at one time a collection of city states—and somebody brought that up the other day in class, it was a collection of city states—and yet my mother's experiences and the way she spoke and lived was so different from everyone else's on my street. So being an Italian, to me, meant that I had to adjust to -- when I went to school I felt very out of it, because I started school in Lexington. My father bought a house in Lexington for a few years, and I had -- I just felt a complete foreigner because I spoke hardly any English myself since we were isolated in Lexington.24 But I -- after I came back to Boston, then I had to adjust and get used to all of the different -- the girls who came from different Italian families, all of them, were. They spoke differently, their parents spoke differently; they had all these different ways of doing things. And that adjustment was a wonderful experience for me. And it means -- now, I don't think so much of modern Italy. I feel that in some ways they've grown excessively. I've heard other people made this comment, too. I've read a couple of books that said the same thing, that they've become excessively materialistic. Certainly, you know, religion -- we were not, I will say another thing, we were not a religious community. The women -- the praying that was done, the observation of religion was private. Everybody didn't lead the street and go to church on Sunday. The young kids that were making their first communion, they had to go to church. We went to church in a group, but mothers and fathers for the most part didn't go near the church. The church was run by Irish priests; nobody understood the Italians, and we hardly ever saw a priest. And so it's very different from this situation here in Fitchburg where the Italians set up their own church on top of an Irish community that moved out, you know, the Irish community and church was St. Bernard's. The Italians, back 75 years ago, decided that long ago, that they wanted their own church, and they set it up, they found an Italian priest. And we were not -- women prayed on Sunday morning, sometimes you could look up at certain windows and a woman would be sitting there with an open book which was, obviously, a [unintelligible - 00:52:54] in Italian, and she would be reading her prayers. This is [unintelligible - 00:52:59]. They observed some of the saints' days, but it was not a community that went to church. Ever. INTERVIEWER: Now, what about making first communion and confirmation? Would you go into the north end?25 JULIA: No. Some of them did. INTERVIEWER: Mm-hmm. JULIA: A couple of the families sent their daughters into the north end to make -- but most of us that were the same age, there were, you know, about two or three or four at that time, then they would go to the parish church, you know, in a group, and that was also beyond the industrial area. So it was maybe a 15-minute, 20-minute walk, and we went because the nuns, where they have were training the kids in the catechism, we went to Sunday school. Then, because they didn't want us walking to that neighborhood, as we grew older, we started going to the Jesuit church, the Immaculate Concepcion in the south end, which was an enormous church but not a parish church. But then I belonged to the choir there; some of us joined the choir. And that was an all-American experience; there was no Italians. INTERVIEWER: So Fitchburg in 1968? JULIA: I cried all the time. I didn't -- I never wanted to leave Boston. You know, I did spend a very good experience, first, the college community… INTERVIEWER: Say that again? The college community? JULIA: The college community is a wonderful place. I've always been a reader. In that respect, the kind of reading that I did was quite different from what other girls on my street did, and I am unable to explain that. I am unable to explain the direction in which my own, which you might call intellectual growth. Well, I went to an all-girls high school, and I don't know why I was attracted to classical music and literature. And I mean, I practically lived at the public library. As a matter of fact it was his branch, too. His branch of the public library, he lived on the other side of it, but you know, until my brother met him in New Guinea and he wrote to my mother, I had never a clue that he was around.26 INTERVIEWER: So when you came to Fitchburg did you make any connections with Italian people? JULIA: Not at first. Not at first, because I was still taking care of the family. Later, then, as my children grew up and they met -- because we went to St. Camillus, and that is not an ethnic church, you know. So later -- actually, in the last 10 years, I would say, I… I've met 10, 20 youths through my children. My daughter married into a Fitchburg Italian. For a little while we joined the Sons of Italy. I joined the Virginia Eleanor Lodge, and I didn't keep it up, but you know, I've met a lot… INTERVIEWER: [Unintelligible - 00:56:16] speaking, what did your parents and the parents down street, what did they want for their children? JULIA: All they wanted was for them to grow up and to go to work. The girls were not encouraged to go to school. My sister, who, as I said, who came along 13 years after I did, was first college graduate on the street. She went to, she got… INTERVIEWER: Pick it up. You said… JULIA: My sister, Mary Louise, was the first girl to go to college in our entire neighborhood. INTERVIEWER: Now, how did that happen? JULIA: She was fairly smart in school, and she was in the class of 1952 at the same high school I had gone to in a girls' high school in Boston, and she got a teacher's scholarship. And she decided she wanted to be a nurse, and how she was scared, oh, instead of going into a hospital program… INTERVIEWER: This was in… JULIA: Back… out! Instead of going in to a three-year hospital program, somebody put it into her mind to go to Boston College, a four-year degree course. Actually she went. INTERVIEWER: Wow.27 JULIA: She went out of her work at Boston City, quite a bit of it, so she could live at home and the hospital was five minutes away. She took part of her affiliation there. INTERVIEWER: Now, what did your parents think of that since they really wanted you to go to work? JULIA: Well, they felt that we should go to work. They didn't, you know -- but when Louise came along they had been sufficiently Americanized, but nobody, nobody encouraged. They expected the girls would grow up, get jobs in factories, or if they went to high school, find a job in an office and then get married. INTERVIEWER: What about the boys? JULIA: The boys, none of them went to college either, although some of them were quite smart. And one family, the boys went to college on their own. They were a little bit older than the rest. And then they -- some of them got jobs in technical areas, like different labs and in MIT, and they would stop taking courses along the job training. But almost -- one young man, which is a surprise to everyone, we knew one boy from that street that went to college; he became an officer in the Navy. No one else in his family did. There were five or six children in the family, neither girls nor boys went to college, and he was a little older than I was, and he actually went on to law school. Why? I have no idea, because his parents never spoke a word of English. And he was Sicilian, you know, and yet he went. So when I said "yet he went," it sounds like a put-down, it really isn't. It's just that none of us were encouraged to go to college, nobody. My mother couldn't understand why I was constantly reading, but it was because, you know, I worked. I mean, I helped my father in the house, peeling just because they would whitewash them. I haven't done anything like that since I got married. I refuse to do it, because that six-family house took it out of all our hides. People would move out, 28 you'd have a terrible mess, you know, you not only have the problem of trying to collect miserable rents, but every time a new family moved in, me and my father be washing and cleaning and my mother and I went after, cleaned up after all of them, and it was a -- it was really the -- it wasn't until many years afterwards, and it wasn't too long before they died, that some of the older families that had owned houses themselves sold them, and some of them came to live in my father's house. And that was a good experience. They paid their rent and very respectful, which was a surprise, because in the beginning they have a… INTERVIEWER: Is it important for the Italians to have a clean house? JULIA: Some of them. Some of them wasn't, you know. INTERVIEWER: Anything else that you'd like to add? I've been here a long time now. [Laughter] JULIA: No, I think that I -- they all -- I wanna add this: that the older that I have gotten, the more I appreciate where I grew up, dirt street and all, the more I realized the goodness and the cleverness, the ability of people from other regions of Italy, the more I appreciate the beauty of that language and what, what is world's known about the Italian culture in general. And I think that my mother and father provided me with, if nothing else, an openness about accepting people from everywhere, you know. That I got from them. Well, we're very gregarious. I appreciated all the different types of humor they had, different cooking. So then since I've left my neighborhood, I feel like I fit in everywhere. The college community? No problem. The Italian community? No problem. Where am I? I feel that I fit in, and it definitely came from this upbringing. INTERVIEWER: Okay. Could your children say the same thing? They've been brought up some way different?29 JULIA: There is one, a teacher, Maria is a schoolteacher. Kath has always done office work, she's the only one that [unintelligible - 01:02:38] go to college, but there wasn't because she couldn't -- you know, he's in the fire department, he's an electrical engineer in Boston working on the big date. [Unintelligible - 01:02:51] American, an Irish girl from Fitchburg. My son, Steven, was working for the Waste Water Treatment Plant in Burke and was attending Fitchburg State. He had gone three years to Texas -- I remember my Louis, feeling that we cooked very differently from anybody he knew, and he thought it was strange, you know, that -- I thought it was strange that other people didn't cook all this stuff then [laughter]. But my Julian, who's the youngest, is a technical writer for Lotus for Boston College. Julian went to UMass, Cathy went -- enjoyed our lives here, we've gotten used to the Georgia life here, the ones I have done. INTERVIEWER: Okay. JULIA: I learned Spanish on the job. That was the other thing that the Italian did for me. I was assigned to the Department of Public Welfare after I took that six-month refresher course. And gradually, by taking in-service examinations, I went from clerk stenographer to sort of an administrative job, and I was in the Child Support Enforcement Unit. We had a great many women coming in from Puerto Rico, all of whom spoke Spanish, and many of them brought in interpreters. Well, after I listened for a while, I suddenly realized I understood what they were saying and, if I had enough courage, I could begin to speak the Spanish language. And as a result I did. And I used to be able to conduct the interviews in Spanish. I didn't need the interpreter, you know. So that was another thing that I got out of learning Italian. Now, the proper Italian is a great surprise to me. I don't know how I started that. I'm sure I'm the only one that grew up where I grew 30 up that speaks it, and it's -- I compare it to people learning to play the piano by ear. I was so accustomed to all these different dialects that gradually the proper Italian, especially when I went to Italy, even for short periods of time, and I began to listen—and my aunt used to listen to the radio, Italian programs on the radio—and somehow the language has come. I'm fluent, but I'm not grammatical perfectly. I have to feel my way through the grammar. But I'm fluent, I can say most things that I want to say in ordinary -- and I don't know why. I feel now that I know things about myself like everyone as you grow older, that I have a gift for languages, although the grammar was difficult for me. We were only allowed to take French. In junior high school, French was the only language that was offered, and I had a bad time with the grammar. But as I've grown older, I find I can -- I've been able to master the language. I can speak, and everybody understands me. Why? I don't know. INTERVIEWER: It's a gift? JULIA: You know, even my -- when I meet the occasional person that came into the office, all the workers that came in, the Spanish-speaking workers, they all used to laugh because [laughter] there I was, I could say what I wanted to say in Spanish, and they'd all make, you know, little conversation, and I'd always talk to them. Well it isn't everyone that gets to have an audience like that. [Laughter] INTERVIEWER: [Laughter] I enjoyed it. Thank you. JULIA: I'm gonna call my friends and tell them that I will be there. I'm working…/AT/jf/jc/es
Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls. Principal Findings: In addition to earlier reported genes, we detected genome-wide significant loci on chromosomes 8 (TP53INP1, p = 1.4×10-6) and 14 (IGHV1-67 p = 7.9×10-8) which indexed novel susceptibility loci. Significance: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease ; The i-Select chips was funded by the French National Foundation on Alzheimer's disease and related disorders. The French National Fondation on Alzheimer's disease and related disorders supported several I-GAP meetings and communications. Data management involved the Centre National de Génotypage,and was supported by the Institut Pasteur de Lille, Inserm, FRC (fondation pour la recherche sur le cerveau) and Rotary. This work has been developed and supported by the LABEX (laboratory of excellence program investment for the future) DISTALZ grant (Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease) and by the LABEX GENMED grant (Medical Genomics). The French National Foundation on Alzheimer's disease and related disorders and the Alzheimer's Association (Chicago, Illinois) grant supported IGAP in-person meetings, communication and the Alzheimer's Association (Chicago, Illinois) grant provided some funds to each consortium for analyses. EADI The authors thank Dr. Anne Boland (CNG) for her technical help in preparing the DNA samples for analyses. This work was supported by the National Foundation for Alzheimer's disease and related disorders, the Institut Pasteur de Lille and the Centre National de Génotypage. The Three-City Study was performed as part of a collaboration between the Institut National de la Santé et de la Recherche Médicale (Inserm), the Victor Segalen Bordeaux II University and Sanofi-Synthélabo. The Fondation pour la Recherche Médicale funded the preparation and initiation of the study. The 3C Study was also funded by the Caisse Nationale Maladie des Travailleurs Salariés, Direction Générale de la Santé, MGEN, Institut de la Longévité, Agence Française de Sécurité Sanitaire des Produits de Santé, the Aquitaine and Bourgogne Regional Councils, Agence Nationale de la Recherche, ANR supported the COGINUT and COVADIS projects. Fondation de France and the joint French Ministry of Research/INSERM «Cohortes et collections de données biologiques» programme. Lille Génopôle received an unconditional grant from Eisai. The Three-city biological bank was developed and maintained by the laboratory for genomic analysis LAG-BRC - Institut Pasteur de Lille. Belgium sample collection: The patients were clinically and pathological characterized by the neurologists Sebastiaan Engelborghs, Rik Vandenberghe and Peter P. De Deyn, and in part genetically by Caroline Van Cauwenberghe, Karolien Bettens and Kristel Sleegers. Research at the Antwerp site is funded in part by the Belgian Science Policy Office Interuniversity Attraction Poles program, the Foundation Alzheimer Research (SAO-FRA), the Flemish Government initiated Methusalem Excellence Program, the Research Foundation Flanders (FWO) and the University of Antwerp Research Fund, Belgium. Karolien Bettens is a postdoctoral fellow of the FWO. The Antwerp site authors thank the personnel of the VIB Genetic Service Facility, the Biobank of the Institute Born-Bunge and the Departments of Neurology and Memory Clinics at the Hospital Network Antwerp and the University Hospitals Leuven. Finish sample collection: Financial support for this project was provided by the Health Research Council of the Academy of Finland, EVO grant 5772708 of Kuopio University Hospital, and the Nordic Centre of Excellence in Neurodegeneration. Italian sample collections: the Bologna site (FL) obtained funds from the Italian Ministry of research and University as well as Carimonte Foundation. The Florence site was supported by grant RF-2010-2319722, grant from the the Cassa di Risparmio di Pistoia e Pescia (Grant 2012) and the Cassa di Risparmio di Firenze (Grant 2012). The Milan site was supported by a grant from the «fondazione Monzino». The authors thank the expert contribution of Mr. Carmelo Romano. The Roma site received financial support from Italian Ministry of Health, Grant RF07-08 and RC08-09-10-11-12. The Pisa site is grateful to Dr. Annalisa LoGerfo for her technical assistance in the DNA purification studies. Spanish sample collection: the Madrid site (MB) was supported by grants of the Ministerio de Educación y Ciencia and the Ministerio de Sanidad y Consumo (Instituto de Salud Carlos III), and an institutional grant of the Fundación Ramón Areces to the CBMSO. The authors thank I. Sastre and Dr. A. Martínez-García for the preparation and control of the DNA collection, and Drs. P. Gil and P. Coria for their cooperation in the cases/controls recruitment. The authors are grateful to the Asociación de Familiares de Alzheimer de Madrid (AFAL) for continuous encouragement and help. Swedish sample collection: Financially supported in part by the Swedish Brain Power network, the Marianne and Marcus Wallenberg Foundation, the Swedish Research Council (521-2010-3134), the King Gustaf V and Queen Victoria's Foundation of Freemasons, the Regional Agreement on Medical Training and Clinical Research (ALF) between Stockholm County Council and the Karolinska Institutet, the Swedish Brain Foundation and the Swedish Alzheimer Foundation. CHARGE AGES: The AGES-Reykjavik Study is funded by National Institutes of Health (NIH) contract N01-AG-12100 (National Institute on Aging (NIA) with contributions from the National Eye Institute, National Institute on Deafness and Other Communication Disorders and National Heart, Lung, and Blood Institute (NHLBI)), the NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (the Icelandic Parliament). ASPS/PRODEM: The Austrian Stroke Prevention Study and The Prospective Dementia Register of the Austrian Alzheimer Society was supported by The Austrian Science Fond (FWF) grant number P20545-P05 (H. Schmidt) and P13180; The Austrian Alzheimer Society; The Medical University of Graz. Cardiovascular Health Study (CHS): This CHS research was supported by NHLBI contracts HHSN268201200036C, HHSN268200800007C, N01HC55222, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086, and HHSN268200960009C; and NHLBI grants HL080295, HL087652, HL105756 with additional contribution from the National Institute of Neurological Disorders and Stroke (NINDS). Additional support was provided through AG023629, AG15928, AG20098, AG027058 and AG033193 (Seshadri) from the NIA. A full list of CHS investigators and institutions can be found at http://www.chs-nhlbi.org/pi. The provision of genotyping data was supported in part by the National Center for Advancing Translational Sciences, CTSI grant UL1TR000124, and the National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DRC) grant DK063491 to the Southern California Diabetes Endocrinology Research Center. Framingham Heart Study (FHS): This work was supported by the National Heart, Lung and Blood Institute's Framingham Heart Study (Contract No. N01-HC-25195) and its contract with A_ymetrix, Inc for genotyping services (Contract No. N02-HL-6-4278). A portion of this research utilized the Linux Cluster for Genetic