Suchergebnisse

Cover -- Half Title Page -- Title Page -- Copyright Page -- Declaration -- About the Editor -- Table of Contents -- List of Contributors -- List of Abbreviations -- Preface -- Chapter 1 Antimicrobial Resistance: A Priority for Global Health Action -- References -- Chapter 2 Antimicrobial Resistance Among Migrants in Europe: A Systematic Review and Meta-Analysis -- Summary -- Introduction -- Methods -- Results -- Discussion -- Contributors -- Acknowledgments -- References -- Chapter 3 Neisseria Gonorrhoeae Molecular Typing For Understanding Sexual Networks And Antimicrobial Resistance Transmission: A Systematic Review -- Summary -- Introduction -- Methods -- Results -- Discussion -- Author Contribution -- Acknowledgements -- References -- Chapter 4 Enhancing Pharmacists' Role In Developing Countries To Overcome The Challenge Of Antimicrobial Resistance: A Narrative Review -- Abstract -- Background -- Method -- Results -- Discussion -- Conclusion -- Acknowledgements -- Authors' Contributions -- References -- Chapter 5 Antimicrobial Resistance Mechanisms and Potential Synthetic Treatments -- Abstract -- Antimicrobial Resistance Mechanisms -- Molecular Applications Against AMR Bacteria -- Conclusion -- Authors' Contributions -- References -- Chapter 6 Antimicrobial Activity of Cerium Oxide Nanoparticles on Opportunistic Microorganisms: A Systematic Review -- Abstract -- Introduction -- Material and Methods -- Results and Discussion -- Conclusions -- References -- Chapter 7 Antimicrobial Resistance Mechanisms among Campylobacter -- Abstract -- Introduction -- Antimicrobial Resistance Mechanisms in Campylobacter -- Factors Influencing Antimicrobial Resistance of Campylobacter -- Epidemiology of Fluoroquinolone And Macrolide Resistance in Campylobacter -- Development And Transmission Of Antibiotic Resistance in Campylobacter.

1 The Development of Antimicrobial Agents, Past, Present and Future -- The social and economic importance of antimicrobial agents -- An outline of the historical development of antimicrobial agents and of chemotherapeutic theories -- Reasons for studying the biochemistry of antimicrobial compounds -- Development of biochemical knowledge of antimicrobial action -- Scope and layout of the present book -- 2 The Bacterial Cell Wall — A Vulnerable Shield -- Functions of the wall -- Wall structure -- Structure and biosynthesis of peptidoglycan -- Antibiotics that inhibit peptidoglycan biosynthesis -- 3 Antiseptics, Antibiotics and the Cell Membrane -- Microbe killers: antiseptics and disinfectants -- Polypeptide antibiotics -- Ionophoric antibiotics -- Polyene antibiotics -- An inhibitor of membrane phospholipid biosynthesis -- 4 Inhibitors of Nucleic Acid Synthesis -- Compounds affecting the biosynthesis of nucleotide precursors -- Inhibitors of nucleic acid synthesis at the polymerization level -- 5 Inhibitors of Protein Synthesis -- Ribosomes -- Stages in protein biosynthesis -- Puromycin -- Inhibitors of aminoacyl-tRNA formation -- Inhibitors of initiation-complex formation and tRNA—ribosome interaction -- Inhibitors of peptide bond formation and translocation -- Nucleic acid synthesis during inhibition of protein synthesis -- Effects of inhibitors of 70S ribosomes on eukaryotic cells -- 6 Antifungal, Antiprotozoal and Antiviral Agents -- Compounds used to treat protozoal diseases -- Compounds used to treat fungal diseases -- Compounds used to treat virus diseases -- 7 Penetrating the Defences: How Antimicrobial Agents Reach Their Targets -- Cellular permeability barriers to drug penetration -- Some examples of modes of penetration of antimicrobial agents -- The exploitation of transport systems in the design of new antimicrobial agents -- 8 Resistance to Antimicrobial Drugs -- The genetics of drug resistance -- Spread of drug resistance by gene transfer -- Biochemical mechanisms of drug resistance -- Bacterial tolerance -- Practical approaches to the control of drug resistance.

"This book explores the role that environmental distribution of antimicrobial resistance genes and antibiotics plays in ecosystem and human health. The text features a multi-disciplinary framework that connects microbiology, environmental toxicology, and chemistry to assess human and ecological risk associated with exposure to antibiotics or antibiotic resistance genes as environmental contaminants. It also considers alternate uses and functions for antimicrobial compounds other than those intended for medicinal purposes in humans, animals, and fish. Recognizing the connectivity between overlapping complex systems, the book discusses the subject from the perspective of an ecosystem approach"--

Natural additives are increasingly favoured over synthetic ones as methods of ensuring food safety and long shelf-life. The antimicrobial properties of both plant-based antimicrobials such as essential oils and proteins such as bacteriocins are used in, for example, edible preservative films, in food packaging and in combination with synthetic preservatives for maximum efficacy. New developments in delivery technology such as nanoencapsulation also increase the potential of natural antimicrobials for widespread use in industry. Part one introduces the different types of natural antimicrobials for food applications. Part two covers methods of application, and part three looks at determining the effectiveness of natural antimicrobials in food. Part four focuses on enhancing quality and safety, and includes chapters on specific food products. Reviews different types of antimicrobials used in food safety and qualityCovers how antimicrobials are created to be used in different foodsExamines how the antimicrobials are used in foods to enhance the safety and quality

This volume summarizes and updates information about antibiotics and antimicrobial resistance (AMR)/antibiotic resistant genes (ARG) production, including their entry routes in soil, air, water and sediment, their use in hospital and associated waste, global and temporal trends in use and spread of antibiotics, AMR and ARG. Antimicrobial/antibiotic resistance genes due to manure and agricultural waste applications, bioavailability, biomonitoring, and their Epidemiological, ecological and public health effects. The book addresses the antibiotic and AMR/ARG risk assessment and treatment technologies, for managing antibiotics and AMR/ARG impacted environments The book's expert contributions span 26 chapters, and offer a comprehensive framework for better understanding and analyzing the environmental and social impacts of antibiotics and AMR/ARGs. Readers will have access to recent and updated models regarding the interpretation of antibiotics and AMR/ARGs in environment and biomonitoring studies, and will learn about the management options require to appropriately mitigate environmental contaminants and pollution. The book will be of interest to students, teachers, researchers, policy makers and environmental organizations.

Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy offers an up-to-date perspective on recent research findings regarding the application and use of these materials for disease treatment and prevention. Various types of currently investigated bioactive materials, including therapeutic nanostructures and antimicrobial hydrogels are discussed, as are their properties, impact and future role in therapeutic applications. The book will be extremely useful for new researchers who want to explore more information on the use of bioactive materials or for more experienced researchers who are interested in new trends and specific applications