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ENIGMA-CNV working group. ; Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers display a high prevalence of micro- and macrocephaly in deletion and duplication carriers, respectively. The underlying brain structural diversity remains largely unknown. We systematically called CNVs in 38 cohorts from the large-scale ENIGMA-CNV collaboration and the UK Biobank and identified 28 1q21.1 distal deletion and 22 duplication carriers and 37,088 non-carriers (48% male) derived from 15 distinct magnetic resonance imaging scanner sites. With standardized methods, we compared subcortical and cortical brain measures (all) and cognitive performance (UK Biobank only) between carrier groups also testing for mediation of brain structure on cognition. We identified positive dosage effects of copy number on intracranial volume (ICV) and total cortical surface area, with the largest effects in frontal and cingulate cortices, and negative dosage effects on caudate and hippocampal volumes. The carriers displayed distinct cognitive deficit profiles in cognitive tasks from the UK Biobank with intermediate decreases in duplication carriers and somewhat larger in deletion carriers—the latter potentially mediated by ICV or cortical surface area. These results shed light on pathobiological mechanisms of neurodevelopmental disorders, by demonstrating gene dose effect on specific brain structures and effect on cognitive function. ; 1000BRAINS: The 1000BRAINS study was funded by the Institute of Neuroscience and Medicine, Research Center Juelich, Germany. We thank the Heinz Nixdorf Foundation (Germany) for the generous support of the Heinz Nixdorf Recall Study on which 1000BRAINS is based. We also thank the scientists and the study staff of the Heinz Nixdorf Recall Study and 1000BRAINS. Funding was also granted by the Initiative and Networking Fund of the Helmholtz Association (Caspers) and the European Union's Horizon 2020 Research and Innovation Programme under Grant Agreement 945539 (Human Brain Project SGA3; Amunts, Caspers, Cichon). Brainscale: The Brainscale study was supported by the Netherlands Organization for Scientific Research MagW 480-04-004 (Dorret I. Boomsma), 51.02.060 (Hilleke E. Hulshoff Pol), 668.772 (Dorret I. Boomsma and Hilleke E. Hulshoff Pol); NWO/SPI 56-464-14192 (Dorret I. Boomsma), the European Research Council (ERC-230374) (Dorret I. Boomsma), High Potential Grant Utrecht University (Hilleke E.Hulshoff Pol) and NWO Brain and Cognition 433-09-220 (Hilleke E.Hulshoff Pol). Betula: The Betula study was funded by the Knut and Alice Wallenberg (KAW) foundation (Nyberg). The Freesurfer segmentations on the Betula sample were performed on resources provided by the Swedish National Infrastructure for Computing (SNIC) at HPC2N (in Umeå, Sweden), partially funded by the Swedish Research Council through grant agreement no. 2018-05973. Brain Imaging Genetics (BIG): This work makes use of the BIG database, first established in Nijmegen, The Netherlands, in 2007. This resource is now part of Cognomics (www.cognomics.nl), a joint initiative by researchers from the Donders Centre for Cognitive Neuroimaging, the Human Genetics and Cognitive Neuroscience departments of the Radboud University Medical Centre and the Max Planck Institute for Psycholinguistics in Nijmegen. The Cognomics Initiative has received support from the participating departments and centres and from external grants, that is, the Biobanking and Biomolecular Resources Research Infrastructure (Netherlands) (BBMRI-NL), the Hersenstichting Nederland and the Netherlands Organization for Scientific Research (NWO). The research leading to these results also receives funding from the NWO Gravitation grant 'Language in Interaction', the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement nos. 602450 (IMAGEMEND), 278948 (TACTICS) and 602805 (Aggressotype), as well as from the European Community's Horizon 2020 programme under grant agreement no. 643051 (MiND) and from ERC-2010-AdG 268800-NEUROSCHEMA. In addition, the work was supported by a grant for the ENIGMA Consortium (grant number U54 EB020403) from the BD2K Initiative of a cross-NIH partnership. deCODE genetics: deCODE genetics acknowledges support from the Innovative Medicines Initiative Joint Undertaking under grant agreement nos. 115008 (NEWMEDS) and 115300 (EUAIMS), of which resources are composed of EFPIA in-kind contribution and financial contribution from the European Union's Seventh Framework Programme (EU-FP7/2007-2013), EU-FP7-funded grant agreement no. 602450 (IMAGEMEND) and EU-funded FP7-People-2011-IAPP grant agreement no. 286213 (PsychDPC). Dublin: This work was supported by Science Foundation Ireland (SFI grant 12/IP/1359 to Gary Donohoe and grant SFI08/IN.1/B1916-Corvin to Aidan C. Corvin). ECHO-DEFINE: The ECHO study acknowledges funding from a Medical Research Council (MRC) Centre Grant to Michael J. Owen (G0801418), the Wellcome Trust (Institutional Strategic Support Fund (ISSF) to van den Bree and Clinical Research Training Fellowship to Joanne L. Doherty), the Waterloo Foundation (WF 918-1234 to van den Bree), the Baily Thomas Charitable Fund (2315/1 to van den Bree), National Institute of Mental Health (NIMH 5UO1MH101724 to van den Bree and Michael J. Owen), the IMAGINE-2 study (funded by the MRC (MR/T033045/1) to van den Bree, Jeremy Hall and Michael J. Owen), the IMAGINE-ID study (funded by MRC (MR/N022572/1) to Jeremy Hall, van den Bree and Owen). The DEFINE study was supported by a Wellcome Trust Strategic Award (100202/Z/12/Z) to Michael J. Owen. ENIGMA: ENIGMA is supported in part by NIH grants U54 EB20403, R01MH116147 and R56AG058854. NIA T32AG058507; NIH/NIMH 5T32MH073526. EPIGEN-Dublin: The EPIGEN-Dublin cohort was supported by a Science Foundation Ireland Research Frontiers Programme award (08/RFP/GEN1538). EPIGEN-UK (Sisodiya): The work was partly undertaken at UCLH/UCL, which received a proportion of funding from the UK Department of Health's NIHR Biomedical Research Centres funding scheme. We are grateful to the Wolfson Trust and the Epilepsy Society for supporting the Epilepsy Society MRI scanner. GAP: This work was supported by the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry, Psychology and Neuroscience, King's College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. GOBS: The GOBS study data collection was supported in part by the National Institutes of Health (NIH) grants: R01 MH078143, R01 MH078111 and R01 MH083824, with work conducted in part in facilities constructed under the support of NIH grant C06 RR020547. GSP: Data were in part provided by the Brain Genomics Superstruct Project (GSP) of Harvard University and Massachusetts General Hospital (MGH) (Principal Investigators: Randy Buckner, Jordan Smoller and Joshua Roffman), with support from the Center for Brain Science Neuroinformatics Research Group, Athinoula A. Martinos Center for Biomedical Imaging, Center for Genomic Medicine and Stanley Center for Psychiatric Research. Twenty individual investigators at Harvard and MGH generously contributed data to the overall project. We would like to thank Randy Buckner for insightful comments and feedback on this work. HUBIN: The HUBIN study was financed by the Swedish Research Council (K2010-62X-15078-07-2, K2012-61X-15078-09-3, 521-2014-3487 K2015-62X-15077-12-3, 2017-00949), the regional agreement on medical training and clinical research between Stockholm County Council and the Karolinska Institutet. HUNT: The HUNT study is a collaboration between HUNT Research Centre (Faculty of Medicine and Movement Sciences, NTNU—Norwegian University of Science and Technology), Nord-Trøndelag County Council, Central Norway Health Authority and the Norwegian Institute of Public Health. HUNT-MRI was funded by the Liaison Committee between the Central Norway Regional Health Authority and the Norwegian University of Science and Technology, and the Norwegian National Advisory Unit for functional MRI. IMAGEN: This work received support from the following sources: the European Union-funded FP6 Integrated Project IMAGEN (reinforcement-related behaviour in normal brain function and psychopathology) (LSHM-CT- 2007-037286), the Horizon 2020 funded ERC Advanced Grant 'STRATIFY' (Brain network based stratification of reinforcement-related disorders) (695313), ERANID (Understanding the Interplay between Cultural, Biological and Subjective Factors in Drug Use Pathways) (PR-ST-0416-10004), BRIDGET (JPND: BRain Imaging, cognition Dementia and next generation GEnomics) (MR/N027558/1), Human Brain Project (HBP SGA 2, 785907),the FP7 projects IMAGEMEND(602450; IMAging GEnetics for MENtal Disorders) and MATRICS (603016), the Innovative Medicine Initiative Project EUAIMS (115300-2), the Medical Research Council Grant 'c-VEDA' (Consortium on Vulnerability to Externalizing Disorders and Addictions) (MR/N000390/1), the Swedish Research Council FORMAS, the Medical Research Council, the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, the Bundesministeriumfür Bildung und Forschung (BMBF grants 01GS08152, 01EV0711; eMED SysAlc01ZX1311A; Forschungsnetz AERIAL 01EE1406A, 01EE1406B), the Deutsche Forschungsgemeinschaft (DFG grants, SM 80/7-2, SFB 940/2), the Medical Research Foundation and Medical Research Council (grants MR/R00465X/1 and MR/S020306/1). Further support was provided by grants from: ANR (project AF12-NEUR0008-01—WM2NA, ANR-12-SAMA-0004), the Eranet Neuron (ANR-18-NEUR00002-01), the Fondation de France (00081242), the Fondation pour la Recherche Médicale (DPA20140629802), the Mission Interministérielle de Lutte-contre-les-Drogues-et-les-Conduites-Addictives (MILDECA), the Assistance-Publique-Hôpitaux-de-Paris and INSERM (interface grant), Paris Sud University IDEX 2012, the Fondation de l'Avenir (grant AP-RM-17-013), the Fédération pour la Recherche sur le Cerveau; the National Institutes of Health, Science Foundation Ireland (16/ERCD/3797), USA (Axon, Testosterone and Mental Health during Adolescence; RO1 MH085772-01A1) and by NIH Consortium grant U54 EB020403, supported by a cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence. Lifespan: The study is funded by the Research Council of Norway (230345, 288083 and 223273). NCNG: NCNG sample collection was supported by grants from the Bergen Research Foundation and the University of Bergen, the Dr Einar Martens Fund, the Research Council of Norway, to le Hellard, Steen and Espeseth. The Bergen group was supported by grants from the Western Norway Regional Health Authority (Grant 911593 to Arvid Lundervold, Grant 911397 and 911687 to Astri Johansen Lundervold). NTR: The NTR cohort was supported by the Netherlands Organization for Scientific Research (NWO) and The Netherlands Organisation for Health Research and Development (ZonMW) grants 904-61-090, 985-10-002, 912-10-020, 904-61-193, 480-04-004,463-06-001, 451-04-034, 400-05-717, Addiction-31160008, 016-115-035, 481-08-011, 056-32-010, Middelgroot-911-09-032, OCW_NWO Gravity programme—024.001.003, NWO-Groot 480-15-001/674, Center for Medical Systems Biology (CSMB, NWO Genomics), NBIC/BioAssist/RK(2008.024), Biobanking and Biomolecular Resources Research Infrastructure (BBMRI-NL, 184.021.007 and 184.033.111); Spinozapremie (NWO-56-464-14192), KNAW Academy Professor Award (PAH/6635) and University Research Fellow grant (URF) to Dorret I. Boomsma; Amsterdam Public Health research institute (former EMGO+), Neuroscience Amsterdam research institute (former NCA); the European Science Foundation (ESF, EU/QLRT-2001-01254), the European Community's Seventh Framework Programme (FP7- HEALTH-F4-2007-2013, grant 01413: ENGAGE and grant 602768: ACTION); the European Research Council (ERC Starting 284167, ERC Consolidator 771057, ERC Advanced 230374), Rutgers University Cell and DNA Repository (NIMH U24 MH068457-06), the National Institutes of Health (NIH, R01D0042157-01A1, R01MH58799-03, MH081802, DA018673, R01 DK092127-04, Grand Opportunity grants 1RC2 MH089951 and 1RC2 MH089995); the Avera Institute for Human Genetics, Sioux Falls, South Dakota (USA). Part of the genotyping and analyses were funded by the Genetic Association Information Network (GAIN) of the Foundation for the National Institutes of Health. Computing was supported by NWO through grant 2018/EW/00408559, BiG Grid, the Dutch e-Science Grid and SURFSARA. OATS: The OATS study has been funded by a National Health & Medical Research Council (NHMRC) and Australian Research Council (ARC) Strategic Award Grant of the Ageing Well, Ageing Productively Programme (ID No. 401162) and NHMRC Project Grants (ID Nos. 1045325 and 1085606). This research was facilitated through Twins Research Australia, a national resource in part supported by an NHMRC Centre for Research Excellence Grant (ID No.: 1079102). We thank the participants for their time and generosity in contributing to this research. We acknowledge the contribution of the OATS research team (https://cheba.unsw.edu.au/project/older-australian-twins-study) to this study. OATS genotyping was partly funded by a Commonwealth Scientific and Industrial Research Organization Flagship Collaboration Fund Grant. Osaka: Osaka study was supported by the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS: Grant Number JP18dm0207006), Brain/MINDS& beyond studies (Grant Number JP20dm0307002) and Health and Labour Sciences Research Grants for Comprehensive Research on Persons with Disabilities (Grant Number JP20dk0307081) from the Japan Agency for Medical Research and Development (AMED), Grants-in-Aid for Scientific Research (KAKENHI; Grant Numbers JP25293250 and JP16H05375). Some computations were performed at the Research Center for Computational Science, Okazaki, Japan. PAFIP: The PAFIP study was supported by Instituto de Salud Carlos III, FIS 00/3095, 01/3129, PI020499, PI060507, PI10/00183, the SENY Fundació Research Grant CI2005-0308007 and the FundaciónMarqués de Valdecilla API07/011. Biological samples from our cohort were stored at the Valdecilla Biobank and genotyping services were conducted at the Spanish 'Centro Nacional de Genotipado' (CEGEN-ISCIII). MCIC/COBRE: The study is funded by the National Institutes of Health studies R01EB006841, P20GM103472 and P30GM122734 and Department of Energy DE-FG02-99ER62764. PING: Data collection and sharing for the Paediatric Imaging, Neurocognition and Genetics (PING) Study (National Institutes of Health Grant RC2DA029475) were funded by the National Institute on Drug Abuse and the Eunice Kennedy Shriver National Institute of Child Health & Human Development. A full list of PING investigators is at http://pingstudy.ucsd.edu/investigators.html. QTIM: The QTIM study was supported by the National Institute of Child Health and Human Development (R01 HD050735) and the National Health and Medical Research Council (NHMRC 486682, 1009064), Australia. Genotyping was supported by NHMRC (389875). Medland is supported in part by an NHMRC fellowship (APP1103623). SHIP: SHIP is part of the Community Medicine Research net of the University of Greifswald, Germany, which is funded by the Federal Ministry of Education and Research (grant nos. 01ZZ9603, 01ZZ0103 and 01ZZ0403), the Ministry of Cultural Affairs and the Social Ministry of the Federal State of Mecklenburg-West Pomerania. Genome-wide single-nucleotide polymorphism typing in SHIP and MRI scans in SHIP and SHIP-TREND have been supported by a joint grant from Siemens Healthineers, Erlangen, Germany and the Federal State of Mecklenburg-West Pomerania. StrokeMRI: StrokeMRI was supported by the Norwegian ExtraFoundation for Health and Rehabilitation(2015/FO5146), the Research Council of Norway (249795, 262372), the South-Eastern Norway Regional Health Authority (2014097, 2015044, 2015073) and the Department of Psychology, University of Oslo. Sydney MAS: The Sydney Memory and Aging Study (Sydney MAS) is funded by National and HealthMedical Research Council (NHMRC) Programme and Project Grants (ID350833, ID568969 and ID109308). We also thank the Sydney MAS participants and the Research Team. SYS: The SYS Study is supported by Canadian Institutes of Health Research. TOP: Centre of Excellence: RCN #23273 and RCN #226971. Part of this work was performed on the TSD (Tjeneste for Sensitive Data) facilities, owned by the University of Oslo, operated and developed by the TSD service group at the University of Oslo, IT-Department (USIT) (tsd-drift@usit.uio.no). The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7-PEOPLE-2013-COFUND) under grant agreement no. 609020—Scientia Fellows; the Research Council of Norway (RCN) #276082—A lifespan perspective on mental illness: toward precision medicine using multimodal brain imaging and genetics. Ida E. Sønderby and Rune Bøen are supported by South-Eastern Norway Regional Health Authority (#2020060). Ida E. Sønderby and Ole A. Andreassen have received funding from the European Union's Horizon 2020 Research and Innovation Programme under Grant agreement no. 847776 (CoMorMent project) and the KG Jebsen Foundation (SKGJ-MED-021). UCLA_UMCU: The UCLA_UMCU cohort comprises of six studies which were supported by National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD) (20244 to Prof. Hillegers), The Netherlands Organisation for Health Research and Development (ZonMw) (908-02-123 to Prof. Hulshoff Pol), and Netherlands Organisation for Scientific Research (NWO 9120818 and NWO-VIDI 917-46-370 to Prof. Hulshoff Pol). The GROUP study was funded through the Geestkracht programme of the Dutch Health Research Council (ZonMw, grant number 10-000-1001), and matching funds from participating pharmaceutical companies (Lundbeck, AstraZeneca, Eli Lilly and Janssen Cilag) and universities and mental health care organizations (Amsterdam: Academic Psychiatric Centre of the Academic Medical Center and the mental health institutions: GGZ inGeest, Arkin, Dijk en Duin, GGZ Rivierduinen, Erasmus Medical Centre, GGZ Noord-Holland-Noord. Groningen: University Medical Center Groningen and the mental health institutions: Lentis, GGZ Friesland, GGZ Drenthe, Dimence, Mediant, GGNet Warnsveld, Yulius Dordrecht and Parnassia Psycho-medical Center, The Hague. Maastricht: Maastricht University Medical Centre and the mental health institutions: GGzE, GGZ Breburg, GGZ Oost-Brabant, Vincent van Gogh, voor Geestelijke Gezondheid, Mondriaan, Virenzeriagg, Zuyderland GGZ, MET ggz, Universitair Centrum Sint-JozefKortenberg, CAPRI University of Antwerp, PC Ziekeren Sint-Truiden, PZ Sancta Maria Sint-Truiden, GGZ Overpelt, OPZ Rekem. Utrecht: University Medical Center Utrecht and the mental health institutions: Altrecht, GGZ Centraal and Delta.). UK Biobank: This work made use of data sharing from UK Biobank (under project code 27412). Others: Work by Pierre Vanderhaeghen was funded by Grants of the European Research Council (ERC Adv Grant GENDEVOCORTEX), the EOS Programme, the Belgian FWO, the AXA Research Fund and the Belgian Queen Elizabeth Foundation. Ikuo K. Suzuki was supported by a postdoctoral fellowship of the FRS/FNRS. ; Peer reviewed