Analysis (LinGA-II) funded by the Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center. This study as also supported by grants from the National Institute on Aging: AG08122 and AG033193 (Seshadri). Drs. Seshadri and DeStefano were also supported by additional grants from the National Institute on Aging: (R01 AG16495; AG031287, AG033040), the National Institute of Neurological Disorders and Stroke (R01 NS17950), and the National Heart, Lung and Blood Institute (U01 HL096917, HL093029 and K24HL038444, RC2-HL102419 and UC2 HL103010. Fundació ACE would like to thank patients and controls who participated in this project. This work has been funded by the Fundación Alzheimur (Murcia), the Ministerio de Educación y Ciencia (PCT-010000-2007-18), (DEX-580000-2008-4), (Gobierno de España), Corporación Tecnológica de Andalucía (08/211) and Agencia IDEA (841318) (Consejería de Innovación, Junta de Andalucía). The authors thank to Ms. Trinitat Port-Carbó and her family for their generous support of Fundació ACE research programs. The Rotterdam Study: The Rotterdam Study was funded by Erasmus Medical Center and Erasmus University, Rotterdam; the Netherlands Organization for Health Research and Development; the Research Institute for Diseases in the Elderly; the Ministry of Education, Culture and Science; the Ministry for Health, Welfare and Sports; the European Commission;and the Municipality of Rotterdam; by grants from the Research Institute for Diseases in the Elderly (014-93-015; RIDE2), Internationale Stichting Alzheimer Onderzoek, Hersenstichting Nederland, the Netherlands Genomics Initiative–Netherlands Organization for Scientific Research (Center for Medical Systems Biology and the Netherlands Consortium for Healthy Aging), the Seventh Framework Program (FP7/2007-2013), the ENGAGE project (grant agreement HEALTH-F4-2007-201413), MRACE-grant from the Erasmus Medical Center, the Netherlands Organization for Health Research and Development (ZonMW Veni-grant no. 916.13.054). ARIC: The Atherosclerosis Risk in Communities Study (ARIC) is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute contracts N01-HC-55015, N01-HC-55016, N01-HC-55018, N01- HC-55019, N01-HC-55020, N01-HC-55021, N01-HC-55022 and grants R01-HL087641, RC2-HL102419 (Boerwinkle, CHARGE-S), UC2 HL103010, U01-HL096917 (Mosley) and R01-HL093029; NHGRI contract U01- HG004402; and NIH contract HHSN268200625226C and NIA: R01 AG033193 (Seshadri). Infrastructure was partly supported by Grant Number UL1RR025005, a component of the National Institutes of Health and NIH Roadmap for Medical Research. GERAD Cardiff University was supported by the Wellcome Trust, Medical Research Council (MRC), Alzheimer's Research United Kingdom (ARUK) and the Welsh Government. ARUK supported sample collections at the Kings College London, the South West Dementia Bank, Universities of Cambridge, Nottingham, Manchester and Belfast. The Belfast group acknowledges support from the Alzheimer's Society, Ulster Garden Villages, N. Ireland R & D Office and the Royal College of Physicians/Dunhill Medical Trust. The MRC and Mercer's Institute for Research on Ageing supported the Trinity College group. DCR is a Wellcome Trust Principal Research fellow. The South West Dementia Brain Bank acknowledges support from Bristol Research into Alzheimer's and Care of the Elderly. The Charles Wolfson Charitable Trust supported the OPTIMA group. Washington University was funded by NIH grants, Barnes Jewish Foundation and the Charles and Joanne Knight Alzheimer's Research Initiative. Patient recruitment for the MRC Prion Unit/UCL Department of Neurodegenerative Disease collection was supported by the UCLH/UCL Biomedical Centre and their work was supported by the NIHR Queen Square Dementia BRU. LASER-AD was funded by Lundbeck SA. The Bonn group would like to thank Dr. Heike Koelsch for her scientific support. The Bonn group was funded by the German Federal Ministry of Education and Research (BMBF): Competence Network Dementia (CND) grant number 01GI0102, 01GI0711, 01GI0420. The AgeCoDe study group was supported by the German Federal Ministry for Education and Research grants 01 GI 0710, 01 GI 0712, 01 GI 0713, 01 GI 0714, 01 GI 0715, 01 GI 0716, 01 GI 0717. The Homburg group was funded by the German Federal Ministry of Education and Research (BMBF): German National Genome Research Network (NGFN); Alzheimer's disease Integrated Genome Research Network; AD-IG: 01GS0465. Genotyping of the Bonn case-control sample was funded by the German centre for Neurodegenerative Diseases (DZNE), Germany. The GERAD Consortium also used samples ascertained by the NIMH AD Genetics Initiative. Harald Hampel was supported by a grant of the Katharina-Hardt-Foundation, Bad Homburg vor der Höhe, Germany. The KORA F4 studies were financed by Helmholtz Zentrum München; German Research Center for Environmental Health; BMBF; German National Genome Research Network and the Munich Center of Health Sciences. The Heinz Nixdorf Recall cohort was funded by the Heinz Nixdorf Foundation (Dr. Jur. G.Schmidt, Chairman) and BMBF. Coriell Cell Repositories is supported by NINDS and the Intramural Research Program of the National Institute on Aging. The authors acknowledge use of genotype data from the 1958 Birth Cohort collection, funded by the MRC and the Wellcome Trust which was genotyped by the Wellcome Trust Case Control Consortium and the Type-1 Diabetes Genetics Consortium, sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Allergy and Infectious Diseases, National Human Genome Research Institute, National Institute of Child Health and Human Development and Juvenile Diabetes Research Foundation International. The Nottingham Group (KM) are supported by the Big Lottery. MRC CFAS is part of the consortium and data will be included in future analyses. ADGC The National Institutes of Health, National Institute on Aging (NIH-NIA) supported this work through the following grants: ADGC, U01 AG032984, RC2 AG036528; NACC, U01 AG016976; NCRAD, U24 AG021886; NIA LOAD, U24 AG026395, R01 AG041797; MIRAGE R01 AG025259; Banner Sun Health Research Institute P30 AG019610; Boston University, P30 AG013846, U01 AG10483, R01 CA129769, R01 MH080295, R01 AG017173, R01AG33193; Columbia University, P50 AG008702, R37 AG015473; Duke University, P30 AG028377, AG05128; Emory University, AG025688; Group Health Research Institute, UO1 AG06781, UO1 HG004610; Indiana University, P30 AG10133; Johns Hopkins University, P50 AG005146, R01 AG020688; Massachusetts General Hospital, P50 AG005134; Mayo Clinic, P50 AG016574; Mount Sinai School of Medicine, P50 AG005138, P01 AG002219; New York University, P30 AG08051, MO1RR00096, and UL1 RR029893; Northwestern University, P30 AG013854; Oregon Health & Science University, P30 AG008017, R01 AG026916; Rush University, P30 AG010161, R01 AG019085, R01 AG15819, R01 AG17917, R01 AG30146; TGen, R01 NS059873; University of Alabama at Birmingham, P50 AG016582, UL1RR02777; University of Arizona, R01 AG031581; University of California, Davis, P30 AG010129; University of California, Irvine, P50 AG016573, P50, P50 AG016575, P50 AG016576, P50 AG016577; University of California, Los Angeles, P50 AG016570; University of California, San Diego, P50 AG005131; University of California, San Francisco, P50 AG023501, P01 AG019724; University of Kentucky, P30 AG028383; University of Michigan, P50 AG008671; University of Pennsylvania, P30 AG010124; University of Pittsburgh, P50 AG005133, AG030653, AG041718; University of Southern California, P50 AG005142; University of Texas Southwestern, P30 AG012300; University of Miami, R01 AG027944, AG010491, AG027944, AG021547, AG019757; University of Washington, P50 AG005136; Vanderbilt University, R01 AG019085; and Washington University, P50 AG005681, P01 AG03991. The Kathleen Price Bryan Brain Bank at Duke University Medical Center is funded by NINDS grant # NS39764, NIMH MH60451 and by Glaxo Smith Kline. Genotyping of the TGEN2 cohort was supported by Kronos Science. The TGen series was also funded by NIA grant AG034504 to AJM, The Banner Alzheimer's Foundation, The Johnnie B. Byrd Sr. Alzheimer's Institute, the Medical Research Council, and the state of Arizona and also includes samples from the following sites: Newcastle Brain Tissue Resource (funding via the Medical Research Council, local NHS trusts and Newcastle University), MRC London Brain Bank for Neurodegenerative Diseases (funding via the Medical Research Council), South West Dementia Brain Bank (funding via numerous sources including the Higher Education Funding Council for England (HEFCE), Alzheimer's Research Trust (ART), BRACE as well as North Bristol NHS Trust Research and Innovation Department and DeNDRoN), The Netherlands Brain Bank (funding via numerous sources including Stichting MS Research, Brain Net Europe, Hersenstichting Nederland Breinbrekend Werk, International Parkinson Fonds, Internationale Stiching Alzheimer Onderzoek), Institut de Neuropatologia, Servei Anatomia Patologica, Universitat de Barcelona. Marcelle Morrison-Bogorad, PhD., Tony Phelps, PhD and Walter Kukull PhD are thanked for helping to co-ordinate this collection. ADNI Funding for ADNI is through the Northern California Institute for Research and Education by grants from Abbott, AstraZeneca AB, Bayer Schering Pharma AG, Bristol-Myers Squibb, Eisai Global Clinical Development, Elan Corporation, Genentech, GE Healthcare, Glaxo-SmithKline, Innogenetics, Johnson and Johnson, Eli Lilly and Co., Medpace, Inc., Merck and Co., Inc., Novartis AG, Pfizer Inc, F. Hoffman-La Roche, Schering-Plough, Synarc, Inc., Alzheimer's Association, Alzheimer's Drug Discovery Foundation, the Dana Foundation, and by the National Institute of Biomedical Imaging and Bioengineering and NIA grants U01 AG024904, RC2 AG036535, K01 AG030514. Data collection and sharing for this project was funded by the ADNI (National Institutes of Health Grant U01 AG024904). ADNI is funded by the National Institute on Aging, the National Institute of Biomedical Imaging and Bioengineering, and through generous contributions from the following: Alzheimer's Association; Alzheimer's Drug Discovery Foundation; BioClinica, Inc.; Biogen Idec Inc.; Bristol-Myers Squibb Company; Eisai Inc.; Elan Pharmaceuticals, Inc.; Eli Lilly and Company; F. Hoffmann-La Roche Ltd and its affiliated company Genentech, Inc.; GE Healthcare; Innogenetics, N.V.; IXICO Ltd.; Janssen Alzheimer Immunotherapy Research & Development, LLC.; Johnson & Johnson Pharmaceutical Research & Development LLC.; Medpace, Inc.; Merck & Co., Inc.; Meso Scale Diagnostics, LLC.; NeuroRx Research; Novartis Pharmaceuticals Corporation; Pfizer Inc.; Piramal Imaging; Servier; Synarc Inc.; and Takeda Pharmaceutical Company. The Canadian Institutes of Health Research is providing funds to support ADNI clinical sites in Canada. Private sector contributions are facilitated by the Foundation for the National Institutes of Health (www.fnih.org). The grantee organization is the Northern California Institute for Research and Education, and the study is coordinated by the Alzheimer's Disease Cooperative Study at the University of California, San Diego. ADNI data are disseminated by the Laboratory for Neuro Imaging at the University of California, Los Angeles. This research was also supported by NIH grants P30 AG010129 and K01 AG030514. The authors thank Drs. D. Stephen Snyder and Marilyn Miller from NIA who are ex-o_cio ADGC members. Support was also from the Alzheimer's Association (LAF, IIRG-08-89720; MP-V, IIRG-05-14147) and the United States Department of Veterans Affairs Administration, Office of Research and Development, Biomedical Laboratory Research Program. Peter St George-Hyslop is supported by Wellcome Trust, Howard Hughes Medical Institute, and the Canadian Institute of Health
Republican presidential candidate Nikki Haley regaled a pro-Israel lobby group Wednesday with stories of Chinese mind-control attacks, among other foreign bugaboos. Addressing the group at a posh country club in Tenafly, New Jersey, the former South Carolina governor and UN ambassador delivered prospective donors a combination of big-tent domestic politics and a heavy dose of hawkish foreign policy, especially in the Middle East.Some of her talking points harkened back to Bush administration. Haley warned that "we can never be so arrogant to think that another 9/11 won't happen," and mocked UN inspectors' claims that they were able to investigate the Iranian nuclear program, just as the Bush administration had mocked UN inspectors' inability to find Iraqi weapons of mass destruction.In a modern twist on War on Terror fears, Haley frightened her audience with the claim that China was developing "neurostrike" weapons, possibly to use on Americans.The campaign remarks to the low-profile event hosted by the pro-Israel lobby group NORPAC, were clearly aimed at wooing potential donors more than making headlines. The event served as a window into the type of constituency Haley considers her core supporters — literal country-club Republicans with a hawkish foreign policy outlook and neoconservatives — and how she plans to appeal to them.Tenafly is a leafy, picturesque upper-middle-class suburb. Just outside New York City, the town boasts a median household income of $153,000 per year and an average home value around $1 million. Downtown Tenafly looks straight out of a Norman Rockwell painting, with a classic 1950s diner, a colonial-style church, a Lubavitcher synagogue, and an ornate brick train station that has been turned into a trendy cafe.Organizers chose a venue that was a little more exclusive: the Knickerbocker, one of Tenafly's two country clubs. The event was not advertised on Haley's campaign website or official social media, only through print ads in a few local newspapers and on the NORPAC blog.The Knickerbocker main hall, which had around 300 seats plus standing room, filled up before Haley arrived. A man wearing a yarmulke on his head and holding a red "Trump was right" trucker hat in his hand wandered the aisle, looking for open seats, while 80s rock music blared from the loudspeakers.
The Knickerbocker country club, Tenafly, NJ. Photo: Matthew PettiTickets to Haley's speech were free, but there had also been a VIP fundraising reception before the main event, hosted by Wall Street investment banker Bennett Schachter. NORPAC had advertised a Haley fundraising dinner open to donors who committed $6,600 or more, reports Al-Jazeera journalist Ali Harb.On stage, Schachter thanked "our friends" at the American Israel Public Affairs Committee for their "support behind the scenes" for the event."If the local people are getting behind Nikki and supporting her and there's this big swell of momentum, that sends a message to the broader Republican Party, which says this candidate actually is reaching people on the ground level, she's not aloof, she's not unattainable, she's not unrelatable," Schachter had explained on the radio show "JM in the AM" a few days before the event. "That sends a message to the larger funders, and when you get that kind of swell, that leads to lots of money."Haley experienced a boost in polls after the first Republican debate in August. And a recent CNN poll found that she was the Republican with the strongest lead over incumbent president Joe Biden in the general election.However, she still lags far behind her Republican rivals. Haley's FiveThirtyEight polling average is 6.3 percent in the primaries, fourth place among Republican candidates, after biotech financier Vivek Ramaswamy. Former president Donald Trump remains the frontrunner.During his radio interview, Schachter praised Haley for going "full throttle" in support of Israel at the Republican debate, when she bashed Ramaswamy's plan to wean Israel off of U.S. military aid. He predicted that Haley "will carry the Right politically, she will carry the Center politically, and she will carry a lot of the Left."Fellow event organizer Joey Folkman added that he knew Haley from the time his family owned a factory in South Carolina. He praised the former governor for being the first to remove the Confederate flag from the state capitol and the first to ban boycotts of Israel.Haley and the organizers pitched the same combination of moderate domestic politics and hawkish foreign policy on stage."We are dying to have a Republican in the White House, yet not enough are rallying around Ambassador Haley, who — unlike the current frontrunner [Trump] — has never lost an election, and has certainly never lost to Joe Biden," Folkman said in his introduction. "We are going to stop being enticed by campaigns that prey on divisiveness, anger, immaturity, conspiracy, and retribution."Haley herself said that, when she faced bullying in school, her mother told her that "it isn't your job to show them how you're different, it's to show you how you're similar."She cited that same childhood trauma as a reason for her pro-Israel stance. The Israeli ambassador to the United Nations was "humiliated" by the UN Security Council, said Haley, when the Obama administration refused to veto a Security Council resolution condemning Israeli settlements in the occupied Palestinian territories."The kid on the playground that got bullied got her back up," Haley said. "I never wanted anyone to feel like that."Haley complained that President Joe Biden only met Israeli prime minister Benjamin Netanyahu several months into Netanyahu's term, and only "on the sidelines of the United Nations, not at the White House." (The meeting took place the same day as the campaign event.) She said that Americans needed "moral clarity about who your friends are."Echoing one of her lines from the Republican debate, Haley declared that "Israel doesn't need America. America needs Israel." She argued that the same was true for the United Arab Emirates: "It was never that Israel needed them, they needed Israel."If Israel was the unsung hero of Haley's worldview, Iran was the villain. Haley made her usual points about the threat posed by Russia and China, and the need to support Ukraine and Taiwan, but reserved her most vehement, emotional condemnation for Iran.Iran had agreed last month to send home five Americans held in Iranian prisons, in exchange for five Iranians held in American prisons, as well as $6 billion in Iranian money frozen in a South Korean bank to be used only for humanitarian purposes. Biden administration officials greeted the American captives at the airport on Monday. Haley claimed that the prisoner exchange "put a bounty on every American's head." And she complained that Iranian president Ebraham Raisi, a "murderous thug," thanked America for the deal with an anti-American speech at the United Nations."You can't change a culture," Haley said, although she was careful to clarify that she meant the culture of "this regime, not the Iranian people."Haley added that any future deal with Iran "needs to include Israel and the Arab countries."She accused Biden of putting Saudi crown prince Mohammad bin Salman in a position that "would make [bin Salman] look weak" if Saudi Arabia accepted any U.S. proposal. Because of that, Haley argued, Saudi Arabia was now unwilling to sign the U.S.-Israeli-Saudi deal that Biden is pushing for.The focus on the Middle East didn't mean China was off the hook. Haley claimed that the Chinese government "has been preparing for war with us for years."To audible gasps from the audience, she called China the "lead developer of 'neurostrike' weapons, engineered to change the brain activity of military commanders or segments of the population." Haley had issued the same warning in a July interview with CNBC, and again at an August speech in Iowa.The term "neurostrike" was popularized by a thinly-evidenced July 2023 article, which speculated that China is developing strategies to "directly attack, or even control, mammalian brains." The researchers, calling themselves the CCP BioThreats Initiative, have previously made alarmist claims about Chinese virus research, nanotechnology, and electromagnetic pulse weapons. She also contended that China, Russia, Iran, and North Korea were spreading "disinformation" to turn Americans against each other. "The one thing that bothers me the most is the national self-loathing that's taken over our country," Haley said. "All of our enemies are circling us in a way that is really dangerous."
