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This book constitutes the proceedings of the 16th International Conference on Social, Cultural, and Behavioral Modeling, SBP-BRiMS 2023, which was held in Pittsburgh, PA, USA in September 2023. The 31 full papers presented in this volume were carefully reviewed and selected from 73 submissions. The papers were organized in topical sections as follows: Detecting malign influence; human behavior modeling; and social-cyber behavior modeling

The Initial Impact of Technology Enabled Relationship Creation in Rural Lebanon -- Meaning of fun in hotel gamified applications -- Riding against the algorithm: Algorithmic management in on-demand food delivery -- "Domestic or International?" The Impact of Cognitive Absorption of Short-Form Videos on Tourists' Post-COVID Travel Intention: An exploratory study on Douyin -- A Re-rank Algorithm for Online Hotel Search -- Exploring Customer Experience with Service Robots in Hospitality and Tourism: Activity Theory Perspective -- How do affect the infusion of smart technology and mindfulness of tourism SMEs on competitiveness -- User Experience and Spatial Presence in a Walk-in Augmented Reality 3D Model for Tourists.

Computer Science and Information Technology -- Zero Configuration Comfort and Accessibility in Smart Environments -- The impact of the evolution of Operating Systems on older Web Applications -- Method for Evaluating the Performance of Web-Based APIs -- Application of Traditional and Deep Learning Algorithms for Sentiment Analysis of Global Warming Tweets -- 3D Simulation and Comparative Analysis of Immune System Cell Micro-Level Responses in Virtual Reality and Mixed Reality Environments -- Developing a 3D Laparoscopy Training Application to Assess the Efficacy in Virtual Reality Environments -- Collaborating with Agents in Architectural Design and Decision-Making Process: Top-down and Bottom-up Case Studies Using Reinforcement Learning -- Health Technology and Medicine -- 5G and IoT for Intelligent Healthcare: AI and Machine Learning Approaches— A review -- Experience of Visually-Impaired Children in the Enjoyment of Cartoons -- A review of wearable sensor patches for patient monitoring -- Enhancing Student Well-being: the Impact of a Mindful-ness-Based Program (Mind7+) on Stress, Anxiety, Sleep Quality, and Social Interactions in a sample of Portuguese University Students -- Algorithm for Diagnosis of Metabolic Syndrome and Heart Failure using CPET Biosignals via SVM and Wavelet Transforms -- Meal Suggestions for Caregivers and Indecisive Individuals Without a Set Food Plan.