In einer Welt, die sich zunehmend der Wichtigkeit des Umweltschutzes bewusst wird, ist es an der Zeit, über ein Thema zu sprechen, das nicht nur unsere Ökosysteme betrifft, sondern auch tiefergreifende soziale Ungerechtigkeiten aufdeckt. Wir sind alle Zeugen und Verursacher des Klimawandels und seiner verheerenden Auswirkungen. Nun wollen wir genauer hinsehen und verstehen, wie dieser Wandel bestimmte Gemeinschaften in unverhältnismäßigem Maß betrifft. Die Rede ist von Umweltrassismus.Im Folgenden soll gezeigt werden, dass Umweltprobleme nicht gleichmäßig auf alle Bevölkerungsgruppen verteilt sind, sondern oft die treffen, die bereits benachteiligt sind. Dafür wird zuerst der Begriff Umweltrassismus aus verschiedenen Perspektiven betrachtet. Anschließend wird an Beispielen genauer aufgezeigt, was für Arten es gibt, bevor es um Lösungsvorschläge gehen wird.In dem Beitrag wird von BIPoC gesprochen. BIPoC steht für "Black, Indigenous and People of Colour". Das Akronym setzt sich also aus politischen Selbstbezeichnungen von Menschen zusammen, die von rassistischer Unterdrückung betroffen sind.Ursprung des Begriffs "Umweltrassismus"?Dass die Folgen des Klimawandels immer verheerender werden, ist nichts Neues. Und dass dies enorme Gesundheitsfolgen mit sich bringt, ist auch bekannt. Dabei wird zwischen direkten (primären) Folgen und indirekten (sekundären und tertiären) Folgen unterschieden. Zu den direkten Folgen zählen eine erhöhte Sterbe- und Erkrankungsrate durch Ereignisse wie Hitzewellen, Überschwemmungen oder Waldbränden. Zu den indirekten Folgen gehören Auswirkungen wie Nahrungsmittelknappheit, Zunahme von Infektionskrankheiten und Allergien. Außerdem gibt es sozial bedingte Folgen, beispielsweise Hungersnöte, Entwicklungsstagnation oder Kriege (Kuehni, Egger 2012, S. 190). Doch was ist, wenn Teile der Erde oder bestimmte Gruppen schlimmer unter den Folgen des Klimawandels leiden als andere? In diesem Zusammenhang wird mittlerweile immer häufiger von "Umweltrassismus" gesprochen.Der Begriff kam Anfang der 1980er Jahre auf. Damals suchte der Bundesstaat North Carolina einen Ort, an dem man mit Polychlorierte Biphenylen (PCB) verseuchte Erde entsorgen kann. Zuerst war eine Entsorgungsdeponie in einem Bezirk mit hauptsächlich weißen Menschen geplant. Eine Bürgerinitiative verhinderte dies. Daraufhin war schnell klar, dass die Deponie in einem der Bezirke mit hauptsächlich schwarzen, armen oder anderweitig benachteiligten Nachbarschaften errichtet werden sollte.1982 wurde beschlossen, die verseuchte Erde in einer kleinen Gemeinde namens Afton zu entsorgen. Diese Stadt liegt in Warren County, dem damals ärmsten Landkreis in North Carolina mit einem schwarzen Bevölkerungsanteil von 65 %. Die Bevölkerung versuchte dagegen anzugehen. Zuerst gerichtlich, doch als das nichts half, gab es über sechs Wochen Sitzblockaden, Straßensperren und Demonstrationen. Dabei wurden mehr als 500 Demonstrierende verhaftet. Doch alle Bemühungen halfen nichts. Die Mülldeponie wurde dennoch gebaut. (Ituen/Tatu Hey 2021, S. 4-5). Kurz darauf wurde PCB weltweit verboten, da es sich als hochgiftig, krebserregend und erbgutschädigend herausstellte (Warda 2020).Trotz der Niederlage bei dem Bau der Deponie waren diese Proteste von großer Bedeutung und wurden von vielen anderen als Vorbild genommen. Aus Kämpfen gegen diese Art von Umweltrassismus ist schließlich die Bewegung für Klimagerechtigkeit hervorgegangen, welche erstmals Fragen sozialer Gerechtigkeit im Zusammenhang mit umweltpolitischen Aspekten betrachtete (FARN, o.J.). Geprägt wurde der Begriff Umweltrassismus von dem Bürgerrechtler Dr. Benjamin F. Chavis Jr., der an den Demonstrationen in Afton beteiligt war. Er definiert Umweltrassismus als"the intentional siting of polluting and waste facilities in communities primarily populated by African Americans, Latines, Indigenous People, Asian Americans and Pacific Islanders, migrant farmworkers, and low-income workers" (Ihejirika 2023)Chavis veröffentlichte im Jahr 1987 gemeinsam mit der United Church of Christ (UCC) Kommission eine Studie zum Thema "Toxic Wastes and Race in the United States". Aus der Studie ging hervor, dass drei von fünf BIPoC nahe einer Giftmülldeponie wohnen. In einem Dokumentarfilm sagte Davis:"The issue of environmental racism is an issue of life and death. It is just not an issue of some form of prejudice where someone doesn't like you because of the color of your skin. This is an issue that will take your life away, if you don't get involved." (United Church of Christ 2023 / o.J.).Die Protestaktion und der Film löste eine nationale Debatte über Umweltrassismus aus (United Church of Christ 2023). Die Studie von 1987 wurde bis 2007 fortgesetzt und zeigte, dass nach wie vor eine Ungleichheit herrscht und Menschen aufgrund ihrer Hautfarbe einem höheren Risiko von umweltschädlichen Stoffen ausgesetzt sind. Noch immer werden Mülldeponien eher an Standorten mit einem hohen Anteil an BIPoC erbaut, als dort, wo weiße Menschen leben (Bullard et. al. 2007, S. 155).Seither gibt es immer mehr Studien zu Umweltrassismus. Diese bestätigen, dass PoC viel stärker Umweltrisiken ausgesetzt sind als weiße Personen. Die Ursache liegt vor allem darin, dass die Industrie sich meistens dort ansiedelt, wo hauptsächlich BIPoC leben. Deshalb sind schwarze Menschen 1.5 Mal, Hispanics 1.2 Mal und einkommensschwache Menschen 1.3 Mal so viel Feinstaub ausgesetzt wie weiße Menschen bzw. einkommensstarke (Warda 2020). Durch die Studien und Veröffentlichungen zum Thema Umweltrassismus hat sich der Begriff weiterentwickelt. Der amerikanische Soziologe Robert Bullard definiert ihn als"any policy, practice or directive that differentially affects or disadvantages (where intended oder unintended) individuals, groups or communities based on race or color" (Batiste 2022, S. 1).Das Projekt "ENRICH" (Environmental Noxiousness, Racial Inequities, and Community Health) unterscheidet zwei Bestandteile des Umweltrassismus. Zum einen gibt es die räumliche Verteilungsungerechtigkeit, die sich auf die Standortwahl industrieller Umweltverschmutzer und anderer umweltgefährdender Projekte bezieht. Zum anderen handelt es sich um die Verfahrensungerechtigkeit. Dabei stehen die institutionellen Mechanismen und Richtlinien im Mittelpunkt, welche die Ungerechtigkeit aufrechterhalten (ENRICH o.J.).Umweltrassismus, Klimawandel und Kolonialismus Durch den Klimawandel werden weitere, ganz neue Seiten von Umweltrassismus aufgezeigt. Die Ursachen und Folgen des Klimawandels sind ungleich über den Planeten verteilt. Länder im globalen Süden sind meist viel stärker von den Auswirkungen des Klimawandels betroffen. Und das, obwohl sie deutlich weniger CO2-Emissionen erzeugen als der globale Norden (Warda 2020). Das zeigt, dass die Klimakrise die (globale) soziale Krise und somit den Umweltrassismus in großen Dimensionen enorm beeinflusst. Um dieses Ungleichgewicht von Nord- und Südkugel, welches mit dem Klimawandel einhergeht, zu erfassen, muss der Kolonialismus berücksichtigt werden.Im Zuge der Kolonialisierung kam es zu neuartigen globalen Handels- und Machtbeziehungen, welche bis heute anhalten. Dadurch blühte der globale Norden auf und erreichte Reichtum und Wohlstand (Bendix 2015, S. 273). Die Länder des globalen Südens galten als "Ressourcen- und Absatzmärkte" und halfen den Ländern auf der Nordhalbkugel, ihren Reichtum zu vermehren (Öztürk 2012, S. 2).Viele westliche Firmen wollen günstig in ärmeren Ländern produzieren. Meist haben die ärmeren Länder zudem eine fragile staatliche Struktur. Westliche Länder und Firmen nutzen dies aus und verschmutzen dadurch dort vor Ort die Natur und achten wenig auf Einheimische (Warda 2020). Der globale Süden wird ausgebeutet und leidet unter den massiven Eingriffen in deren Ökosysteme von außerhalb (Ziai 2012, S. 23).Aktuell zeigt sich eine erhebliche Diskrepanz im durchschnittlichen Pro-Kopf-Ausstoß von Emissionen zwischen den ärmsten Ländern, zu welchen Niger, Somalia und die Zentralafrikanische Republik gehören. Dieser Ausstoß ist in den ärmsten Ländern mehr als 140 Mal niedriger als beispielsweise in Deutschland. Dazu kommt die historische Verantwortung des Globalen Nordens hinsichtlich des Klimawandels. Der größte Teil der Emissionen, der sich seit Beginn der Industrialisierung in der Atmosphäre gesammelt hat, geht auf den Globalen Norden zurück (Kurwan 2023).Eine interessante Abbildung zu den Pro-Kopf-CO2-Emissionen im Jahr 2021 findet ihr hier. Dort wird der durchschnittliche Verbrauch von fast jedem Land dargestellt. Durch Klicken auf das Land kann man sehen, dass zum Beispiel Deutschland einen durchschnittlichen Pro-Kopf-Verbrauch an Emissionen von 8.09 hatte. Eine klare Nord-Süd Trennung der Welt ist erkennbar.Damals wie auch heute sind die Länder im globalen Süden zudem stark von der Landwirtschaft abhängig. Ihre Existenz steht babei auf dem Spiel. Um sich vor den Auswirkungen zu schützen, fehlt den Menschen, aber auch den Ländern, oftmals das Geld. Von außerhalb kommt wenig Hilfe und das, obwohl der Klimawandel ein globales Problem ist. Dennoch gibt es auf politischer Ebene einen einseitigen Fokus, welcher nur auf den vergleichsweise geringen Auswirkungen auf den globalen Norden liegt. Die Länder des globalen Südens werden mit den schlimmen gesellschaftlichen und ökologischen Folgeschäden nahezu allein gelassen.Das bedeutet nicht, dass einzelne Personen, welche die Entscheidungen treffen, eine konkrete diskriminierende Absicht haben (Bellina 2022, S. 64), aber dass viele die globalen Konsequenzen außen vor lassen und nicht bedenken. Die Folge? Sie müssen fliehen. Menschen können aufgrund der Probleme, die durch den Klimawandel ausgelöst werden, nicht in ihrer Heimat bleiben (Warda 2020).Laut einem Bericht des Internal Displacement Monitoring Centre (iDMC) aus dem Jahr 2015 verlassen seit 2008 jedes Jahr durchschnittlich 26.4 Mio. Menschen, ihre Heimat aufgrund von Naturkatastrophen. Das ist eine Person pro Sekunde. Die Zahl der geflohenen Personen sollen sich in den nächsten Jahren vervielfachen. Hauptursachen hierbei sind wetterbedingte Katastrophen wie Stürme, Überschwemmungen und Sturmfluten. Zu eher schleichenden Umweltproblemen wie Dürren oder dem ansteigenden Meeresspiegel gibt es (noch) keine konkreten Zahlen. Das sind deutlich mehr Personen, die aufgrund von Naturkatastrophen fliehen müssen, als aufgrund von Krieg. Oft stehen Umweltkatastrophen mit anderen Konflikten im Zusammenhang, beispielsweise Wasserknappheit (Yonetani 2015, S. 8). Umweltrassismus beeinflusst also das reale Überleben dieser Menschen.Doch nicht nur zwischen Süd und Nord gibt es Unterschiede. Auch die Einkommensunterschiede innerhalb eines Landes tragen dazu bei. So treffen die Folgen des Klimawandels die Menschen mit weniger Einkommen oft härter. Zum einen, weil sie weniger Wohnraum und somit weniger Rückzugsorte haben, zum anderen haben Einkommensschwache meist auch kein Auto oder eine andere Möglichkeit, am Straßenverkehr teilzunehmen und vor der Katastrophe zu fliehen (Adick 2022).Es kann auch Diskriminierung zwischen Geschlechtern und Generationen geben. Besonders Frauen und Kinder sind von den Folgen der Klimakrise betroffen (Kurwan 2023). Und das, obwohl Männer durchschnittlich mehr zur Klimaerwärmung beitragen als Frauen. Ein Grund dafür ist, dass Warnungen bei Naturkatastrophen größtenteils im öffentlichen Raum stattfinden, Frauen sich allerdings eher zuhause aufhalten und sich dort um Kinder und Haushalt kümmern und darum erst später davon erfahren. Sie sind auch bei der Flucht für Kinder und die Pflege der älteren Angehörigen zuständig (DGVN 2016). Ein weiterer Grund ist gerade bei Flutereignissen, dass Frauen seltener schwimmen können und schlechteren Zugang zu Verkehrsmitteln haben (Kurwan 2023).Eine Folge von Umweltkatastrophen, die nichts direkt mit Umweltrassismus zu tun hat, möchte ich dennoch nicht unerwähnt lassen. Laut Studien steigt die Anzahl der gewaltsamen Übergriffe auf Frauen nach Umweltkatastrophen enorm. Oftmals verdoppeln sich die Zahl der Gewalttaten von Männern gegenüber Frauen. Warum das konkret nach Katastrophen häufiger auftritt, hängt wahrscheinlich mit den fehlenden Strukturen im Chaos zusammen. Frauen sind dadurch weniger geschützt (DGVN 2016).Umweltrassismus kann also gegen einzelne Personen, Gruppen oder auch Länder auftreten. Aus den Kämpfen gegen Umweltrassismus erfolgten verschiedene Bewegungen für Klimagerechtigkeit. Einige sind uns allen bekannt, wie "Fridays for Future". Sie setzen sich nicht nur für Klimapolitik und Klimaschutz ein, sondern auch für Klimagerechtigkeit, wodurch dem Umweltrassismus entgegengewirkt werden soll (Fridays for Future 2020). Es handelt sich dabei also nicht nur um eine Klimabewegung, sondern um eine Klimagerechtigkeitsbewegung.FallbeispieleUm noch deutlicher zu zeigen, was für Arten von Umweltrassismus es auf der Erde gibt und wie oft diese auftreten, werden im Folgenden einige Beispiele aufgeführt.Das erste Beispiel handelt von den USA, genauer gesagt von den Gemeinden eines über 130 km langen Landstrichs entlang des Mississippi von Baton Rounge bis New Orleans in Louisiana. Hier haben sich insgesamt über 150 Ölraffinerien, Kunststofffabriken und andere chemische Anlagen angesiedelt, die viele Emissionen ausstoßen. Und das direkt an den zuvor bestehenden Siedlungen. Gleichzeitig weist der Abschnitt eine sehr hohe Inzidenz- und Sterblichkeitsrate im Vergleich zum Rest der USA auf. Auch die Krebsrate ist viel höher als im Rest des Landes. Aufgrund dessen wird dieser Abschnitt auch "Cancer Alley", die Allee der Krebskranken, genannt. In kaum einem anderen Bundesstaat ist die Luft so schlecht wie in Louisiana (Batiste 2022, S. 1).Doch nicht alle Menschen am Mississippi sind gleichermaßen betroffen. Vor allem die hier lebenden schwarzen Menschen auf der einen Seite des Flusses kämpfen gegen den Krebs. Verantwortlich dafür wird die Industrie gemacht. Auf der anderen Seite des Flusses leben hauptsächlich weiße Menschen, oftmals derselben Gemeinde. Aufgrund von Protesten wurden dort keine Industrieanlagen erbaut. Diese sehen die Industrie mittlerweile als Chance für neue Arbeitsplätze und Steuereinnahmen. Aber nur, wenn sie in einem bestimmten Abstand erbaut werden. Studien haben gezeigt: Je näher die Menschen an den Industrieanlagen wohnen, desto höher das Gesundheitsrisiko. Und da sich die Industrie hier auffällig nahe in Nachbarschaften mit hauptsächlich BIPoC oder Armen angesiedelt haben, gehen diese von einem rassistischen Motiv aus. Sie haben das Gefühl, geopfert zu werden, an zweiter Wahl zu stehen (Schmidt 2023).Eine Studie aus den USA zeigt, dass es eine besonders hohe Sterberate bei BIPoC gibt im Zusammenhang mit Hitzewellen. Vor allem in Großstädten sterben doppelt so viele wie weiße Menschen. Das liegt an den Temperaturdifferenzen innerhalb der schwarzen und weißen Nachbarschaft, welche bei bis zu 1.7° Celsius liegen kann (Ituen/Tatu Hey 2021, S. 12/13).Doch Umweltrassismus gibt es auch in Deutschland. So wurde durch verschiedene Studien festgestellt, dass es beispielsweise in Kassel eine erhöhte Luftverschmutzung in den Bezirken gibt, in welchen Menschen mit niedrigen sozioökonomischen Status und Migrationshintergrund wohnen (Ituen/Tatu Hey 2021, S. 9). Auch andere marginalisierte Gruppen, wie Sinti*zza und Rom*nja erleben dies immer wieder. Meistens werden sie in Gegenden mit einer hohen Umweltbelastung geschoben und von Umweltgütern wie sauberem Trinkwasser ausgeschlossen (Ituen/Tatu Hey 2021, S. 8).Eine neue Studie aus Chicago verdeutlicht, dass Schwarze während der Pandemie für 50 % der Corona-Infektionen und sogar 70 % der Todesfälle verantwortlich waren. Und das, obwohl sie lediglich 30 % der Bevölkerung von Chicago ausmachen. Und auch in Großbritannien zeigt sich, dass schwarze Menschen fast doppelt so häufig wie weiße Menschen einem erhöhten Risiko ausgesetzt sind, an Covid-19 zu sterben (Ituen/Tatu Hey 2021, S. 13).Ebenso können ganze Länder von Umweltrassismus betroffen sein, wie beispielsweise Senegal. Der globale Süden ist durch Kolonialisierung und jahrhundertelange Ausbeutung viel später in die Industrialisierung eingestiegen. Bis dahin haben die Länder des Nordens schon viel, viel mehr CO2 ausgestoßen, welches über 100 Jahre in der Atmosphäre bleibt. Trotzdem sollen die Länder des globalen Südens genau so viel CO2 einsparen wie die Länder auf der Nordhalbkugel. Gleichzeitig sollen sie die Schulden gegenüber dem globalen Norden abbauen. Das führt dazu, dass Länder im Süden (z.B. Senegal) ihre fossilen Energieträger von Industrienationen ausbeuten lassen, um nicht noch tiefer in die Schulden zu stürzen (Adick 2022).Umweltrassismus bekämpfenDie Bekämpfung von Umweltrassismus wird von Land zu Land unterschiedlich gehandhabt. Der gemeinsame Kern ist jedoch, dass das Leid der betroffenen Personen gemindert werden soll. Diese wollen auf sich aufmerksam machen und gegen das Unrecht ankämpfen. So war es auch bei Cancer Alley. Gemeinsam mit Anwälten wurden Klagen gegen staatliche Einrichtungen oder chemische Fabriken angestrengt (Schmidt 2023). Robert Taylor, der Gründer der Initiative gegen die Chemiefabriken, kämpft für eine bessere Zukunft. Vor allem für die BIPoC-Kinder der Gemeinden. Weitere Forderungen sind Verschärfungen von Vorschriften der EPA (Envioronmental Protection Agency), welche eine unabhängige Behörde der USA ist und sich für den Umweltschutz und den Schutz der menschlichen Gesundheit einsetzt, und eine Wiedergutmachung für die betroffenen und hinterbliebenen Personen (Batiste 2022, S. 29).Mittlerweile hat auch Präsident Joe Biden davon gehört und Taylor ins Weiße Haus eingeladen. Hier soll er verdeutlichen, dass Umweltschutz oberste Priorität hat und somit auch dem Umweltrassismus entgegengewirkt werden kann. Es gibt den Anwohner*innen und Umweltgruppen Hoffnung. Außerdem verlangen sie mehr Forschung zu dem Thema, um besser ihr Leid belegen zu können. Sie glauben, dass die Politik ihnen dann mehr Glauben schenkt (Schmidt 2023). Die daraus resultierende nationale Aufmerksamkeit soll der Wendepunkt von Cancer Alley sein (Batiste 2022, S. 29).Ein weiteres einzigartiges und innovatives Projekt wurde 2012 von Dr. Ingrid Waldron in Kanada ins Leben gerufen. Dabei handelt es sich um das sogenannte ENRICH-Projekt (Environmental Noxiousness, Racial Inequities, and Community Health), welches sich auf die sozialen, ökologischen, politischen und gesundheitlichen Auswirkungen von Umweltrassismus in Mi´kmaq-Gemeinden (Ureinwohner*innen) und Nova Scotia, einer kleinen Provinz in Kanada, spezialisieret (ENRICH o.J.). Die hauptsächlich dort lebenden BIPoC berichten von Krankheiten wie Krebs oder Diabetes, welche aufgrund von Mülldeponien, die 1974 und 2006 eröffnet wurden, hervorgerufen wurden. Außerdem hatten sie kaum Zugang zu sauberem Trinkwasser, da das Wasser viele Giftstoffe enthielt. Der Müll zog zudem Bären, Waschbären und Insekten an (Klingbeil 2016).Das Projekt will Wege finden, um räumliche wie verteilungstechnische Arten des Umweltrassismus in diesen Gemeinden anzugehen und mithilfe der Bürger*innen die Politik bzw. Politiker*innen zum Handeln zu zwingen. Des Weiteren wollen sie national über die Ansiedlung und Regulierung von Industrieanlagen im Zusammenhang mit Umweltrassismus informieren. Das machen sie mithilfe von Interessenvertretungen, gemeinschaftlichem Engagement, Mobilisierung und Kapazitätsaufbau in betroffenen Gemeinden, öffentlicher Bildung, Studierendenausbildung, sektorübergreifenden Partnerschaften, Workshops und Kommunikation (ENRICH o.J.). Auch ihnen ist es in erster Linie wichtig, auf diese Umstände aufmerksam zu machen. Die Beteiligten schafften es, dass im Jahr 2015 zum ersten mal in Kanada ein Gesetzesentwurf zum Thema Umweltrassismus eingebracht und bis zur zweiten Lesung durchgebracht wurde. Allerdings wurde das Gesetz nicht verabschiedet (Klingbeil 2016).Das Projekt sorgte weltweit für Aufsehen. Im April 2018 veröffentlichte Waldron das Buch "There´s something in the water" und verwendete Nova Scotia als Fallbeispiel, um die Auswirkungen von Umweltrassismus und dessen gesundheitliche Folgen auf indigene und schwarze Gemeinschaften in Kanada zu untersuchen. Das Buch erhielt zwei Preise. 2019 wurde der gleichnamige Dokumentarfilm veröffentlicht.Das sind einzelne Projekte, die wichtig sind und von denen Betroffene profitieren können. Jedoch können sie nicht dem globalen Umweltrassismus entgegenwirken, welcher heute enorme Dimensionen angenommen hat. Nicht nur Bevölkerungsgruppen, sondern auch Länder sind unterschiedlich von den Folgen des Klimawandels betroffen. Die Politik kann und muss dagegen ankämpfen. Es gibt schon Lösungsideen, wie dem Umweltrassismus entgegengewirkt werden kann.Ein Prinzip, das dabei beachtet werden sollte, ist das Verursacherprinzip. Dabei sollen nicht nur die aktuellen Emissionen berücksichtigt werden, sondern auch die historische Verantwortung. Das bedeutet, dass beachtet werden muss, welches Land wie viel CO2 in der Vergangenheit ausgestoßen hat. Dadurch verändert sich das CO2-Budget der Länder im Norden. Teilweise wäre das Budget schon komplett aufgebraucht. Außerdem sollen die Nationen des globalen Nordens die Verantwortung als hauptsächliche Verursacher des Klimawandels auf sich nehmen und für die Kosten von Anpassungsstrategien und klimabedingten Schäden in Ländern des globalen Südens aufkommen müssen (Kurwan 2023).Eine weitere Lösung, die das Problem beheben könnte, ist ein Schuldenerlass. Das führt dazu, dass fossile Energieträger des globalen Südes im Boden bleiben können und die Länder das Geld anders investieren können. Beispielsweise in eine Veränderung, die sozial und ökologisch gerecht wäre. Des Weiteren könnten sie mit dem Geld die Klimaanpassung (mit-)finanzieren. Viele Wissenschaftler*innen oder auch der Internationale Währungsfonds (IWF) haben sich positiv zu dieser Lösung geäußert. Somit könnte den ärmeren Ländern mehr finanzieller Spielraum gegeben werden. Das kann ein Hilfsmittel gegen die Ungerechtigkeit sein. Jedoch kann es diese nicht komplett lindern. Der Norden muss definitiv noch mehr investieren. Denn wie schon weiter oben gesagt, hängt die Klimakrise eng mit der sozialen Gerechtigkeit und somit dem Umweltrassismus zusammen.FazitDer Beitrag beleuchtete das komplexe Thema des Umweltrassismus. Der Begriff wurde Anfang der 1980er Jahre geprägt und bekommt immer mehr Bedeutung. Umweltrassismus hat viele Facetten. Es tritt auf, wenn Umweltprobleme und Umweltverschmutzung unverhältnismäßig stark bestimmte Gemeinschaften betreffen. Meist betrifft es die Menschen, die bereits benachteiligt sind.Umweltrassismus ist also nicht nur eine Frage der Umwelt, sondern auch eine der sozialen Gerechtigkeit, wenn nicht sogar eine Frage von Leben und Tod. Neben BIPoC können auch Geschlechter und Generationen sowie ganze Länder direkt oder indirekt betroffen sein. Häufig trifft es Frauen, Kinder und Einkommensschwache am stärksten.Der globale Norden, der historisch für einen Großteil der CO2-Emissionen verantwortlich ist, leidet weniger unter den Folgen des Klimawandels als der globale Süden. Und das, obwohl der Süden deutlich weniger Emissionen verursacht.Um dem Umweltrassismus entgegenzuwirken, gibt es verschiedene Lösungsansätze. Diese reichen von gemeindebasierten Initiativen und internationaler Zusammenarbeit bis hin zu Gerichtsverfahren und politischen Maßnahmen. Ein wichtiger Schritt dabei ist es, die historische Verantwortung anzuerkennen und den globalen Norden zur Verantwortung zu ziehen. Ein Schuldenerlass für die Länder des globalen Südens könnte ihnen zudem finanzielle Ressourcen verschaffen, die sie in umweltfreundliche Technologie stecken können.Mit diesem Beitrag soll ein Bewusstsein für Umweltrassismus geschaffen werden. Das Ziel ist es, dass weniger CO2 freigesetzt wird, um eine nachhaltige Welt zu schaffen, in der Umweltressourcen und Chancen fair verteilt werden und niemand aufgrund seiner Hautfarbe oder seines sozialen Status benachteiligt wird. Es erfordert Engagement auf individueller und globaler Ebene, um die notwendigen Veränderungen herbeizuführen.LiteraturverzeichnisAdick, Katharina (2022): SPEZIAL: Klimagerechtigkeit – So wird Klimaschutz sozialer (Audio-Podcast). 