Dottorato di ricerca in Memoria e materia dell'opera d'arte attraverso i processi di produzione , storicizzazione, conservazione, musealizzazione ; Il progetto I codici e la cultura scientifica alla corte dei Papi tra fine XIII e primi decenni del XV secolo, con particolare attenzione ai manoscritti miniati della Biblioteca Papale di Avignone si articola in tre snodi principali, corrispondenti alle partizioni essenziali in cui è stato suddiviso il lavoro. Innanzitutto si è tratteggiata una panoramica della storia, delle caratteristiche e degli sviluppi degli inventari delle librariae pontificie tra 1295 e 1594, fonti e testimonianze essenziali da cui partire, per indagare la vastità degli interessi culturali, in particolare scientifici, della corte papale. Tale esame, oltre a permettere di delineare l'effettiva presenza e consistenza di codici scientifici alla corte dei pontefici tra XIII e XV secolo e di rintracciare e riconoscere un nucleo significativo di manoscritti, oggi conservati in diversi fondi di biblioteche europee (Biblioteca Apostolica Vaticana, Biblioteca Alessandrina, Bibliothèque Nationale de France, British Library, Biblioteca capitular di Toledo), a seguito della parziale dispersione e frammentazione della biblioteca papale, ha permesso di sottolineare, seguendo la prospettiva di lunga durata, le palesi divergenze esistenti in tale campo del sapere con il canone quattrocentesco redatto da Tommaso Parentucelli per la costituzione di una teorica biblioteca umanistica. Per sostanziare tale confronto si è fatto riferimento alla presenza degli item di natura scientifica elencati nei diversi inventari, inseriti in appendice. Quindi si è proposta una disamina della fortuna del pensiero scientifico all'interno della corte pontificia tra seconda metà del XIII e XIV secolo, prendendo in esame lo Studium di Viterbo, maggiore centro culturale del tempo in tale campo, e il pontificato di Bonifacio VIII (1297-1304), per giungere ai due casi peculiari, durante il papato avignonese, di Giovanni XXII (1316-1334) e Clemente VI (1342-1352), scelti non solo per la personale tensione verso le scienze esatte, ma anche per i riflessi risultanti nella loro azione politica: significativa in tal senso la bolla Super illius specula, promulgata nel 1326 da Giovanni XXII, e altrettanto rilevante l'intenso dibattito inerente la Visione beatifica sviluppatosi sotto il medesimo pontefice oppure alla questione sulla determinazione della data della Pasqua. Infine si è affrontato il nucleo dei codici scientifici miniati della biblioteca papale di Avignone. Da tale lavoro, basato principalmente sull'istituzione, ove possibile, di confronti con la coeva produzione liturgico-giuridica propria della curia pontificia, sulla quale fino a oggi si sono concentrati gli studi inerenti la miniatura avignonese, è emerso che tale gruppo di manoscritti è costituito in prevalenza da codici di studio, appartenuti probabilmente a membri della curia, entrati solo successivamente a far parte della collezione libraria papale, in virtù dello ius spolii, come recentemente dimostrato per il Borgh. 353 (Città del Vaticano, Biblioteca Apostolica Vaticana). Solo alcuni manoscritti potrebbero ritenersi il frutto di una specifica commissione pontificia, come evidente dalle dediche presenti sia nel ms 81 della Biblioteca Alessandrina di Roma, contenente il Commento alla Physioniomia di Guglielmo di Myrica, sia nel ms lat. 7293 della Bibliothèque Nationale de France, copia acefala del De instrumento rivelatore di Levì Ben Gerson. Il carattere privato di tali manoscritti appare ancor più evidente qualora si passi all'analisi degli apparati decorativi, dove si constata in alcuni casi la totale o parziale assenza di pagine d'incipit riccamente miniate, di iniziali rubricate o filigranate quand'anche previste dall'ordinator. Accanto a considerazioni prettamente stilistiche si sono anche condotte riflessioni inerenti l'iconografia delle iniziali istoriate dal momento che spesso risultano essere caratterizzate da raffigurazioni del tutto estranee alla materia trattata all'interno delle opere di cui qualificano l'incipit. La presenza di soggetti quali ad esempio la Vergine in maestà, del Cristo in trono o della Sacra famiglia consueti in testi di contenuto religioso, si è legata alla volontà di rendere più appetibile a un pubblico non laico la materia profana trattata. Accanto a tale tesi, probabilmente risultato dell'esclusiva volontà del committente, non si può non proporre anche una lectio facilior di tale discrepanza tra testo ed immagine, che potrebbe forse trovare la sua ragion d'essere forse nel fatto che gli artisti, abituati a realizzare per la curia testi di carattere sacro, abbiano usato i medesimi modelli a loro disposizione anche nella decorazione di codici di natura del tutto profana, ricorrendo ad un repertorio di soggetti standardizzato, senza preoccuparsi di aggiornarlo a esigenze diverse e in particolare a quelle legate ai contenuti di opere quali la Physica o la Methapysica. Tale parte del lavoro è stata arricchita e supportata da schede catalografiche, composte da un'attenta analisi e descrizione codicologica, alla quale fa seguito una sezione storico-critica incentrata sulle vicende sia compositive sia collezionistiche di detti codici e sul loro attuale stato conservativo. ; The project Codes and Scientific Culture at the Court of the Popes in Late Thirteenth Century and in the Early Decades of the Fifteenth Century, with Particular Attention to the Illuminated Manuscripts of the Papal Library of Avignon is divided into three main parts, corresponding to the essential partitions in which is partitioned the researching work. The first one is dedicated to an overview of the history, the characteristics and the developments of papal libraries inventories between 1295 and 1594. Its matter of fact that these ones are essential sources and testimonies for investigate the cultural interests, particularly the scientific one in the papal court. This examination, as well as allowing you to outline the actual presence and consistency of scientific codes in the court of the popes between the thirteenth and fifteenth century, tracking and recognizing a significant core of manuscripts, now preserved in various collections of European libraries (Biblioteca Apostolica Vaticana, Bibliotheca Alexandrina, Bibliothèque Nationale de France, British Library, Toledo Capitular Library), following the partial dispersion and fragmentation of the papal library, allowed to point out, following the long-term perspective, the obvious differences that exist in this field of knowledge with the canon century written by Thomas Parentucelli for the establishment of a theoretical humanistic library. This point has been substantiated by comparison of the items listed in the various scientific inventories, included in the book's appendix. The second part of the volume concerned an examination of the fortune of scientific thought in the papal court in the second half of the thirteenth and fourteenth centuries, examining the Studium of Viterbo: the greater the cultural center of the time in this field; the pontificate of Boniface VIII (1297 -1304); and finally outlining two peculiar cases, during the Avignon papacy of John XXII (1316-1334) and Clement VI (1342-1352), chosen not only for the personal tension towards the exact sciences, but also for the reflections resulting in their political action: significant in this sense, the Super illius note, promulgated in 1326 by Pope John XXII, the intense debate regarding the Beatific Vision developed under the same pope or the question of determining the date of Easter. In the last section, we addressed the core of the scientific codes illuminated the papal library in Avignon. This work has based mainly on the establishment, where possible, comparisons with contemporary liturgical and legal production linked to the papal curia, on which up now it has focused studies. It was found that this group of manuscripts is mainly consisting of study codes, probably belonged to members of the Curia, which came only later to be part of the papal library collection, by virtue of jus spolii, as recently demonstrated, for example in the case of Borgh. 353 (Vatican City, Biblioteca Apostolica Vaticana). Only few manuscripts may be considered the result of a specific pontifical commission, as evident from the dedications both the ms 81 of the Alessandrina Library of Rome, containing a commentary on the Physioniomia of William of Myrica, or the ms lat. 7293 of the Bibliothèque Nationale de France, a Levi ben Gerson headless copy of the De instrumento rivelatore. The private nature of the manuscripts is even more evident when you analyze the decorative device. It is found in some cases the total or partial absence of pages of richly illuminated incipit, in other ones the absence of rubricated or pen worked initials even provided by ordinator. In addition to stylistic considerations it has also conducted reflections about historiated initials. They often turn out to be characterized by depictions completely unrelated to the topic within the works which qualify the opening words. The presence of subjects such as the Virgin in majesty, the enthroned Christ or the Holy Family usually present in texts of religious content, it is linked to the desire to make it more agreeable to a secular audience the profane matter treated in the books, so probably the exclusive will result of the client. However we can also propose a lectio facilior of this discrepancy between text and image. It could possible find its reason in the fact that artists, accustomed to achieve sacred texts for curia, they used the same models in the decoration of codes of secular nature, using a standardized repertoire of subjects, not bothering to upgrade it to the different needs of 3 operas like Physica and Metaphysica. This last section has been enriched and supported by catalog entries, consisting of careful analysis and description codex, which is followed by a historical-critical section focused on the compositional
Captura de Radovan KaradzicEl ex presidente de la República Serbia de Bosnia, Radovan Karadzic, de 63 años, es acusado de genocidio y crímenes de guerra . Es uno de los hombres más buscados del mundo, ha sido detenido el pasado martes en Serbia.Apodado el "carnicero de Sarajevo", estuvo prófugo desde 1996, está inculpado por el Tribunal Penal Internacional para la antigua Yugoslavia (creado ad hoc para juzgar los delitos cometidos durante ese conflicto).Se le acusa también de haber orquestado las ejecuciones de hasta 8.000 musulmanes en Srebrenica durante la guerra en Bosnia en 1995.Se ocultaba tras una identidad falsa y un aspecto irreconocible, con barba, pelo largo y mucho más delgado. Ejercía la medicina alternativa en Belgrado, donde ha sido detenido. Varios medios informan al respecto:"CNN":"Fugitive Karadzic hid as bearded medic":http://edition.cnn.com/2008/WORLD/europe/07/22/serb.arrest/index.html"Time":"Karadzic's Arrest Comes Too Late":http://www.time.com/time/world/article/0,8599,1825366,00.html"Karadzic Hid with False Identity":http://www.time.com/time/world/article/0,8599,1825377,00.html"Judge Orders Karadzic to UN Tribunal":http://www.time.com/time/world/article/0,8599,1825268,00.html"Le Monde":"Karadzic se cachait à Belgrade sous une fausse identité":http://www.lemonde.fr/europe/article/2008/07/22/le-serbe-radovan-karadzic-inculpe-de-genocide-a-ete-arrete_1075780_3214.html#ens_id=1075781"La Serbie solde en partie les comptes de son passé":http://www.lemonde.fr/europe/article/2008/07/22/la-serbie-solde-en-partie-les-comptes-de-son-passe_1075844_3214.html#ens_id=1075781"Radovan Karadzic, fourrier d'un sanglant ultranationalisme serbe":http://www.lemonde.fr/europe/article/2008/07/22/radovan-karadzic-l-icone-de-l-ultranationalisme-serbe_1075820_3214.html"New York Times":"Serb Officials Detail Capture of Karadzic":http://www.nytimes.com/2008/07/23/world/europe/23serbia.html?_r=1&ref=world&oref=slogin"La Nación": "Satisfacción en la UE por la detención de Radovan Karadzic: Sin embargo, los líderes mostraron prudencia sobre los avances con Serbia a partir del arresto del criminal de guerra más buscado; no declaró en su primer interrogatorio":http://www.lanacion.com.ar/nota.asp?nota_id=1032472"Detienen al criminal de guerra más buscado: Es Radovan Karadzic, acusado de genocidio en los Balcanes":http://www.lanacion.com.ar/nota.asp?nota_id=1032386"The Economist":"Arrest of a strongman: Radovan Karadzic is arrested at last, in a big boost to Serbia's prospects of joining the European Union":http://www.economist.com/world/europe/displayStory.cfm?story_id=11778164&source=features_box_main"Los Angeles Times":"Bosnian Serb war crimes suspect Radovan Karadzic caught":http://www.latimes.com/news/nationworld/world/la-fg-warcrime22-2008jul22,0,7520714.story"Times":"Wanted fugitive Radovan Karadzic developed alter ego as New Age doctor":http://www.timesonline.co.uk/tol/news/world/europe/article4377240.ece"The dark life and times of Radovan Karadzic":http://www.timesonline.co.uk/tol/news/world/europe/article4377484.ece"Eyewitness: the role of Karadzic in Sarajevo's vicious civil war: As a foreign correspondent for The Times, Edward Gorman visited many theatres of war during the 1990s. Here he recalls the dark days of the siege of Sarajevo":http://www.timesonline.co.uk/tol/news/world/europe/article4377963.ece"Factfile: Bosnia's bloody history:The tangled and troubled history to the Bosnian civil war, which saw the worst massacres in Europe since WW2":http://www.timesonline.co.uk/tol/news/world/europe/article4378742.ece"El Tiempo":"Arrestado el ex jefe militar serbobosnio Radovan Karadzic, acusado de genocidio":http://www.eltiempo.com/mundo/europa/home/arrestado-el-ex-jefe-militar-serbobosnio-radovan-karadzic-acusado-de-genocidio-_4388156-1"El Universal": "Envían a La Haya a Karadzic: El fiscal Vladimir Vukcevic dijo el martes a la prensa que el juez emitió la orden para la entrega del sospechoso a la corte internacional por 11 crímenes de guerra":http://www.eluniversal.com.mx/notas/524272.html"MSNBC":"War crimes suspect quizzed after decade on run: Bosnian Serb leader Karadzic worked as doctor while hunted for massacres":http://www.msnbc.msn.com/id/25793223/"Background, quotes on The Hague, Karadzic: Tribunal facts and what key figures have to say about the fugitive's arrest":http://www.msnbc.msn.com/id/25798405/"El Mercurio":"Presunto criminal de guerra requerido en La Haya: Luego de 12 años de búsqueda detienen a Radovan Karadzic, el "carnicero de Sarajevo"":http://diario.elmercurio.com/2008/07/22/internacional/_portada/noticias/B62A3BF4-561F-42DF-B372-E6A97619E49E.htm?id={B62A3BF4-561F-42DF-B372-E6A97619E49E}"El País" de Madrid:"Celebración en Sarajevo, disturbios en Belgrado: Cientos de nacionalistas serbios se enfrentan con la Policía por la detención de Radovan Karadzic, muy celebrada en Bosnia":http://www.elpais.com/articulo/internacional/Celebracion/Sarajevo/disturbios/Belgrado/elpepuint/20080722elpepuint_13/Tes"Detenido en Serbia Karadzic, el criminal de guerra más buscado":http://www.elpais.com/articulo/internacional/Detenido/Serbia/Karadzic/criminal/guerra/buscado/elpepuint/20080722elpepuint_2/Tes"Los ministros de Exteriores de la UE esperarán al informe del TPYI para descongelar el pacto de adhesión de Serbia: La detención de Karadzic acerca al país de los Balcanes a Europa":http://www.elpais.com/articulo/internacional/ministros/Exteriores/UE/esperaran/informe/TPYI/descongelar/pacto/adhesion/Serbia/elpepuint/20080722elpepuint_9/Tes AMERICA LATINA"MSNBC" publica: "Haiti food aid lags, hunger deepens: As nation starves, aid is stuck in port or inside warehouses":http://www.msnbc.msn.com/id/25773473/"El País" de Madrid informa: "Mueren cuatro militares venezolanos y un boliviano al caer un helicóptero en el centro de Bolivia: La aeronave iba a ser utilizada hoy por el presidente Evo Morales":http://www.elpais.com/articulo/internacional/Mueren/militares/venezolanos/boliviano/caer/helicoptero/centro/Bolivia/elpepuint/20080721elpepuint_13/Tes"MSNBC" publica: "Helicopter crashes in Bolivia, killing five: Copter was often used to transport Bolivian president":http://www.msnbc.msn.com/id/25785714/"CNN" informa: "Dolly intensifies; Texas and Mexico brace for hurricane":http://edition.cnn.com/2008/US/weather/07/21/tropical.weather/index.html"La Ancion" publica: "La crisis política / La embestida kirchnerista contra el vicepresidente: El Gobierno echó a seis funcionarios de Cobos":http://www.lanacion.com.ar/nota.asp?nota_id=1032410"El Mercurio" publica: "El secretario de Agricultura sería la primera baja del gabinete argentino":http://diario.elmercurio.com/2008/07/22/internacional/internacional/noticias/217A4F30-1D6C-4B42-9354-B2E194388F5A.htm?id={217A4F30-1D6C-4B42-9354-B2E194388F5A}"CNN" publica: "Chavez set to spend big on Russian weapons":http://edition.cnn.com/2008/WORLD/americas/07/22/chavez.russia/index.html"La Nación" informa: "Chávez inició una estratégica visita a Rusia: El mandatario realizó una nueva compra de armas y selló importantes acuerdos energéticos tras reunirse con su par ruso, Dimitri Medvedev":http://www.lanacion.com.ar/nota.asp?nota_id=1032471"The Economist" analiza: "Deadly masaje: How not to tackle a soaring murder rate":http://www.economist.com/world/la/displaystory.cfm?story_id=11750858"El Mercurio" informa: "20 muertos habría dejado ataque a base de las FARC": http://diario.elmercurio.com/2008/07/22/internacional/internacional/noticias/E029D5C3-F87C-466E-81E2-32434314CDC9.htm?id={E029D5C3-F87C-466E-81E2-32434314CDC9}"The Economist" analiza: "Mending an icon: How Rio's first good governor in decades is starting to renew Brazil's most famous city": http://www.economist.com/world/la/displaystory.cfm?story_id=11750451 ESTADOS UNIDOS / CANADA "New York Times" publica: "Obama Meets Iraqi Officials in Baghdad":http://www.nytimes.com/2008/07/22/us/politics/22obama.html?