Suchergebnisse

1 Alcohol Use and Abuse: Historical Perspective and Present Trends -- 1. Alcohol Use in Historical Perspective -- 2. Alcohol Consumption and Alcohol Problems -- 3. Development of the Concept(s) of Alcoholism -- 4. References -- 2 The Genetics of Alcoholism -- 1. Types of Studies Supporting a Genetic Influence in Alcoholism -- 2. Possible Biological Mechanisms for a Genetic Influence in Alcoholism -- 3. A Prospective Search for the Biological Determinants of Alcoholism -- 4. Summary -- 5. References -- 3 The Absorption, Distribution, and Metabolism of Ethanol and Its Effects on Nutrition and Hepatic Function -- 1. Introduction -- 2. Absorption and Distribution -- 3. Pharmacokinetics and Alcohol Elimination Rates -- 4. Processes and Organs Responsible for Ethanol Elimination -- 5. Significant Pathways of Ethanol Metabolism -- 6. Enzymes That Oxidize Ethanol to Acetaldehyde -- 7. Enzymes That Oxidize Acetaldehyde to Acetate -- 8. Control of Ethanol and Acetaldehyde Metabolism in Liver -- 9. Effect of Chronic Ethanol Ingestion on Alcohol Elimination Rate -- 10. Chronic Ethanol Ingestion and Nutrition -- 11. Ethanol Oxidation and Hepatic Metabolism -- 12. References -- 4 Effects of Ethanol upon Organ Systems Other than the Central Nervous System -- 1. Introduction -- 2. Ethanol and the Gastrointestinal Tract -- 3. Muscle Systems -- 4. The Hematologic System -- 5. Kidney Disease and Alcoholism -- 6. Pulmonary Disease and Alcoholism -- 7. The Endocrine System and Alcoholism -- 8. Effects of Ethanol on the Hypothalamic-Pituitary-Adrenal Axis -- 9. Effects of Alcohol on the Hypothalamic-Pituitary-Thyroidal Axis -- 10. The Effects of Alcohol on Growth Hormone and Prolactin -- 11. Effects of Alcohol on Vasopressin and Oxytocin -- 12. Biological Markers of Alcoholism -- 13. References -- 5 Ethanol and the Central Nervous System -- 1. Ethanol and Behavior -- 2. Ethanol and Membrane Structure and Function -- 3. Ethanol and Electrical Cellular Activity -- 4. Ethanol and Synaptic Transmission -- 5. Ethanol and Metabolism -- 6. Consequences of Long-term Ethanol Consumption -- 7. Summary -- 8. References -- 6 Neurologic Diseases Associated with Chronic Alcohol Abuse -- 1. Introduction -- 2. Physical Dependence -- 3. Chronic Diseases of the Central Nervous System -- 4. Peripheral Polyneuropathy -- 5. Nutritional Deficiencies -- 6. Conclusions -- 7. References -- 7 Biology of Tolerance and Dependence -- 1. Introduction to Tolerance and Dependence -- 2. Factors Contributing to Tolerance and Dependence -- 3. Classifications and Definitions of Tolerance -- 4. Biochemical Determinants of Ethanol Tolerance -- 5. Characteristics of Physical Dependence on Ethanol -- 6. Etiological Factors Contributing to the Development of Physical Dependence -- 7. Neurochemical Systems Determining Physical Dependence -- 8. Pharmacologic Management of the Acute Alcohol Withdrawal Syndrome -- 9. References -- 8 Alcohol Consumption and Prenatal Development -- 1. Fetal Alcohol Syndrome/Fetal Alcohol Effects -- 2. Alcohol as a Teratogen in Animals, 1973–1979 -- 3. Critical Discussion and General Conclusions -- 4. References -- 9 Interaction of Ethanol with Other Drugs -- 1. Introduction -- 2. Centrally Acting Compounds -- 3. References -- 10 Psychological Correlates and Explantions of Alcohol Use and Abuse -- 1. Psychodynamic Models -- 2. The Disease Model -- 3. Behavioral and Social-Learning Approach -- 4. Future Directions -- 5. References -- 11 Alcoholism Treatment Approaches: Patient Variables, Treatment Variables -- 1. Critical View of Treatment Outcome Evaluation -- 2. Treatment Variables -- 3. Patient Variables -- 4. Implications -- 5. References -- 12 Prevention of Alcohol Abuse -- 1. Approaches to Prevention -- 2. Alcohol Education -- 3. Mass Media -- 4. Alcohol Control Legislation -- 5. Conclusions -- 6. References.

BACKGROUND/AIMS—Landmines have long been used in conventional warfare. These are antipersonnel mines which continue to injure people long after a ceasefire without differentiating between friend or foe, soldier or civilian, women or children. This study focuses on Afghan non-combatants engaged in mine clearing operations in Afghanistan in the aftermath of the Russo-Afghan war. The patterns and types of injuries seen are described and experiences in their management, ways, and means to prevent them, and recommendations for the rehabilitation of the affected individuals are given. METHODS—It is a retrospective and analytical study of 84 patients aged 19-56 years who sustained mine blast injuries during mine clearing operations in Afghanistan from November 1992 to January 1996. The study was carried out at a military hospital with tertiary care facilities. The patients were divided into three groups on the basis of their injuries. Group 1 required only general surgical attention, group 2 sustained only ocular injuries, while group 3 had combined ocular and general injuries. Patients in groups 2 and 3 were treated in two phases. The first phase aimed at immediate restoration of the anatomy, while restoration of function wherever possible was done in subsequent surgical procedures in the second phase. RESULTS—It was observed that 51 out of 84 patients (60.7%) had sustained ocular trauma of a variable degree as a result of the blasts. The mean age of the victims was 29 years and they were all male. A total of 91 eyes of 51 patients (89.2%) had been damaged. Bilaterality of damage was seen in 40 (78.4%) patients. Most, 34 (37.3%), eyes became totally blind (NPL). Only a few escaped with injury mild enough not to impair vision. Foreign bodies, small and multiple, were found in the majority of eyes; most, however, were found in the anterior segment, and posterior segment injuries were proportionally less. CONCLUSIONS—The prevalence of blindness caused by mine blast injuries is quite high. The resulting psychosocial ...

Human service professionals may experience conflict about using their authority and the power that accompanies it when they must reconcile their humanitarian values about practice with requirements and expectations of the environmental context in which they operate. The author suggests that the political and economic environment, gender issues, and the impact of these on the exchange between client and worker are factors that cause uneasiness for practitioners in exercising authority.

Bibliography: pages 201-214. ; Environmental degradation is widely regarded as an integral part of South Africa's homeland areas. Conventional thinking often blames so-called traditional farming practices, attitudes and values for this situation. In other words, the blame is placed with the residents of the areas and environmental degradation is explained away as the result of a particular cultural make-up. Following this line of thought, education via agricultural extension is mooted as the primary solution to what is regarded as an inherent problem. The central concern of this dissertation is to examine the dynamics of natural resource management by residents of a rural area in KwaZulu known as oBivane. The thesis shows that the conditions leading to environmental degradation are best seen as the result of particular historical and political processes and not simply as the results of particular patterns of behaviour that are culturally driven. These processes, given primary impetus by massive population influx onto a restricted land base and combined with the peculiarities of differential access to resources and the need to preserve the interests of elite groups, have forced sectors of the South African population into situations where physical survival has necessarily had grave environmental cost. One of the consequences of apartheid policies has been to institutionalise environmental degradation in particular areas of the country.