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AMÉRICA LATINA Desastres naturales dejan cientos de muertos en México. Para más información:http://www.chinadaily.com.cn/photo/2013-09/23/content_16987950.htmhttp://www.cnn.com/2013/09/15/world/americas/tropical-weather/index.htmlhttp://www.bbc.co.uk/news/world-latin-america-24203404http://www.eltiempo.com/mundo/latinoamerica/47-muertos-en-desastre-por-lluvias-http://worldnews.nbcnews.com/_news/2013/09/18/20554314-looting-hits-acapulco-as-mexico-storm-death-toll-reaches-80?litecausadas-por-ciclones-ingrid-y-manuel-en-mxico_13069068-4http://www.lanacion.com.ar/1621210-crece-la-desesperacion-en-acapulco-por-un-ciclonhttp://www.lemonde.fr/planete/article/2013/09/22/mexique-apres-les-tempetes-le-defi-de-la-reconstruction_3482394_3244.htmlhttp://internacional.elpais.com/internacional/2013/09/19/actualidad/1379621833_362444.html Fuertes lluvias y tornado afectan a miles de personas en Brasil. Para más información:http://www.lanacion.com.ar/1622524-un-tornado-deja-dos-muertos-64-heridos-y-cien-casas-destruidas-en-brasilhttp://www.bbc.co.uk/mundo/ultimas_noticias/2013/09/130923_ultnot_brazil_lluvias_ng.shtml Al menos 16 muertos deja motín en cárcel de Venezuela. Para más información:http://www.bbc.co.uk/news/world-latin-america-24135414http://www.eltiempo.com/mundo/latinoamerica/motn-en-crcel-de-en-crcel-de-sabaneta-estado-zulia-venezuela_13067995-4http://www.lanacion.com.ar/1620826-16-muertos-en-un-nuevo-motin-en-una-carcel-de-venezuelahttp://www.eltiempo.com/mundo/latinoamerica/venezuela-en-el-centro-de-la-polemica-por-las-narcomaletas_13079895-4 Vuelo de Air France transportó cocaína valuada en $270 millones de dólares. Para más información:http://www.lanacion.com.ar/1622606-narcovalijas-otro-extrano-caso-que-asombra-a-venezuelahttp://internacional.elpais.com/internacional/2013/09/21/actualidad/1379720594_991194.htmlhttp://www.cnn.com/2013/09/22/world/europe/air-france-cocaine-found/index.html?hpt=wo_t3http://worldnews.nbcnews.com/_news/2013/09/21/20627626-270-million-worth-of-cocaine-seized-from-air-france-flight?litehttp://www.chinadaily.com.cn/world/2013-09/23/content_16986361.htm Dilma realiza polémico discurso en sede de la ONU. Para más información:http://oglobo.globo.com/mundo/autoridades-se-dividem-sobre-discurso-de-dilma-na-onu-contra-espionagem-americana-10127164#ixzz2frl2tyP1 http://www.miamiherald.com/2013/09/23/3646392/for-brazilians-president-rousseff.htmlhttp://www.lanacion.com.ar/1622822-dilma-rousseff-dijo-en-la-onu-que-eeuu-quebro-el-derecho-internacional-con-su-programa-de-eshttp://www.cnn.com/2013/09/17/world/americas/brazil-us/index.htmlhttp://www.bbc.co.uk/portuguese/noticias/2013/09/130923_dilma_onu_pu_dg.shtml Turbulencias políticas en la coalición de gobierno del PT en Brasil. Para más información:http://internacional.elpais.com/internacional/2013/09/20/actualidad/1379638800_371434.htmlhttp://www.lanacion.com.ar/1621229-turbulencias-politicas-en-la-coalicion-de-gobierno-del-pt Venezuela: el papel higiénico bajo control militar. Para más información:http://www.cnn.com/2013/09/21/world/americas/venezuela-toilet-paper/index.htmlhttp://www.eltiempo.com/mundo/latinoamerica/venezuela-dice-que-ee-uu-prohibi-vuelo-de-maduro-sobre-puerto-rico_13071990-4http://www.lanacion.com.ar/1622118-el-papel-higienico-bajo-control-militarhttp://internacional.elpais.com/internacional/2013/09/21/actualidad/1379731784_337540.html Estados Unidos niega a Maduro el uso de su espacio aéreo. Para más información:http://www.bbc.co.uk/news/world-latin-america-24173124http://www.cnn.com/2013/09/20/world/americas/venezuela-us-presidential-plane/index.html Cristina Fernández en la ONU: "No se puede vivir en un mundo donde todo dependa de lo que resuelvan una o dos personas". Para más información:http://www.bbc.co.uk/mundo/ultimas_noticias/2013/09/130924_ultnot_cristina_fernandez_mr.shtml Maduro viaja a China para buscar préstamo por 390 millones de dólares. Para más información:http://www.chinadaily.com.cn/world/2013-09/23/content_16985752.htm http://www.eltiempo.com/mundo/latinoamerica/viaje-de-nicols-maduro-a-china_13074455-4 Andrés Oppenheimer analiza: "Venezuela sigue alentando dictador sirio". Para más información:http://www.miamiherald.com/2013/09/18/3635418/andres-oppenheimer-venezuela-keeps.html ESTADOS UNIDOS /CANADÁ Dos tiroteos horrorizan a Estados Unidos. Para más información:http://www.lemonde.fr/ameriques/article/2013/09/23/obama-plaide-pour-une-modification-de-la-legislation-des-armes-a-feu_3482532_3222.htmlhttp://www.eltiempo.com/mundo/estados-unidos/aaron-alexis-el-atacante-en-instalacin-naval-de-washington_13067238-4http://www.lanacion.com.ar/1620538-otro-tiroteo-horroriza-a-eeuu-13-muertos-en-pleno-washingtonhttp://www.eltiempo.com/mundo/estados-unidos/tiroteo-en-chicago_13072703-4http://www.lanacion.com.ar/1621649-otro-tiroteo-en-estados-unidos-varias-personas-baleadas-en-un-parque-de-chicago Obama urge a retomar ley de control de armas de fuego. Para más información:http://www.eluniversal.com.mx/el-mundo/2013/obama-ley-armas-952747.html Obama busca un éxito para salir de su mal momento: quedó debilitado por la crisis siria, el escándalo Snowden y traspiés en el Congreso Para más información:http://www.lanacion.com.ar/1622100-obama-busca-un-exito-para-salir-de-su-mal-momento La Cámara de Representantes aprueba dejar sin fondos el sistema sanitario. Para más información:http://internacional.elpais.com/internacional/2013/09/20/actualidad/1379690784_897214.html Impactantes imágenes de las inundaciones en Colorado. Para más información:http://www.lanacion.com.ar/1620424-impactantes-imagenes-de-las-inundaciones-en-colorado Obama 'No creo que acción militar lleve a la paz duradera en Siria'. Para más información:http://www.eltiempo.com/mundo/estados-unidos/obama-dice-que-una-accin-militar-no-llevar-paz-en-siria_13079460-4 Piden a Estados Unidos arrestar al presidente de Sudán. Para más información:http://www.eluniversal.com.mx/el-mundo/2013/piden-a-eu-arrestar-al-presidente-de-sudan-951913.html Sorpresa y alivio en los mercados: la Fed mantiene sus estímulos. Para más información:http://www.bbc.co.uk/portuguese/noticias/2013/09/130923_banco_central_ru.shtmlhttp://www.lanacion.com.ar/1621206-sorpresa-y-alivio-en-los-mercados-la-fed-mantiene-sus-estimulos Fatal accidente entre un tren y un ómnibus en Canadá. Para más información:http://worldnews.nbcnews.com/_news/2013/09/18/20560490-six-killed-after-train-collides-with-bus-in-canadas-capital?litehttp://www.lanacion.com.ar/1621041-fatal-accidente-entre-un-tren-y-un-colectivo-en-canadahttp://www.cnn.com/2013/09/18/world/americas/canada-bus-train-colllision/index.html?hpt=wo_bn5 El secretario general Ban Ki-Moon abrió la 68° sesión de debate con un mensaje sobre la crisis en Siria. Para más información:http://www.lanacion.com.ar/1622801-en-vivo-comenzo-la-reunion-de-la-asamblea-general-de-la-onu EUROPA Ángela Merkel obtiene victoria histórica en elecciones en Alemania. Para más información:http://www.latimes.com/world/la-fg-germany-election-20130923,0,1525699.storyhttp://www.bbc.co.uk/news/world-europe-24203909http://www.economist.com/blogs/charlemagne/2013/09/german-election-diary-6http://www.cnn.com/2013/09/22/world/europe/germany-elections/index.html?hpt=wo_c2http://worldnews.nbcnews.com/_news/2013/09/23/20656028-germanys-angela-merkel-celebrates-super-result-after-securing-third-term?litehttp://www.lanacion.com.ar/1622594-merkel-con-dificultades-para-formar-una-coalicionhttp://oglobo.globo.com/mundo/apos-selecao-multicultural-de-futebol-alemanha-tem-primeiros-negros-no-parlamento-10104002#ixzz2frq3kPmV http://internacional.elpais.com/internacional/2013/09/22/actualidad/1379834875_690573.htmlhttp://www.nytimes.com/2013/09/23/world/europe/germany-elections.html?ref=world&gwh=85DE080B13C14B847AF7298B3279080F Barco de Greenpeace contra intereses rusos. Para más información:http://www.bbc.co.uk/news/world-europe-24222392http://www.bbc.co.uk/news/business-24194726http://www.cnn.com/2013/09/20/world/europe/russia-greenpeace/index.html?hpt=ieu_c2 Pussy Riot en huelga de hambre por malas condiciones carcelarias en Rusia. Para más información:http://www.latimes.com/world/worldnow/la-fg-wn-pussy-riot-hunger-strike-prison-20130923,0,553029.story Ataque a edificio de policía en Ankara. Para más información:http://www.bbc.co.uk/news/world-europe-24184381 Snowden revela que Reino Unido usó un virus para espiar en Bélgica. Para más información:http://internacional.elpais.com/internacional/2013/09/20/actualidad/1379676659_653447.html Holanda pone fin al Estado de Bienestar. Para más información:http://www.lanacion.com.ar/1620849-holanda-pone-fin-al-estado-de-bienestarhttp://internacional.elpais.com/internacional/2013/09/21/actualidad/1379759516_595505.html Putin no descarta presentarse a la reelección. Para más información:http://www.eluniversal.com.mx/el-mundo/2013/rusia-putin-reeleccion-952002.html Los suizos rechazan en las urnas la abolición del servicio militar obligatorio. Para más información:http://www.nytimes.com/2013/09/23/world/europe/swiss-vote-to-keep-mandatory-army-service.html?ref=world&gwh=E7F8DD8A869141BB79F7E688A1911531http://internacional.elpais.com/internacional/2013/09/22/actualidad/1379845725_584652.htmlhttp://internacional.elpais.com/internacional/2013/09/21/actualidad/1379761520_791558.html ASIA- PACÍFICO/ MEDIO ORIENTE Continúa la sangrienta guerra civil en Siria. Para más información:http://www.lemonde.fr/proche-orient/article/2013/09/20/l-offensive-mediatique-de-bachar-al-assad_3481937_3218.htmlhttp://www.latimes.com/world/la-fg-syria-weapons-20130924,0,4157401.storyhttp://www.bbc.co.uk/news/world-asia-india-24217703http://www.cnn.com/2013/09/23/world/meast/syria-civil-war/index.html?hpt=wo_c2http://internacional.elpais.com/internacional/2013/09/14/actualidad/1379158714_684648.htmlhttp://www.lanacion.com.ar/1622604-el-conflicto-sirio-y-el-acercamiento-entre-iran-y-eeuu-los-ejes-de-la-asamblea-de-la-onu#comentarhttp://elcomercio.pe/actualidad/1635129/noticia-bashar-al-assad-siria-enemigo-imaginario-potencias-occidente?ft=gridhttp://www.cnn.com/2013/09/16/world/meast/syria-whats-next/index.html?hpt=wo_bn8http://www.latimes.com/local/columnone/la-fg-c1-syria-rebuild-20130924-dto,0,6358208.htmlstory Más de 4.000 niños han abandonado Siria sin sus padres según Unicef. Para más información:http://www.eltiempo.com/mundo/medio-oriente/ms-de-4000-nios-han-abandonado-siria-solos-segn-unicef_13072878-4 Ataque suicida en una iglesia cristiana en Pakistán deja 78 muertos. Para más información:http://www.bbc.co.uk/news/world-asia-24201243http://www.latimes.com/world/la-fg-pakistan-church-20130923,0,6344281.storyhttp://worldnews.nbcnews.com/_news/2013/09/23/20655580-angry-christians-protest-pakistan-church-bombing-death-toll-rises-to-81?litehttp://www.eltiempo.com/mundo/asia/nio-paquistan-fue-violado-por-el-director-de-un-jardn-y-otros-cuatro-hombres_13072884-4http://www.lanacion.com.ar/1622318-ataque-suicida-en-una-iglesia-cristiana-en-paquistanhttp://internacional.elpais.com/internacional/2013/09/22/actualidad/1379846926_053319.htmlhttp://www.lemonde.fr/asie-pacifique/article/2013/09/22/25-morts-dans-un-attentat-suicide-devant-une-eglise-au-pakistan_3482419_3216.html Pakistán pone en libertad al ex número dos de los talibanes. Para más información:http://www.latimes.com/world/la-fg-afghanistan-pakistan-taliban-20130922,0,3915020.story Cadena perpetua para ex líder chino Bo Xilai. Para más información:http://www.lemonde.fr/asie-pacifique/article/2013/09/22/la-condamnation-de-bo-xilai-a-la-perpetuite-passionne-la-blogosphere-chinoise_3482507_3216.htmlhttp://www.cnn.com/2013/09/23/world/asia/china-bo-xilai/index.html?hpt=wo_c2http://www.lanacion.com.ar/1622319-dura-condena-contra-un-ex-lider-chinohttp://www.eltiempo.com/mundo/asia/cadena-perpetua-para-exlder-chino-bo-xilai_13077445-4http://behindthewall.nbcnews.com/_news/2013/09/19/20582910-ousted-chinese-politician-bo-xilai-found-guilty-sentenced-to-life-in-prison?litehttp://www.bbc.co.uk/news/world-asia-24203461 Corea del Norte y constantes pruebas de desarrollo bélico. Para más información:http://www.latimes.com/world/worldnow/la-fg-wn-north-korea-cancels-family-reunions-20130921,0,3720420.storyhttp://www.economist.com/news/asia/21586593-north-korea-appears-be-firing-up-its-old-nuclear-reactor-picking-up-steam Los crueles abusos en Corea del Norte preocupan a la ONU. Para más información:http://www.eltiempo.com/mundo/asia/investigacin-de-la-onu-condena-abusos-generalizados-en-corea-del-norte_13066998-4http://www.cnn.com/2013/09/21/world/asia/korea-family-reunions-cancel/index.html?hpt=wo_t2http://internacional.elpais.com/internacional/2013/09/21/actualidad/1379749345_852336.htmlhttp://www.lemonde.fr/asie-pacifique/article/2013/09/21/la-coree-du-nord-reporte-les-rencontres-de-familles-separees-par-la-guerre_3482131_3216.html Mas de 60 muertos en atentado en funeral en Irak. Para más información:http://www.lemonde.fr/proche-orient/article/2013/09/21/irak-l-explosion-de-voitures-piegees-fait-au-moins-huit-morts_3482358_3218.htmlhttp://www.cnn.com/2013/09/20/world/meast/iraq-violence/index.html?hpt=imi_c2http://www.economist.com/blogs/analects/2013/09/boxilai-sentencehttp://www.bbc.co.uk/news/world-middle-east-24190728http://www.nytimes.com/2013/09/23/world/middleeast/bomber-hits-sunni-funeral-as-attacks-mount-in-iraq.html?ref=world&gwh=7C5D659AC487AAC0D98E436F0B226EB0 Diversos medios cubrieron desastres naturales que afectaron a China, Tailandia y Filipinas. Para más información:http://www.bbc.co.uk/news/world-asia-24193201http://www.cnn.com/2013/09/15/world/meast/yemen-child-bride/index.html?hpt=wo_bn8http://www.cnn.com/2013/09/22/world/asia/typhoon-usagi/index.html?hpt=wo_c2http://worldnews.nbcnews.com/_news/2013/09/22/20638844-twenty-dead-after-powerful-typhoon-lashes-hong-kong?litehttp://www.nytimes.com/2013/09/23/world/middleeast/netanyahu-is-said-to-view-iran-deal-as-a-possible-http://oglobo.globo.com/mundo/chuvas-causam-mortes-deixam-11-mil-desabrigados-nas-filipinas-10132622#ixzz2frr34vRwhttp://www.lemonde.fr/planete/article/2013/09/22/apres-les-philippines-et-taiwan-un-super-typhon-menace-hong-kong_3482399_3244.htmlhttp://www.chinadaily.com.cn/world/2013-09/18/content_16980115.htm Al menos 56 uniformados muertos en ataques de Al Qaeda en Yemen. Para más información:http://www.eltiempo.com/mundo/medio-oriente/56-uniformados-muertos-en-ataques-de-al-qaida-en-yemen_13072837-4 Desafortunados sucesos denotan pesimismo sobre negociaciones de paz en Medio Oriente. Para más información:http://www.bbc.co.uk/news/world-middle-east-24200443http://www.latimes.com/world/worldnow/la-fg-wn-poll-israel-palestinian-peace-negotiations-20130923,0,1612663.storyhttp://www.chinadaily.com.cn/world/2013-09/23/content_16986672.htm Diplomacia iraní intenta tener rol fundamental en Asamblea de la ONU. Para más información:http://www.lemonde.fr/proche-orient/article/2013/09/22/rohani-veut-la-reconnaissance-du-droit-de-l-iran-a-enrichir-l-uranium_3482409_3218.htmlhttp://www.bbc.co.uk/news/world-middle-east-24210066http://www.economist.com/news/middle-east-and-africa/21586598-irans-new-president-launches-unprecedented-charm-offensive-his-biggest-smilehttp://www.cnn.com/2013/09/23/world/asia/un-general-assembly/index.html?hpt=wo_c2 Un fuerte terremoto de 7,7 grados dejó al menos 80 muertos en Pakistán. Para más información:http://www.lanacion.com.ar/1622893-un-fuerte-terremoto-de-77-grados-dejo-al-menos-80-muertos-en-pakistan Elecciones en Sri Lanka. Para más información:http://www.economist.com/blogs/banyan/2013/09/elections-sri-lanka El 'boom' asiático destrona el popular 'made in China'. Para más información:http://www.eltiempo.com/mundo/asia/el-boom-asitico-destrona-el-popular-made-in-china_13073899-4 ÁFRICA Ataque a centro comercial en Kenia. Para más información:http://www.nytimes.com/2013/09/23/world/africa/nairobi-mall-shooting.html?ref=world&_r=0&gwh=1BE77FB8E179607237AC38DB7471AE95http://www.lemonde.fr/afrique/article/2013/09/23/le-kenya-theatre-de-nombreuses-attaques-terroristes_3482543_3212.htmlhttp://www.eluniversal.com.mx/el-mundo/2013/aumenta-a-68-cifra-de-muertos-en-nairobi-952782.htmlhttp://oglobo.globo.com/mundo/presidente-do-quenia-afirma-ter-derrotado-terroristas-em-shopping-10114658#ixzz2frsOPhXmhttp://www.latimes.com/world/worldnow/la-fg-wn-kenya-mall-attack-gunmen-alive-20130924,0,7047934.storyhttp://www.bbc.co.uk/news/world-africa-24179992http://www.economist.com/blogs/baobab/2013/09/attack-kenya-0http://www.cnn.com/2013/09/23/world/africa/kenya-mall-attack/index.html?hpt=wo_c1http://worldnews.nbcnews.com/_news/2013/09/24/20669256-kenya-mall-attack-survivor-we-were-let-down-by-the-police?litehttp://www.miamiherald.com/2013/09/22/3643048/attackers-remain-in-kenya-mall.htmlhttp://www.chinadaily.com.cn/world/2013-09/23/content_16985804.htm Cierran el metro de El Cairo tras encontrar dos bombas sin explotar. Para más información:http://www.eltiempo.com/mundo/medio-oriente/cierran-el-metro-de-el-cairo-tras-encontrar-dos-bombas_13071296-4 La violencia persigue a los refugiados sirios hasta Egipto. Para más información:http://internacional.elpais.com/internacional/2013/09/21/actualidad/1379781812_737789.html Egipto prohíbe actividades de los Hermanos Musulmanes. Para más información:http://www.cnn.com/2013/09/23/world/africa/egypt-muslim-brotherhood/index.html?hpt=wo_c2http://worldnews.nbcnews.com/_news/2013/09/23/20659049-egypt-court-bans-all-muslim-brotherhood-activities?lite OTRAS NOTICIAS En el mundo existen 168 millones de niños que se ven obligados a trabajar. Para más información:http://www.eltiempo.com/mundo/europa/informe-de-la-oit-progresos-contra-el-trabajo-infantil_13077838-4 "Los Angeles Times" presenta portal sobre el crecimiento de la población mundial. Para más información:http://www.latimes.com/news/nationworld/world/population/ "The Economist" presenta su informe semanal: "Business this week". Para más información:http://www.economist.com/news/world-week/21583302-business-week

India víctima del terrorismo El pasado 26 de noviembre ocurrieron diez ataques terroristas coordinados en Bombay, capital financiera ubicada al este de India.Unas 155 personas han muerto, incluyendo 6 extranjeros, y 327 resultaron heridas. La operación fue reivindicada por un grupo islamista poco conocido: los Muyahidines del Decán.El pasado martes al menos tres personas murieron y 29 resultaron heridas al explotar una bomba en un vagón de tren en el noroeste de India Varios medios informan al respecto:"El País" de Madrid:"India crea un organismo federal antiterrorista: Dimite el ministro del Interior por la tardía respuesta al ataque de Bombay": http://www.elpais.com/articulo/internacional/Rice/urge/Pakistan/colaborar/investigacion/atentados/Bombay/elpepuint/20081201elpepuint_3/Tes"Los terroristas de Bombay fueron entrenados en dos bases de Pakistán": http://www.elpais.com/articulo/internacional/terroristas/Bombay/fueron/entrenados/bases/Pakistan/elpepiint/20081202elpepiint_4/Tes"El Gobierno indio acusa del ataque a Bombay a terroristas "de fuera":El primer ministro indio dice que los terroristas tenían su base en el exterior de India, en alusión a Pakistán.- Tres de los detenidos confiesan su pertenencia a un grupo islámico paquistaní": http://www.elpais.com/articulo/internacional/Gobierno/indio/acusa/ataque/Bombay/terroristas/fuera/elpepuint/20081128elpepuint_8/Tes"New York Times":"Analysts Say It Will Be Difficult to Shield Luxury Hotels From Terrorist Attacks":http://www.nytimes.com/2008/12/01/world/asia/01hotel.html?ref=world"Cabinet Minister Resigns in Wake of India Attacks":http://www.nytimes.com/2008/12/01/world/asia/01mumbai.html"Le Monde":"L'Inde proteste officiellement auprès du Pakistan après les attentats":http://www.lemonde.fr/asie-pacifique/article/2008/12/01/l-inde-proteste-officiellement-aupres-du-pakistan-apres-les-attentats_1125630_3216.html#ens_id=1123577"Le processus de paix indo-pakistanais menacé":http://www.lemonde.fr/asie-pacifique/article/2008/12/01/le-processus-de-paix-indo-pakistanais-menace_1125382_3216.html#ens_id=1123577"La cohésion confessionnelle, principal enjeu de l'après-Bombay en Inde":http://www.lemonde.fr/international/son/2008/12/01/la-cohesion-confessionnelle-principal-enjeu-de-l-apres-bombay-en-inde_1125618_3210.html#ens_id=1123577"CNN"Presenta sitio web con artículos relacionados a los atentados: http://edition.cnn.com/SPECIALS/2008/news/mumbai.attacks/"Hand over militants, India tells Pakistan":http://edition.cnn.com/2008/WORLD/asiapcf/12/02/india.attacks/index.html"BBC":"EE.UU. "advirtió" a India sobre Bombay": http://news.bbc.co.uk/hi/spanish/international/newsid_7761000/7761477.stm"Bombay, una mexicana y un sueño roto": http://news.bbc.co.uk/hi/spanish/international/newsid_7761000/7761172.stm"MSNBC""Official: Train blast kills 3, wounds 29 in India: Bombing in insurgency-hit area not thought to be linked to Mumbai attacks":http://www.msnbc.msn.com/id/28009719/"U.S. official: Indian attack has Pakistani ties: Washington says it warned of possible waterborne attack on Mumbai": http://www.msnbc.msn.com/id/28015877/"La Nación":"India pidió a Paquistán la extradición de 20 presuntos terroristas: Realizó el pedido formal y aguarda la respuesta oficial del país vecino; es por la ola de atentados en Bombay":http://www.lanacion.com.ar/nota.asp?nota_id=1076532"Los hoteles de lujo, un imán para los terroristas: Los expertos advierten que es muy difícil convertirlos en fortalezas":http://www.lanacion.com.ar/nota.asp?nota_id=1076392"EL Universal" de México:"Al menos tres muertos por nueva bomba en India: El tren viajaba desde Lumding, en la provincia central de Assam, con destino al activo centro comercial de Tinsukhia, en el este, dijo Sahu":http://www.eluniversal.com.mx/notas/559859.html"Ofrece Pakistán a India una comisión sobre ataque a Bombay: El ministro de Exteriores paquistaní reiteró la intención de su Gobierno de cooperar para llevar ante la Justicia a quienes perpetraron ese atroz acto terrorista": http://www.eluniversal.com.mx/notas/559767.html"The Economist": "India under attack: A terrorist onslaught of stunning scope and horror": http://www.economist.com/world/asia/displaystory.cfm?story_id=12708194"Los Ángeles Times":"In Mumbai, terrorists and survivors sought":http://www.latimes.com/news/nationworld/world/la-fg-mumbai28-2008nov28,0,3880571.story"India terrorist attacks leave at least 101 dead in Mumbai":http://www.latimes.com/news/printedition/front/la-fg-mumbai27-2008nov27,0,4127780.story "Miami Herald":"Landmark Mumbai hotel targeted in terrorist spree":http://www.miamiherald.com/business/breaking-news/story/789813.html"Timeline for Mumbai terrorist attacks":http://www.miamiherald.com/691/story/790274.html"Times":"Mumbai attacks - city fears five terrorists are 'missing'":http://www.timesonline.co.uk/tol/news/world/asia/article5265938.ece"'Free our Mujahideens' demand Bombay terrorists":http://www.timesonline.co.uk/tol/news/world/asia/article5242602.eceAMERICA LATINA"MSNBC" informe: "37 killed in Tijuana over 3 days: Toll includes 4 children and 9 decapitated men; police chief fired":http://www.msnbc.msn.com/id/27990143/"MSNBC" anuncia: "Mexican president vows to clean up corruption: He also pledges to never negotiate with drug lords": http://www.msnbc.msn.com/id/27984780/"Le Monde" publica: "Venezuela : Hugo Chavez se voit gouverner "jusqu'en 2019, jusqu'en 2021":http://www.lemonde.fr/ameriques/article/2008/12/01/venezuela-hugo-chavez-se-voit-gouverner-jusqu-en-2019-jusqu-en-2021_1125392_3222.html#ens_id=1120093"CNN" plantea: "Chavez again seeks way past term limit":http://edition.cnn.com/2008/WORLD/americas/11/30/venezuela.chavez.vote/index.html"BBC" anuncia: "Venezuela: enmienda con fecha":http://news.bbc.co.uk/hi/spanish/latin_america/newsid_7759000/7759907.stm"El País" de Madrid informa: "Hugo Chávez reabre el proceso para su reelección indefinida: El líder venezolano ignora la consulta que tumbó la reforma constitucional": http://www.elpais.com/articulo/internacional/Hugo/Chavez/reabre/proceso/reeleccion/indefinida/elpepuint/20081130elpepuint_11/Tes"La Nación" anuncia: "Reelección en Venezuela: Chávez: "Empieza la ofensiva"": http://www.lanacion.com.ar/nota.asp?nota_id=1076471"El País" de Madrid informa: "La asignatura pendiente de Brasil: Lula no ha cumplido su promesa de un reparto justo de tierras cultivables": http://www.elpais.com/articulo/internacional/asignatura/pendiente/Brasil/elpepuint/20081201elpepuint_4/Tes"CNN" publica: "Brazil officials track disease from flood-tainted water":http://edition.cnn.com/2008/WORLD/americas/12/02/brazil.floods/index.html"CNN" plantea: "Chileans angry over Peru general's 'body bag' remark":http://edition.cnn.com/2008/WORLD/americas/12/01/peru.chile/index.html"La Nación" publica: "La nueva vida de Ingrid, entre viajes y reuniones: Antes de su visita a América latina, la ex rehén recorrió varios países, fue recibida por importantes líderes y distinguida con varios galardones":http://www.lanacion.com.ar/nota.asp?nota_id=1076579"The Economist" analiza: "Latin American diplomacy: Friends of opportunity. China, rather than Russia, is the new partner that matters":http://www.economist.com/world/americas/displaystory.cfm?story_id=12684849ESTADOS UNIDOS-CANADA"El País" de Madrid informa: "Obama confirma a Hillary Clinton como secretaria de Estado: Robert Gates seguirá al frente de Defensa.