_r=1&ref=world&oref=slogin"CNN" informa: "Obama finds 'consensus' in Iraq for U.S. troop withdrawal":http://edition.cnn.com/2008/WORLD/meast/07/22/obama.mideast/index.html"El Mercurio" de Chile publica: "Campaña electoral por la Casa Blanca: Gira de Obama desata frenesí periodístico en Estados Unidos":http://diario.elmercurio.com/2008/07/22/internacional/internacional/noticias/F0B3A5F6-8B0C-4F9B-B389-83E111BEDDB1.htm?id={F0B3A5F6-8B0C-4F9B-B389-83E111BEDDB1}"The Economist" analiza: "The Hispanic vote: ¡Voten por mi!. Latino voters are turning away from John McCain. That's a symptom of a bigger problem for Republicans":http://www.economist.com/world/na/displaystory.cfm?story_id=11750600"Time" informa: "Never Underestimate McCain, But.":http://www.time.com/time/politics/article/0,8599,1825337,00.html"Time" publica sitio web sobre elecciones en los Estados Unidos: "The Page":http://thepage.time.com/"La Nación" informa: "Guantánamo: comenzó el primer juicio: El acusado es el ex chofer de Osama ben Laden, que ayer se declaró inocente ante un tribunal militar":http://www.lanacion.com.ar/nota.asp?nota_id=1032343"Time" publica: "Bin Laden Driver Pleads Not Guilty":http://www.time.com/time/world/article/0,8599,1825089,00.html"El País" de Madrid informa: "El chófer de Bin Laden niega las acusaciones en el primer juicio en Guantánamo: Salim Ahmed Hamdan se enfrenta a una pena de cadena perpetua por conspiración y apoyo a actividades terroristas": http://www.elpais.com/articulo/internacional/chofer/Bin/Laden/niega/acusaciones/primer/juicio/Guantanamo/elpepuint/20080721elpepuint_6/Tes EUROPA "The Economist" analiza: "Bosnia's future: Balkan end-games. The long and winding road towards the European Union":http://www.economist.com/world/europe/displaystory.cfm?story_id=11751332"El País" de Madrid publica: " Sarkozy transmite a Irlanda su respeto al resultado del referéndum: El mandatario francés, que ejerce la presidencia rotatoria de la UE, se ha reunido con el primer ministro de Irlanda Brian Cowen en busca de una explicación al 'no'": http://www.elpais.com/articulo/internacional/Sarkozy/transmite/Irlanda/respeto/resultado/referendum/elpepuint/20080721elpepuint_16/Tes"El Mercurio"de Chile informa: "Sarkozy logra estrecha victoria con aprobación a reforma constitucional":http://diario.elmercurio.com/2008/07/22/internacional/_portada/noticias/11AF2738-5487-43B6-9D0F-71C578D6BE24.htm?id={11AF2738-5487-43B6-9D0F-71C578D6BE24}"MSNBC" publica: "Spanish police smash 'most wanted' ETA cell: 9 held as raids target Basque separatist group following series of attacks":http://www.msnbc.msn.com/id/25799230/"CNN" indorma: "Nine ETA bombing suspects arrested":http://edition.cnn.com/2008/WORLD/europe/07/22/spain.arrests/index.html"La Nación" informa: "La lucha contra el terrorismo en España: Desarticulan el comando más activo de ETA. Detuvieron a nueve personas, entre ellos el jefe; serían los responsables de la mayoría de los atentados cometidos tras el fin de la tregua":http://www.lanacion.com.ar/nota.asp?nota_id=1032470"El País" de Madrid informa: "España confirma que el Rey sí verá a Chávez: Un comunicado del Gobierno español dice que se reunirán el viernes en Mallorca, a pesar de que el presidente venezolano desmintió ayer que haya confirmado el encuentro": http://www.elpais.com/articulo/internacional/Espana/confirma/Rey/vera/Chavez/elpepuint/20080721elpepuint_2/Tes"La Nación" publica: "Cerraron el caso Maddie por falta de evidencias: Los padres harán otra investigación":http://www.lanacion.com.ar/nota.asp?nota_id=1032387"The Economist" analiza: "Berlusconi fiddles, Italy burns: Silvio Berlusconi's government is turning out to be depressingly similar to his previous one":http://www.economist.com/world/europe/displaystory.cfm?story_id=11751325Asia – Pacífico /Medio OrieNTE"MSNBC" informa: "Myanmar cyclone caused $4 billion in damage: Country needs at least $1 billion in aid over three years, U.N. says":http://www.msnbc.msn.com/id/25785731/"The Economist" informa: "Business in China: Busting trust. The land of the mega-monopoly is about to adopt an antitrust law":http://www.economist.com/business/displaystory.cfm?story_id=11751042"Time" publica: "China Pulls Troops From Quake Zone":http://www.time.com/time/world/article/0,8599,1825310,00.html"MSNBC" analiza: "Olympic city halves traffic to aid polluted skies: Car ban forces Beijing residents to take public transport in clean air bid":http://www.msnbc.msn.com/id/25778988/"CNN" infroma: "Indian government's future on a knife edge":http://edition.cnn.com/2008/WORLD/asiapcf/07/22/india.vote/index.html"Time" publica: "India MPs to Hold Confidence Vote":http://www.time.com/time/world/article/0,8599,1825382,00.html"El País" de Madrid informa: "El tifón Kalmaegi causa 18 muertos en Taiwán: El tifón ha causado graves inundaciones, corrimientos de tierra y pérdidas agrícolas de alrededor de diez millones de euros":http://www.elpais.com/articulo/internacional/tifon/Kalmaegi/causa/muertos/Taiwan/elpepuint/20080721elpepuint_1/Tes"Time" informa: "ASEAN Turns Blind Eye to Burma Rights":http://www.time.com/time/world/article/0,8599,1825357,00.html"El País" de Madrid informa: "Brown: "La paz entre palestinos e israelíes está al alcance de la mano": El líder laborista, primer 'premier' británico que habla ante la 'Knesset' (parlamento israelí).- Exige de nuevo a Irán que suspenda su programa nuclear":http://www.elpais.com/articulo/internacional/Brown/paz/palestinos/israelies/alcance/mano/elppgl/20080721elpepuint_11/Tes"La Nación": "Brown pidió a Irán que cese su plan nuclear":http://www.lanacion.com.ar/nota.asp?nota_id=1032345"Times" publica: "Bulldozer driver shot dead in Jerusalem after ramming cars":http://www.timesonline.co.uk/tol/news/world/article4378076.ece AFRICA"El País" de Madrid publica: "Gobierno y oposición de Zimbabue acuerdan iniciar un proceso de diálogo para salir de la crisis: El líder del MDC, vencedor de las elecciones que nunca reconoció el régimen de Mugabe, firmará en persona el acuerdo":http://www.elpais.com/articulo/internacional/Gobierno/oposicion/Zimbabue/acuerdan/iniciar/proceso/dialogo/salir/crisis/elpepuint/20080721elpepuint_12/Tes"CNN" informa: "Zimbabwe rivals sign deal on talks":http://edition.cnn.com/2008/WORLD/africa/07/21/zimbabwe.deal/index.html"Time" informa: "Breakthrough in Zimbabwe: Let's Talk":http://www.time.com/time/world/article/0,8599,1825151,00.html"CNN" publica: "Zimbabwe: Inflation 'highest in the world'":http://edition.cnn.com/2008/WORLD/africa/07/17/zimbabwe.inflation.ap/index.html"The Economist" analiza: "Sudan's leader is accused, but others can expect to follow: Will the indictment of Sudan's president for alleged war crimes help or hinder the prospects for peace in Darfur?":http://www.economist.com/world/africa/displaystory.cfm?story_id=11751353ECONOMIA"CNN" informa: "Oil jumps $2 on Iran, storm: Crude prices bounce back from $16 slide as Iran nuclear talks end without agreement and traders fear tropical storm in Gulf of Mexico.":http://money.cnn.com/2008/07/21/markets/oil/index.htm?postversion=2008072115"The Economist" publica su informe semanal: "Business this week":http://www.economist.com/displaystory.cfm?story_id=11751734&CFID=13935362&CFTOKEN=69812019"El País" de Madrid publica: "El rescate de Fannie Mae y Freddie Mac le costará al contribuyente 25.000 millones de dólares: Según la Oficina de Presupuesto del Congreso.- Los dos bancos hipotecarios siguen su desplome en la bolsa":http://www.elpais.com/articulo/economia/rescate/Fannie/Mae/Freddie/Mac/le/costara/contribuyente/25000/millones/dolares/elpepueco/20080722elpepueco_8/TesOTRAS NOTICIAS"El País" de Madrid publica: "Movilización mundial contra las FARC: Ingrid Betancourt pide en París la liberación de todos los secuestrados. Miles de asistentes a un concierto reclaman el fin de la guerrilla en Colombia":http://www.elpais.com/articulo/internacional/Ingrid/Betancourt/pide/Paris/liberacion/todos/secuestrados/elpepuint/20080721elpepiint_3/Tes"CNN" informa: "World rallies for FARC hostages' freedom":http://edition.cnn.com/2008/WORLD/americas/07/20/colombia.hostages.ap/index.html"The Economist" publica: "Iran and America: A surprising move. Why America is sending a top man to talk directly to the Iranians":http://www.economist.com/world/africa/displaystory.cfm?story_id=11751318
How to Cite This Article: Ahmadi Doulabi M, Sajedi F, Vameghi R, Mazaheri MA, Akbarzadeh Baghban AR. Socioeconomic Status Index to Interpret Inequalities in Child Development. Iran J Child Neurol. Spring 2017; 11(2):13-25.AbstractObjectiveThere have been contradictory findings on the relationship between Socioeconomic Status (SES) and child development although SES is associated with child development outcomes. The present study intended to define the relationship between SES and child development in Tehran kindergartens, Iran.Materials & Methods This cross-sectional survey studied 1036 children aged 36-60 month, in different kindergartens in Tehran City, Iran, in 2014-2015.The principal factor analysis (PFA) model was employed to construct SES indices. The constructed SES variable was employed as an independent variable in logistic regression model to evaluate its role in developmental delay as a dependent variable.Results The relationship between SES and developmental delay was significant at P=0.003. SES proved to have a significant (P<0.05) impact on developmental delay, both as an independent variable and after controlling risk factors.Conclusion There should be more emphasis on developmental monitoring and appropriate intervention programs for children to give them higher chance of having a more productive life. 1. Haghdoost AA. Complexity of the Socioeconomic Status and its Disparity as a Determinant of Health. Int J Prev 2012; 3(2):75. 2. Behavioral and social sciences research. Measuring Socioeconomic Status. e-Source 2013; Available from:http://www.esourceresearch.org 3. Bradley RH, Corwyn RF. Socioeconomic status and child development. 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Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumference and waist-hip ratio from up to 200,452 adults of European (n = 180,423) or other ancestry (n = 20,029). We standardized PA by categorizing it into a dichotomous variable where, on average, 23% of participants were categorized as inactive and 77% as physically active. While we replicate the interaction with PA for the strongest known obesity-risk locus in the FTO gene, of which the effect is attenuated by ~30% in physically active individuals compared to inactive individuals, we do not identify additional loci that are sensitive to PA. In additional genome-wide meta-analyses adjusting for PA and interaction with PA, we identify 11 novel adiposity loci, suggesting that accounting for PA or other environmental factors that contribute to variation in adiposity may facilitate gene discovery. ; The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute; the National Institutes of Health; or the U.S. Department of Health and Human Services. Funding for this study was provided by the Aase and Ejner Danielsens Foundation; Academy of Finland (102318; 104781, 120315, 123885, 129619, 286284, 134309, 126925, 121584, 124282, 129378, 117787, 250207, 258753, 41071, 77299, 124243, 1114194, 24300796); Accare Center for Child and Adolescent Psychiatry; Action on Hearing Loss (G51); Agence Nationale de la Recherche; Agency for Health Care Policy Research (HS06516); Age UK Research into Ageing Fund; Åke Wiberg Foundation; ALF/LUA Research Grant in Gothenburg; ALFEDIAM; ALK-Abello´ A/S (Hørsholm, Denmark); American Heart Association (13POST16500011, 10SDG269004); Ardix Medical; Arthritis Research UK; Association Diabète Risque Vasculaire; AstraZeneca; Australian Associated Brewers; Australian National Health and Medical Research Council (241944, 339462, 389927, 389875, 389891, 389892, 389938, 442915, 442981, 496739, 552485, 552498); Avera Research Institute; Bayer Diagnostics; Becton Dickinson; Biobanking and Biomolecular Resources Research Infrastructure (BBMRI –NL, 184.021.007); Biocentrum Helsinki; Boston Obesity Nutrition Research Center (DK46200); British Heart Foundation (RG/10/12/28456, SP/04/002); Canada Foundation for Innovation; Canadian Institutes of Health Research (FRN-CCT-83028); Cancer Research UK; Cardionics; Center for Medical Systems Biology; Center of Excellence in Complex Disease Genetics and SALVECenter of Excellence in Genomics (EXCEGEN); Chief Scientist Office of the Scottish Government; City of Kuopio; Cohortes Santé TGIR; Contrat de Projets État-Région; Croatian Science Foundation (8875); Danish Agency for Science, Technology and Innovation; Danish Council for Independent Research (DFF–1333-00124, DFF–1331-007308); Danish Diabetes Academy; Danish Medical Research Council; Department of Psychology and Education of the VU University Amsterdam; Diabetes Hilfs- und Forschungsfonds Deutschland; Dutch Brain Foundation; Dutch Ministry of Justice; Emil Aaltonen Foundation; Erasmus Medical Center; Erasmus University; Estonian Government (IUT20-60, IUT24-6); Estonian Ministry of Education and Research (3.2.0304.11-0312); European Commission (230374, 284167, 323195, 692145, FP7 EurHEALTHAgeing-277849, FP7 BBMRI-LPC 313010, nr 602633, HEALTH-F2-2008-201865-GEFOS, HEALTH-F4-2007-201413, FP6 LSHM-CT-2004-005272, FP5 QLG2-CT-2002-01254, FP6 LSHG-CT-2006-01947, FP7 HEALTH-F4-2007-201413, FP7 279143, FP7 201668, FP7 305739, FP6 LSHG-CT-2006-018947, HEALTH-F4-2007-201413, QLG1-CT-2001-01252); European Regional Development Fund; European Science Foundation (EuroSTRESS project FP-006, ESF, EU/QLRT-2001-01254); Faculty of Biology and Medicine of Lausanne; Federal Ministry of Education and Research (01ZZ9603, 01ZZ0103, 01ZZ0403, 03ZIK012, 03IS2061A); Federal State of Mecklenburg - West Pomerania; Fédération Française de Cardiologie; Finnish Cultural Foundation; Finnish Diabetes Association; Finnish Foundation of Cardiovascular Research; Finnish Heart Association; Food Standards Agency; Fondation de France; Fonds