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The article concludes that the factor of globalization has an important meaning in the disclosure of causes and models of reginalization. It shows that the trend of globalization intensifies the transfer to the acknowledgment of the principle of people sovereignity and security of nation and a citizen. States are trying to compensate negative consequences of national economics openness and forming internal regional education. In western countries the search of combined solution of problems and formation of institutes that are adequate to the tendencies of globalization and regionalization is carried out. Regionalism becomes a motive force in power institute reformation and the basic factor of federalization. For Russia where real federalism has not been formed yet, it is very important not to allow the transfer of regionalization into regionalism that causes the phenomenon of separatism. The role of local government should be increased and equal social guarantees for people should be created. ; The article concludes that the factor of globalization has an important meaning in the disclosure of causes and models of reginalization. It shows that the trend of globalization intensifies the transfer to the acknowledgment of the principle of people sovereignity and security of nation and a citizen. States are trying to compensate negative consequences of national economics openness and forming internal regional education. In western countries the search of combined solution of problems and formation of institutes that are adequate to the tendencies of globalization and regionalization is carried out. Regionalism becomes a motive force in power institute reformation and the basic factor of federalization. For Russia where real federalism has not been formed yet, it is very important not to allow the transfer of regionalization into regionalism that causes the phenomenon of separatism. The role of local government should be increased and equal social guarantees for people should be created.