- El presidente electo anuncia los nombres que tendrán la misión de recuperar la credibilidad de EE UU en el mundo": http://www.elpais.com/articulo/internacional/Obama/confirma/Hillary/Clinton/secretaria/Estado/elpepuint/20081201elpepuint_9/Tes"BBC" analiza: "¿Líder antiguerra, gabinete bélico?: Tras semanas de especulación, de críticas y elogios adelantados, el presidente electo de Estados Unidos, Barack Obama, le presentó al mundo su equipo de Relaciones Exteriores, y describió a quienes lo conforman como individuos con "fuertes personalidades" para desatar "vigorosos debates".":http://news.bbc.co.uk/hi/spanish/international/newsid_7759000/7759630.stm"El Universal" de México informa: "Obama plantea "nuevo liderazgo": Reitera su intención de sacar tropas de Irak en 16 meses": http://www.eluniversal.com.mx/internacional/59785.html"El Mercurio" de Chile anuncia: "La gran oportunidad de Hillary para hacer gala de sus credenciales : Analistas coinciden en que la "marca registrada" de Clinton y la popularidad de Obama a nivel internacional lograrán mejorar la imagen de EE.UU. en el mundo.":http://diario.elmercurio.com/2008/12/02/internacional/internacional/noticias/86FA1457-7630-45F2-A88D-5D76D7644465.htm?id={86FA1457-7630-45F2-A88D-5D76D7644465}"La Nación" publica: "Gobernadores con cuentas en rojo se reunieron con Obama: El presidente electo norteamericano atendió solicitudes de miles de millones de dólares para financiar la atención médica y proyectos de infraestructura en sus estados":http://www.lanacion.com.ar/nota.asp?nota_id=1076626"BBC" plantea: "Bush defiende su gestión: A poco más de un mes de dejar la Casa Blanca, el saliente presidente de Estados Unidos George W. Bush defendió su gestión diciendo que tomó decisiones difíciles, pero que no comprometió sus principios.":http://news.bbc.co.uk/hi/spanish/international/newsid_7759000/7759902.stm"La Nación" anuncia: "Bush confesó que cometió su mayor error en Irak: El presidente de EE.UU. indicó a ABC News que no debió confiar en los informes de inteligencia que indicaban que Saddam Hussein tenía armas de destrucción masiva":http://www.lanacion.com.ar/nota.asp?nota_id=1076597"La Nación" informa: "Temen un ataque terrorista con armas biológicas antes de 2013: Un estudio efectuado durante seis meses por el Congreso norteamericano concluyó también que hay "materiales nucleares" en todo el mundo que están "pobremente protegidos" y que podrían ser utilizados en atentados":http://www.lanacion.com.ar/nota.asp?nota_id=1076664EUROPA"El País" de Madrid informa: "'L'acqua alta' inunda Venecia: Las fuertes lluvias de los últimos días y el viento del sur provocan una subida del nivel del agua que deja bajo el agua gran parte de la ciudad": http://www.elpais.com/articulo/internacional/L/acqua/alta/inunda/Venecia/elpepuint/20081201elpepuint_8/Tes"CNN" anuncia: "Italian police arrest suspects for alleged terror plot":http://edition.cnn.com/2008/WORLD/europe/12/02/milan.terror.suspects/index.html"El País" de Madrid publica imágenes sobre la inundación en Venecia:http://www.elpais.com/fotogaleria/Venecia/desbordada/agua/6008-1/elpgal/"CNN" plantea: "Romania parties in coalition talks after vote":http://edition.cnn.com/2008/WORLD/europe/12/02/romania.vote.ap/index.html"El Mercurio"de Chile informa: "Rusia modernizará sus misiles en respuesta a escudo espacial : El objetivo es lograr que las ojivas puedan volar fuera del alcance del sistema de defensa de EE.UU. También se planea adquirir proyectiles capaces de atravesarlo.":http://diario.elmercurio.com/2008/12/02/internacional/_portada/noticias/A30128DD-96AA-42BC-8578-0A39E4F809E0.htm?id={A30128DD-96AA-42BC-8578-0A39E4F809E0}"CNN" anuncia: "EU probes causes of Georgian conflict":http://edition.cnn.com/2008/WORLD/europe/12/02/georgia.eu.war/index.htmlAsia – Pacífico /Medio OrieNTE"El País" de Madrid informa: "Diecinueve muertos en dos ataques suicidas en Pakistán y Afganistán":http://www.elpais.com/articulo/internacional/Diecinueve/muertos/ataques/suicidas/Pakistan/Afganistan/elpepuint/20081201elpepuint_7/Tes"New York Times" plantea: "In Wake of Attacks, India-Pakistan Tensions Increase":http://www.nytimes.com/2008/12/02/world/asia/02mumbai.html?hp"BBC" publica: "Opositores dejan el aeropuerto":http://news.bbc.co.uk/hi/spanish/international/newsid_7761000/7761563.stm"New York Times" anuncia: "Thai Protesters to Focus on Airports":http://www.nytimes.com/2008/12/02/world/asia/02thai.html?hp"CNN" informa: "Thai protesters to end siege as PM ousted":http://edition.cnn.com/2008/WORLD/asiapcf/12/02/thailand.protests/index.html"MSNBC" analiza: "Thai leader ousted; airports to reopen: Ruling parties dissolved over fraud; anti-government protesters to lift siege":http://www.msnbc.msn.com/id/28007819/"La Nación" publica: "Tailandia: ordenan disolver el partido oficialista e inhabilitan al premier: Lo decidió la Corte Constitucional acusándolo de fraude electoral; el primer ministro aceptó el fallo y anunció su alejamiento del cargo":http://www.lanacion.com.ar/nota.asp?nota_id=1076530"CNN" plantea:"Israel buries victims of Mumbai terror attacks":http://edition.cnn.com/2008/WORLD/asiapcf/12/02/india.attacks.israel.funerals/index.html"Israel to free 250 Palestinian prisoners":http://edition.cnn.com/2008/WORLD/meast/11/30/israel.prisoners.ap/index.html"Bombers kill dozens in Iraq":http://edition.cnn.com/2008/WORLD/meast/12/01/iraq.main/index.html"Rocket attack near U.N. site in Baghdad kills 2":http://edition.cnn.com/2008/WORLD/meast/11/29/iraq.main/index.html"MSNBC" anuncia: "Intercambio de cuerpos: Irán e Irak intercambiaron cuerpos de soldados muertos durante la guerra entre ambos países, por primera vez desde la caída de Saddam Hussein y también por vez primera sin intermediarios.":http://news.bbc.co.uk/hi/spanish/international/newsid_7758000/7758533.stm"MSNBC" informa: "Iraqi women seek freedom of roads again: With sharp drop in violence, female drivers venturing behind the wheel":http://www.msnbc.msn.com/id/28007108/AFRICA"El País" de Madrid informa: "Zimbabue sufre una nueva epidemia de cólera: Nueve de diez provincias se encuentran azotadas por la enfermedad.- El líder de la oposición pide la ayuda internacional para superar la crisis": http://www.elpais.com/articulo/internacional/Zimbabue/sufre/nueva/epidemia/colera/elpepuint/20081201elpepuint_10/Tes"CNN" anuncia: "Capital lacks clean water, cholera kills hundreds in Zimbabwe":http://edition.cnn.com/2008/WORLD/africa/12/01/zimbabwe.cholera/index.html"MSNBC" analiza: "Zimbabwe police skirmish with soldiers: Frustration over unpaid wages touches off a riot in capital":http://www.msnbc.msn.com/id/28002804/"CNN" plantea: "Nigeria forces impose peace after deadly riots":http://edition.cnn.com/2008/WORLD/africa/12/01/nigeria.clashes/index.html"BBC" anuncia: "Etiopía anuncia retirada de Somalia: El gobierno de Etiopía informó que retirará sus tropas de Somalia a finales del próximo mes, luego de combatir a insurgentes islamistas durante dos años.": http://news.bbc.co.uk/hi/spanish/international/newsid_7754000/7754688.stm"Le Monde" informa: "L'échec de l'Ethiopie en Somalie promet une victoire aux islamistes":http://www.lemonde.fr/afrique/article/2008/12/01/l-echec-de-l-ethiopie-en-somalie-promet-une-victoire-aux-islamistes_1125387_3212.html#ens_id=1112246"CNN" publica: "No way to stop us, pirate leader says":http://edition.cnn.com/2008/WORLD/africa/12/01/pirate.interview/index.html"La Nación" plantea: "Piratas atacan un crucero turístico con mil pasajeros cerca de Somalía: Los delincuentes llegaron en dos lanchas y comenzaron a disparar; el barco estadounidense logró escapar":http://www.lanacion.com.ar/nota.asp?nota_id=1076545"El Universal" de México publica: "Aprueba ONU combate de piratería en Somalia: Avala que los gobiernos de la región incursionen militarmente en las aguas territoriales de la región para incautar y decomisar las embarcaciones, armas y demás equipo utilizado para cometer actos de piratería": http://www.eluniversal.com.mx/notas/559945.html"MSNBC" informa: "New hope on AIDS in corner of ravaged Africa: Progress in treating disease protects unborn children against infection":http://www.msnbc.msn.com/id/27983459/ECONOMÍA"The Economist" presenta su informe semanal: "Business this week":http://www.economist.com/business/displaystory.cfm?story_id=12705958"CNN" anuncia: "Asian, Pacific stock markets plunge": http://edition.cnn.com/2008/WORLD/asiapcf/12/01/global.markets/index.html"BBC" analiza: "EE.UU.: días de vacas flacas: Una prestigiosa organización de análisis en temas económicos de Estados Unidos dice que el país ya se encuentra oficialmente en recesión.": http://news.bbc.co.uk/hi/spanish/business/newsid_7759000/7759831.stm"La Nación" publica: "Ya es oficial: EE.UU. está en recesión: Un comité de expertos informó ayer que la contracción comenzó en diciembre de 2007; tras el anuncio, se derrumbó 7% el Dow Jones":http://www.lanacion.com.ar/nota.asp?nota_id=1076460 "China Daily" informa: "US officially in recession, Dow falls sharply": http://www.chinadaily.com.cn/world/2008-12/02/content_7258334.htm"China Daily" plantea: "Oil tumbles below $50 as recession called": http://www.chinadaily.com.cn/world/2008-12/02/content_7259936.htm"The Economist" informa: "The price of oil: Down it goes. The price of oil has fallen below $50 a barrel. Why that may not be entirely welcome news": http://www.economist.com/finance/displayStory.cfm?story_id=12716182&source=features_box_main"The Economist" analiza: "Barack Obama's economic team: Off to work they go: Barack Obama has stacked his cabinet with clever economists, but can they work together? And what will they do?": http://www.economist.com/world/unitedstates/displaystory.cfm?story_id=12685546 OTRAS NOTICIAS"El País" de Madrid publica sección con: "Los 100 iberoamericanos protagonistas del año": http://www.elpais.com/especial/protagonistas/"El País" de Madrid analiza:"Moscú vuelve al Caribe: El presidente ruso Medvédev corteja a Cuba y Venezuela en una gira por América Latina": http://www.elpais.com/articulo/opinion/Moscu/vuelve/Caribe/elpepiopi/20081201elpepiopi_2/Tes"MSNBC" anuncia: "Pirates chase, open fire on U.S. cruise ship: Official: Boat carrying 1,000 passengers 'very fortunate' to escape hijack bid":http://www.msnbc.msn.com/id/28011013/"La Nación" informa: " Rusia desafía a EE.UU. y moderniza sus mísiles: Las armas podrían quebrar el escudo norteamericano de defensa":http://www.lanacion.com.ar/nota.asp?nota_id=1076425"China Daily" publica: "First days after HIV infection may hold vaccine key": http://www.chinadaily.com.cn/world/2008-12/02/content_7259798.htm

El Huracán Gustav se formó en el Caribe la mañana del 25 de agosto al sureste de Puerto Príncipe, Haití. Rápidamente se intensificó en una tormenta tropical esa misma tarde y en un huracán en las primeras horas del día siguiente. Con su paso afectó gravemente a poblaciones de Haití, Republica Dominicana, Jamaica y esta última semana, Cuba y los Estados Unidos. Varios medios informan sobre este suceso y sus repercusiones en diferentes ámbitos: "MSNBC": "Cuba digs out after Gustav's winds hit 212 mph: Homes destroyed and flooded, but no deaths; hurricane set wind record":http://www.msnbc.msn.com/id/26486029/"New Orleans mayor: Don't come home yet: Nagin says it's too early to return after massive hurricane evacuation":http://www.msnbc.msn.com/id/26501363/"MSNBC" presenta sitio con links a noticias relacionadas al paso del huracán: http://www.msnbc.msn.com/id/21134540/vp/22886841#22886841"Gustav may trigger $10B in insurance claims: 'More of a wind event, than a flood event,' says insurance spokesman": http://www.msnbc.msn.com/id/26510099/"Le Monde":"L'ouragan Hanna fait 10 morts à Haïti, déjà frappé par Gustav":http://www.lemonde.fr/ameriques/article/2008/09/02/l-ouragan-hanna-fait-10-morts-a-haiti-deja-frappe-par-gustav_1090770_3222.html#ens_id=1088297"A Lafayette, en Louisiane, "rien n'a changé depuis Katrina"":http://www.lemonde.fr/ameriques/article/2008/09/02/a-lafayette-en-louisiane-rien-n-a-change-depuis-katrina_1090733_3222.html#ens_id=1088297"El Mercurio" de Chile: "Fueron canceladas todas las actividades políticas: Republicanos dedican su primera jornada de convención a los afectados por el huracán":http://diario.elmercurio.com/2008/09/02/internacional/_portada/noticias/3D183F6E-D62D-469D-892E-8DFD8DA361E1.htm?id={3D183F6E-D62D-469D-892E-8DFD8DA361E1}"Gustav pierde fuerza, pero deja siete muertos al golpear a Nueva Orleáns":http://diario.elmercurio.com/2008/09/02/internacional/_portada/noticias/4AC9C805-D662-43B7-BDCF-9E76B1708AB5.htm?id={4AC9C805-D662-43B7-BDCF-9E76B1708AB5}"Miami Herald":"Hurricane Gustav largely spares New Orleans, floods parts of La., Miss.":http://www.miamiherald.com/569/story/668225.html"Los Angeles Times":"After Gustav, Louisiana begins process of recovering":http://www.latimes.com/news/nationworld/nation/la-na-gustav3-2008sep03,0,3455205.story"New Orleans levees hold against Hurricane Gustav":http://www.latimes.com/news/nationworld/nation/la-na-gustav2-2008sep02,0,2668771.story"Republicans scale back convention due to Hurricane Gustav":http://www.latimes.com/news/nationworld/nation/la-na-gop1-2008sep01,0,1600658.story"Hurricane Gustav bears down on empty New Orleáns: Thousands have taken to the highways before the storm, expected to make landfall today as a Category 3.":http://www.latimes.com/news/nationworld/nation/la-na-gustav1-2008sep01,0,1882337.story"The Economist": "Half-empty streets: New Orleans is recovering its energy, but not its people":http://www.economist.com/world/unitedstates/displaystory.cfm?story_id=12009922"The trailers that smelt bad: After the storm, the poisoning"http://www.economist.com/world/unitedstates/displaystory.cfm?story_id=12009914"New York Times":"Powerful Hurricane Lashes Gulf Coast":http://www.nytimes.com/2008/09/02/us/02gustav.html?ref=us"Party's Plans Are Unsettled; McCain Visits Gulf":http://www.nytimes.com/2008/09/01/us/politics/01repubs.html?ref=us"CNN":"CNN" presenta sitio con links a noticias relacionadas al paso del huracán: http://edition.cnn.com/SPECIALS/2008/news/hurricane.gustav/"Oil prices fall sharply as hurricane weakens":http://edition.cnn.com/2008/BUSINESS/09/01/oil.prices.ap/index.html"Gustav hits U.S. economy: Storm is weaker than Katrina three years ago. But it hits an economy that is at greater risk.":http://edition.cnn.com/2008/US/weather/09/01/gustav/index.htmlAMERICA LATINA"CNN" informa: "Bolivia's Morales visits Iran":http://edition.cnn.com/2008/WORLD/americas/09/01/bolivia.iran/index.html"La Nación" informa: "Bolivia: sorpresivo giro de la Corte Electoral contra Evo Morales: El organismo rechazó realizar el referéndum constitucional porque "no fue convocado por ley sino sólo por un decreto"":http://www.lanacion.com.ar/nota.asp?nota_id=1045579"New York Times" informa: "Chávez Threatens to Expel American Ambassador": http://www.nytimes.com/2008/09/01/world/americas/01venez.html?ref=world"El Mercurio" de Chile anuncia: "Chávez podría controlar los blogs y sitios de internet como Facebook": http://diario.elmercurio.com/2008/09/02/internacional/_portada/noticias/981BC888-A155-4AAB-8EE8-0ACA5CC4D76D.htm?id={981BC888-A155-4AAB-8EE8-0ACA5CC4D76D}New York Times" anuncia: "Drug Violence Alters the Flow of Life in Mexico": http://www.nytimes.com/2008/08/31/world/americas/31mexico.html?ref=world"El País" de Madrid publica: "'Marcha blanca' contra el crimen en México: Cientos de miles de ciudadanos reclaman más seguridad ante la imparable ola de violencia": http://www.elpais.com/articulo/internacional/Marcha/blanca/crimen/Mexico/elpepiint/20080901elpepiint_7/Tes"Los Angeles Times" anuncia: "Calderon presents Mexico's annual report in written form: A new law allows President Felipe Calderon to give his state of the nation report without having to appear before Congress, a move that avoids disturbances.":http://www.latimes.com/news/nationworld/world/la-fg-informe2-2008sep02,0,772815.story"La Nación" informa: "Un coche bomba dejó cuatro muertos en Cali: El gobierno de Uribe atribuyó el atentado a las FARC": http://www.lanacion.com.ar/nota.asp?nota_id=1045503"El País" de Madrid informa: "Un coche bomba mata a cinco personas en Colombia: La explosión se produce cerca del Palacio de Justicia de Cali.- La Policía sospecha de las FARC": http://www.elpais.com/articulo/internacional/exodo/Nueva/Orleans/paraliza/campana/EE/UU/elpepuint/20080901elpepiint_1/Tes"La Nación" publica: "Betancourt reclamó un espacio político para las FARC: Sin embargo le pidió a la guerrilla que deje de actuar en forma "terrorista"":http://www.lanacion.com.ar/nota.asp?nota_id=1045634"La Nación" informa: "Ingrid Betancourt, con el Papa": http://www.lanacion.com.ar/nota.asp?nota_id=1045502"El País" de Madrid publica: "Un caso de espionaje agita de nuevo las instituciones de Brasil: Lula promete investigar un escándalo de escuchas telefónicas ilegales al presidente del Supremo y a un senador": http://www.elpais.com/articulo/internacional/caso/espionaje/agita/nuevo/instituciones/Brasil/elpepuint/20080901elpepuint_10/Tes"MSNBC" analiza: "Brazil's spy chief removed over bugging scandal: Wiretaps found on phones of Supreme Court justice, senior politicians": http://www.msnbc.msn.com/id/26505995/"The Economist" analiza: "Brazil: A funny kind of reward. Just when production from Petrobras's big new oilfields gets going, the government ponders changing the rules on oil exploration": http://www.economist.com/world/americas/displaystory.cfm?story_id=12009864"CCN": "Cuban musician guilty of public disorder":http://edition.cnn.com/2008/WORLD/americas/08/29/cuba.punkrocker.ap/index.html"La Nación": "Advirtió Lugo sobre un plan golpista liderado por Oviedo: Involucró también a Duarte Frutos": http://www.lanacion.com.ar/nota.asp?nota_id=1045500"El Mercurio" de Chile informa: "Fernando Lugo denuncia conspiración golpista":http://diario.elmercurio.com/2008/09/02/internacional/internacional/noticias/335949BE-6966-42F4-8C2A-4FEB762D4672.htm?id={335949BE-6966-42F4-8C2A-4FEB762D4672}"Le Monde" publica: "L'Argentine va rembourser sa dette au Club de Paris": http://www.lemonde.fr/ameriques/article/2008/09/02/l-argentine-va-rembourser-sa-dette-au-club-de-paris_1090779_3222.html#ens_id=1090782"La Nación"analiza: "Primera jugada fuerte de Cristina: el Gobierno cancela la deuda con el Club de París con reservas del BCRA: Como ocurrió con el FMI, la Presidenta afirmó que saldará los compromisos de 6700 millones de dólares con fondos del Banco Central ; "esto reafirma una vez más la voluntad de pago de la Argentina", señaló; justificó que este pasivo "no es de carácter financiero" y dijo que el país "necesita confianza"":http://www.lanacion.com.ar/nota.asp?nota_id=1045593"El País" informa sobre gira de Vázquez : "Corea del Sur pidió más apoyo a sus inversiones":http://www.elpais.com.uy/08/09/01/ultmo_367240.aspEl Portal de "Terra" publica: "Vázquez impulsa la exportación de carne a Corea del Sur":http://actualidad.terra.es/nacional/articulo/vazquez-corea-sur-2715888.htESTADOS UNIDOS / CANADA"The Economist" analiza: "John McCain: No surrender. The gnarled maverick outpolls his party and might even beat Barack Obama. But what sort of president would he be?": http://www.economist.com/displaystory.cfm?story_id=12001775"The Economist" informa. "The Democratic convention: Flags, cheers, discipline and doubt. Barack Obama struggled this week to unite his party": http://www.economist.com/world/unitedstates/displaystory.cfm?story_id=12010827"Time" presenta sitio con links a artículos sobre las elecciones estadounidenses: http://thepage.time.com/"Time" anuncia: "Day One at the Republican National Convention": http://www.time.com/time/photogallery/0,29307,1838049,00.html"El Universal" de México publica: "Reanudan Convención Republicana con mensaje de Bush: El presidente Bush, hablará desde la Casa Blanca en una videoconferencia que se transmitirá en el Xcel Energy Center de esta capital de Minnesota": http://www.eluniversal.com.mx/notas/534973.html"BBC" informa: "Republican convention to resume": http://news.bbc.co.uk/2/hi/americas/7594149.stm"Le Monde" informa: "Après un faux départ, la convention républicaine revient au premier plan": http://www.lemonde.fr/elections-americaines/article/2008/09/02/apres-un-faux-depart-la-convention-republicaine-revient-au-premier-plan_1090781_829254.html#ens_id=1089564"La Nación" publica: "Inesperado giro en la campaña republicana: Palin reveló que su hija adolescente está embarazada": http://www.lanacion.com.ar/nota.asp?nota_id=1045463"MSNBC" anuncia: "Palin disclosures raise questions about vetting: Alaskans say no one from McCain camp asked them about eventual VP pick": http://www.msnbc.msn.com/id/26501863/"El País" de Madrid publica: "La convención demócrata no ayuda a Obama en las encuestas: Un sondeo realizado por CNN al finalizar la reunión de Denver revela que mantiene el empate con el republicano John McCain en las preferencias": http://www.elpais.com/articulo/internacional/convencion/democrata/ayuda/Obama/encuestas/elpepuint/20080901elpepuint_18/TesEUROPAVarios medios informan sobre desarrollo del conflicto entre Rusia y Georgia: "New York Times": "E.U. Meets on Georgia Crisis Response": http://www.nytimes.com/2008/09/02/world/europe/02georgia.html?ref=world"El País" de Madrid: "La UE presiona a Rusia para que retire sus tropas de Georgia a niveles previos a la guerra: Sarkozy, Solana y Barroso viajarán a Moscú y Tbilisi la próxima semana para verificar el cumplimiento del acuerdo de alto el fuego.