Santé; Genetic Association Information Network of the Foundation for the National Institutes of Health; German Diabetes Association; German Federal Ministry of Education and Research (BMBF, 01ER1206, 01ER1507); German Research Council (SFB-1052, SPP 1629 TO 718/2-1); GlaxoSmithKline; Göran Gustafssons Foundation; Göteborg Medical Society; Health and Safety Executive; Heart Foundation of Northern Sweden; Icelandic Heart Association; Icelandic Parliament; Imperial College Healthcare NHS Trust; INSERM, Réseaux en Santé Publique, Interactions entre les déterminants de la santé; Interreg IV Oberrhein Program (A28); Italian Ministry of Economy and Finance; Italian Ministry of Health (ICS110.1/RF97.71); John D and Catherine T MacArthur Foundation; Juho Vainio Foundation; King's College London; Kjell och Märta Beijers Foundation; Kuopio University Hospital; Kuopio, Tampere and Turku University Hospital Medical Funds (X51001); Leiden University Medical Center; Lilly; LMUinnovativ; Lundbeck Foundation; Lundberg Foundation; Medical Research Council of Canada; MEKOS Laboratories (Denmark); Merck Santé; Mid-Atlantic Nutrition Obesity Research Center (P30 DK72488); Ministère de l'Économie, de l'Innovation et des Exportations; Ministry for Health, Welfare and Sports of the Netherlands; Ministry of Cultural Affairs of the Federal State of Mecklenburg-West Pomerania; Ministry of Education and Culture of Finland (627;2004-2011); Ministry of Education, Culture and Science of the Netherlands; MRC Human Genetics Unit; MRC-GlaxoSmithKline Pilot Programme Grant (G0701863); Municipality of Rotterdam; Netherlands Bioinformatics Centre (2008.024); Netherlands Consortium for Healthy Aging (050-060-810); Netherlands Genomics Initiative; Netherlands Organisation for Health Research and Development (904-61-090, 985-10-002, 904-61-193, 480-04-004, 400-05-717, Addiction-31160008, Middelgroot-911-09-032, Spinozapremie 56-464-14192); Netherlands Organisation for Health Research and Development (2010/31471/ZONMW); Netherlands Organisation for Scientific Research (10-000-1002, GB-MW 940-38-011, 100-001-004, 60-60600-97-118, 261-98-710, GB-MaGW 480-01-006, GB-MaGW 480-07-001, GB-MaGW 452-04-314, GB-MaGW 452-06-004, 175.010.2003.005, 175.010.2005.011, 481-08-013, 480-05-003, 911-03-012); Neuroscience Campus Amsterdam; NHS Foundation Trust; Novartis Pharmaceuticals; Novo Nordisk; Office National Interprofessionel des Vins; Paavo Nurmi Foundation; Påhlssons Foundation; Päivikki and Sakari Sohlberg Foundation; Pierre Fabre; Republic of Croatia Ministry of Science, Education and Sport (108-1080315-0302); Research Centre for Prevention and Health, the Capital Region for Denmark; Research Institute for Diseases in the Elderly (014-93-015, RIDE2); Roche; Russian Foundation for Basic Research (NWO-RFBR 047.017.043); Rutgers University Cell and DNA Repository (NIMH U24 MH068457-06); Sanofi-Aventis; Scottish Executive Health Department (CZD/16/6); Siemens Healthcare; Social Insurance Institution of Finland (4/26/2010); Social Ministry of the Federal State of Mecklenburg-West Pomerania; Société Francophone du Diabète; State of Bavaria; Stroke Association; Swedish Diabetes Association; Swedish Foundation for Strategic Research; Swedish Heart-Lung Foundation (20140543); Swedish Research Council (2015-03657); Swedish Medical Research Council (K2007-66X-20270-01-3, 2011-2354); Swedish Society for Medical Research; Swiss National Science Foundation (33CSCO-122661, 33CS30-139468, 33CS30-148401); Tampere Tuberculosis Foundation; The Marcus Borgström Foundation; The Royal Society; The Wellcome Trust (084723/Z/08/Z, 088869/B/09/Z); Timber Merchant Vilhelm Bangs Foundation; Topcon; Torsten and Ragnar Söderberg's Foundation; UK Department of Health; UK Diabetes Association; UK Medical Research Council (MC_U106179471, G0500539, G0600705, G0601966, G0700931, G1002319, K013351, MC_UU_12019/1); UK National Institute for Health Research BioResource Clinical Research Facility and Biomedical Research Centre; UK National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre; UK National Institute for Health Research (RP-PG-0407-10371); Umeå University Career Development Award; United States – Israel Binational Science Foundation Grant (2011036); University Hospital Oulu (75617); University Medical Center Groningen; University of Tartu (SP1GVARENG); National Institutes of Health (AG13196, CA047988, HHSN268201100046C, HHSN268201100001C, HHSN268201100002C, HHSN268201100003C, HHSN268201100004C, HHSC271201100004C, HHSN268200900041C, HHSN268201300025C, HHSN268201300026C, HHSN268201300027C, HHSN268201300028C, HHSN268201300029C, HHSN268201500001I, HL36310, HG002651, HL034594, HL054457, HL054481, HL071981, HL084729, HL119443, HL126024, N01-AG12100, N01-AG12109, N01-HC25195, N01-HC55015, N01-HC55016, N01-HC55018, N01-HC55019, N01-HC55020, N01-HC55021, N01-HC55022, N01-HD95159, N01-HD95160, N01-HD95161, N01-HD95162, N01-HD95163, N01-HD95164, N01-HD95165, N01-HD95166, N01-HD95167, N01-HD95168, N01-HD95169, N01-HG65403, N02-HL64278, R01-HD057194, R01-HL087641, R01-HL59367, R01HL-086694, R01-HL088451, R24-HD050924, U01-HG-004402, HHSN268200625226C, UL1-RR025005, UL1-RR025005, UL1-TR-001079, UL1-TR-00040, AA07535, AA10248, AA11998, AA13320, AA13321, AA13326, AA14041, AA17688, DA12854, MH081802, MH66206, R01-D004215701A, R01-DK075787, R01-DK089256, R01-DK8925601, R01-HL088451, R01-HL117078, R01-DK062370, R01-DK072193, DK091718, DK100383, DK078616, 1Z01-HG000024, HL087660, HL100245, R01DK089256, 2T32HL007055-36, U01-HL072515-06, U01-HL84756, NIA-U01AG009740, RC2-AG036495, RC4-AG039029, R03 AG046389, 263-MA-410953, 263-MD-9164, 263-MD-821336, U01-HG004802, R37CA54281, R01CA63, P01CA33619, U01-CA136792, U01-CA98758, RC2-MH089951, MH085520, R01-D0042157-01A, MH081802, 1RC2-MH089951, 1RC2-MH089995, 1RL1MH08326801, U01-HG007376, 5R01-HL08767902, 5R01MH63706:02, HG004790, N01-WH22110, U01-HG007033, UM1CA182913, 24152, 32100-2, 32105-6, 32108-9, 32111-13, 32115, 32118-32119, 32122, 42107-26, 42129-32, 44221); USDA National Institute of Food and Agriculture (2007-35205-17883); Västra Götaland Foundation; Velux Foundation; Veterans Affairs (1 IK2 BX001823); Vleugels Foundation; VU University's Institute for Health and Care Research (EMGO+, HEALTH-F4-2007-201413) and Neuroscience Campus Amsterdam; Wellcome Trust (090532, 091551, 098051, 098381); Wissenschaftsoffensive TMO; and Yrjö Jahnsson Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. ; Peer Reviewed
Two years ago on Feb. 24, 2022, the world watched as Russian tanks rolled into the outskirts of Kyiv and missiles struck the capital city. Contrary to initial predictions, Kyiv never fell, but the country today remains embroiled in conflict. The front line holds in the southeastern region of the country, with contested areas largely focused on the Russian-speaking Donbas and port cities around the Black Sea.Russian President Vladimir Putin, having recognized the Russian-occupied territories of Donetsk and Luhansk as independent days before the invasion, has from the beginning declared the war a "special military operation" to "demilitarize and denazify" Ukraine. His goals have alternated, however, between existential — bringing all of Ukraine into the influence of Russia — and strategic — laying claim to only those Russian-speaking areas in the east and south of the country.It is in the latter that Russia has been much more successful. Yet after two winters of brutal fighting and hundreds of thousands of casualties on both sides, as of the end of 2023 Russia only laid claim to 18% of Ukraine's territory, as compared to 7% on the eve of the war and 27% in the weeks after the invasion. Meanwhile, the West's coffers have been opened — and, as some say, drained — to help Ukraine's government, led by President Volodymyr Zelensky, defend itself against Moscow. Regardless, Ukraine's military forces have been wholly depleted as they compete with a much more resourced and populous Russia. While Ukraine's military campaign was able to take advantage of Russian tactical mistakes in the first year, its much-heralded counteroffensive in 2023 failed to provide the boost needed not only to rid the country of the Russian occupation, but also to put Kyiv in the best position to call for terms.If anything, as Quincy Institute experts Anatol Lieven and George Beebe point out in their new brief, "there is now little realistic prospect of further Ukrainian territorial gains on the battlefield, and there is a significant risk that Ukraine might exhaust its manpower and munitions and lay itself open to a devastating Russian counterattack."The only and best solution, they say, is to drive all sides to the negotiating table before Ukraine is destroyed.The narrative of the war — how it began, where it is today — is well documented. On the second anniversary of Russia's full-scale invasion, RS thought it might be instructive to look at the numbers — weapons, aid, polling, population, and more — that illustrate the cost and the contours of the conflict over 24 months, and counting.Money spentThe U.S. Congress has allocated a total of $113 billion in funding related to the war. The vast majority of this money went directly to defending Ukraine ($45.2 billion in military aid) and keeping its government and society functioning ($46 billion in economic and humanitarian aid). Other funds went to rearming allies ($4.7 billion) and expanding U.S. military operations in Europe ($15.2 billion).After two years of war, that funding has dried up. The Biden administration, which once shipped two or three new weapons packages each month, has not sent Ukraine a major arms shipment since Dec. 27, 2023. As Congress struggles to pass an additional $60 billion in Ukraine-related funding, observers increasingly believe that aid package may have been the last.WeaponsThe Pentagon has sent at least 3,097,000 rounds of artillery to Ukraine since Russia's invasion. Most of those (2,000,000) have been 155 mm shells, the standard size used by the U.S. and its NATO allies. For perspective, that's about 95,000 tons of 155 mm ammunition alone.Despite ramping up military manufacturing, the U.S. still only produces about 340,000 155 mm shells per year, meaning that Ukraine has been firing rounds at three times the rate of American production.Washington has also given Kyiv 76 tanks, including 31 Abrams tanks and 45 Soviet-era T-72Bs. Ukraine has received 3,631 American armored vehicles of various types, from infantry fighting vehicles to personnel carriers and medical trucks.Meanwhile, Ukraine has made use of 39 American-made HIMARS, a mobile rocket launcher that has become famous for its utility in the war. As for smaller arms, the U.S. has sent at least 400,000,000 grenades and bullets in the past 24 months.CasualtiesThe war has killed at least 10,378 civilians and injured an additional 19,632, according to the UN. More than three in four non-combatant casualties occurred in areas held by the Ukrainian government, indicating that Moscow is responsible for the lion's share of civilian harm.When it comes to military casualties, good data still remains hard to come by and estimates are sometimes wildly different. Neither Russia nor Ukraine have offered detailed, public indications of the war's impact on their soldiers.The U.S. estimated in August that 70,000 Ukrainian soldiers had died and an additional 100,000 to 120,000 had been injured, putting the number of total casualties at over 170,000. Russia, for its part, claimed in November that 383,000 Ukrainian soldiers had been killed or wounded.On the other side, the United Kingdom estimates that Russia has suffered at least 320,000 casualties, with 50,000 deaths among Russian soldiers and 20,000 deaths among Wagner Group mercenaries. Washington said in December that Moscow had suffered 315,000 casualties, though American officials did not provide a breakdown of deaths and injuries.Ukraine populationThe United Nations estimates that the Ukrainian population (the entire country within internationally recognized borders), which totaled 43.5 million people in 2021, dropped to 39.7 million in 2022 as war swept through the country's east. This trend continued into 2023, as the population dropped to 36.7 million — the lowest level since Ukraine became independent in 1990.As of January, 6.3 million Ukrainians have become refugees abroad, with another 3.7 million displaced internally. As the frontlines have settled, Ukraine's population has slowly started to grow again, reaching 37.9 million in early 2024. Meanwhile, demographer Elena Libanova estimates that only 28 million of those people live within areas currently under Ukrainian government control (outside of Crimea and the Donbas).U.S. pollingTwo new polls that came out within the last week illustrate the complexities of Americans' feelings toward the war in Ukraine and the U.S. role in it.First, a Pew poll published February 16 found that a large majority of Americans (74%) see the war between Russia and Ukraine as somewhat (30%) or very important (43%) to U.S. interests. And another survey, from the Harris Poll and the Quincy Institute, which publishes Responsible Statecraft, found that Americans broadly support a U.S.-led negotiated end to the conflict. But the past few months in Washington have been largely focused on U.S. aid to Ukraine, specifically whether Congress will pass President Biden's request for roughly $60 billion for Kyiv's fight against Russia. According to Pew, in March 2022, 74% of Americans said U.S. aid to Ukraine was "just right" or "not enough." In December 2023, that same survey found that just 47% said the same. The biggest change came from Republicans: 49% said in March, 2022 that U.S. aid was "not enough," while just 13% said the same in December.Meanwhile, Gallup found in August 2022 that 74% of Americans said U.S. aid to Ukraine was "about right" (36%) or "not enough" (38%). Those numbers came down slightly in Gallup's latest track on this question in October, 2023, with 58% saying U.S. aid was about right (33%) or not enough (25%).Peace summitsThere have been several attempts to bring nations together to outline talks to end the war. Russia and Ukraine engaged in five rounds of talks in Belarus and Turkey shortly after the invasion, but the talks collapsed amid allegations of Russian war crimes and Western pressure on Kyiv to keep fighting.Since then, the belligerents have spoken directly about secondary issues, like Black Sea shipping and prisoner swaps. Ukraine, meanwhile, laid out a "10-point peace plan" that has formed the basis for five international summits, none of which included Russia. These took place in Copenhagen, Denmark, in June 2023; in Jeddah, Saudi Arabia, in August 2023; in Malta in October, 2023; in Riyadh, Saudi Arabia, in December 2023; and Davos, Switzerland, in January of this year.CongressSince the start of the war, Congress has passed four aid packages for Ukraine, totaling $113 billion. While none of the four packages were identical and aid for Ukraine was sometimes bundled with other spending, the trends for support for Kyiv in Congress are similar to those we see in polling, particularly among congressional Republicans.The 2022 supplemental, which became law in May 2022 and provided Ukraine with $39.34 billion in aid passed the House 368-57 and the Senate by a vote of 86-11. By September 2023, when the House voted on the Ukraine Security Assistance and Oversight Supplemental Appropriations Act, which provided Kyiv with $300 million in security assistance, it passed by a vote of 311-117, with a majority of Republican members opposing the legislation.On February 12 of this year, the Senate voted 70-29 to pass a national security supplemental, which would provide approximately $60 billion in aid for Kyiv alongside money for Israel and partners in the Indo-Pacific. The bill has not yet been voted on in the House.Ben Armbruster, Blaise Malley, Connor Echols and Kelley Vlahos contributed reporting. Graphics by Khody Akhavi.
