Suchergebnisse

Am 27. August 1985 wurde nach knapp zweijähriger Herrschaft der selbst durch einen Putsch an die Macht gekommene Mohammed Buhari durch einen Staatsstreich des Generalstabschefs Ibrahim Babangida gestürzt. Das Hauptproblem der neuen nigerianischen Regierung ist es, eine konsensfähige wirtschaftspolitische Strategie zu finden, die vor allem die Auslandsverschuldung abbauen hilft. Generalmajor Babangida kam vermutlich einem Putsch jüngerer Offiziere zuvor, die mit der antidemokratischen und wirtschaftlich erfolglosen Politik Buharis unzufrieden waren. (SWP-Ort)

Analyse der Entwicklung der Nachrichtendienste in Nigeria. Die politisch strategische Bedeutung wird im Vergleich mit den US-Diensten FBI und CIA angesprochen. Erste systematische Ansätze gab es in Nigeria nach der Ermordung von Murtala Mohammed 1986 mit der Gründung der 'Nigerian Safety Organisation' (NSO). Unter der Regierung Buhari überzog die Organisation ihre Kompetenzen und wurde nach dem Sturz Buharis unter Babangida aufgelöst. Drei neue Organisationen wurden gebildet, das Personal qualifizierter ausgebildet, zudem auch das Polizeiwesen geändert und gesellschaftlichen Bedürfnissen angepaßt. (DÜI-Wsl)

This study is determined to compare the effect of integrated psychosocial stimulation, nutritional support, and water sanitation hygiene interventions on malnourished children. An individual randomized trial design comprising weekly home visits for 3 months in four locations of Kanam Local Government Area, Plateau state, was adopted. The eligible malnourished children were identified through a door–to–door survey using standard procedures of anthropometric measurements (weight, height, mid-upper arm circumference) and children with body mass index (BMI) < 16Kg/m2 were selected. A focus group discussion session, follow-up home visitation on weekly and monthly facilitation/support of mother-to-mother, weekly distribution of food supplements, home stimulation environment through the provision of WASH material and age-specific psychosocial stimulation activities were part of intervention strategies adopted for the study. The result shows a significant difference between base-line and end-line data, impacted by integrated package delivery which enhanced and improved nutritional and developmental outcomes of malnourished children over the period of intervention. Furthermore, the findings reveal that there is a non-significant difference among the study groups. However, the observed effect on outcomes based on average BMI indicators is at causal pathways to improve child nutritional status outcomes. The study concludes that the integrated intervention package improved the developmental and nutritional outcomes in malnourished children. Implementation of these integration packages over a longer duration is needed to witness a significant improvement.

AbstractUrothelial cell carcinoma (UCC) is the ninth most common cancer that accounts for 4.7% of all new cancer cases globally. UCC development and progression are due to complex and stochastic genetic programs. To study the cascades of molecular events underlying the poor prognosis that may lead to limited treatment options for advanced disease and resistance to conventional therapies in UCC, transcriptomics technology (RNA‐Seq), a method of analyzing the RNA content of a sample using modern high‐throughput sequencing platforms has been employed. Here, we review the principles of RNA‐Seq technology and summarize recent studies on human bladder cancer that employed this technique to unravel the pathogenesis of the disease, identify biomarkers, discover pathways and classify the disease state. We list the commonly used computational platforms and software that are publicly available for RNA‐Seq analysis. Moreover, we discussed the future perspectives for RNA‐Seq studies on bladder cancer and recommended the application of a new technology called single‐cell sequencing to further understand the disease.