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Cover -- Half Title Page -- Title Page -- Copyright Page -- Declaration -- About the Editor -- Table of Contents -- List of Contributors -- List of Abbreviations -- Preface -- Chapter 1 Antimicrobial Resistance: A Priority for Global Health Action -- References -- Chapter 2 Antimicrobial Resistance Among Migrants in Europe: A Systematic Review and Meta-Analysis -- Summary -- Introduction -- Methods -- Results -- Discussion -- Contributors -- Acknowledgments -- References -- Chapter 3 Neisseria Gonorrhoeae Molecular Typing For Understanding Sexual Networks And Antimicrobial Resistance Transmission: A Systematic Review -- Summary -- Introduction -- Methods -- Results -- Discussion -- Author Contribution -- Acknowledgements -- References -- Chapter 4 Enhancing Pharmacists' Role In Developing Countries To Overcome The Challenge Of Antimicrobial Resistance: A Narrative Review -- Abstract -- Background -- Method -- Results -- Discussion -- Conclusion -- Acknowledgements -- Authors' Contributions -- References -- Chapter 5 Antimicrobial Resistance Mechanisms and Potential Synthetic Treatments -- Abstract -- Antimicrobial Resistance Mechanisms -- Molecular Applications Against AMR Bacteria -- Conclusion -- Authors' Contributions -- References -- Chapter 6 Antimicrobial Activity of Cerium Oxide Nanoparticles on Opportunistic Microorganisms: A Systematic Review -- Abstract -- Introduction -- Material and Methods -- Results and Discussion -- Conclusions -- References -- Chapter 7 Antimicrobial Resistance Mechanisms among Campylobacter -- Abstract -- Introduction -- Antimicrobial Resistance Mechanisms in Campylobacter -- Factors Influencing Antimicrobial Resistance of Campylobacter -- Epidemiology of Fluoroquinolone And Macrolide Resistance in Campylobacter -- Development And Transmission Of Antibiotic Resistance in Campylobacter.
The position paper of the European Association of Hospital Pharmacists (EAHP) highlights the importance of the prudent use of antimicrobial drugs through antibiotic stewardship to ensure efficient therapy for patients with life-threatening infections. EAHP calls on national governments and health system managers to utilise the specialised background and knowledge of the hospital pharmacist in multi-professional antibiotic stewardship teams. In addition, the paper recommends the universal application of infection prevention and control measures among healthcare professionals. Due to the lack of funding, EAHP urges increased investment to support the development of innovative proposals and the encouragement of practice-based research projects to investigate new fields of infectious disease control such as immunotherapy and to optimise the cost-effectiveness of systems for surveillance on antibiotic use and resistance. In relation to the 'One Health approach' of the European Commission, EAHP strongly supports regulatory oversight and proper implementation of measures in the veterinary and agriculture sectors at European, national and local level.
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In: Lo , C & Thomas , N 2020 , ' The Macrosecuritization of Antimicrobial Resistance in China ' , Journal of Global Security Studies , vol. 5 , no. 2 , pp. 361-378 . https://doi.org/10.1093/jogss/ogz038
The global spread of antimicrobial resistance (AMR) is an existential threat to humanity, one that has generated a macrosecuritizing response by states and international organizations. Since the turn of the century, China has been a source of numerous infectious disease outbreaks. It is also the origin of the MCR-1 gene that confers resistance to colistin, a 'last line' antibiotic deployed against multidrug resistant infections. With the largest population and its status as a major supplier of produce, evaluating Chinese responses to AMR is critical to understanding the efficacy of the global response. Combining both knowledge of Chinese politics and health security, this paper analyses how Chinese actors have responded to the threat in the public and animal health sectors as well as the domestic and international implications of these responses. Based on interviews with key Chinese and international officials, scientists, and public health specialists as well as farmers and consumers, we argue that the securitization of AMR in China is currently more concerned with domestic policy and resource competition than with addressing the existential health threat. Without a greater alignment of AMR strategies within China, macrosecuritizing efforts to address the threat globally cannot succeed.
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In: Lo , C & Thomas , N 2018 , ' The Macrosecuritization of Antimicrobial Resistance in Asia ' , Australian Journal of International Affairs , vol. 72 , no. 6 , pp. 567-583 . https://doi.org/10.1080/10357718.2018.1534939
This article has two objectives. Drawing on the framework provided by macrosecuritization, this article first explores global responses to AMR. Secondly, in shifting the analytical lens to Asia, the article then evaluates how successful this process has been in a regional context. Considering the two objectives, two inter-related arguments are proposed. First, even though AMR can be considered a quintessential and successful macrosecuritization case at the global level, within Asia the operationalisation of AMR strategies is limited by power and resource politics within the states. Second, the anthropocentric nature of health security is limited when it comes to address the threat posed by AMR. Overcoming this limitation requires a One Health approach. However, the successful articulation of this approach has proven challenging in Asia where middle-level actors pull away from the process in pursuit of other agendas. As a result, while macrosecuritization provides a useful tool for understanding how AMR and similar health threats are addressed, it is necessary to understand the local realities within which the process is embedded.