AMÉRICA LATINA Miles de brasileños salen a las calles en protestas masivas. Para más información:http://www.lemonde.fr/ameriques/article/2013/06/19/bresil-la-commission-des -droits-de-l-homme-approuve-un-traitement-pour-les-homosexuels_3432430_322 2.htmlhttp://www.nytimes.com/2013/06/19/world/americas/brazilian-leaders-brace-for-moreotests.html?ref=world&_r=0&gwh=F5C24ED264CCA38C603BBD13B470C1FBhttp://www.bbc.co.uk/news/world-latin-america-22961874http://internacional.elpais.com/internacional/2013/06/18/actualidad/1371580181_ 159118.htmlhttp://edition.cnn.com/2013/06/18/world/americas/brazil-protests/index.htm l?hpt=wo_c2http://www.eltiempo.com/mundo/latinoamerica/se-aguara-la-revolucion-del-vinagr e-en-brasil_12879971-4http://www.economist.com/blogs/americasview/2013/06/protests-brazil El máximo tribunal de Argentina veta la reforma judicial kirchnerista. Para más información:http://internacional.elpais.com/internacional/2013/06/18/actualidad/1371586701_ 459857.html Humala deniega el indulto al ex presidente peruano Fujimori. Para más información:http://www.bbc.co.uk/news/world-latin-america-22823488http://internacional.elpais.com/internacional/2013/06/07/actualidad/13706 35226_139709.htmlhttp://edition.cnn.com/2013/06/07/world/americas/peru-fujimori/index.htm l?hpt=wo_bn8http://www.eluniversal.com.mx/internacional/82937.htmlhttp://www.eltiempo.com/mundo/latinoamerica/humala-no-concede-indult o-a-fujimori_12853407-4http://www.bbc.co.uk/news/world-latin-america-22821052 OEA logra primer consenso para abordar diálogos sobre drogas. Para más información:http://www.latimes.com/news/nationworld/world/la-fg-oas-drugs-20130605, 0,3473482.storyhttp://www.eltiempo.com/mundo/latinoamerica/asamblea-de-la-oea-en-guatema la_12849107-4http://internacional.elpais.com/internacional/2013/06/06/actualidad/137055218 6_000263.htmlhttp://www.eltiempo.com/mundo/latinoamerica/oea-abri-va-para-continuar-deb ate-sobre-nuevo-enfoque-de-drogas_12852242-4http://www.eltiempo.com/mundo/latinoamerica/cambio-de-ruta-en-lucha-contr a-la-droga_12856795-4 Reacción dispar en America Latina tras nombramiento de Rice como nueva asesora de seguridad estadounidense. Para más información:http://www.miamiherald.com/2013/06/05/3435679/reaction-muted-among-lati n-un.html#storylink=cpy Juicio por genocidio en Guatemala a Ríos Montt se reanudará en 2014. Para más información:http://www.eltiempo.com/mundo/latinoamerica/juicio-a-ros-montt-se-reanudar -en-2014_12847885-4 El miedo llega al corazón de México: la misteriosa desaparición de 12 jóvenes. Para más información:http://edition.cnn.com/2013/06/08/world/americas/mexico-missing-mystery /index.html?hpt=wo_bn8http://www.bbc.co.uk/news/world-latin-america-22829581 http://www.latimes.com/news/world/worldnow/la-fg-wn-mexico-prison-break -20130609,0,1994844.storyhttp://worldnews.nbcnews.com/_news/2013/05/31/18651848-teen-among-11-kid napped-in-daylight-from-mexico-city-bar?lite Maduro intenta dirigir Venezuela a pesar del desabastecimiento y rumores de división chavista. Para más información:http://www.nytimes.com/aponline/2013/06/09/world/americas/ap-lt-venezuela -election-audit.html?ref=world&gwh=9F4592A312A5BE45B1B7A3EDFA9F2EDAhttp://www.lanacion.com.ar/1590705-maduro-sube-la-apuesta-y-denuncia-otra -conspiracionhttp://www.bbc.co.uk/news/world-latin-america-22829583 La principal universidad de Venezuela paraliza indefinidamente sus actividades. Para más información:http://internacional.elpais.com/internacional/2013/06/07/actualidad/137062596 5_416315.html Según analistas Irán y Hezbollah encuentran en Latinoamérica una mina de ingresos y reclutas. Para más información:http://edition.cnn.com/2013/06/03/world/americas/iran-latin-america/index.html Cuba es escenario de diálogos de paz para Colombia. Para más información:http://www.bbc.co.uk/news/world-latin-america-22853611 La carrera hacia la Casa Rosada irrumpe en el tablero político de Argentina. Para más información:http://internacional.elpais.com/internacional/2013/06/07/actualidad/1370624 610_614080.html Nicaragua apuesta a tener su canal interoceánico. Para más información:http://www.eltiempo.com/mundo/latinoamerica/proyecto-de-canal-interoceanic o-de-nicaragua_12858382-4 Diversos medios hacen referencia a coyuntura económica brasileña. Para más información:http://www.economist.com/news/americas/21579048-feeble-growth-has-for ced-change-course-governments-room-manoeuvre-morehttp://edition.cnn.com/2013/05/30/business/brazil-middle-class-boom/ind ex.html?hpt=wo_bn2 Condenan a cadena perpetua al último líder de Sendero Luminoso en Perú. Para más información:http://internacional.elpais.com/internacional/2013/06/08/actualidad/1370666 114_358936.htmlhttp://www.eltiempo.com/mundo/latinoamerica/cadena-perpetua-para-ltimo-ld er-de-sendero-luminoso_12853905-4 Piden abrir juicio contra 35 militares suramericanos por Plan Cóndor Para más información:http://www.eltiempo.com/mundo/latinoamerica/juicio-a-militares-por-plan-c ondor_12878566-4 El presidente chino Xi intenta estrechar lazos comerciales con México. Para más información:http://www.latimes.com/news/nationworld/world/la-fg-mexico-china-20130 605,0,221993.story ESTADOS UNIDOS /CANADÁ Espionaje en Estados Unidos: un ex empleado de la CIA filtró la información. Para más información:http://www.nytimes.com/2013/06/09/us/politics/officials-say-congress-was-fu lly-briefed-on-surveillance.html?ref=worldhttp://edition.cnn.com/2013/06/10/world/asia/snowden-what-next/index.htm l?hpt=wo_c1http://www.bbc.co.uk/news/world-us-canada-22850901http://www.lemonde.fr/international/article/2013/06/10/ed-snowden-le-lanceu r-d-alerte-qui-defie-obama_3427093_3210.htmlhttp://oglobo.globo.com/mundo/site-brinca-com-programa-secreto-de-monitora mento-nos-eua-8642713#ixzz2Vs87O16b http://www.chinadaily.com.cn/world/2013-06/19/content_16635558.htm Obama y Putin juntos en la cumbre del G8. Para más información:http://www.chinadaily.com.cn/world/2013-06/17/content_16628639.htmhttp://www.nytimes.com/2013/06/19/world/americas/extending-a-hand -abroad-obama-often-finds-a-cold-shoulder.html?ref=world&gwh=14C0D96142432B8CB8485A67D02B6380 Obama nombró a Susan Rice como su nueva asesora de seguridad. Para más información:http://www.eltiempo.com/mundo/estados-unidos/susan-rice-ser-la-nueva-asesora- de-seguridad-de-barack-obama_12846982-4 Estados Unidos relanza las conversaciones de paz con los talibanes en Catar. Para más información:http://internacional.elpais.com/internacional/2013/06/18/actualidad/1371566 115_064096.html Obama nombra a Furman como nuevo jefe económico de la Casa Blanca. Para más información:http://www.chinadaily.com.cn/world/2013-06/11/content_16606433.htm Presidentes de Estados Unidos y China abogan por 'nuevo modelo' de relaciones. Para más información:http://www.economist.com/news/china/21579043-president-xi-jinping-shows-inter est-reviving-ties-america-how-far-he-preparedhttp://www.latimes.com/news/nationworld/world/la-fg-us-china-summit-20130609, 0,5869616.storyhttp://www.nytimes.com/2013/06/09/world/asia/obama-and-xi-try-building-a-new -model-for-china-us-ties.html?ref=worldhttp://www.nytimes.com/2013/06/10/world/asia/obama-and-xi-try-to-avoid-a-col d-war-mentality.html?ref=world Estados Unidos cada vez más cerca de la reforma migratoria. Para más información:http://www.eltiempo.com/mundo/estados-unidos/reforma-migratoria-podra-ser-apr obada-este-ao_12850708-4http://www.bbc.co.uk/news/world-us-canada-22850762http://www.eluniversal.com.mx/internacional/82934.html Escándalo en torno al alcalde de Toronto. Para más información:http://www.chinadaily.com.cn/world/2013-06/18/content_16631857.htmhttp://edition.cnn.com/2013/05/30/world/americas/canada-toronto-mayor/in dex.htmlhttp://worldnews.nbcnews.com/_news/2013/05/30/18634392-embattled-toro nto-mayor-will-run-again-despite-drug-allegations?litehttp://www.bbc.co.uk/news/world-us-canada-22960593 Diversos medios analizan y cuestionan la postura de Estados Unidos frente a los refugiados, los rebeldes y el conflicto sirio. Para más información:http://www.latimes.com/news/nationworld/world/middleeast/la-fg-syria-refugees-20130610,0,6484601.storyhttp://www.eltiempo.com/mundo/estados-unidos/crisis-en-siria_12877505-4http://edition.cnn.com/2013/06/09/politics/white-house-syria/index.html?hpt=wo_c2 EUROPA Rusia bloquea el acuerdo sobre una intervención en Siria. Para más información:http://www.chinadaily.com.cn/world/2013-06/19/content_16635919.htmhttp://internacional.elpais.com/internacional/2013/06/17/actualidad/137150 2103_091990.html Crece la violencia en Turquía por enfrentamientos entre manifestantes y la policía. Para más información:http://internacional.elpais.com/internacional/2013/06/18/actualidad/1371555410 _756638.htmlhttp://www.lemonde.fr/europe/article/2013/06/10/en-turquie-le-processus-de-pai x-kurde-a-l-epreuve-des-manifestations_3426986_3214.htmlhttp://www.lanacion.com.ar/1590256-advertencia-de-erdogan-a-los-manifestanteshttp://edition.cnn.com/2013/06/08/world/pakistan-drones/index.html?hpt=wo_c2http://www.latimes.com/news/nationworld/world/la-fg-police-clash-with-protester s-in-istanbul-20130611,0,6189707.storyhttp://www.eluniversal.com.mx/internacional/82969.htmlhttp://www.bbc.co.uk/news/world-europe-22790635http://www.chinadaily.com.cn/world/2013-06/08/content_16594833.htm http://oglobo.globo.com/mundo/primeiro-ministro-turco-aceita-receber-manifestant es-8646402http://www.economist.com/news/briefing/21579005-protests-against-recep-tayyip- erdogan-and-his-ham-fisted-response-have-shaken-his-rule-and Alemanes y checos vivan las consecuencias de las devastadoras inundaciones. Para más información:http://www.nytimes.com/2013/06/10/world/europe/10iht-flood10.html?ref=worldhttp://www.lanacion.com.ar/1590680-parte-de-alemania-bajo-el-agua#comentarwww.lemonde.fr/europe/video/2013/06/10/la-police-reprime-les-manifestants-a-ankara_3427273_3214.html La centroizquierda italiana logró un triunfo contundente en las municipales. Para más información:http://oglobo.globo.com/mundo/centro-esquerda-recupera-roma-nas-urnas-8647380http://www.lanacion.com.ar/1590681-la-centroizquierda-italiana-logro-un-triunfo-co ntundente-en-las-municipales Suiza se encierra en sus miedos y endurece su ley de asilo. Para más información:http://internacional.elpais.com/internacional/2013/06/07/actualidad/137063251 4_643009.htmlhttp://www.eltiempo.com/mundo/europa/ley-de-asilo-en-suiza_12860089-4http://internacional.elpais.com/internacional/2013/06/09/actualidad/1370806897_ 177919.html Los programas electorales muestran que los partidos alemanes coinciden en los recortes. Para más información:http://internacional.elpais.com/internacional/2013/06/08/actualidad/1370722970_ 157146.html Putin apoyará prohibición de adopción a parejas homosexuales en Rusia. Para más información:http://www.eltiempo.com/mundo/europa/prohibicin-de-adopcin-a-parejas-ho mosexuales-en-rusia_12844610-4http://www.nytimes.com/2013/06/09/world/europe/trial-sendss.html?ref=wo rld&_r=0 París se plantea disolver los grupos violentos de extrema derecha tras asesinato de militante comprometido en la defensa de los homosexuales. Para más información:http://www.eltiempo.com/mundo/europa/pars-se-plantea-disolver-los-grupos -violentos-de-extrema-derecha_12850632-4 http://internacional.elpais.com/internacional/2013/06/06/actualidad/1370547 423_977824.htmlhttp://internacional.elpais.com/internacional/2013/06/06/actualidad/13704794 17_014580.html El Asad advierte a Europa de que pagará las consecuencias si arma a los rebeldes. Para más información:http://internacional.elpais.com/internacional/2013/06/18/actualidad/13 71546210_225136.html "El País" de España analiza: "Ni Grexit ni Grecovery". Para más información:http://internacional.elpais.com/internacional/2013/06/09/actualidad/1370799 092_688308.html ASIA- PACÍFICO/ MEDIO ORIENTE Elecciones en Irán: apatía y lucha de poder. Para más información:http://www.economist.com/blogs/pomegranate/2013/06/iran-s-electionhttp://edition.cnn.com/2013/06/15/world/meast/iran-rouhani-profile/inde x.html?hpt=wo_c2http://www.eltiempo.com/mundo/medio-oriente/relaciones-iran-con-estados -unidos_12875543-4http://www.chinadaily.com.cn/world/2013-06/08/content_16591014.htmhttp://edition.cnn.com/2013/06/09/world/meast/iran-nuclear-reactor/index. html?hpt=wo_bn11http://www.latimes.com/news/nationworld/world/middleeast/la-fg-iran-elections-20130611,0,3357264.story http://www.latimes.com/news/nationworld/world/middleeast/la-fg- iran-elections-20130611,0,3357264.storyCumbre del G8 sin acuerdo sobre guerra en Siria. Para más información:http://www.nytimes.com/2013/06/19/world/europe/g-8-meeting-ends-wit h-cordial-stalemate-on-syria.html?ref=world&gwh=325D51A100831D8E95 A7CDA8915C9A27http://www.eltiempo.com/mundo/europa/cumbre-del-g8-evalua-conflicto-en- siria_12877428-4 Continúa la escalada de violencia en Siria. Para más información:http://www.economist.com/news/middle-east-and-africa/21579055-fall-qusayr -boost-regime-far-decisive-turning-pointhttp://worldnews.nbcnews.com/_news/2013/06/10/18883427-reuters-us-wei ghs-arming-syria-rebels?litehttp://www.lemonde.fr/proche-orient/visuel/2013/05/23/iran-portraits-de-candidats_3386947_3218.htmlhttp://www.nytimes.com/2013/06/09/world/middleeast/syria-opposition-won t-attend-talks-unless-rebels-get-arms-commander-says.html?ref=worldhttp://www.miamiherald.com/2013/05/30/3425004/syrias-assad-pledges-to -attend.html#storylink=cpyhttp://www.bbc.co.uk/news/world-middle-east-22852957Mueren 46 personas en atentado contra un funeral en Pakistán. Para más información:http://www.eltiempo.com/mundo/asia/atentado-contra-un-funeral-en-pakis tn_12878029-4 Son más de 511000 sirios refugiados en el Líbano. Para más información:http://www.chinadaily.com.cn/world/2013-06/09/content_16600893.htm La ONU pide 3920 millones para ayudar a las víctimas de la guerra en Siria. Para más información:http://internacional.elpais.com/internacional/2013/06/07/actualidad/137060 4074_343489.html La premio Nobel de la Paz Suu Kyi reconoce su deseo de ser presidenta de Myanmar. Para más información:http://edition.cnn.com/2013/06/06/world/asia/myanmar-suu-kyi-presidential-aspiration/index.html?hpt=wo_c2http://internacional.elpais.com/internacional/2013/06/06/actualidad/13705097 70_497091.html Tras largas conversaciones las dos Coreas acuerdan encuentro. Para más información:http://www.chinadaily.com.cn/world/2013-06/10/content_16602536.htmhttp://www.nytimes.com/2013/06/10/world/asia/north-and-south-korea-to-di scuss-restoring-economic-and-other-ties.html?ref=worldhttp://www.latimes.com/news/world/worldnow/la-fg-wn-north-korea-changes- course-20130606,0,2868588.storyhttp://internacional.elpais.com/internacional/2013/06/09/actualidad/137074 4334_514863.htmlhttp://edition.cnn.com/2013/06/08/world/asia/koreas-tensions/index.html?hp t=wo_c2 Ataque suicida en el aeropuerto de Kabul. Para más información:http://www.lemonde.fr/asie-pacifique/article/2013/06/10/afghanistan-attaque- suicide-d-insurges-pres-de-l-aeroport-de-kaboul_3426919_3216.htmlhttp://www.latimes.com/news/nationworld/world/la-fg-afghan-bombs-201306 04,0,2665212.storyhttp://www.chinadaily.com.cn/world/2013-06/10/content_16603337.htmhttp://www.nytimes.com/2013/06/09/world/asia/attacker-in-afghanistan-hid -bomb-in-his-body.html?ref=world&gwh=A020FB85D7BBAF85C119B695F4D126F9 Crisis en Irak: ataques dejan docenas de muertos por día. Para más información:http://worldnews.nbcnews.com/_news/2013/06/10/18887438-day-long-attack s-kill-more-than-70-in-iraq?litehttp://www.latimes.com/news/world/worldnow/la-fg-wn-iraq-deadly-bomb-a ttacks-20130610,0,2919168.story La oposición india aprende de sus errores. Para más información:http://www.economist.com/blogs/banyan/2013/06/india-s-oppositionwww.lemonde.fr/asie-pacifique/article/2013/06/10/inde-un-nationaliste-hin dou-a-la-tete-de-l-opposition_3426921_3216.htmlhttp://www.latimes.com/news/world/worldnow/la-fg-wn-split-indian-opp osition-party-20130610,0,7283558.storyhttp://www.bbc.co.uk/news/world-asia-india-22851915 Austria retirará a sus 380 cascos azules de la zona desmilitarizada en el Golán. Para más información:http://internacional.elpais.com/internacional/2013/06/06/actualidad/1370503 365_774581.htmlhttp://www.latimes.com/news/world/worldnow/la-fg-wn-syria-golan-un-mission-20130606,0,6454723.story Palestina inaugura gobierno en un momento crítico para el proceso de paz. Para más información:http://www.latimes.com/news/nationworld/world/middleeast/la-fg-palestin ian-premier-20130603,0,549411.storyhttp://internacional.elpais.com/internacional/2013/06/09/actualidad/1370 781086_914560.html ÁFRICA Salud de Mandela mantiene al mundo en vilo. Para más información:http://www.chinadaily.com.cn/world/2013-06/11/content_16606127.htmhttp://www.lemonde.fr/afrique/article/2013/06/10/inquietudes-sur-l-etat-de -sante-de-nelson-mandela_3427099_3212.html Reino Unido compensará con 23 millones de euros a los Mau Mau de Kenia. Para más información:http://www.latimes.com/news/nationworld/world/la-fg-britain-kenya-compensate-20130607,0,2322515.storyhttp://www.eltiempo.com/mundo/africa/reino-unido-pagar-23-millones-de-euros- a-los-mau-mau-de-kenia_12849864-4 Aumenta la presencia de Al Qaeda en África Sahariana. Para más información:http://www.miamiherald.com/2013/05/28/3420983/ap-exclusive-rise-of-al- qaida.html Libia vive violentas protestas. Para más información:http://www.nytimes.com/2013/06/10/world/africa/libyan-violence-threatens-t o-undercut-power-of-militias.html?ref=world Tensión entre Sudán y Sudán del Sur. Para más información:http://edition.cnn.com/2013/06/08/world/africa/sudan-oil/index.html?hpt=wo _bn10+http://www.chinadaily.com.cn/world/2013-06/17/content_16628556.htm OTRAS NOTICIAS El G8 apoya medidas de transparencia financiera y contra la evasión fiscal. Para más información:http://www.chinadaily.com.cn/world/2013-06/18/content_16631685.htmhttp://internacional.elpais.com/internacional/2013/06/18/actualidad/1371568829 _378574.htmlhttp://www.economist.com/news/international/21579452-britains-leader -envisages-world-tax-compliance-and-clear-corporate-ownership Fin de pobreza extrema debe ser nuevo objetivo mundial para 2030: ONU. Para más información:http://www.eltiempo.com/mundo/estados-unidos/la-onu-dice-que-el-fin-de-l a-pobreza-extrema-debe-ser-nuevo-objetivo-mundial-para-2030_12845943-4 "Los Angeles Times" presenta portal sobre el crecimiento de la población mundial. Para más información:http://www.latimes.com/news/nationworld/world/population/ "The Economist" presenta su informe semanal: "Business this week". Para más información:http://www.economist.com/news/world-week/21579066-business-week