- Medvédev avisa que no dará marcha atrás sobre el reconocimiento de Osetia del Sur y Abjazia": http://www.elpais.com/articulo/internacional/UE/condiciona/nuevas/negociaciones/asociacion/Rusia/retiro/efectivo/tropas/Georgia/elpepuint/20080901elpepuint_11/Tes"La UE busca una posición común frente a Rusia: Brown advierte que "ningún país puede tener el dominio energético de Europa"": http://www.elpais.com/articulo/internacional/UE/busca/posicion/comun/frente/Rusia/elpepuint/20080901elpepiint_5/Tes"CNN":"EU warns Russia against isolation": http://edition.cnn.com/2008/WORLD/europe/09/01/russia.georgia.summit.sanctions/index.html"La Nación": "Las inversiones europeas en Rusia alejan las sanciones: Alemania, Italia y Francia se oponen a cualquier castigo y abogan por un incremento del diálogo con el Kremlin":http://www.lanacion.com.ar/nota.asp?nota_id=1045585"Cumbre europea: Dividida, la UE evita sancionar a Rusia. Le exigió que se retirara de Georgia":http://www.lanacion.com.ar/nota.asp?nota_id=1045504"MSNBC":"Putin vows 'an answer' to NATO ships: Russia has repeatedly complained of Black Sea build-up after Georgia war":http://www.msnbc.msn.com/id/26508298/"EU delays economic, political talks with Russia: Sarkozy says Moscow needs to pull its troops back from Georgia, first": http://www.msnbc.msn.com/id/26497101/"Time""Putin Vows 'Answer' to NATO Ships":http://www.time.com/time/world/article/0,8599,1837975,00.html"EU Talks Tough on Russia": http://www.time.com/time/world/article/0,8599,1837863,00.html"China Daily":"Georgia formally breaks ties with Russia":http://www.chinadaily.com.cn/world/2008-09/02/content_6991967.htm"The Economist" "Russia and Georgia: Put out even more flags: Russia's recognition of South Ossetia and Abkhazia will reverberate for a long time—not least at home": http://www.economist.com/world/europe/displaystory.cfm?story_id=12009856"Time" informa: "Italy Pays Reparations to Libya":http://www.time.com/time/world/article/0,8599,1838014,00.html"La Nación" informa: "Pronostican una recesión en Gran Bretaña: La OCDE que el crecimiento será negativo en los dos últimos trimestres del año, pero indicó que será positivo en 2009; lanzan un paquete para adquirir la primera vivienda": http://www.lanacion.com.ar/nota.asp?nota_id=1045588ASIA – PACÍFICO /MEDIO ORIENTE"New York Times" informa: "Japan's Prime Minister Resigns":http://www.nytimes.com/2008/09/02/world/asia/02japan.html?ref=world"EL País" de Madrid publica: "Dimite el primer ministro de Japón: Yasuo Fukuda, que atravesaba una grave crisis de popularidad, considera que es lo mejor para el país": http://www.elpais.com/articulo/internacional/Dimite/primer/ministro/Japon/elpepuint/20080901elpepuint_13/Tes"MSNBC" anuncia: "Japan's unpopular prime minister resigns: Move throws world's second-largest economy into political confusion": http://www.msnbc.msn.com/id/26495149/"Time" informa: "In Japan, A Strategic Resignation": http://www.time.com/time/world/article/0,8599,1837919,00.html"CNN" anuncia: "Beleaguered Japanese PM resigns":http://edition.cnn.com/2008/WORLD/asiapcf/09/01/japan.pm/index.html"La Nación" publica: "Presentó su dimisión el premier de Japón: Yasuo Fukuda era resistido por el Senado": http://www.lanacion.com.ar/nota.asp?nota_id=1045465"New York Times" publica: "Thai Protesters Target Utilities": http://www.nytimes.com/2008/09/02/world/asia/02thailand.html?ref=world"MSNBC" informa: "Violence sparks Bangkok state of emergency: Thai premier bans gatherings of more than 5 people after deadly protests": http://www.msnbc.msn.com/id/26498577/"La Nación" informa: "Tailandia: declaran el estado de emergencia por la ola de violencia: La crisis política, que derivó en los fuertes enfrentamientos entre oficialistas y opositores, se cobró su primera víctima; el ejército tomó el control de las calles": http://www.lanacion.com.ar/nota.asp?nota_id=1045580"The Economist" publica: "Thailand: No compromise: A three-year political conflict grinds on, as protesters besiege the government": http://www.economist.com/world/asia/displaystory.cfm?story_id=12009966"Los Angeles Times" anuncia: "Thai army takes to streets": http://www.latimes.com/news/nationworld/world/la-fg-thai2-2008sep02,0,2452625.story"Time" informa: "Thai PM Refuses to Step Down":http://www.time.com/time/world/article/0,8599,1837805,00.html"CNN" informa: "Indian flood leaves 3 million needing help":http://edition.cnn.com/2008/WORLD/asiapcf/09/01/india.floods.relief.dead/index.html"MSNBC" analiza: "Disease feared at India flood refugee camps: 250,000 in shelters now, but that could double; cholera, diarrhea feared": http://www.msnbc.msn.com/id/26497562/"CNN" anuncia: "Dalai Lama discharged from Indian hospital": http://edition.cnn.com/2008/WORLD/asiapcf/09/01/india.dalai.lama.ap/index.html"Time" analiza: "The Lessons of the Beijing Olympics":http://www.time.com/time/world/article/0,8599,1835582,00.html"China Daily" publica: "China set to raise poverty line":http://www.chinadaily.com.cn/china/2008-09/03/content_6992004.htm"The Economist" analiza: "Pakistan. Man of the hour: From demented jailbird to president-in-waiting: Asif Zardari's metamorphosis": http://www.economist.com/world/asia/displaystory.cfm?story_id=12010369"CNN" informa: "Iraqi troops take control of key province": http://edition.cnn.com/2008/WORLD/meast/09/01/iraq.anbar.handover.coalition/index.htmlAFRICA"New York Times" informa: "Zimbabwe Lifts Ban on Aid Groups, but Its Effects Linger":http://www.nytimes.com/2008/08/30/world/africa/30zimbabwe.html?ref=world"CNN" publica: "Police seize opposition MPs in Zimbabwe": http://edition.cnn.com/2008/WORLD/africa/08/27/zimbabwe.arrests/index.html"El País" de Madrid anuncia: "Mauritania forma su primer Gobierno tras el golpe: El nuevo Ejecutivo está formado por 28 miembros, en su mayoría tecnócratas sin experiencia política": http://www.elpais.com/articulo/internacional/Mauritania/forma/primer/Gobierno/golpe/elpepuint/20080901elpepuint_8/Tes"CNN" informa: "Nigerian militants claim 29 soldiers dead; military disagrees": http://edition.cnn.com/2008/WORLD/africa/08/30/nigeria.attack/index.html"MSNBC" anuncia: "17 feared dead after aid plane crashes in Congo: No sign of survivors as humanitarian flight operated by U.S. firm goes down": http://www.msnbc.msn.com/id/26505815/"CNN" informa: "Sudan hijackers surrender":http://edition.cnn.com/2008/WORLD/africa/08/27/sudan.plane.hostages/index.htmlECONOMIA"The Economist" publica su informa semanal: "Business this week": http://www.economist.com/displaystory.cfm?story_id=12011210"CNN" anuncia: "Iraq signs $3 billion oil deal with China":http://edition.cnn.com/2008/BUSINESS/08/30/iraq.china.oil.deal/index.html"The Economist" informa: "The second browser war: Google's new web browser is its most direct attack on Microsoft yet": http://www.economist.com/opinion/displayStory.cfm?story_id=12039759&source=features_box_main"MSNBC" publica: "Oil industry tallies the damage from Gustav: Early indications that storm caused little damage to Gulf's facilities":http://www.msnbc.msn.com/id/26509771/"MSNBC" analiza: "The world's most powerful women: Business and political leaders on Forbes list control $26 trillion worldwide": http://www.msnbc.msn.com/id/26426065/"Time" publica: "Google Enters the Browser Wars": http://www.time.com/time/business/article/0,8599,1837914,00.html

© 2021 The Authors. ; Aims: Understanding fine-grain diversity patterns across large spatial extents is fundamental for macroecological research and biodiversity conservation. Using the GrassPlot database, we provide benchmarks of fine-grain richness values of Palaearctic open habitats for vascular plants, bryophytes, lichens and complete vegetation (i.e., the sum of the former three groups). Location: Palaearctic biogeographic realm. Methods: We used 126,524 plots of eight standard grain sizes from the GrassPlot database: 0.0001, 0.001, 0.01, 0.1, 1, 10, 100 and 1,000 m and calculated the mean richness and standard deviations, as well as maximum, minimum, median, and first and third quartiles for each combination of grain size, taxonomic group, biome, region, vegetation type and phytosociological class. Results: Patterns of plant diversity in vegetation types and biomes differ across grain sizes and taxonomic groups. Overall, secondary (mostly semi-natural) grasslands and natural grasslands are the richest vegetation type. The open-access file "GrassPlot Diversity Benchmarks" and the web tool "GrassPlot Diversity Explorer" are now available online (https://edgg.org/databases/GrasslandDiversityExplorer) and provide more insights into species richness patterns in the Palaearctic open habitats. Conclusions: The GrassPlot Diversity Benchmarks provide high-quality data on species richness in open habitat types across the Palaearctic. These benchmark data can be used in vegetation ecology, macroecology, biodiversity conservation and data quality checking. While the amount of data in the underlying GrassPlot database and their spatial coverage are smaller than in other extensive vegetation-plot databases, species recordings in GrassPlot are on average more complete, making it a valuable complementary data source in macroecology. ; GrassPlot development has been supported by the Bavarian Research Alliance (BayIntAn_UBT_2017_58), the Eurasian Dry Grassland Group (EDGG) and the International Association for Vegetation Science (IAVS); IB, CorM, JAC, IGM, DGM, MHe, DL and MTo were supported by the Basque Government (IT936‐16); CorM, IAx, MCh, JDa, PD, MHá, ZL, ZPr, EŠ and LT were supported by the Czech Science Foundation (19‐28491X); TR was supported by the Estonian Research Council (PUT1173); RJP was funded by the Strategic Research Programme of the Scottish Government's Rural and Environmental Science and Analytical Services Division"; SBa was supported by the GINOP‐2.3.2‐15‐2016‐00019 project; GFi was partially supported by the MIUR initiative "Department of excellence" (Law 232/2016)"; BJA was funded by the Spanish Research Agency (grant AEI/ 10.13039/501100011033); AK, VB, IM, DS, IV and DV were supported by the National Research Foundation of Ukraine (2020.01/0140); MP and AH were supported by the Estonian Research Council (PRG874, PRG609), and the European Regional Development Fund (Centre of Excellence EcolChange); Data collection of HCP was funded by FORMAS (Swedish Research Council for Environment, Agricultural Science and Spatial Planning) and The Swedish Institute; JR was supported by the Czech Science Foundation (grant No. 20‐09895S) and the long‐term developmental project of the Czech Academy of Sciences (RVO 67985939); ATRA was funded by the Grant of Excellence Departments, MIUR‐Italy (ARTICOLO 1, COMMI 314 – 337 LEGGE 232/2016); JMA was supported by Carl Tryggers stiftelse för vetenskaplig forskning and Qatar Petroleum; AAli was supported by the Jiangsu Science and Technology Special Project (Grant No. BX2019084), and Metasequoia Faculty Research Startup Funding at Nanjing Forestry University (Grant No. 163010230), and he is currently supported by Hebei University through Faculty Research Startup Funding Program; ZB was supported by the NKFI K 124796 grant; The GLORIA‐ Aragón project of JLBA was funded by the Dirección General de Cambio Climático del Gobierno de Aragón (Spain); MCs and LDem were supported by DG Environment through the European Forum on Nature Conservation and Pastoralism and Barbara Knowles Fund, in collaboration with Pogány‐havas Association, Romania; JDa was partially supported by long‐term research development project no. RVO 67985939 of the Czech Academy of Sciences; BD and OV were supported by the NKFI KH 126476, NKFI KH 130338, NKFI FK 124404 and NKFI FK 135329 grants; BD, OV and AKe were supported by the Bolyai János Scholarship of the Hungarian Academy of Sciences; BE was funded by the Environmental Department of the Tyrolean Federal State Government, the MAB Programme of the Austrian Academy of Science, the Mountain Agriculture Research Unit and the Alpine Research Centre Obergurgl of Innsbruck University. The GLORIA projects of BE were funded by the EU project no. EVK2‐CT‐2000‐00056, the Earth System Sciences Program of the Austrian Academy of Sciences (project MEDIALPS), the Amt für Naturparke, Autonome Provinz Bozen‐Südtirol, the Südtiroler Wissenschaftsfonds and the Tiroler Wissenschaftsfonds; RGG was supported by the Spanish Ministry of Research to sample GLORIA sites in central Spain (CGL 2008‐00901/BOS) and present works by the Autonomous Region of Madrid (REMEDINAL TE‐CM, S2018/EMT‐4338); MJ was supporteLatviaed by Latvia Grant No. 194051; NP and SŠ were partly supported by the Slovenian Research Agency, core fundings P1‐0403 and J7‐1822.

Green plants (Viridiplantae) include around 450,000-500,000 species(1,2) of great diversity and have important roles in terrestrial and aquatic ecosystems. Here, as part of the One Thousand Plant Transcriptomes Initiative, we sequenced the vegetative transcriptomes of 1,124 species that span the diversity of plants in a broad sense (Archaeplastida), including green plants (Viridiplantae), glaucophytes (Glaucophyta) and red algae (Rhodophyta). Our analysis provides a robust phylogenomic framework for examining the evolution of green plants. Most inferred species relationships are well supported across multiple species tree and supermatrix analyses, but discordance among plastid and nuclear gene trees at a few important nodes highlights the complexity of plant genome evolution, including polyploidy, periods of rapid speciation, and extinction. Incomplete sorting of ancestral variation, polyploidization and massive expansions of gene families punctuate the evolutionary history of green plants. Notably, we find that large expansions of gene families preceded the origins of green plants, land plants and vascular plants, whereas whole-genome duplications are inferred to have occurred repeatedly throughout the evolution of flowering plants and ferns. The increasing availability of high-quality plant genome sequences and advances in functional genomics are enabling research on genome evolution across the green tree of life. ; Alberta Ministry of Advanced Education; Alberta Innovates AITF/iCORE Strategic Chair [RES0010334]; Musea Ventures; National Key Research and Development Program of China [2016YFE0122000]; Ministry of Science and Technology of the People's Republic of ChinaMinistry of Science and Technology, China [2015BAD04B01/2015BAD04B03]; State Key Laboratory of Agricultural Genomics [2011DQ782025]; Guangdong Provincial Key Laboratory of core collection of crop genetic resources research and application [2011A091000047]; Shenzhen Municipal Government of China [CXZZ20140421112021913/JCYJ20150529150409546/JCYJ20150529150505656]; National Science FoundationNational Science Foundation (NSF) [DBI-1265383, IOS 0922742, IOS-1339156, DEB 0830009, EF-0629817, EF-1550838, DEB 0733029, DBI 1062335, 1461364]; National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [1R01DA025197]; Deutsche ForschungsgemeinschaftGerman Research Foundation (DFG) [Qu 141/5-1, Qu 141/6-1, GR 3526/7-1, GR 3526/8-1]; Natural Sciences and Engineering Research Council of CanadaNatural Sciences and Engineering Research Council of Canada ; The 1KP initiative was funded by the Alberta Ministry of Advanced Education and Alberta Innovates AITF/iCORE Strategic Chair (RES0010334) to G.K.-S.W., Musea Ventures, The National Key Research and Development Program of China (2016YFE0122000), The Ministry of Science and Technology of the People's Republic of China (2015BAD04B01/2015BAD04B03), the State Key Laboratory of Agricultural Genomics (2011DQ782025) and the Guangdong Provincial Key Laboratory of core collection of crop genetic resources research and application (2011A091000047). Sequencing activities at BGI were also supported by the Shenzhen Municipal Government of China (CXZZ20140421112021913/JCYJ20150529150409546/JCYJ20150529150505656). Computation support was provided by the China National GeneBank (CNGB), the Texas Advanced Computing Center (TACC), WestGrid and Compute Canada; considerable support, including personnel, computational resources and data hosting, was also provided by the iPlant Collaborative (CyVerse) funded by the National Science Foundation (DBI-1265383), National Science Foundation grants IOS 0922742 (to C.W.d., P.S.S., D.E.S. and J.H.L.-M.), IOS-1339156 (to M.S.B.), DEB 0830009 (to J.H.L.-M., C.W.d., S.W.G. and D.W.S.), EF-0629817 (to S.W.G. and D.W.S.), EF-1550838 (to M.S.B.), DEB 0733029 (to T.W. and J.H.L.-M.), and DBI 1062335 and 1461364 (to T.W.), a National Institutes of Health Grant 1R01DA025197 (to T.M.K., C.W.d. and J.H.L.-M.), Deutsche Forschungsgemeinschaft grants Qu 141/5-1, Qu 141/6-1, GR 3526/7-1, GR 3526/8-1 (to M.Q. and I.G.) and a Natural Sciences and Engineering Research Council of Canada Discovery grant (to S.W.G.). We thank all national, state, provincial and regional resource management authorities, including those of province Nord and province Sud of New Caledonia, for permitting collections of material for this research. ; Public domain authored by a U.S. government employee

We conducted preregistered replications of 28 classic and contemporary published findings, with protocols that were peer reviewed in advance, to examine variation in effect magnitudes across samples and settings. Each protocol was administered to approximately half of 125 samples that comprised 15,305 participants from 36 countries and territories. Using the conventional criterion of statistical significance (p < .05), we found that 15 (54%) of the replications provided evidence of a statistically significant effect in the same direction as the original finding. With a strict significance criterion (p < .0001), 14 (50%) of the replications still provided such evidence, a reflection of the extremely high-powered design. Seven (25%) of the replications yielded effect sizes larger than the original ones, and 21 (75%) yielded effect sizes smaller than the original ones. The median comparable Cohen's ds were 0.60 for the original findings and 0.15 for the replications. The effect sizes were small (< 0.20) in 16 of the replications (57%), and 9 effects (32%) were in the direction opposite the direction of the original effect. Across settings, the Q statistic indicated significant heterogeneity in 11 (39%) of the replication effects, and most of those were among the findings with the largest overall effect sizes; only 1 effect that was near zero in the aggregate showed significant heterogeneity according to this measure. Only 1 effect had a tau value greater than .20, an indication of moderate heterogeneity. Eight others had tau values near or slightly above .10, an indication of slight heterogeneity. Moderation tests indicated that very little heterogeneity was attributable to the order in which the tasks were performed or whether the tasks were administered in lab versus online. Exploratory comparisons revealed little heterogeneity between Western, educated, industrialized, rich, and democratic (WEIRD) cultures and less WEIRD cultures (i.e., cultures with relatively high and low WEIRDness scores, respectively). Cumulatively, variability in the observed effect sizes was attributable more to the effect being studied than to the sample or setting in which it was studied.

Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectrical impedance analysis, adjusted for sex, age, height, and fat mass. Twenty-one single-nucleotide polymorphisms were significantly associated with lean body mass either genome wide (p < 5 x 10(-8)) or suggestively genome wide (p < 2.3 x 10(-6)). Replication in 63,475 (47,227 of European ancestry) individuals from 33 cohorts for whole body lean body mass and in 45,090 (42,360 of European ancestry) subjects from 25 cohorts for appendicular lean body mass was successful for five single-nucleotide polymorphisms in/ near HSD17B11, VCAN, ADAMTSL3, IRS1, and FTO for total lean body mass and for three single-nucleotide polymorphisms in/ near VCAN, ADAMTSL3, and IRS1 for appendicular lean body mass. Our findings provide new insight into the genetics of lean body mass. ; NIH [N01 AG 12100, U01 HL72515, U01 GM074518, R01 HL088119, R01 AR046838, U01 HL084756, N01-AG-12100, U24AG051129]; NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association); Althingi (the Icelandic Parliament); Mid-Atlantic Nutrition and Obesity Research Center of Maryland [P30 DK072488]; NIH/NIAMS [F32AR059469]; American Heart Association [10SDG2690004]; NHLBI [N01-HC-85079, N01-HC-85080, N01-HC-85081, N01-HC-85082, N01-HC-85083, N01-HC-85084, N01-HC-85085, N01-HC-85086, N01-HC-35129, N01 HC-15103, N01 HC-55222, N01-HC-75150, N01-HC-45133, N01-HC-85239, HL080295, HL087652, HL105756, HL103612, HL120393, HL130114]; NINDS; NIA [AG-023629, AG-15928, AG-20098, AG-027058, 1R01AG032098-01A1]; National Center for Research Resources [UL1RR033176]; CTSI [UL1TR000124]; National Institute of Diabetes and Digestive and Kidney Disease grant [DK063491]; Southern California Diabetes Endocrinology Research Center; GlaxoSmithKline; Faculty of Biology and Medicine of Lausanne; Swiss National Science Foundation [33CSCO-122661, 33CS30-139468, 33CS30-148401]; deCODE Genetics, ehf; Cancer Research United Kingdom; Medical Research Council; EU [LSHM-CT-2003-503041]; Wellcome Trust [WT098051, WT089062, WT098017]; Netherlands Organisation for Scientific Research (NWO); Erasmus MC; Centre for Medical Systems Biology (CMSB); European Community's Seventh Framework Programme (FP7), ENGAGE Consortium [HEALTH-F4-2007-201413]; Wellcome Trust; Support for Science Funding programme; CamStrad; Danish Council for Independent Research [DFF-1333-00124, DFF-1331-00730B]; US National Institute for Arthritis, Musculoskeletal and Skin Diseases; National Institute on Aging [U24AG051129, R01 AR 41398, R01AR057118]; FP7-PEOPLE-Marie Curie Career Integration Grants (CIG); National Heart, Lung, and Blood Institute's Framingham Heart Study [N01-HC-25195]; Affymetrix, Inc. [N02-HL-6-4278]; Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine; Boston Medical Center; Genome Quebec; Genome Canada; Canadian Institutes of Health Research (CIHR); Swedish Research Council; Swedish Foundation for Strategic Research; ALF/LUA research grant in Gothenburg; Lundberg Foundation; Emil and Vera Cornell Foundation; Torsten and Ragnar Soderberg's Foundation; Petrus and Augusta Hedlunds Foundation; Vastra Gotaland Foundation; Goteborg Medical Society; German Bundesministerium fuer Forschung und Technology [01 AK 803 A-H, 01 IG 07015G]; National Institutes of Aging; National Institutes of Health [HHSN268200782096C, R01 AG 041517, M01 RR-00750]; Intramural Research Program of the NIH, National Library of Medicine. Kora; Helmholtz Center Munich, German Research Center for Environmental Health; German Federal Ministry of Education and Research (BMBF); State of Bavaria; German National Genome Research Network [NGFN-2, NGFNPlus: 01GS0823]; Munich Center of Health Sciences (MC Health) as part of LMUinnovativ; British Heart Foundation; Kidney Research UK; National Institute for Health Research (NIHR) programme grant; Netherlands Consortium for Healthy Aging (NCHA) [050-060-810]; Erasmus Medical Center; Erasmus University, Rotterdam; Netherlands Organization for the Health Research and Development (ZonMw); Research Institute for Diseases in the Elderly (RIDE); Ministry of Education, Culture and Science; Ministry for Health, Welfare and Sports; European Commission (DG XII); Municipality of Rotterdam; National Institute on Aging grants [R01AG17917, R01AG15819, R01AG24480]; Illinois Department of Public Health; Rush Clinical Translational Science Consortium; Arthritis Research UK; Chronic Disease Research Foundation; National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award; Israel Science Foundation [994/10]; NIA Intramural Research Program; Hjartavernd (the Icelandic Heart Association); German Federal Ministry of Education and Research (BMBF) [16SV5536K, 16SV5537, 16SV5538, 16SV5837, 01UW0808]; Max Planck Institute for Human Development (MPIB); Max Planck Institute for Molecular Genetics (MPIMG); Charite University Medicine; German Institute for Economic Research (DIW); University of Lubeck in Lubeck, Germany; Netherlands Organization for Health Research and Development (ZonMw) the Hague [6130.0031]; NZO (Dutch Dairy Association), Zoetermeer; Orthica, Almere; NCHA (Netherlands Consortium Healthy Ageing) Leiden/Rotterdam; Ministry of Economic Affairs, Agriculture and Innovation, the Hague [KB-15-004-003]; Wageningen University, Wageningen; VU University Medical Center, Amsterdam; Erasmus Medical Center, Rotterdam; Healthway Health Promotion Foundation of Western Australia; Australasian Menopause Society; Australian National Health and Medical Research Council [254627, 303169, 572604]; National Health and Medical Research Council of Australia Career Development Fellowship; Karen Elise Jensen foundation; NIH from NHLBI [R01-HL-117078, R01-HL-087700, R01-HL-088215]; NIH from NIDDK [R01-DK-089256, R01-DK-075681]; Academy of Finland Center of Excellence in Complex Disease Genetics [213506, 129680]; Academy of Finland [251217, 136895, 141005, 139635, 129494, 269517]; Finnish foundation for Cardiovascular Research; Sigrid Juselius Foundation; Yrjo Jahnsson Foundation; Finnish Diabetes Research Society; Samfundet Folkhalsann; Novo Nordisk Foundation; Liv och Halsa; Finska Lakaresallskapet; Signe and Ane Gyllenberg Foundation; University of Helsinki; European Science Foundation (EUROSTRESS); Ministry of Education; Ahokas Foundation; Emil Aaltonen Foundation; Juho Vainio Foundation; Centers for Disease Control and Prevention/Association of Schools of Public Health [S043, S1734, S3486]; NIAMS Multipurpose Arthritis and Musculoskeletal Disease Center grant [5-P60-AR30701]; NIAMS Multidisciplinary Clinical Research Center grant [5 P60 AR49465-03]; Research Program - Korea Centers for Disease Control and Prevention [2001-347-6111-221, 2002-347-6111-221, 2009-E71007-00, 2010-E71004-00]; Helmholtz Center Munich; German Research Center for Environmental Health; British Heart Foundation Grant [SP/04/002]; Academy of Finland; Finnish Diabetes Research Foundation; Finnish Cardiovascular Research Foundation; Strategic Research Funding from the University of Eastern Finland, Kuopio; EVO grant from the Kuopio University Hospital [5263]; Swedish Research Council [2006-3832, K2009-53X-14691-07-3, K2010-77PK-21362-01-2, 2008-2202, 2005-8214]; Greta and Johan Kock Foundation; A. Pahlsson Foundation; A. Osterlund Foundation; Malmo University Hospital Research Foundation; Research and Development Council of Region Skane, Sweden; Swedish Medical Society; National Institutes of Health; National Institute on Aging (NIA); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); National Center for Advancing Translational Sciences (NCATS); NIH Roadmap for Medical Research [U01 AG027810, U01 AG042124, U01 AG042139, U01 AG042140, U01 AG042143, U01 AG042145, U01 AG042168, U01 AR066160, UL1 TR000128]; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) [RC2ARO58973]; FAS [2007-2125]; Chief Scientist Office of the Scottish Government [CZB/4/276, CZB/4/710]; Royal Society; MRC Human Genetics Unit; Arthritis Research UK [17539]; European Union framework program 6 EUROSPAN project [LSHG-CT-2006-018947]; ALF/LUA research grants from Uppsala university hospital, Uppsala, Sweden; European Union Grant [QLG1-CT-2001-01252]; AstraZeneca; SHIP, part of the Community Medicine Research Network of the University of Greifswald, Germany; Federal Ministry of Education and Research [01ZZ9603, 01ZZ0103, 01ZZ0403]; Ministry of Cultural Affairs; Social Ministry of the Federal State of Mecklenburg-West Pomerania; network "Greifswald Approach to Individualized Medicine (GANI_MED)" - Federal Ministry of Education and Research [03IS2061A]; Siemens Healthcare, Erlangen, Germany; National Institute on Aging (NIA) [R01 AG005407, R01 AR35582, R01 AR35583, R01 AR35584, R01 AG005394, R01 AG027574, R01 AG027576]; Wallenberg foundation; Medical Research Council (UK); Republic of Croatia Ministry of Science, Education and Sports [108-1080315-0302]; National Heart, Lung, and Blood Institute, National Institutes of Health, US Department of Health and Human Services [N01WH22110, 24152, 32100-2, 32105-6, 32108-9, 32111-13, 32115, 32118-32119, 32122, 42107-26, 42129-32, 44221]; US National Institutes of Health grants [1-ZIA-HG000024, U01DK062370, R00DK099240]; American Diabetes Association Pathway to Stop Diabetes Grant [1-14-INI-07]; Academy of Finland Grants [271961, 272741, 258753]; Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA; National Heart Lung and Blood Institute of the National Institutes of Health [HL57453]; [HHSN268201200036C] ; This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.

Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectrical impedance analysis, adjusted for sex, age, height, and fat mass. Twenty-one single-nucleotide polymorphisms were significantly associated with lean body mass either genome wide (p < 5 × 10−8) or suggestively genome wide (p < 2.3 × 10−6). Replication in 63,475 (47,227 of European ancestry) individuals from 33 cohorts for whole body lean body mass and in 45,090 (42,360 of European ancestry) subjects from 25 cohorts for appendicular lean body mass was successful for five single-nucleotide polymorphisms in/near HSD17B11, VCAN, ADAMTSL3, IRS1, and FTO for total lean body mass and for three single-nucleotide polymorphisms in/near VCAN, ADAMTSL3, and IRS1 for appendicular lean body mass. Our findings provide new insight into the genetics of lean body mass. ; We acknowledge the essential role of the Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) Consortium in development and support of this manuscript. CHARGE members include the Netherland's Rotterdam Study (RS), Framingham Heart Study (FHS), Cardiovascular Health Study (CHS), the NHLBI's Atherosclerosis Risk in Communities (ARIC) Study, and Iceland's Age, Gene/Environment Susceptibility (AGES) Reykjavik Study. Age, Gene/Environment Susceptibility Reykjavik Study (AGES-Reykjavik): has been funded by NIH contract N01-AG-12100, the NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (the Icelandic Parliament). The study is approved by the Icelandic National Bioethics Committee, (VSN: 00-063) and the Data Protection Authority. The researchers are indebted to the participants for their willingness to participate in the study. Old Order Amish (OOA): this work was supported by NIH research grants U01 HL72515, U01 GM074518, R01 HL088119, R01 AR046838, and U01 HL084756. Partial funding was also provided by the Mid-Atlantic Nutrition and Obesity Research Center of Maryland (P30 DK072488).). L.M.Y.-A. was supported by F32AR059469 from NIH/NIAMS. M.F. was supported by American Heart Association grant 10SDG2690004. Cardiovascular Health Study (CHS): This CHS research was supported by NHLBI contracts N01-HC- 85079, N01-HC-85080, N01-HC-85081, N01-HC-85082, N01-HC-85083, N01-HC-85084, N01-HC-85085, N01-HC-85086; N01-HC-35129, N01 HC-15103, N01 HC-55222, N01-HC-75150, N01-HC-45133, N01-HC-85239, and by HHSN268201200036C and NHLBI grants HL080295, HL087652, HL105756, HL103612, HL120393, and HL130114 with additional contribution from NINDS. Additional support was provided through AG-023629, AG-15928, AG-20098, and AG-027058 from the NIA. See also http://www.chs-nhlbi.org/pi.htm. DNA handling and genotyping at Cedars-Sinai Medical Center was supported in part by the National Center for Research Resources, grant UL1RR033176, and is now at the National Center for Advancing Translational Sciences, CTSI grant UL1TR000124; in addition to the National Institute of Diabetes and Digestive and Kidney Disease grant DK063491 to the Southern California Diabetes Endocrinology Research Center. CoLaus: The CoLaus study received financial contributions from GlaxoSmithKline, the Faculty of Biology and Medicine of Lausanne, and the Swiss National Science Foundation (grants 33CSCO-122661, 33CS30-139468, and 33CS30-148401). We thank Vincent Mooser and Gérard Waeber, Co-PIs of the CoLaus study. Special thanks to Yolande Barreau, Mathieu Firmann, Vladimir Mayor, Anne-Lise Bastian, Binasa Ramic, Martine Moranville, Martine Baumer, Marcy Sagette, Jeanne Ecoffey, and Sylvie Mermoud for data collection. Data analysis was supervised by Sven Bergmann and Jacques S. Beckmann. The computations for this paper were performed in part at the Vital-IT Center for high-performance computing of the Swiss Institute of Bioinformatics. deCODE Study: The study was funded by deCODE Genetics, ehf. We thank all the participants of this study, the staff of deCODE Genetics core facilities and recruitment center and the densitometry clinic at the University Hospital for their important contributions to this work. The EPIC Study: The EPIC Obesity study is funded by Cancer Research United Kingdom and the Medical Research Council. I.B. acknowledges support from EU FP6 funding (contract no. LSHM-CT-2003-503041) and by the Wellcome Trust (WT098051). Erasmus Rucphen Family (ERF) Study: The study was supported by grants from The Netherlands Organisation for Scientific Research (NWO), Erasmus MC, the Centre for Medical Systems Biology (CMSB), and the European Community's Seventh Framework Programme (FP7/2007-2013), ENGAGE Consortium, grant agreement HEALTH-F4-2007-201413. We are grateful to all general practitioners for their contributions, to Petra Veraart for her help in genealogy, Jeannette Vergeer for the supervision of the laboratory work and Peter Snijders for his help in data collection. Fenland: The Fenland Study is funded by the Wellcome Trust and the Medical Research Council, as well as by the Support for Science Funding programme and CamStrad. We are grateful to all the volunteers for their time and help, and to the General Practitioners and practice staff for help with recruitment. We thank the Fenland Study co-ordination team and the Field Epidemiology team of the MRC Epidemiology Unit for recruitment and clinical testing. Tuomas O. Kilpeläinen was supported by the Danish Council for Independent Research (DFF—1333-00124 and Sapere Aude program grant DFF—1331-00730B). Framingham Osteoporosis Study (FOS)/Framingham Heart Study (FHS): The study was funded by grants from the US National Institute for Arthritis, Musculoskeletal and Skin Diseases and National Institute on Aging (R01 AR 41398 and U24AG051129; D.P.K. and R01AR057118; D.K. D.K. was also supported by FP7-PEOPLE-2012-Marie Curie Career Integration Grants (CIG)). The Framingham Heart Study of the National Heart, Lung, and Blood Institute of the National Institutes of Health and Boston University School of Medicine were supported by the National Heart, Lung, and Blood Institute's Framingham Heart Study (N01-HC-25195) and its contract with Affymetrix, Inc. for genotyping services (N02-HL-6-4278). Analyses reflect intellectual input and resource development from the Framingham Heart Study investigators participating in the SNP Health Association Resource (SHARe) project. A portion of this research was conducted using the Linux Cluster for Genetic Analysis (LinGA-II) funded by the Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center. eQTL HOb Study: The study was supported by Genome Quebec, Genome Canada and the Canadian Institutes of Health Research (CIHR). Gothenburg Osteoporosis and Obesity Determinants Study (GOOD): The study was funded by the Swedish Research Council, the Swedish Foundation for Strategic Research, The ALF/LUA research grant in Gothenburg, the Lundberg Foundation, the Emil and Vera Cornell Foundation, the Torsten and Ragnar Söderberg's Foundation, Petrus and Augusta Hedlunds Foundation, the Västra Götaland Foundation, and the Göteborg Medical Society. We would like to thank Dr Tobias A. Knoch, Luc V. de Zeeuw, Anis Abuseiris, and Rob de Graaf as well as their institutions the Erasmus Computing Grid, Rotterdam, The Netherlands, and especially the national German MediGRID and Services@MediGRID part of the German D-Grid, both funded by the German Bundesministerium fuer Forschung und Technology under grants #01 AK 803 A-H and # 01 IG 07015G for access to their grid resources. We also thank Karol Estrada, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands for advice regarding the grid resources. Health Aging and Body Composition Study (Health ABC): This study was funded by the National Institutes of Aging. This research was supported by NIA contracts N01AG62101, N01AG62103, and N01AG62106. The genome-wide association study was funded by NIA grant 1R01AG032098-01A1 to Wake Forest University Health Sciences and genotyping services were provided by the Center for Inherited Disease Research (CIDR). CIDR is fully funded through a federal contract from the National Institutes of Health to The Johns Hopkins University, contract number HHSN268200782096C. Indiana: We thank the individuals who participated in this study, as well as the study coordinators, without whom this work would not have been possible. This work was supported by National Institutes of Health grants R01 AG 041517 and M01 RR-00750. Genotyping services were provided by CIDR. CIDR is fully funded through a federal contract from the National Institutes of Health to The Johns Hopkins University, contract number HHSN268200782096C. This research was supported in part by the Intramural Research Program of the NIH, National Library of Medicine. Kora (KORA F3 and KORA F4): The KORA research platform was initiated and financed by the Helmholtz Center Munich, German Research Center for Environmental Health, which is funded by the German Federal Ministry of Education and Research (BMBF) and by the State of Bavaria. Part of this work was financed by the German National Genome Research Network (NGFN-2 and NGFNPlus: 01GS0823). Our research was supported within the Munich Center of Health Sciences (MC Health) as part of LMUinnovativ. The London Life Sciences Population (LOLIPOP): The study was funded by the British Heart Foundation, Wellcome Trust, the Medical Research Council, and Kidney Research UK. The study also receives support from a National Institute for Health Research (NIHR) programme grant. Rotterdam Study (RSI, RSII & RSIII): The generation and management of GWAS genotype data for the Rotterdam Study (RS I, RS II, RS III) was executed by the Human Genotyping Facility of the Genetic Laboratory of the Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. The GWAS datasets are supported by the Netherlands Organisation of Scientific Research NWO Investments (no. 175.010.2005.011, 911-03-012), the Genetic Laboratory of the Department of Internal Medicine, Erasmus MC, the Research Institute for Diseases in the Elderly (014-93-015; RIDE2), the Netherlands Genomics Initiative (NGI)/Netherlands Organisation for Scientific Research (NWO) Netherlands Consortium for Healthy Aging (NCHA), project no. 050-060-810. We thank Pascal Arp, Mila Jhamai, Marijn Verkerk, Lizbeth Herrera, Marjolein Peters, MSc, and Carolina Medina-Gomez, MSc, for their help in creating the GWAS database, and Karol Estrada, PhD, Yurii Aulchenko, PhD, and Carolina Medina-Gomez, PhD, for the creation and analysis of imputed data. The Rotterdam Study is funded by Erasmus Medical Center and Erasmus University, Rotterdam, Netherlands Organization for the Health Research and Development (ZonMw), the Research Institute for Diseases in the Elderly (RIDE), the Ministry of Education, Culture and Science, the Ministry for Health, Welfare and Sports, the European Commission (DG XII), and the Municipality of Rotterdam. We are grateful to the study participants, the staff from the Rotterdam Study and the participating general practitioners and pharmacists. We thank Dr Karol Estrada, Dr Fernando Rivadeneira, Dr Tobias A. Knoch, Anis Abuseiris, and Rob de Graaf (Erasmus MC Rotterdam, The Netherlands) for their help in creating GRIMP, and we thank BigGRID, MediGRID, and Services@MediGRID/D-Grid (funded by the German Bundesministerium fuer Forschung und Technology; grants 01 AK 803 A-H, 01 IG 07015G) for access to their grid computing resources. Rush Memory and Aging Project (MAP): The Memory and Aging Project was supported by National Institute on Aging grants R01AG17917, R01AG15819, and R01AG24480, the Illinois Department of Public Health, the Rush Clinical Translational Science Consortium, and a gift from Ms Marsha Dowd. TwinsUK (TUK): The study was funded by the Wellcome Trust, Arthritis Research UK, and the Chronic Disease Research Foundation. The study also received support from a National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London. We thank the staff and volunteers of the TwinsUK study. The study was also supported by Israel Science Foundation, grant number 994/10. Age, Gene/Environment Susceptibility Reykjavik Study (AGES-Reykjavik) has been funded by NIH contract N01-AG-12100, the NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (the Icelandic Parliament). The study is approved by the Icelandic National Bioethics Committee (VSN: 00-063) and the Data Protection Authority. The researchers are indebted to the participants for their willingness to participate in the study. Berlin Aging Study II (BASE-II) was supported by the German Federal Ministry of Education and Research (BMBF (grants #16SV5536K, #16SV5537, #16SV5538, and #16SV5837; previously #01UW0808)). Additional contributions (e.g., financial, equipment, logistics, personnel) are made from each of the other participating sites, i.e., the