Suchergebnisse

The asthma obstructive sleep apnea overlap is a clinical entity relatively new and the association with a dysfunctional plasma lipid profile is not known. Aim. In this study, we compared the serum lipid profile in asthma-obstructive sleep apnea overlap syndrome to those in asthma and obstructive sleep apnea patients. Methods. A cross-sectional study of 97 cases of which 26 patients had only asthma, 51 were diagnosed with OSA, and 20 were identified with A-OSA overlap. The lipid profile included the total cholesterol, HDL-cholesterol, triglycerides, the LDLcholesterol. The Casteli indexes I and II and the atherogenic plasma index were calculated. Results. The patients with asthma- obstructive apnea overlap were older (55.55 years vs 53,73 years in obstructive sleep apnea and 51,04 years in asthmatics), mostly obese (95%), and had a significantly higher average of BMI (38.11 vs. 35.64 and 28.8, respectively). Asthma- obstructive apnea overlap was at higher risk of cardiovascular disease than asthmatics, in respect to the lipid profile: the levels of HDL-cholesterol were lower, triglycerides were higher, and the values of Castelli index I and II were higher. Conclusions. Based on our results, we confirm that age and BMI contribute to the risk of A-OSA overlap. The major differences in the common markers of the serum lipid profile are lower HDL-C and higher triglycerides. As a clinical implication, both Castelli indexes could provide additional value for cardiovascular risk and should be monitored in A-OSA overlap.

[EN] Early services for ASD need to canvas the opinions of both parents and professionals. These opinions are seldom compared in the same research study. This study aims to ascertain the views of families and professionals on early detection, diagnosis and intervention services for young children with ASD. An online survey compiled and analysed data from 2032 respondents across 14 European countries (60.9% were parents; 39.1% professionals). Using an ordinal scale from 1 to 7, parents' opinions were more negative (mean = 4.6; SD 2.2) compared to those of professionals (mean = 4.9; SD 1.5) when reporting satisfaction with services. The results suggest services should take into account child's age, delays in accessing services, and active stakeholders' participation when looking to improve services.

Early services for ASD need to canvas the opinions of both parents and professionals. These opinions are seldom compared in the same research study. This study aims to ascertain the views of families and professionals on early detection, diagnosis and intervention services for young children with ASD. An online survey compiled and analysed data from 2032 respondents across 14 European countries (60.9% were parents; 39.1% professionals). Using an ordinal scale from 1 to 7, parents' opinions were more negative (mean = 4.6; SD 2.2) compared to those of professionals (mean = 4.9; SD 1.5) when reporting satisfaction with services. The results suggest services should take into account child's age, delays in accessing services, and active stakeholders' participation when looking to improve services.

Abstract Early services for ASD need to canvas the opinions of both parents and professionals. These opinions are seldom compared in the same research study. This study aims to ascertain the views of families and professionals on early detection, diagnosis and intervention services for young children with ASD. An online survey compiled and analysed data from 2032 respondents across 14 European countries (60.9% were parents; 39.1% professionals). Using an ordinal scale from 1 to 7, parents' opinions were more negative (mean = 4.6; SD 2.2) compared to those of professionals (mean = 4.9; SD 1.5) when reporting satisfaction with services. The results suggest services should take into account child's age, delays in accessing services, and active stakeholders' participation when looking to improve services.