his doctoral thesis is focused on the increasing importance of mutual funds as saving vehicles for the finances of individuals in the economies of developed countries over the last half of the twentieth century. Among them, the equity funds that take the form of open-end funds like mutual funds are becoming one of the most relevant instruments. Mutual funds collect money from investors and invest it in stocks, bonds, other funds, and so on, and their performance depends on the mix of the allocated securities. Its main objectives were to contribute to the topic of the Active Share (AS) as applied to mutual funds in Eurozone countries. This investigation was mainly motivated by the need to analyse how both the level of concentration of the benchmarks and the level of concentration of the mutual fund industries in the Eurozone affect active management. Due to the scarce number of studies focused on this topic in Europe our results have relevant implications to investors, market supervisors, and policymakers. In Chapter 1, we analysed how article 52 in Directive 2009/65/EC (UCITS IV) on risk of portfolio diversification could distort the accuracy of AS due to the higher level of concentration in Eurozone domestic benchmarks. In this chapter, we were able to identify truly active management in Eurozone mutual funds. Thus, we developed an algorithm to capture the spurious AS (sAS), which is defined as the minimum AS, that is not a consequence of active decisions made by equity fund managers. The results provide evidence that the Directive negatively influences the accuracy of the AS shown for managers who work with very concentrated domestic Eurozone benchmarks such as the PSI 20 (Portugal), ATX 20 (Austria), and IBEX 35 (Spain). In contrast, the evidence from the sAS for the least concentrated domestic Eurozone benchmarks shows that AS reported by managers who work in France, Germany, and Finland are much more accurate. Hence, these results prove that direct AS comparisons in the Eurozone are not feasible and lead us to obtain three AS thresholds per domestic equity benchmark, which are the minimum values of AS needed to confirm that domestic equity funds are significantly active at 90%, 95%, and 99% confidence levels. We also analysed the level of active management in the domestic equity funds registered in each Eurozone country. Our findings also show that the high concentration level and the heterogeneity present in the domestic equity funds in the Eurozone prevent the direct comparability of the AS. Therefore, we had to consider the level of AS over the spurious level and the characteristics of each market that produces significant and different styles of active management. For that, we formulated an actual active share (aAS) that considered the level of concentration in the domestic equity funds of the Eurozone markets and the limits of the portfolio concentration on European regulation. We define aAS as the difference between the monthly AS obtained for each domestic equity fund minus its monthly AS threshold obtained previously at 90%, 95%, and 99% confidence levels. Focusing on the most relevant mutual fund industries in the Eurozone countries, we find that France is the most active domestic equity fund market. Spanish and Italian markets also show high levels of actual active management despite the large concentration in their domestic benchmarks. Conversely, domestic equity funds registered in Germany show lower levels of active management. Our research results support the hypothesis that aAS corrects the potential bias in the original AS caused by both the domestic benchmark concentration and the EU portfolio diversification rules. In summary, our study is the first to evaluate the consequences of both the assorted characteristics of domestic Eurozone benchmarks and the European regulation that prevents portfolio concentration (UCITS IV) in the appropriate estimation of AS. Furthermore, our study identifies truly active management in domestic equity funds in the Eurozone markets. This chapter has important implications for policymakers and practitioners of the domestic equity funds in the Eurozone. In the strongly regulated European markets, our unbiased approach allows both investors and market supervisors to identify the accurate levels of active management of each industry after considering both the regulation of portfolio diversification and the concentrated domestic equity benchmarks. Market supervisors will have a better picture of the active management map to develop appropriate regulations for the mutual fund industry. In addition, our approach should help practitioners and investors to effectively find out the level of active management of domestic equity funds and therefore provide information for fund management companies to replace actual performing managers. Further, our results should help to reduce the opacity in the management fees that funds charge by providing accurate measures of active management. In Chapter 2, we analysed how some market and fund characteristics play a crucial role in explaining the portfolio concentration default on Directive 2009/65/EC (UCITS IV). This chapter should help market supervisors to improve the monitoring process of defaults by domestic equity funds in the Eurozone mutual fund industries. On the one hand, the origin of UCITS directives was considered the beginning towards market protection and increased transparency in the Eurozone. On the other hand, the structure of mutual funds allows retail investors to access sophisticated active strategies that comply with liquidity and transparency restrictions protected by regulatory oversight. Their rules are based on a certain degree of portfolio diversification with the goal of reducing their vulnerability to portfolio risks. This chapter is the first to analyse how concentrated strategies could lead to non-compliance with article 52 in UCITS IV. First, we analysed several market characteristics that may influence the probability of a fund manager failing to meet the portfolio concentration limits. Using a logic panel data model (fixed effects), we estimated the probability of incurring defaults. Our findings provide evidence that should lead market supervisors to pay attention to concentrated fund industries with concentrated domestic benchmarks to prevent defaults on Eurozone concentration limit. The level of concentration of the domestic equity benchmarks would make the defaults almost twice as likely to occur. The level of concentration of the domestic fund industry also has positive and significant effects on the likelihood of incurring defaults. That is, defaults are approximately 12% to 17% more likely to occur when the level of concentration in the domestic fund industry increases. This evidence is consistent with the findings in the literature that link competition with active management strategies such as concentrated portfolios (see Dyck et al., 2013). Second, in the same line of Chapter 1, we analysed several funds characteristics that may influence the probability of a fund manager failing to meet the portfolio concentration limits. In Eurozone markets, market supervisors should especially monitor the most experienced funds that are solo-managed to prevent portfolio weights over the 10% limit. This finding is in accordance with Goldman et al., (2016) who shows that individual managers have much more concentrated portfolios than management teams. The fund's age has a positive and significant influence on the likelihood of defaults. That is, the probability of incurring defaults is approximately 18% to 26% higher among older funds. Thus, this evidence is in accordance with the literature that links older funds with higher levels of idiosyncratic risk as a consequence of having more concentrated portfolios (see Amihud and Goyenko, 2013). Further, we analysed the characteristics of those stocks that were especially subject to more concentrated strategies and, therefore, more vulnerable to mutual funds' investment policies. For that, we applied a multinomial logic panel data model (fixed effects) and found that the weight of the stocks in their benchmarks had a positive and significant effect on default on the EU portfolio concentration limit. The results show how the probability of a stock being subject to default is approximately 8% to 25% higher when the stock weight in the domestic benchmark increases. Thus, market supervisors should monitor stocks with large weights in domestic equity benchmarks. In addition, we also find how the stocks of domestic benchmarks that have been held longer are likely to be subject to concentration defaults. That is, defaults are approximately 13% to 24% more likely to occur when choosing stocks that belong to the benchmarks during the last 24 months. Thus, this result is consistent with the literature that argues the local advantage of reducing information asymmetry problems. Thus, we find how stocks that present low volatility have a greater likelihood of being subject to non-compliance with EU portfolio concentration limits. In terms of percentages, the probability approximately lowers between 19% to 27% when stock volatility increases. This finding is in accordance with the commitment to controlled risk strategies (see Huang et al., 2011). Therefore, market supervisors should pay more attention to these stock characteristics to monitor stocks that are more frequently overweighted above EU concentration limits. In summary, this chapter is the first to both analyse and identify the determinants of domestic equity funds' failure to comply with the portfolio concentration limits of EU Directive 2009/65/EC. Furthermore, our study also determines the characteristics of the stocks subject to these non-compliant portfolios in domestic equity funds in the Eurozone. This chapter has important implications for market supervisors and policymakers in the mutual fund industries of the Eurozone. Our approach allows market supervisors with limited resources to identify and control non-compliant domestic equity funds by monitoring only some fund-specific characteristics. The improvement of this monitoring process should contribute to the financial stability of the EU asset management industry in terms of investor protection and market transparency. That is, mutual fund unitholders should be completely certain that their money is allocated to portfolios fulfilling the concentration limits required by the EU. Our findings also show a tool to assist EU market supervisors in identifying some explanatory mechanisms for stock weights that are over the EU concentration limits. Thus, our results may help supervisors identify what kind of domestic equity funds are more inclined to default and what kind of stocks are likely overweighted by these funds. Market supervisors could especially monitor these stocks to verify that domestic equity funds are meeting the concentration limits. Market supervisors should focus their limited resources on these types of stocks held by domestic equity funds to prevent defaults in portfolio concentration. Finally, our approach could also help retail investors control their risk profiles in terms of exceeding portfolio concentration limits. This application is in line with the reinforcement of investor protection of portfolio concentration. Investors could be sure that domestic equity funds fully follow the diversification requirements and market transparency provided by the UCITS directives. Chapter 3 presents a new perspective in the analysis of active management. We introduced dynamism by proposing a new version of AS that considers how the managers deviate their portfolios in two consecutive periods. We define dynamic Active Share (dAS) as a measure to capture over time the actual level of activity by comparing the differences against the benchmark in two consecutive periods. Our measure captures not only the long and short static positions in each stock included in the benchmark but also the previous long (short) positions that have been overweighted (underweighted) in the next period. Thus, dAS allows us to divide between investment decisions driven to spread portfolio weights closer to the benchmark (i.e., decisions that lead to a lower differentiation to the benchmark) and the other which is further from the benchmark (i.e., decisions that lead to a higher differentiation). Focusing on the most relevant fund industries in the Eurozone, we analysed the predictive power of AS first. The best results were found in the Spanish industry and, with less robustness, in Germany, the Netherlands, Austria, and Belgium. France only shows this relationship in the long term when we consider the CAPM alpha; while Italy, Finland, Portugal, and Greece fail to offer significant results or even present negative relationships. These results indicate that the prediction ability of AS presents assorted results as this relation is less clear than that presented in the literature (Cremers and Petajisto, 2009) Second, we examined the influence on the prediction power for performance of AS by splitting stocks in the portfolios of our sample into benchmark and non-benchmark . The results allow us to identify how the high proportion of prediction ability for performance of AS is explained by the investment in non-benchmark stocks. Although the AS's share of overweight or underweight benchmark stocks is really related to stock picking ability, investing in overweighted stocks may mean distortions in their performance evaluations that can lead to spurious contributions to portfolio performance. Third, we applied and analysed the predictive power of dAS. The results provided evidence that the performance of non-benchmark stocks in high AS funds did not extend to mutual funds with high dAS. Thus, this measure is less sensitive to the weight of the portfolio that is invested in non-benchmark securities that is very relevant in Eurozone countries where domestic benchmarks are highly concentrated. The main advantage of the dAS compared to the AS is that our measure provides more information and can be split according to different investment decisions. For that reason, we proposed splitting up the dAS to examine which trading decisions add value to the portfolio. Our most interesting results showed that German funds presents a robust relationship between selling investment decisions and subsequently better performance. This relationship was also found for Dutch, Austrian, and Portuguese funds but with actual limited significance. This finding is in accordance with the level of activity showed by these industries in Chapter 1. Further, we analysed the contributions to dAS that was generated by those trading decisions that might be considered as managers' bets. These bets could be those decisions that increased holdings that were already overweighted (buy bets) or decrease those holdings that were already underweighted (sell bets). Our findings show as in Germany and in some cases in the Austrian and Portuguese industries that there is subsequent significantly better performance in buying decisions. Focusing on selling decisions, only Finnish funds show positive and strong beliefs and performance. The results for predicting performance show that those portfolios with a higher concentration of these bets offer subsequent abnormal returns as this prediction ability is even higher than the seminal AS in some of the markets in this study. Accordingly, the results shown in this chapter are an interesting addition to Cohen et al. (2010) who try to identify the trades in which the managers have more confidence. The empirical findings show that those mutual funds with trading decisions with a stronger belief from the manager (i.e., decisions that lead them to deviate even more from the benchmark) outperform the remaining funds, especially when buying decisions are considered. This evidence is consistent with Karoui and Patel (2020) who show that the benefit of AS lies in the selection decision rather than the weighting decision. In summary, Chapter 3 is the first to introduce a dynamic perspective on AS to capture managers' activity and skill. This chapter is relevant for investors who should be interested in knowing whether their fund manager is active and whether their decisions on new investment opportunities add value to the portfolio (i.e., undervalued assets) or on the contrary, the fund manager is passive. The common argument is related to the fees because the management fees charged by these two types of funds should be different. In addition, the chapter is also relevant to regulators in order to adjust the management fees charged by management companies to the actual level of activity carried out by mutual funds. Several fields for further investigation have been identified in this dissertation. Regarding the EU Directive, an extensive test of the level of enforcement that the UCITS IV has implemented in each Eurozone country (including emerging markets) could be useful for making decisions about possible changes in the regulation. Furthermore, a complementary analysis of chapter VII in UCITS IV in terms of its appropriateness with the characteristics of each Eurozone country could allow a more complete assessment of the limits of portfolio concentration and the implementation of the protection to investors. In addition, this dissertation makes an important advance in the topic of active management to help further an analysis in other areas or regions with similar characteristics that could be relevant to the financial literature.