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National institutions/organisations participating in EARS-Net - Portugal: National Institute of Health Doutor Ricardo Jorge (Caniça, M., Fernandes, P.A., Manageiro, V.) ; The results presented in this report are based on antimicrobial resistance data from invasive isolates reported to EARS-Net by 30 European Union (EU) and European Economic Area (EEA) countries in 2017 (data referring to 2016), and on trend analyses of data reported by the participating countries for the period 2013 to 2016. As in previous years, the antimicrobial resistance situation in Europe displays wide variations depending on the bacterial species, antimicrobial group and geographical region. For several bacterial species–antimicrobial group combinations, a north-to-south and a west-to-east gradient is evident in Europe. In general, lower resistance percentages were reported by countries in the north while higher percentages were reported in the south and east of Europe. These differences are most likely related to variations in antimicrobial use, infection prevention and control practices, and dissimilarities in diagnostic and healthcare utilisation patterns in the countries. ; info:eu-repo/semantics/publishedVersion
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In: Environmental science and pollution research: ESPR, Band 25, Heft 19, S. 18377-18384
ISSN: 1614-7499
In: Oxford Research Encyclopedia of Politics
"Antimicrobial Resistance as a Global Health Crisis" published on by Oxford University Press.
In animal husbandry, antimicrobial agents have been administered as supplements to increase production over the last 60 years. Large-scale animal production has increased the importance of antibiotic management because it may favor the evolution of antimicrobial resistance and select resistant strains. Brazil is a significant producer and exporter of animal-derived food. Although Brazil is still preparing a national surveillance plan, several changes in legislation and timely programs have been implemented. Thus, Brazilian data on antimicrobial resistance in bacteria associated with animals come from official programs and the scientific community. This review aims to update and discuss the available Brazilian data on this topic, emphasizing legal aspects, incidence, and genetics of the resistance reported by studies published since 2009, focusing on farm animals and derived foods with the most global public health impact. Studies are related to poultry, cattle, and pigs, and mainly concentrate on non-typhoid Salmonella, Escherichia coli, and Staphylococcus aureus. We also describe legal aspects of antimicrobial use in this context ; and the current occurrence of genetic elements associated with resistance to beta-lactams, colistin, and fluoroquinolones, among other antimicrobial agents. Data here presented may be useful to provide a better understanding of the Brazilian status on antimicrobial resistance related to farm animals and animal-derived food products.
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In: Journal of global security studies
ISSN: 2057-3189
Abstract
The global spread of antimicrobial resistance (AMR) is an existential threat to humanity, one that has generated a macrosecuritizing response by states and international organizations. Since the turn of the century, China has been a source of numerous infectious disease outbreaks. It is also the origin of the MCR-1 gene, which confers resistance to colistin, a "last-line" antibiotic deployed against multidrug-resistant infections. With the largest population in the world, coupled with its status as a major supplier of agricultural produce, evaluating Chinese responses to AMR is critical to understanding the efficacy of the global response. Drawing on knowledge of both Chinese politics and health security, this article analyzes how Chinese actors have responded to the threat in the public and animal health sectors as well as the domestic and international implications of these responses. Based on interviews with key Chinese and international officials, scientists, and public health specialists, as well as farmers and consumers, we argue that the securitization of AMR in China is currently more concerned with domestic policy and resource competition than with addressing the existential health threat. Without a greater alignment of AMR strategies within China, macrosecuritizing efforts to address the threat globally cannot succeed.
Antimicrobial resistance poses a growing threat to public health and the provision of health care. Its surveillance should provide up-to-date and relevant information to monitor the appropriateness of therapy guidelines, antibiotic formulary, antibiotic stewardship programmes, public health interventions, infection control policies, and antimicrobial development. In Europe, although the European Antimicrobial Resistance Surveillance Network provides annual reports on monitored resistant bacteria, national surveillance efforts are still fragmented and heterogeneous, and have substantial structural problems and issues with laboratory data. Most incidence and prevalence data cannot be linked with relevant epidemiological, clinical, or outcome data. Genetic typing, to establish whether trends of antimicrobial resistance are caused by spread of resistant strains or by transfer of resistance determinants among different strains and species, is not routinely done. Furthermore, laboratory-based surveillance using only clinical samples is not likely to be useful as an early warning system for emerging pathogens and resistance mechanisms. Insufficient coordination of surveillance systems of human antimicrobial resistance with animal surveillance systems is even more concerning. Because results from food surveillance are considered commercially sensitive, they are rarely released publicly by regulators. Inaccurate or incomplete surveillance data delay a translational approach to the threat of antimicrobial resistance and inhibit the identification of relevant target microorganisms and populations for research and the revitalisation of dormant drug-discovery programmes. High-quality, comprehensive, and real-time surveillance data are essential to reduce the burden of antimicrobial resistance. Improvement of national antimicrobial resistance surveillance systems and better alignment between human and veterinary surveillance systems in Europe must become a scientific and political priority, coordinated with international ...
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In: Bulletin of the World Health Organization: the international journal of public health = Bulletin de l'Organisation Mondiale de la Santé, Band 97, Heft 6, S. 384-385
ISSN: 1564-0604
In: Bulletin of the World Health Organization: the international journal of public health = Bulletin de l'Organisation Mondiale de la Santé, Band 94, Heft 9, S. 638-639
ISSN: 1564-0604
In: Journal of intercultural management and ethics: JIME, Band 3, Heft 1, S. 39-43
ISSN: 2601-5749
In: Bulletin of the atomic scientists, Band 75, Heft 6, S. 286-289
ISSN: 1938-3282