Max Planck Institute for Human Development (MPIB), Max Planck Institute for Molecular Genetics (MPIMG), Charite University Medicine, German Institute for Economic Research (DIW), all located in Berlin, Germany, and University of Lübeck in Lübeck, Germany. B-vitamins in the prevention of osteoporotic fractures (B-PROOF): B-PROOF is supported and funded by The Netherlands Organization for Health Research and Development (ZonMw, grant 6130.0031), the Hague; unrestricted grant from NZO (Dutch Dairy Association), Zoetermeer; Orthica, Almere; NCHA (Netherlands Consortium Healthy Ageing) Leiden/Rotterdam; Ministry of Economic Affairs, Agriculture and Innovation (project KB-15-004-003), the Hague; Wageningen University, Wageningen; VU University Medical Center, Amsterdam; Erasmus Medical Center, Rotterdam. All organizations are based in the Netherlands. We thank Dr Tobias A. Knoch, Anis Abuseiris, Karol Estrada, and Rob de Graaf as well as their institutions the Erasmus Grid Office, Erasmus MC Rotterdam, The Netherlands, and especially the national German MediGRID and Services@MediGRID part of the German D-Grid, both funded by the German Bundesministerium fuer Forschung und Technology (grants #01 AK 803 A-H and #01 IG 07015G) for access to their gird resources. Further, we gratefully thank all participants. Calcium Intake Fracture Outcome Study (CAIFOS): This study was funded by Healthway Health Promotion Foundation of Western Australia, Australasian Menopause Society and the Australian National Health and Medical Research Council Project Grants (254627, 303169, and 572604). We are grateful to the participants of the CAIFOS Study. The salary of Dr Lewis is supported by a National Health and Medical Research Council of Australia Career Development Fellowship. Danish Osteoporosis Study (DOPS): The study was supported by Karen Elise Jensen foundation. Family Heart Study (FamHS): The study was supported by NIH grants R01-HL-117078, R01-HL-087700, and R01-HL-088215 from NHLBI; and R01-DK-089256 and R01-DK-075681 from NIDDK. GenMets (Health 2000): S.R. was supported by the Academy of Finland Center of Excellence in Complex Disease Genetics (213506 and 129680), Academy of Finland (251217), the Finnish foundation for Cardiovascular Research and the Sigrid Juselius Foundation. S.M. was supported by grants #136895 and #141005, V.S. by grants #139635 and 129494, and M.P. by grant #269517 from the Academy of Finland and a grant from the Finnish Foundation for Cardiovascular Research. M.P. was supported by the Yrjö Jahnsson Foundation. Helsinki Birth Cohort Study (HBCS): We thank all study participants as well as everybody involved in the HBCS. HBCS has been supported by grants from the Academy of Finland, the Finnish Diabetes Research Society, Samfundet Folkhälsann, Novo Nordisk Foundation, Liv och Hälsa, Finska Läkaresällskapet, Signe and Ane Gyllenberg Foundation, University of Helsinki, European Science Foundation (EUROSTRESS), Ministry of Education, Ahokas Foundation, Emil Aaltonen Foundation, Juho Vainio Foundation, and Wellcome Trust (grant number WT089062). Johnston County Study: The Johnston County Osteoarthritis Project is supported in part by cooperative agreements S043, S1734, and S3486 from the Centers for Disease Control and Prevention/Association of Schools of Public Health; the NIAMS Multipurpose Arthritis and Musculoskeletal Disease Center grant 5-P60-AR30701; and the NIAMS Multidisciplinary Clinical Research Center grant 5 P60 AR49465-03. Genotyping services were provided by Algynomics company. Korean Genome Epidemiology Study (KoGES): Korean Genome Epidemiology Study (KoGES): This work was supported by the Research Program funded by the Korea Centers for Disease Control and Prevention (found 2001-347-6111-221, 2002-347-6111-221, 2009-E71007-00, 2010-E71004-00). Kora F3 and Kora F4: The KORA research platform was initiated and financed by the Helmholtz Center Munich, German Research Center for Environmental Health, which is funded by the German Federal Ministry of Education and Research (BMBF) and by the State of Bavaria. Part of this work was financed by the German National Genome Research Network (NGFN-2 and NGFNPlus: 01GS0823). Our research was supported within the Munich Center of Health Sciences (MC Health) as part of LMUinnovativ. LOLIP-REP-IA610: The study was supported by the Wellcome Trust. We thank the participants and research teams involved in LOLIPOP. LOLIP-REP-IA_I: The study was supported by the British Heart Foundation Grant SP/04/002. LOLIP-REP-IA_P: The study was supported by the British Heart Foundation Grant SP/04/002. METSIM: The study was supported by the Academy of Finland, the Finnish Diabetes Research Foundation, the Finnish Cardiovascular Research Foundation, the Strategic Research Funding from the University of Eastern Finland, Kuopio, and the EVO grant 5263 from the Kuopio University Hospital. MrOS Sweden: Financial support was received from the Swedish Research Council (2006-3832), the Swedish Foundation for Strategic Research, the ALF/LUA research grant in Gothenburg, the Lundberg Foundation, the Torsten and Ragnar Söderberg's Foundation, Petrus and Augusta Hedlunds Foundation, the Västra Götaland Foundation, the Göteborg Medical Society, and the Novo Nordisk foundation. Greta and Johan Kock Foundation, A. Påhlsson Foundation, A. Osterlund Foundation, Malmö University Hospital Research Foundation, Research and Development Council of Region Skåne, Sweden, the Swedish Medical Society. MrOS US: The Osteoporotic Fractures in Men (MrOS) Study is supported by National Institutes of Health funding. The following institutes provide support: the National Institute on Aging (NIA), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Center for Advancing Translational Sciences (NCATS), and NIH Roadmap for Medical Research under the following grant numbers: U01 AG027810, U01 AG042124, U01 AG042139, U01 AG042140, U01 AG042143, U01 AG042145, U01 AG042168, U01 AR066160, and UL1 TR000128. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) provided funding for the MrOS ancillary study "GWAS in MrOS and SOF" under the grant number RC2ARO58973. Osteoporosis Prospective Risk Assessment study (OPRA): This work was supported by grants from the Swedish Research Council (K2009-53X-14691-07-3, K2010-77PK-21362-01-2), FAS (grant 2007-2125), Greta and Johan Kock Foundation, A. Påhlsson Foundation, A. Osterlund Foundation, Malmö University Hospital Research Foundation, Research and Development Council of Region Skåne, Sweden, the Swedish Medical Society. We are thankful to all the women who kindly participated in the study and to the staff at the Clinical and Molecular Osteoporosis Research Unit for helping in recruitment of study individuals. Orkney Complex Disease Study (ORCADES): ORCADES was supported by the Chief Scientist Office of the Scottish Government (CZB/4/276, CZB/4/710), the Royal Society, the MRC Human Genetics Unit, Arthritis Research UK (17539) and the European Union framework program 6 EUROSPAN project (contract no. LSHG-CT-2006-018947). DNA extractions were performed at the Wellcome Trust Clinical Research Facility in Edinburgh. We acknowledge the invaluable contributions of Lorraine Anderson and the research nurses in Orkney, the administrative team in Edinburgh and the people of Orkney. PEAK 25: This work was supported by grants from the Swedish Research Council (K2009-53X-14691-07-3, K2010-77PK-21362-01-2), FAS (grant 2007-2125), Greta and Johan Kock Foundation, A. Påhlsson Foundation, A. Osterlund Foundation, Malmö University Hospital Research Foundation, Research and Development Council of Region Skåne, Sweden, the Swedish Medical Society. We are thankful to all the women who kindly participated in the study and to the staff at the Clinical and Molecular Osteoporosis Research Unit for helping in recruitment of study individuals. Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS): The study was supported by grants from the Swedish research council (projects 2008-2202 and 2005-8214) and ALF/LUA research grants from Uppsala university hospital, Uppsala, Sweden. Relationship between Insulin Sensitivity and Cardiovascular Disease (RISC): The RISC study is supported by European Union Grant QLG1-CT-2001-01252 and AstraZeneca. We thank Merck Research Labs for conducting DNA genotyping on RISC samples.Rotterdam III: Rotterdam Study (RS): See discovery. SHIP and SHIP TREND: This work was supported by SHIP, which is part of the Community Medicine Research Network of the University of Greifswald, Germany, by the Federal Ministry of Education and Research (01ZZ9603, 01ZZ0103, and 01ZZ0403), the Ministry of Cultural Affairs as well as the Social Ministry of the Federal State of Mecklenburg-West Pomerania and the network "Greifswald Approach to Individualized Medicine (GANI_MED)" funded by the Federal Ministry of Education and Research (03IS2061A). Genome-wide data have been supported by the Federal Ministry of Education and Research (03ZIK012) and a joint grant from Siemens Healthcare, Erlangen, Germany, and the Federal State of Mecklenburg-West Pomerania. The University of Greifswald is a member of the "Center of Knowledge Interchange" program of the Siemens. A.G. and the Cache´ Campus program of the InterSystems GmbH. The SHIP authors are grateful to the contribution of Florian Ernst, Anja Wiechert, and Astrid Petersmann in generating the SNP data and to Mario Stanke for the opportunity to use his Server Cluster for SNP Imputation. Data analyses were further supported by the German Research Foundation (DFG Vo 955/10-1) and the Federal Ministry of Nutrition, Agriculture and Consumer's Safety. SOF: The Study of Osteoporotic Fractures (SOF) is supported by National Institutes of Health funding. The National Institute on Aging (NIA) provides support under the following grant numbers: R01 AG005407, R01 AR35582, R01 AR35583, R01 AR35584, R01 AG005394, R01 AG027574, and R01 AG027576. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) provided funding for the SOF ancillary study "GWAS in MrOS and SOF" under the grant number RC2ARO58973. Uppsala Longitudinal Study of Adult Men (ULSAM): The study was funded by grants from the Swedish research council (projects 2008-2202 and 2005-8214), the Wallenberg foundation, and ALF/LUA research grants from Uppsala university hospital, Uppsala, Sweden. Andrew P. Morris is a Wellcome Trust Senior Fellow in Basic Biomedical Science, grant number WT098017. CROATIA-VIS (VIS): The CROATIA-Vis study was funded by grants from the Medical Research Council (UK) and Republic of Croatia Ministry of Science, Education and Sports research grants to I.R. (108-1080315-0302). We acknowledge the staff of several institutions in Croatia that supported the field work, including but not limited to The University of Split and Zagreb Medical Schools, the Institute for Anthropological Research in Zagreb and Croatian Institute for Public Health. The SNP genotyping for the CROATIA-Vis cohort was performed in the core genotyping laboratory of the Wellcome Trust Clinical Research Facility at the Western General Hospital, Edinburgh, Scotland. Women's Health Initiative (WHI): The WHI program is funded by the National Heart, Lung, and Blood Institute, National Institutes of Health, US Department of Health and Human Services through contracts N01WH22110, 24152, 32100–2, 32105–6, 32108–9, 32111–13, 32115, 32118–32119, 32122, 42107–26, 42129–32, and 44221. We thank the WHI investigators and staff for their dedication, and the study participants for making the program possible. A listing of WHI investigators can be found at https://www.whi.org/researchers/Documents%20%20Write%20a%20Paper/WHI%20Investigator%20Short%20List.pdf. FUSION: This research was supported in part by US National Institutes of Health grants 1-ZIA-HG000024 (to F.S.C.), U01DK062370 (to M.B.), R00DK099240 (to S.C.J.P.), the American Diabetes Association Pathway to Stop Diabetes Grant 1-14-INI-07 (to S.C.J.P.), and Academy of Finland Grants 271961 and 272741 (to M.L.) and 258753 (to H.A.K.). We thank all the subjects for participation and the study personnel for excellent technical assistance. The Pima Indian Study: This study was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA. Studies of a Targeted Risk Reduction Intervention with Defined Exercise (STRRIDE): This study was supported by the National Heart Lung and Blood Institute of the National Institutes of Health, HL57453 (WEK). Gene expression in old and young muscle biopsies: S.M. and T.G. were supported in part by NIH U24AG051129. ; Peer Reviewed

El huracán Ike dejó al menos 64 muertos y miles de damnificados en Haití, cuya fuerza al golpear la isla de La Española fue de 4 en la escala Saffir-Simpson (de un máximo de 5). Con este balance, se eleva a más de 600 el número de víctimas fatales que han provocado entre los cuatro fenómenos, Fay, Hanna, Gustav y Ike en las últimas semanas. En la vecina República Dominicana, Ike obligó a la evacuación de 44 mil personas. Ike avanzaba este lunes frente a la costa sureste de Cuba con categoría 2 y vientos máximos sostenidos de 170 kilómetros por hora. Ante la alarma que han traído sus vientos y sus olas de siete metros, las autoridades cubanas han ordenado la evacuación de un millón de personas, el 10% de la población total del país. "El País" de Madrid: "Ike amenaza Haití, República Dominicana y Cuba convertido en un peligroso huracán: La región, en alerta máxima, ha iniciado evacuaciones preventivas.- Hanna provoca inundaciones en el sureste de EE UU y el área metropolitana de Washington": http://www.elpais.com/articulo/internacional/Ike/avanza/Bahamas/convertido/peligroso/huracan/categoria/elpepuint/20080906elpepuint_5/Tes "El huracán Ike obliga a evacuar los cayos de Florida tras golpear Cuba: El ciclón avanza hoy frente a la costa sureste de la isla caribeña con categoría 2. -Ha dejado 64 muertos en Haití": http://www.elpais.com/articulo/internacional/huracan/Ike/obliga/evacuar/cayos/Florida/golpear/Cuba/elpepuint/20080908elpepuint_4/Tes "Cuba rechaza la ayuda de EE UU por los destrozos del huracán Gustav": http://www.elpais.com/articulo/internacional/Cuba/rechaza/ayuda/EE/UU/destrozos/huracan/Gustav/elpepuintlat/20080907elpepuint_2/Tes "CNN": "Ike roars over Cuba; 900,000 evacuated": http://edition.cnn.com/2008/US/weather/09/08/hurricane.ike/index.html "Ike's floods kill dozens, cut off aid to parts of Haiti": http://edition.cnn.com/2008/WORLD/weather/09/07/ike.haiti.ap/index.html "Ike looms as Haiti counts the dead from 3 storms": http://edition.cnn.com/2008/WORLD/americas/09/06/Haiti.floods.ap/index.html "CNN" publica sitio con links relacionados a la temática: "Hurricanes and Cyclones": http://topics.cnn.com/topics/hurricanes_and_cyclones "La Nación": "El huracán Ike golpea a Cuba: Afecta a las provincias orientales y centrales con vientos máximos sostenidos de 160 kilómetros por hora; inundaciones, evacuados y destrozos": http://www.lanacion.com.ar/nota.asp?nota_id=1047744 "Máxima alerta en Cuba por la llegada del huracán Ike: El ciclón se dirigía anoche hacia la isla; miles de personas fueron evacuadas": http://www.lanacion.com.ar/nota.asp?nota_id=1047645 "BBC": "Cuba hammered by Hurricane Ike": http://news.bbc.co.uk/2/hi/americas/7603319.stm "China Daily": "Hurricane Ike weakens to Category 2 over Cuba": http://www.chinadaily.com.cn/world/2008-09/08/content_7008890.htm "Times": "Four killed as Hurricane Ike rakes Cuba": http://www.timesonline.co.uk/tol/news/world/us_and_americas/article4715379.ece "El Universal": "Abandona Ike Cuba, se dirige al Golfo de México": http://www.eluniversal.com.mx/notas/536977.html "Time": "Haiti Gets No Mercy from Hanna, Ike": http://www.time.com/time/world/article/0,8599,1839710,00.html "El Tiempo": "La Habana se salvó, pero los daños son enormes en Cuba tras el paso del huracán 'Ike'": http://www.eltiempo.com/mundo/latinoamerica/home/la-habana-se-salvo-pero-los-danos-son-enormes-en-cuba-tras-el-paso-del-huracan-ike_4519836-1 "El huracán 'Ike' deja cuatro muertos y grandes destrozos en el oriente y centro en Cuba: Con ráfagas de viento de hasta 261 kilómetros se abatió este lunes sobre la isla, lo que obligó a la evacuación de más de un millón de personas. Petroleras del Golfo de México toman medidas.": http://www.eltiempo.com/mundo/latinoamerica/relaciones/el-huracan-ike-deja-cuatro-muertos-y-grandes-destrozos-en-el-oriente-y-centro-en-cuba_4519213-1 "Embates de 'Ike' someten a La Habana a un "estadio de sitio"": http://www.eltiempo.com/mundo/latinoamerica/relaciones/embates-de-ike-someten-a-la-habana-a-un-estadio-de-sitio_4519787-1 AMERICA LATINA El pasado Domingo 7 de setiembre, Cristina Kirchner participó junto a Lula de los actos por la independencia de Brasil. La jefa de Estado asiste como "huésped de honor" de Lula a los desfiles militares. Luego de la reunión de los mandatarios, en el Palacio del Planalto, se reunieron para firmar acuerdos comerciales y de cooperación. Llegaron a un acuerdo sobre términos de intercambio en lo que respecta al comercio bilateral: los brasileños podrán utilizar el real y los argentinos el peso, en las importaciones y exportaciones. "La Nación" informa: "Afirmó Lula que el comercio bilateral sin dólares es un avance hacia la integración monetaria regional: El brasileño celebró el acuerdo firmado para que el intercambio entre ambos países se haga en pesos y reales; "es el paso inicial", afirmó; Cristina defendió el modelo económico y abogó por la llegada de capitales del país vecino": http://www.lanacion.com.ar/nota.asp?nota_id=1047751 "JB" anuncia: "Brasil e Argentina farão trocas comerciais em moeda local": http://jbonline.terra.com.br/extra/2008/09/08/e080910876.html "Globo" publica: "Brasil e Argentina assinam convênio para comércio em moeda local": http://oglobo.globo.com/economia/mat/2008/09/08/brasil_argentina_assinam_convenio_para_comercio_em_moeda_local-548127507.asp "El País" de Madrid analiza: "La cuerda floja de las remesas: El dinero de los emigrantes bolivianos supera la inversión extranjera, espantada por la caótica situación, y puede hacer peligrar el crecimiento económico": http://www.elpais.com/articulo/internacional/cuerda/floja/remesas/elpepuint/20080908elpepuint_3/Tes "La Nación" informa: "Golpe a una de las mayores organizaciones: Detienen al jefe de un cartel mexicano. Se trata de Alberto "El Tony" Sánchez Hinojosa y se sospecha que controlaba las operaciones del Cartel del Golfo; está acusado de secuestrar y extorsionar a empresarios y policías en Tabasco, en el sudeste de ese país": http://www.lanacion.com.ar/nota.asp?nota_id=1047823 "Time" informa: "Behind Mexico's Wave of Beheadings": http://www.time.com/time/world/article/0,8599,1839576,00.html "CNN" publica: "Russia, Venezuela may hold joint naval maneuvers": http://edition.cnn.com/2008/WORLD/europe/09/08/russia.venezuela.ap/index.html "Time" anuncia: "Russia to Send Ships, Planes to Venezuela": http://www.time.com/time/world/article/0,8599,1839692,00.html "CNN" infroma: "Police seize 2.75 tons of cocaine in Peru": http://edition.cnn.com/2008/WORLD/americas/09/08/peru.drugs.ap/index.html "La Nación" anuncia: "Prepara Brasil un plan para fortalecer el sector de defensa": http://www.lanacion.com.ar/nota.asp?nota_id=1047647 "El Tiempo" de Colombia informa: "Ingrid Betancourt gana Premio Príncipe de Asturias de la Concordia 2008; se lo dedica a secuestrados": http://www.eltiempo.com/mundo/europa/home/ngrid-betancourt-gana-premio-principe-de-asturias-de-la-concordia-2008-se-lo-dedica-a-secuestrados_4521623-1 "El Universal" de México publica: "Reclama Betancourt reconocimiento a víctimas de terrorismo: La ex candidata presidencial colombiana hizo pública esa petición durante su intervención en la primera reunión mundial de víctimas del terrorismo convocada por el secretario general de la ONU": http://www.eluniversal.com.mx/notas/536851.html ESTADOS UNIDOS / CANADA "El País" de Madrid informa: "El primer ministro de Canadá convoca a elecciones anticipadas para el 14 de octubre: El primer ministro Stephen Harper busca afianzar su poder.- Serán los terceros comicios en el país en cuatro años": http://www.elpais.com/articulo/internacional/primer/ministro/Canada/convoca/elecciones/anticipadas/octubre/elpepuint/20080907elpepuint_5/Tes Fannie Mae y Freddie Mac son compañías que cotizan en la Bolsa estadounidense y que están patrocinadas por el Congreso para brindar financiamiento en el mercado de la vivienda. Los gigantes hipotecarios, cuyas acciones perdieron casi la mitad de su valor en la bolsa de Nueva York, se encuentran en el corazón del mercado de la vivienda de Estados Unidos. Ellas garantizan o son dueñas del cerca de la mitad del mercado hipotecario de EE.UU., que en total asciende a US$12 billones. El pasado Domingo, en la mayor operación de rescate financiero de la historia del país, el gobierno de Estados Unidos asumió el control directo de los gigantes hipotecarios Fannie Mae y Freddie Mac, y destinó hasta 100.000 millones de dólares a cada una, con el fin de estabilizar el mercado inmobiliario que amenaza con colapsar la economía del país. Varios Medios informan: "El Mercurio" de Chile: "Monto de US$ 200 mil millones es el más grande rescate federal hecho por el país del norte: EE.UU. activa histórico plan de salvataje para las dos mayores hipotecarias": http://diario.elmercurio.com/2008/09/08/_portada/_portada/noticias/91BD8ACD-123B-43D2-B988-88E9FBE6C2DC.htm?id={91BD8ACD-123B-43D2-B988-88E9FBE6C2DC} "CNN": "U.S. seizes Fannie and Freddie: Treasury chief Paulson unveils historic government takeover of twin mortgage buyers. Top executives are out.": http://money.cnn.com/2008/09/07/news/companies/fannie_freddie/index.htm?cnn=yes "China Daily": "Fannie and Freddie shares dive, debt rallies": http://www.chinadaily.com.cn/world/2008-09/08/content_7009080.htm "El País" de Madrid: "EE UU inyectará hasta 140.000 millones para salvar a las hipotecarias: Bush evita la quiebra de Freddie y Fannie, que controlan la mitad del mercado": http://www.elpais.com/articulo/economia/EE/UU/inyectara/140000/millones/salvar/hipotecarias/elpepueco/20080908elpepieco_4/Tes "La Nación": "Gigantesco rescate financiero en EE.UU.: El gobierno asumió el control de las empresas hipotecarios Fannie Mae y Freddie Mac; para Bush, suponían un "riesgo inaceptable"": http://www.lanacion.com.ar/nota.asp?nota_id=1047689 Continua la carrera a la Casa Blanca: "El País" de Madrid informa: "El 'efecto Palin' catapulta a McCain en las encuestas: Un sondeo de Gallup sitúa al candidato republicano cuatro puntos por delante de Obama": http://www.elpais.com/articulo/internacional/efecto/Palin/catapulta/McCain/encuestas/elpepuint/20080908elpepuint_6/Tes "Le Monde" anuncia: "John McCain repasse devant Barack Obama selon un nouveau sondage": http://www.lemonde.fr/elections-americaines/article/2008/09/08/john-mccain-repasse-devant-barack-obama-selon-un-nouveau-sondage_1092555_829254.html#ens_id=1089564 "La Nación" publica: "McCain supera a Obama por primera vez: Según la última encuesta difundida, el candidato republicano obtendría una ventaja de cuatro puntos": http://www.lanacion.com.ar/nota.asp?nota_id=1047746 "BBC" anuncia: "White House race enters high gear The US presidential rivals have begun campaigning in earnest, as a new opinion poll put Republican John McCain ahead of Democrat Barack Obama": http://news.bbc.co.uk/2/hi/americas/7604333.stm "Time" publica sitio con links a artículos relacionados con las elecciones estadounidenses: http://thepage.time.com/ MOISÉS NAÍM analiza para "El País" de Madrid: "La carrera hacia la Casa Blanca: La telenovela más importante del mundo": http://www.elpais.com/articulo/internacional/telenovela/importante/mundo/elppgl/20080907elpepiint_2/Tes EUROPA "El País" de Madrid informa: "Los socialdemócratas de Alemania nominan al ministro de Exteriores como candidato a canciller: Frank-Walter Steinmeier enfrentará a Ángela Merkel en las elecciones del próximo año.