The impacts of climate change are felt worldwide and manifest differently in various parts of the globe. While extreme weather events such as monsoons, hurricanes, torrential rains, wildfires, droughts and heat waves with the resulting impacts on human lives and settlements are common, climate change also manifests in slow onset events such as sea level rise, increasing temperatures, ocean acidification, glacial retreat, salinization, land and forest degradation, loss of biodiversity, and desertification. It is found by the United Nations Framework Convention on Climate Change (UNFCCC) that the adverse effects of slow onset events are already affecting developing countries, resulting in loss of fertile land and the scarcity of water resources. In many parts of developing countries where farming constitutes the main livelihood and source of income, changes in the natural environment and in the distribution and availability of water resources may induce social disturbances that may range from migration to social instability and even violent conflicts. Lake Chad Basin and Northeast Nigeria in particular are seen as a climate hot spot partially due to the high variability of precipitations in the region. The Lake Chad that offers livelihood to millions of people in the region has been highly affected by climate change, losing up to 90% of its size between the early 1960s and today. Political issues have also emerged in the region with the birth of the islamist insurgent group Boko Haram in 2009. Since then, social structures have been highly disturbed, with millions of people leaving their homes in search of safety and the fulfilment of their basic needs, therefore becoming Internally Displaced Persons (IDPs) in their countries or crossing the border to become refugees in neighbouring countries. While the insurgency of the Boko Haram group and the response by various governments of the Lake Chad region including Nigeria, Cameroon, Chad and Niger may seem to be the main cause of migration in the region, understanding migration in the Lake Chad Basin is made complex for a few reasons: on the one hand, the link between conflict and migration is easily made by conflict experts; on the other hand, environmental scientists easily establish a correlation between environmental degradation and migration. Meanwhile, conflict and environmental degradation have not been treated simultaneously as causes of migration. To close this gap, this thesis divides into four studies, in which a multitude of research methods and empirical data are used. After the analysis of historical, socioeconomic and the environmental root causes of the crisis in northeast Nigeria in the first study, the second study introduces a comparative analysis of political factors (the conflict) and environmental factors (loss of fertile land and water scarcity) as causes of migration in northeast Nigeria. More explicitly, the role that environmental factors play on migration is dissociated from the role that conflict plays on migration in the study area. The next study examines how water scarcity contributes to migration in the region by studying the association between the local residents' intention to migrate and water related factors. Furthermore, since migration creates new social structures, the last study introduces a Social Network Analysis (SNA) of IDPs in Maiduguri. This approach allows to understand the networks in which IDPs are involved in Maiduguri, the main city in northeast Nigeria where most IDPs are found. It also allows to predict the potential of tensions between IDPs and host communities in the long term. To better address these issues, 204 IDPs in the Bakassi IDP camp located in Maiduguri, 100 members of the host community in the close proximity with the Bakassi IDP camp and experts in various governmental, non-governmental and international organizations based in Nigeria were interviewed. Findings reveal that conflict is the main push factor of migration in the region. However, the time of migration or the time that people spent in conflict before migrating varies from one community to another community. While in some communities people migrated very early after the community was affected by the conflict or even before conflict arrived, in other communities, people stayed several months or years with the conflict before migrating. Findings in this study also reveal that other factors including income, land ownership, occupation, and history of previous resource scarcity have a medium to large effect on the time of migration in some of the communities. Furthermore, the SNA in the Bakassi IDP camp and the host community reveal that the relationships between IDPs within the Bakassi IDP camp were usually friendly, while only few relationships between IDPs and host community members were reported. Host community members were connected to IDPs in other camps far away from their community rather than IDPs in the Bakassi IDP camp that was closer to them. This behaviour is seen in the fourth study in this thesis as a way of securing the few available resources and income generating opportunities that are available to the host community. Even though the network of friendly relationships between IDPs and host community members is denser than the network of conflicting relationships, suggesting a dominance of friendly relationships in the community, most experts believe that the friendly nature of the relationships between IDPs and their host communities may quickly turn conflicting or even violent as the pressure on resources grows and the IDPs population keeps rising. In conclusions, solving the crisis in the Lake Chad Basin and especially in northeast Nigeria is a complex task to the Lake Chad Basin governments, given the complexity of the crisis itself. Besides efforts by the international community to reduce greenhouse gases emissions in order to mitigate global warming and reduce the impact on vulnerable regions such as the Lake Chad Basin, local efforts are needed in the short and long term to address the crisis in the Lake Chad Basin. In the short term, improving humanitarian assistance to IDPs and extending it to poorer households in host communities will not only reduce pressure on the resources in the host communities, but also reduce the potential of tensions between IDPs and members of host communities. In the long term, creating additional income generating opportunities by industrializing the region will reduce the chronic poverty that pushes many young people to join armed groups. The protection of water resources through the construction of boreholes and the regulation of irrigation activities will ensure a sustainable use of water and increase food security in the region. ; Die Auswirkungen des Klimawandels sind weltweit spürbar und manifestieren sich unterschiedlich in verschiedenen Teilen der Erde. Während extreme Wetterereignisse wie Monsun, Wirbelstürme, sintflutartige Regenfälle, Waldbrände, Dürren und Hitzewellen mit den daraus resultierenden Auswirkungen auf Menschenleben und Siedlungen weit verbreitet sind, zeigt sich der Klimawandel auch in langsam einsetzenden Ereignissen wie dem Anstieg des Meeresspiegels, steigenden Temperaturen, Versauerung der Ozeane, Rückzug der Gletscher, Versalzung, Land- und Walddegradierung, Verlust der biologischen Vielfalt und Wüstenbildung. Die Klimarahmenkonvention der Vereinten Nationen (UNFCCC) stellt fest, dass die nachteiligen Auswirkungen langsam einsetzender Ereignisse die Entwicklungsländer bereits treffen und zum Verlust von fruchtbarem Land und zur Verknappung von Wasserressourcen führen. In vielen Teilen der Entwicklungsländer, in denen die Landwirtschaft die wichtigste Lebensgrundlage und Einkommensquelle darstellt, können Veränderungen in der natürlichen Umwelt sowie in der Verteilung und Verfügbarkeit von Wasserressourcen Auswirkungen auf das soziale Gefüge haben und zu Migration, sozialer Instabilität und gewaltsamen Konflikten führen. Insbesondere die Lake Tschad Region und der Nordosten Nigerias gelten als klimatische Brennpunkte. Dies ist teilweise auf die hohe Variabilität der Niederschläge in der Region zurückzuführen. Der Tschadsee, der Millionen von Menschen in der Region eine Lebensgrundlage bietet, wurde vom Klimawandel stark in Mitleidenschaft gezogen und verlor zwischen dem Anfang der 60er Jahre und heute bis zu 90% seiner Größe. Mit dem Erstarken der islamistischen Rebellengruppe Boko Haram im Jahr 2009 sind in der Region auch politische Fragen aufgeworfen worden. Seither sind die sozialen Strukturen in hohem Maße gestört, da Millionen von Menschen auf der Suche nach Sicherheit und der Befriedigung ihrer Grundbedürfnisse ihre Heimat verlassen und deshalb zu Binnenvertriebenen (engl. Internally Displaced Persons - IDPs) in ihren Ländern werden oder die Grenze überqueren, um als Geflüchtete in die Nachbarländer zu gelangen. Während der Aufstand der Boko-Haram-Gruppe und die Reaktion verschiedener Regierungen der Lake Tschad-Region, darunter Nigeria, Kamerun, Tschad und Niger, als Hauptursache für die Migration in der Region erscheinen mögen, wird das Verständnis der Migration in der Lake Tschad Region aus mehreren Gründen kompliziert: Einerseits wird eine klare Verbindung zwischen Konflikt und Migration von Konfliktexperten gesehen; andererseits stellen Umweltwissenschaftler einen Zusammenhang zwischen Umweltzerstörung und Migration her. Jedoch sind Konflikt und Umweltzerstörung bisher nicht zusammen als Ursachen von Migration behandelt worden. Um diese Lücke zu schließen, ist diese Arbeit in vier Studien unterteilt. Nach der Analyse der historischen, sozioökonomischen und umweltbedingten Ursachen der Krise im Nordosten Nigerias in der ersten Studie führt die zweite Studie eine vergleichende Analyse der politischen Faktoren (der Konflikt) und der Umweltfaktoren (Verlust von fruchtbarem Land und Wasserknappheit) als Ursachen der Migration im Nordosten Nigerias ein. Dabei wird die Rolle, die Umweltfaktoren bei der Migration spielen, expliziter von der Rolle abgegrenzt, die der Konflikt für die Migration im Untersuchungsgebiet spielt. In der nächsten Studie wird untersucht, wie Wasserknappheit zur Migration in der Region beiträgt, indem der Zusammenhang zwischen der Migrationsabsicht der Einheimischen und wasserbezogenen Faktoren untersucht wird. Da Migration zudem neue soziale Strukturen schafft, führt die letzte Studie eine soziale Netzwerkanalyse (SNA) der Binnenvertriebenen in Maiduguri ein. Dieser Ansatz ermöglicht es, die Netzwerke zu verstehen, in die die Binnenflüchtlinge in Maiduguri eingebunden sind und das Potenzial von Spannungen zwischen Binnenflüchtlingen und Aufnahmegemeinschaften langfristig vorherzusagen. Zu diesem Zweck befragte ich 204 Binnenvertriebene im Binnenvertriebenenlager Bakassi in Maiduguri, 100 Mitglieder der Gastgemeinde in unmittelbarer Nähe des Binnenvertriebenenlagers Bakassi sowie Experten verschiedener staatlicher, nichtstaatlicher und internationaler Organisationen mit Sitz in Abuja, der Hauptstadt Nigerias. Die Ergebnisse zeigen, dass der Konflikt der wichtigste Push-Faktor für Migration in der Region ist. Die Zeit der Migration oder die Zeit, die Menschen vor der Migration im Konflikt verbrachten, variiert jedoch von einer Gemeinschaft zur anderen Gemeinschaft. Während in einigen Gemeinschaften die Menschen schon sehr früh migrierten, nachdem die Gemeinschaft von dem Konflikt betroffen war oder sogar bevor der Konflikt eintraf, blieben die Menschen in anderen Gemeinschaften mehrere Monate oder Jahre innerhalb des Konfliktkontextes, bevor sie migrierten. Die Ergebnisse dieser Studie zeigen auch, dass andere Faktoren wie Einkommen, Landbesitz, Besatzung und die Geschichte früherer Ressourcenknappheit in einigen der Gemeinschaften einen mittleren bis großen Einfluss auf den Zeitpunkt der Migration haben. Darüber hinaus zeigt die Analyse des sozialen Netzwerks im Binnenflüchtlingslager Bakassi und der Gastgemeinde, dass die Beziehungen zwischen den Binnenflüchtlingen innerhalb des Binnenflüchtlingslagers von Bakassi in der Regel freundschaftlich waren, während nur über wenige Beziehungen zwischen Binnenflüchtlingen und Mitgliedern der Gastgemeinde berichtet wurde. Die Mitglieder der Gastgemeinde standen eher mit Binnenvertriebenen in anderen Lagern in Verbindung, die weit von ihrer Gemeinde entfernt waren, als mit Binnenvertriebenen in dem ihnen näher gelegenen Binnenflüchtlingslager Bakassi. Dieses Verhalten wird in der vierten Studie dieser Arbeit als eine Möglichkeit gesehen, die wenigen verfügbaren Ressourcen und Einkommensmöglichkeiten, die der Gastgemeinde zur Verfügung stehen, zu sichern. Auch wenn das Netz der freundschaftlichen Beziehungen zwischen Binnenvertriebenen und Mitgliedern der Gastgemeinde dichter ist als das Netz der konfliktreichen Beziehungen, was auf eine Dominanz freundschaftlicher Beziehungen in der Gemeinde hindeutet, glauben die meisten Experten, dass der freundschaftliche Charakter der Beziehungen zwischen Binnenvertriebenen und ihren Gastgemeinden mit zunehmendem Druck auf die Ressourcen und steigender Zahl der Binnenvertriebenen schnell in konfliktreiche oder sogar gewalttätige Beziehungen umschlagen könnte. Zusammenfassend ist die Lösung der Krise in der Lake Tschad Region und insbesondere im Nordosten Nigerias angesichts der Komplexität der Krise selbst eine komplexe Aufgabe für die Regierungen in der Lake Tschad Region. Neben den Bemühungen der internationalen Gemeinschaft, die Treibhausgasemissionen zu reduzieren, um die globale Erwärmung einzudämmen und die Auswirkungen auf gefährdete Regionen wie der Lake Tschad Region zu verringern, sind kurz- und langfristig lokale Anstrengungen erforderlich, um die Krise in der Lake Tschad Region zu bewältigen. Kurzfristig wird die Verbesserung der humanitären Hilfe für Binnenvertriebene und ihre Ausweitung auf ärmere Haushalte in den Gastgemeinden nicht nur den Druck auf die Ressourcen in den Gastgemeinden verringern, sondern auch das Potenzial von Spannungen zwischen Binnenvertriebenen und Mitgliedern der Gastgemeinden reduzieren. Langfristig wird die Schaffung zusätzlicher Einkommensmöglichkeiten durch die Industrialisierung der Region die chronische Armut verringern, die viele junge Menschen dazu treibt, sich bewaffneten Gruppen anzuschließen. Der Schutz der Wasserressourcen durch den Bau von Bohrlöchern und die Regulierung von Bewässerungsaktivitäten wird eine nachhaltige Wassernutzung sicherstellen und die Ernährungssicherheit in der Region erhöhen.
This report was developed for the Leslie Harris Centre of Regional Policy and Development at Memorial University to assess the impacts of the Centre's Applied Research Fund (ARF). The evaluation focused on the first three rounds of ARF funding (2005/06, 2006/07 and 2007/08), as 2008/09 projects have not yet been completed, however the latest round of projects are discussed in this report where appropriate. The evaluation was conducted by assessing ARF's impacts through the lens of the Harris Centre Evaluation Framework. Findings were drawn from Harris Centre documents and ARF reports as well as from interviews and discussions with Harris Centre staff, ARF researchers and relevant external stakeholders (i.e. community representatives, including government departments and agencies, community organizations, businesses and business organizations, and individuals). The Harris Centre has a mandate to coordinate and facilitate Memorial University's educational, research and outreach activities in the areas of regional policy and development. The Harris Centre created the Applied Research Fund to stimulate research activities relevant to Newfoundland and Labrador's regional policy and development needs and opportunities by offering funding up to $15,000 to Memorial faculty, students and staff to conduct such research. The Harris Centre also utilizes ARF to encourage researchers to mobilize the findings from their work to stakeholders in the community who can make use of them. ARF has received funding from the NL Department of Innovation, Trade and Rural Development (INTRD) and the Atlantic Canada Opportunities Agency (ACOA). In the first four rounds, funding to ARF totalled $100,000 each year. Consistent with the mandates of INTRD and ACOA, the Harris Centre places emphasis on providing ARF funding to projects that seek to contribute to economic and rural development in Newfoundland and Labrador's regions (see Appendix E for project descriptions). Since ARF's inception in 2005, 31 projects have been funded (21 in the first three years; see Appendix D for table of all projects). Two additional projects were awarded funding, but were cancelled due to extraneous circumstances; with permission from the funders, the Harris Centre reallocated these funds to further knowledge mobilization of other ARF projects (Appendix F). There were substantially more projects awarded to males and Memorial faculty than females and staff or students; the large majority of applications were from males and faculty members, which indicates that the Harris Centre should address the marketing of ARF so that it reaches and speaks to the other demographic groups. Gender parity was achieved in the latest round of funding (2008/09), so it appears that marketing has been corrected in this area. ARF funding is filling a valuable need by stimulating research that can assist external stakeholders in making policy and development decisions in Newfoundland and Labrador. ARF provides Memorial researchers with funding for projects that address Newfoundland and Labrador's regional policy and development issues, contributing to understandings of the province's unique context, needs and opportunities. Many projects funded through ARF would not likely have qualified for funding from other traditional academic sources, because other available sources are not likely to support: • NL-specific projects (which many other funders regard as only being of interest to a small readership), • the collection of base-line data (which is crucial in providing context for planning, but may not have direct or immediate impacts in itself), and/or • Research that crosses sectors (which is important for holistic approaches in policy and development). iv ARF also acts as a 'seed fund', in that once projects have received funding from ARF, researchers have been able to leverage much funding from other sources. The fifteen researchers interviewed were awarded a total of $202,950 through ARF. Three of these researchers reported that the funding they received directly led to leveraged funding of $5,215,000 plus in-kind funding, three researchers reported that ARF was helpful to them in obtaining more funding, one researcher reported that other sources took a greater interest in the project once ARF funding was received, and one researcher reported receiving $47,600 from other sources for a follow-up project (see 'Evidence of importance of funding to projects', Evaluation Question 3). The ARF projects funded between 2005/06 – 2007/08, provide context and understanding of Newfoundland and Labrador's unique history, needs and opportunities in regional policy and development. Some projects set out base-line data on which further inquiries can be addressed while other projects investigated assumptions, policies and practices relevant to management decisions. This evaluation categorizes the ARF projects by themes under Evaluation Question 2 and in Appendix E to identify the relevance of projects to Newfoundland and Labrador's regional policy and development issues. The six themes identified were among Newfoundland and Labrador's most pressing needs and opportunities: A) Fisheries B) Renewable energy C) Natural resources D) Economy E) Governance and Community Organization F) Culture Through ARF projects, Memorial researchers have developed expertise in applied regional policy and development research and in maximizing the impacts of their findings by transferring them to external stakeholders who can use them. External stakeholders have also developed expertise through the collaborations stimulated by ARF's emphasis on applied connections to community needs and opportunities. The expertise developed by researchers and external stakeholders were often viewed by interviewees as only incremental to their prior, substantial expertise. ARF had the most impact on developing expertise where researchers had little prior experience in applied research with community relevance and applicability. Overall, both researchers and external stakeholders gained appreciation for the potential for academic / community collaborations and felt optimistic about seeking out future opportunities for collaborations. Findings and reports from ARF projects have been widely communicated to external stakeholders through an array of means. ARF's requirement that applicants develop a Knowledge Mobilization Plan has encouraged researchers to think about how they can deliver their findings to maximize the likelihood of impact. The Harris Centre has provided many opportunities for researchers and external stakeholders to engage in two-way knowledge transfer, but should continue working to maximize dissemination opportunities as outlined in the current Request for Proposals (Appendix C). Directly connecting changes in policy and practices to a singular piece of research can be difficult. Before research is adopted and implemented by external stakeholders with capacity to affect change, there is often a substantial time lag in which knowledge is diffused and previous understandings and approaches in society must be shifted. Despite these difficulties, it is clear that the findings from many ARF projects are reaching external stakeholders who can make use of them – findings from many projects have been taken under advisement by external stakeholders and there is ongoing discussion between researchers and external stakeholders on several projects. Several ARF projects have substantial potential for affecting direct change, and are close to realizing their full impact in economic and regional policy and practices. Appendix E provides a summary of ARF projects (2005/06 – 2007/08) and their potential benefits and impacts. Some of the most notable of these are recapped below: • Dag Friis' design of a hull for a pleasure trawler boat will assist boat builders in Newfoundland & Labrador in adapting to changing market trends, while maintaining a 'home-grown' feel and developing v skills within the province. The Glovertown Shipyard is prepared to begin building the hull once it is ready. (2005/06 ARF project) • James Feehan's report on declining trends of federal government presence within the province (in both employment and decision-making capacity) has been relied on by NL stakeholders (including the provincial government and the City of St. John's) in applying pressure to the federal government to restore and improve levels of federal government presence. (2005/06 ARF project) • Tariq Iqbal designed hybrid energy systems for the northern and remote Labrador communities of Battle Harbour Island (2006/07 ARF project) and Port Hope Simpson and Cartwright (2007/08 ARF project), based on renewable resources available in each. The systems are being reviewed by stakeholders in the communities for feasibility. • Trevor Bell's workshop on the impacts of climate change on Labrador's renewable resources increased stakeholder (including government departments and local communities) understandings of the issues and their capacity to develop strategies for adaptation. (2007/08 ARF project) • Michael Wernerheim's report on the conditions in localities necessary to support industries can inform government on how to maximize the likelihood of economic success through strategic placement of industries within the province. (2005/06 ARF project) • Wade Locke's Atlantic Canadian contribution to the international study conducted by the Organization for Economic Co-operation and Development (OECD) on the role of higher education institutions in development brought together all four Atlantic provincial governments, the Atlantic associations of universities and of colleges, the Council of Atlantic Premiers and the Atlantic Provinces Economic Council. Locke's report inspired the Harris Centre to host an international conference on the role of Higher Education Institutions (Knowledge in Motion, Oct 16 – 18, 2008), attended by over 225 participants, from across Newfoundland and Labrador, every province in Canada, the United States, Iceland, Scotland, England, France, Denmark and Australia. (2005/06 ARF project)