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Bioaccumulation and toxicity of mineral oil hydrocarbons in rats ‐ specificity of different subclasses of a broad mixture relevant for human dietary exposures
In: EFSA supporting publications, Band 14, Heft 2
ISSN: 2397-8325
Risk assessment of contaminants in food and feed
In: EFSA journal, Band 10, Heft 10
ISSN: 1831-4732
Presence of microplastics and nanoplastics in food, with particular focus on seafood
In: EFSA CONTAM Panel & Rose , M 2016 , ' Presence of microplastics and nanoplastics in food, with particular focus on seafood ' EFSA Journal . DOI:10.2903/j.efsa.2016.4501
Following a request from the German Federal Institute for Risk Assessment (BfR), the EFSA Panel for Contaminants in the Food Chain was asked to deliver a statement on the presence of microplastics and nanoplastics in food, with particular focus on seafood. Primary microplastics are plastics originally manufactured to be that size, while secondary microplastics originate from fragmentation. Nanoplastics can originate from engineered material or can be produced during fragmentation of microplastic debris. Microplastics range from 0.1 to 5,000 μm and nanoplastics from approximately 1 to 100 nm (0.001–0.1 μm). There is no legislation for microplastics and nanoplastics as contaminants in food. Methods are available for identification and quantification of microplastics in food, including seafood. Occurrence data are limited. In contrast to microplastics no methods or occurrence data in food are available for nanoplastics. Microplastics can contain on average 4% of additives and the plastics can adsorb contaminants. Both additives and contaminants can be of organic as well of inorganic nature. Based on a conservative estimate the presence of microplastics in seafood would have a small effect on the overall exposure to additives or contaminants. Toxicity and toxicokinetic data are lacking for both microplastics and nanoplastics for a human risk assessment. It is recommended that analytical methods should be further developed for microplastics and developed for nanoplastics and standardised, in order to assess their presence, identity and to quantify their amount in food. Furthermore, quality assurance should be in place and demonstrated. For microplastics and nanoplastics, occurrence data in food, including effects of food processing, in particular, for the smaller sized particles (< 150 μm) should be generated. Research on the toxicokinetics and toxicity, including studies on local effects in the gastrointestinal (GI) tract, are needed as is research on the degradation of microplastics and potential formation of nanoplastics in the human GI tract.
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Risk assessment of grilled and barbecued food
In: Food risk assess Europe, Band 2, Heft 2
ISSN: 2940-1399
Why Travel?: Understanding our Need to Move and How it Shapes our Lives
Supported by the Independent Transport Commission (ITC): a registered charity Why travel? What motivations underpin the journeys we make? And how can we make decisions that improve our travel experiences? Arguing that the desire to move is a purpose in itself, this book brings together leading experts to provide insights from multiple viewpoints across the sciences, arts and humanities. Together, they examine key travel motivations, including the importance of travel for human wellbeing, and how these can be reconciled with challenges such as reducing our carbon footprint, adapting new mobility technologies, and improving the quality of our journeys. The book shows how our travel choices are shaped by a wide range of social, physical, psychological and cultural factors, which have profound implications for the design of future transport policies. Offering thought-provoking and practical new perspectives, this fascinating book will be essential for all those who have ever wondered why we travel and how it relates to our fundamental needs
Weighing evidence and assessing uncertainties
In: EFSA journal, Band 14
ISSN: 1831-4732
Maternal cell phone use during pregnancy and child behavioral problems in five birth cohorts
INTRODUCTION: Previous studies have reported associations between prenatal cell phone use and child behavioral problems, but findings have been inconsistent and based on retrospective assessment of cell phone use. This study aimed to assess this association in a multi-national analysis, using data from three cohorts with prospective data on prenatal cell phone use, together with previously published data from two cohorts with retrospectively collected cell phone use data. METHODS: We used individual participant data from 83,884 mother-child pairs in the five cohorts from Denmark (1996-2002), Korea (2006-2011), the Netherlands (2003-2004), Norway (2004-2008), and Spain (2003-2008). We categorized cell phone use into none, low, medium, and high, based on frequency of calls during pregnancy reported by the mothers. Child behavioral problems (reported by mothers using the Strengths and Difficulties Questionnaire or