- Kurt Beck renunciará como presidente del Partido Socialdemócrata (SPD)": http://www.elpais.com/articulo/internacional/socialdemocratas/Alemania/nominan/ministro/Exteriores/candidato/canciller/elpepuint/20080907elpepuint_6/Tes "El País" de Madrid publica: "El SPD elige a Steinmeier para competir con Merkel en 2009: El vicecanciller liderará a los socialdemócratas en Alemania": http://www.elpais.com/articulo/internacional/SPD/elige/Steinmeier/competir/Merkel/2009/elpepuint/20080908elpepiint_7/Tes "Le Monde" anuncia: "M. Steinmeier sera le candidat du SPD à la Chancellerie contre Mme Merkel": http://www.lemonde.fr/europe/article/2008/09/08/m-steinmeier-candidat-a-la-chancellerie-contre-mme-merkel_1092518_3214.html#ens_id=1059312 "La Nación" publica: "España: otra noche de incidentes con inmigrantes: Cuatro personas fueron detenidas a raíz de un nuevo enfrentamiento con la Guardia Civil durante una protesta por la muerte de un senegalés": http://www.lanacion.com.ar/nota.asp?nota_id=1047797 "Times" informa: "Gordon Brown to invite Gaddafi to London": http://www.timesonline.co.uk/tol/news/politics/article4712488.ece "El País" de Madrid informa: "Brown reúne a su Gabinete para relanzar su discutido liderazgo: El primer ministro británico ha convocado a sus ministros en Birmingham, donde la crisis económica será el asunto prioritario": http://www.elpais.com/articulo/internacional/Brown/reune/Gabinete/relanzar/discutido/liderazgo/elpepuint/20080908elpepuint_9/Tes "El País" de Madrid anuncia: "La UE reconoce a Ucrania como país europeo: Bruselas ofrece a Kiev un Acuerdo de Asociación que no cierra ninguna puerta": http://www.elpais.com/articulo/internacional/UE/reconoce/Ucrania/pais/europeo/elpepuint/20080909elpepuint_18/Tes "Times" anuncia: "European Union fails to offer Ukraine membership": http://www.timesonline.co.uk/tol/news/world/europe/article4719154.ece Continua el conflicto del Cáucaso: "El Tiempo" de Colombia anuncia: "Rusia amenaza bases de E.U. en Europa del Este y crece tensión en Georgia": http://www.eltiempo.com/mundo/europa/home/rusia-amenaza-bases-de-eu-en-europa-del-este-y-crece-tension-en-georgia_4521659-1 "New York Times" publica: "Russia's Recognition of Georgian Areas Raises Hopes of Its Own Separatists": http://www.nytimes.com/2008/09/10/world/europe/10separatists.html?ref=world "El País" de Madrid informa: "Rusia mantendrá 7.600 soldados en Osetia del Sur y Abajazia: Moscú establece relaciones diplomáticas con los dos territorios independentistas y anuncia que firmará tratados de ayuda militar": http://www.elpais.com/articulo/internacional/Rusia/mantendra/7600/soldados/Osetia/Sur/Abajazia/elpepuint/20080909elpepuint_15/Tes "El País" de Madrid informa: "Rusia retirará en un mes sus tropas de Georgia: Medvédev y los dirigentes europeos, encabezados por Sarkozy, confirman que unos 200 observadores civiles visitarán la zona de conflicto": http://www.elpais.com/articulo/internacional/Rusia/retirara/mes/tropas/Georgia/elpepuint/20080908elpepuint_8/Tes "Le Monde" publica: "Moscou accepte une mission de l'UE aux compétences limitées": http://www.lemonde.fr/europe/article/2008/09/08/la-russie-s-oppose-au-deploiement-d-une-mission-de-l-ue-en-georgie_1092878_3214.html#ens_id=1036786 "CNN" informa: "Russia agrees Georgia withdrawal deadline": http://edition.cnn.com/2008/WORLD/europe/09/08/russia.georgia.eu.sarkozy/index.html "BBC" anuncia: "Russians 'agree Georgia deadline'": http://news.bbc.co.uk/2/hi/europe/7604376.stm "China Daily" publica: "Medvedev: Russia ready for Georgia buffer pullout": http://www.chinadaily.com.cn/world/2008-09/08/content_7009103.htm ASIA – PACÍFICO /MEDIO ORIENTE El viudo de la asesinada Benazir Bhutto, Asif Alí Zardari, ha conseguido auparse a la Presidencia de Pakistán y suceder a Perez Musharraf (quien dimitió el pasado 18 de agosto para evitarse un proceso de destitución) al imponerse con una clara mayoría en una votación parlamentaria. El copresidente del gubernamental Partido Popular de Pakistán (PPP) ha jurado defender la Constitución del país en un acto que se ha desarrollado en inglés. "Que Alá me ayude y me guíe", ha pronunciado el presidente al finalizar de su jura. Varios medios informan al respecto: "Times": "Asif Ali Zardari sworn in as Pakistani President": http://www.timesonline.co.uk/tol/news/world/asia/article4714467.ece "Time": "Pakistan's Unlikely President": http://www.time.com/time/world/article/0,8599,1839935,00.html "El Universal" de México: "Jura viudo de Benazir Bhutto como presidente de Paquistán: Asif Ali Zardari ya es oficialmente presidente paquistaní tras una ceremonia realizada en el Palacio Presidencial de Islamabad, el mandatario de Afganistán presenció el evento": http://www.eluniversal.com.mx/notas/536756.html "El Tiempo" de Colombia: "Nuevo presidente de Pakistán, Asif Alí Zardari, asume el poder en un país en pleno caos": http://www.eltiempo.com/mundo/otrasregiones/home/nuevo-presidente-de-pakistan-asif-ali-zardari-asume-el-poder-en-un-pais-en-pleno-caos_4519323-1 "New York Times": "Widower of Bhutto Takes Office in Pakistan": http://www.nytimes.com/2008/09/10/world/asia/10pstan.html?ref=world Corea del Norte ha celebrado el pasado martes su 60 aniversario con múltiples eventos entre los que ha destacado un multitudinario desfile militar, el mayor de su historia, según funcionarios del Gobierno. Corea del Norte cumple 60 años sumida en la hambruna, crisis del proceso de desnuclearización, y ante la incógnita sobre la salud de su líder, Kim Jong-il, quién lleva semanas sin ser visto en público. La salud del máximo mandatario norcoreano, que oficialmente desempeña sólo el cargo de presidente de la Comisión de Defensa Nacional, está íntimamente relacionado con el destino de Corea del Norte, ya que Kim heredó el liderazgo del régimen comunista de su padre, Kim Il-sung. Varios medios informan al respecto: "CNN": "North Korea prepares for 60th anniversary": http://edition.cnn.com/2008/WORLD/asiapcf/09/08/north.korea.60th.anniversary.ap/index.html "Los Angeles Times": "North Korea's Kim Jong Il may be gravely ill": http://www.latimes.com/news/nationworld/world/la-fg-kim10-2008sep10,0,7264304.story "Times": "Has anyone seen the Dear Leader Kim Jong Il?": http://www.timesonline.co.uk/tol/news/world/asia/article4720013.ece "El Universal" de México: "Celebra Corea del Norte 60 años en crisis de hambruna: al menos 60 millones de dólares en los próximos tres meses evitarían que se derive una hambruna generalizada, alerta Programa Mundial de Alimentos": http://www.eluniversal.com.mx/notas/536527.html "Time": "Officials: N Korea's Kim Possibly Ill": http://www.time.com/time/world/article/0,8599,1839884,00.html "New York Times": "Kim Had Surgery After Stroke, South Koreans Say": http://www.nytimes.com/2008/09/11/world/asia/11korea.html?ref=world "El País" de Madrid analiza: "Afganistán se hunde en el caos: El elevado número de víctimas civiles de las fuerzas internacionales y la falta de desarrollo del país dificultan la lucha contra los talibanes": http://www.elpais.com/articulo/internacional/Afganistan/hunde/caos/elpepuint/20080907elpepiint_3/Tes "Le Monde" anuncia: "L'Inde obtient un feu vert international pour importer de la technologie nucléaire": http://www.lemonde.fr/asie-pacifique/article/2008/09/08/l-inde-obtient-un-feu-vert-international-pour-importer-de-la-technologie-nucleaire_1092682_3216.html#ens_id=1077533 "CNN" publica: "Israeli police recommend charges for PM Olmert": http://edition.cnn.com/2008/WORLD/meast/09/07/olmert/index.html "New York Times" publica: "Earthquake Shakes Southern Iran": http://www.nytimes.com/2008/09/11/world/middleeast/11iran.html?ref=world "CNN" informa: "Iran calls for oil output cut ahead of OPEC meeting": http://edition.cnn.com/2008/BUSINESS/09/08/opec.meeting.ap/index.html "China Daily" analiza: "Commerce minister: China to top Asian consumer markets in 2009": http://www.chinadaily.com.cn/china/2008-09/08/content_7008871.htm "Times" anuncia: " Hundreds missing in Chinese landslide": http://www.timesonline.co.uk/tol/news/world/asia/article4715978.ece AFRICA "CNN" publica: "Death toll from Egypt rockslide reaches 47, expected to climb": http://edition.cnn.com/2008/WORLD/africa/09/08/egypt.rockslide.ap/index.html "BBC" anuncia: "Cairo rockslide death toll climbs": http://news.bbc.co.uk/2/hi/middle_east/7603690.stm "Le Monde" informa sobre elecciones en Angola: "Le parti au pouvoir en Angola se dirige vers une large victoire aux élections législatives": http://www.lemonde.fr/afrique/article/2008/09/07/le-parti-au-pouvoir-se-dirige-vers-une-large-victoire-aux-elections-legislatives_1092437_3212.html#ens_id=1088606 "CNN" publica: "EU: Historic Angolan election 'a disaster'": http://edition.cnn.com/2008/WORLD/africa/09/05/angola.elections.ap/index.html "BBC" informa sobre situación política en Zimbabwe: "Mbeki bids to save Zimbabwe talks": http://news.bbc.co.uk/2/hi/africa/7603532.stm "Los Angeles Times" publica: "Zimbabwe bloggers shine a light on their troubled country": http://www.latimes.com/news/nationworld/world/la-fg-zimblogs10-2008sep10,0,1482204.story "CNN" anuncia: "Mbeki tries to resolve Zimbabwe political deadlock": http://edition.cnn.com/2008/WORLD/africa/09/08/zimbabwe.mbeki.talks.ap/index.html "CNN" informa sobre visita de Condolezza al continente africano: "Rice meets with Libya leader": http://edition.cnn.com/2008/WORLD/africa/09/05/libya.us/index.html ECONOMIA "The Economist" publica su informe semanal: "Business this week": http://www.economist.com/displaystory.cfm?story_id=12073648 "CNN" informa: "Oil flat as mortgage rescue boosts dollar: Investors also worry about slumping global demand ahead of the OPEC meeting and eye Hurricane Ike's threat to Gulf of Mexico production.": http://money.cnn.com/2008/09/08/markets/oil/index.htm?cnn=yes "Times" publica: "Oil falls below $100 a barrel ahead of Opec meeting": http://business.timesonline.co.uk/tol/business/industry_sectors/natural_resources/article4714253.ece "Miami Herald" anuncia: "Oil prices slip even after inventories US shrink": http://www.miamiherald.com/news/top-AP-stories/story/679959.htmlOTRAS NOTICIAS "CNN" publica: "U.S. cancels nuclear deal with Russia": http://edition.cnn.com/2008/WORLD/europe/09/08/us.russia.ap/index.html?iref=topnews"La Nación" informa sobre reunión de la OPEP en Viena: "En vísperas de la reunión en Viena: Busca la OPEP estabilizar el precio del crudo: Mañana se reúnen los representantes de la Organización de Países Exportadores de Petróleo en la capital austríaca; podrían recortar la producción para modificar los valores":http://www.lanacion.com.ar/nota.asp?nota_id=1047745 "El Tiempo" de Colombia anuncia: "Tribunal exime a Holanda de responsabilidad en el genocidio de Srebrenica": http://www.eltiempo.com/mundo/europa/home/tribunal-exime-a-holanda-de-responsabilidad-en-el-genocidio-de-srebrenica_4521629-1

The authors have read the journal's policy and the authors of this manuscript have the following competing interests: Bruce M. Psaty (BMP) serves on the DSMB of a clinical trial funded by Zoll Lifecor and on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. Barbara V. Howard (BVH) has a contract from National Heart, Lung, and Blood Institute (NHLBI). Brenda W.J.H. Penninx (BWJHP) has received research funding (non-related to the work reported here) from Jansen Research and Boehringer Ingelheim. Mike A. Nalls (MAN) is supported by a consulting contract between Data Tecnica International LLC and the National Institute on Aging (NIA), National Institutes of Health (NIH), Bethesda, MD, USA. MAN also consults for Illumina Inc., the Michael J. Fox Foundation, and the University of California Healthcare. MAN also has commercial affiliation with Data Tecnica International, Glen Echo, MD, USA. Mark J. Caulfield (MJC) has commercial affiliation and is Chief Scientist for Genomics England, a UK government company. OHF is supported by grants from Metagenics (on women's health and epigenetics) and from Nestlé (on child health). Peter S. Sever (PSS) is financial supported from several pharmaceutical companies which manufacture either blood pressure lowering or lipid lowering agents, or both, and consultancy fees. Paul W. Franks (PWF) has been a paid consultant in the design of a personalized nutrition trial (PREDICT) as part of a private-public partnership at Kings College London, UK, and has received research support from several pharmaceutical companies as part of European Union Innovative Medicines Initiative (IMI) projects. Terho Lehtimäki (TL) is employed by Fimlab Ltd. Ozren Polašek (OP) is employed by Gen‐info Ltd. There are no patents, products in development, or marked products to declare. All the other authors have declared no competing interests exist. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. ; International audience ; Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcohol consumption interaction for BP might identify additional BP loci and contribute to the understanding of alcohol-related BP regulation. We conducted a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions. In Stage 1, genome-wide discovery meta-analyses in ≈131K individuals across several ancestry groups yielded 3,514 SNVs (245 loci) with suggestive evidence of association (P < 1.0 x 10-5). In Stage 2, these SNVs were tested for independent external replication in ≈440K individuals across multiple ancestries. We identified and replicated (at Bonferroni correction threshold) five novel BP loci (380 SNVs in 21 genes) and 49 previously reported BP loci (2,159 SNVs in 109 genes) in European ancestry, and in multi-ancestry meta-analyses (P < 5.0 x 10-8). For African ancestry samples, we detected 18 potentially novel BP loci (P < 5.0 x 10-8) in Stage 1 that warrant further replication. Additionally, correlated meta-analysis identified eight novel BP loci (11 genes). Several genes in these loci (e.g., PINX1, GATA4, BLK, FTO and GABBR2) have been previously reported to be associated with alcohol consumption. These findings provide insights into the role of alcohol consumption in the genetic architecture of hypertension.

The authors have read the journal's policy and the authors of this manuscript have the following competing interests: Bruce M. Psaty (BMP) serves on the DSMB of a clinical trial funded by Zoll Lifecor and on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. Barbara V. Howard (BVH) has a contract from National Heart, Lung, and Blood Institute (NHLBI). Brenda W.J.H. Penninx (BWJHP) has received research funding (non-related to the work reported here) from Jansen Research and Boehringer Ingelheim. Mike A. Nalls (MAN) is supported by a consulting contract between Data Tecnica International LLC and the National Institute on Aging (NIA), National Institutes of Health (NIH), Bethesda, MD, USA. MAN also consults for Illumina Inc., the Michael J. Fox Foundation, and the University of California Healthcare. MAN also has commercial affiliation with Data Tecnica International, Glen Echo, MD, USA. Mark J. Caulfield (MJC) has commercial affiliation and is Chief Scientist for Genomics England, a UK government company. OHF is supported by grants from Metagenics (on women's health and epigenetics) and from Nestlé (on child health). Peter S. Sever (PSS) is financial supported from several pharmaceutical companies which manufacture either blood pressure lowering or lipid lowering agents, or both, and consultancy fees. Paul W. Franks (PWF) has been a paid consultant in the design of a personalized nutrition trial (PREDICT) as part of a private-public partnership at Kings College London, UK, and has received research support from several pharmaceutical companies as part of European Union Innovative Medicines Initiative (IMI) projects. Terho Lehtimäki (TL) is employed by Fimlab Ltd. Ozren Polašek (OP) is employed by Gen‐info Ltd. There are no patents, products in development, or marked products to declare. All the other authors have declared no competing interests exist. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. ; International audience ; Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcohol consumption interaction for BP might identify additional BP loci and contribute to the understanding of alcohol-related BP regulation. We conducted a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions. In Stage 1, genome-wide discovery meta-analyses in ≈131K individuals across several ancestry groups yielded 3,514 SNVs (245 loci) with suggestive evidence of association (P < 1.0 x 10-5). In Stage 2, these SNVs were tested for independent external replication in ≈440K individuals across multiple ancestries. We identified and replicated (at Bonferroni correction threshold) five novel BP loci (380 SNVs in 21 genes) and 49 previously reported BP loci (2,159 SNVs in 109 genes) in European ancestry, and in multi-ancestry meta-analyses (P < 5.0 x 10-8). For African ancestry samples, we detected 18 potentially novel BP loci (P < 5.0 x 10-8) in Stage 1 that warrant further replication. Additionally, correlated meta-analysis identified eight novel BP loci (11 genes). Several genes in these loci (e.g., PINX1, GATA4, BLK, FTO and GABBR2) have been previously reported to be associated with alcohol consumption. These findings provide insights into the role of alcohol consumption in the genetic architecture of hypertension.

The authors have read the journal's policy and the authors of this manuscript have the following competing interests: Bruce M. Psaty (BMP) serves on the DSMB of a clinical trial funded by Zoll Lifecor and on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. Barbara V. Howard (BVH) has a contract from National Heart, Lung, and Blood Institute (NHLBI). Brenda W.J.H. Penninx (BWJHP) has received research funding (non-related to the work reported here) from Jansen Research and Boehringer Ingelheim. Mike A. Nalls (MAN) is supported by a consulting contract between Data Tecnica International LLC and the National Institute on Aging (NIA), National Institutes of Health (NIH), Bethesda, MD, USA. MAN also consults for Illumina Inc., the Michael J. Fox Foundation, and the University of California Healthcare. MAN also has commercial affiliation with Data Tecnica International, Glen Echo, MD, USA. Mark J. Caulfield (MJC) has commercial affiliation and is Chief Scientist for Genomics England, a UK government company. OHF is supported by grants from Metagenics (on women's health and epigenetics) and from Nestlé (on child health). Peter S. Sever (PSS) is financial supported from several pharmaceutical companies which manufacture either blood pressure lowering or lipid lowering agents, or both, and consultancy fees. Paul W. Franks (PWF) has been a paid consultant in the design of a personalized nutrition trial (PREDICT) as part of a private-public partnership at Kings College London, UK, and has received research support from several pharmaceutical companies as part of European Union Innovative Medicines Initiative (IMI) projects. Terho Lehtimäki (TL) is employed by Fimlab Ltd. Ozren Polašek (OP) is employed by Gen‐info Ltd. There are no patents, products in development, or marked products to declare. All the other authors have declared no competing interests exist. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. ; International audience ; Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcohol consumption interaction for BP might identify additional BP loci and contribute to the understanding of alcohol-related BP regulation. We conducted a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions. In Stage 1, genome-wide discovery meta-analyses in ≈131K individuals across several ancestry groups yielded 3,514 SNVs (245 loci) with suggestive evidence of association (P < 1.0 x 10-5). In Stage 2, these SNVs were tested for independent external replication in ≈440K individuals across multiple ancestries. We identified and replicated (at Bonferroni correction threshold) five novel BP loci (380 SNVs in 21 genes) and 49 previously reported BP loci (2,159 SNVs in 109 genes) in European ancestry, and in multi-ancestry meta-analyses (P < 5.0 x 10-8). For African ancestry samples, we detected 18 potentially novel BP loci (P < 5.0 x 10-8) in Stage 1 that warrant further replication. Additionally, correlated meta-analysis identified eight novel BP loci (11 genes). Several genes in these loci (e.g., PINX1, GATA4, BLK, FTO and GABBR2) have been previously reported to be associated with alcohol consumption. These findings provide insights into the role of alcohol consumption in the genetic architecture of hypertension.