Child Behavior Checklist) were classified in the borderline/clinical and clinical ranges using validated cut-offs in children aged 5-7years. Cohort specific risk estimates were meta-analyzed. RESULTS: Overall, 38.8% of mothers, mostly from the Danish cohort, reported no cell phone use during pregnancy and these mothers were less likely to have a child with overall behavioral, hyperactivity/inattention or emotional problems. Evidence for a trend of increasing risk of child behavioral problems through the maternal cell phone use categories was observed for hyperactivity/inattention problems (OR for problems in the clinical range: 1.11, 95%CI 1.01, 1.22; 1.28, 95%CI 1.12, 1.48, among children of medium and high users, respectively). This association was fairly consistent across cohorts and between cohorts with retrospectively and prospectively collected cell phone use data. CONCLUSIONS: Maternal cell phone use during pregnancy may be associated with an increased risk for behavioral problems, particularly hyperactivity/inattention problems, in the offspring. The interpretation of these results is unclear as uncontrolled confounding may influence both maternal cell phone use and child behavioral problems. ; This work was supported by the European Union: GERoNiMO project (grant 603794) and grants FP7-ENV-2011, 282957, HEALTH.2010.2.4.5-1
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Presence of free gossypol in whole cottonseed
In: EFSA journal, Band 15, Heft 7
ISSN: 1831-4732
Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: The European prospective mother-child study (NewGeneris)
Background: Acrylamide is a common dietary exposure that crosses the human placenta. It is classified as a probable human carcinogen, and developmental toxicity has been observed in rodents. Objectives: We examined the associations between prenatal exposure to acrylamide and birth outcomes in a prospective European mother–child study. Methods: Hemoglobin (Hb) adducts of acrylamide and its metabolite glycidamide were measured in cord blood (reflecting cumulated exposure in the last months of pregnancy) from 1,101 singleton pregnant women recruited in Denmark, England, Greece, Norway, and Spain during 2006–2010. Maternal diet was estimated through food-frequency questionnaires. Results: Both acrylamide and glycidamide Hb adducts were associated with a statistically significant reduction in birth weight and head circumference. The estimated difference in birth weight for infants in the highest versus lowest quartile of acrylamide Hb adduct levels after adjusting for gestational age and country was –132 g (95% CI: –207, –56); the corresponding difference for head circumference was –0.33 cm (95% CI: –0.61, –0.06). Findings were similar in infants of nonsmokers, were consistent across countries, and remained after adjustment for factors associated with reduced birth weight. Maternal consumption of foods rich in acrylamide, such as fried potatoes, was associated with cord blood acrylamide adduct levels and with reduced birth weight. Conclusions: Dietary exposure to acrylamide was associated with reduced birth weight and head circumference. Consumption of specific foods during pregnancy was associated with higher acrylamide exposure in utero. If confirmed, these findings suggest that dietary intake of acrylamide should be reduced among pregnant women. ; The NewGeneris (Newborns and Genotoxic exposure risks) study was funded by the European Union (EU Contract FOOD-CT-2005-016320). The study was also supported by grants obtained locally, including the Swedish Cancer and Allergy Foundation and the Swedish Research Council Formas, the National Institute for Health Research, UK (programme grant RP-PG-0407-10044), the Norwegian Ministry of Health, the Norwegian Ministry of Education and Research, the Norwegian Research Council/FUGE (grant 151918/S10), the EU funded HiWATE (contract Food-CT-2006-036224), the U.S. National Institutes of Health (NIH)/National Institute of Environmental Health Sciences (contract NO-ES-75558), and the U.S. NIH/National Institute of Neurological Disorders and Stroke (grant 1 UO1 NS 047537-01). M.P. holds a Juan de la Cierva postdoctoral fellowship awarded from the Spanish Ministry of Science and Innovation (JCI-2011-09479)
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Update of the risk assessment of mineral oil hydrocarbons in food
In: EFSA journal, Band 21, Heft 9
ISSN: 1831-4732
Risk assessment of ochratoxin A in food
In: EFSA journal, Band 18, Heft 5
ISSN: 1831-4732
Scientific Opinion on Flavouring Group Evaluation 215 Revision 1 (FGE.215Rev1): seven α,β‐unsaturated cinnamyl ketones from subgroup 3.2 of FGE.19
In: EFSA journal, Band 17, Heft 11
ISSN: 1831-4732
Assessment of a decontamination process for dioxins and PCBs from fish meal by replacement of fish oil
In: EFSA journal, Band 16, Heft 2
ISSN: 1831-4732
Assessment of the application for renewal of authorisation of VevoVitall® (benzoic acid) as feed additive for weaned piglets and pigs for fattening
In: EFSA journal, Band 15, Heft 12
ISSN: 1831-4732