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Worldviews consist of preconceptions about the nature of mind, knowledge, and meaning, and these assumptions influence theorizing about human development and the interpretation of research. We outline two contrasting worldviews - dualist versus relational - and explicate the implications of such preconceptions for studying the development of pointing gestures. Pointing is a pivotal social skill that is an aspect of social understanding, as well as a foundational form of interaction for language. In studying the development of pointing it is possible to observe how infants develop the social skills required to convey meaning in human ways. Thus, this is an area in which to examine the nature and development of meaning, and an adequate conception of meaning is necessary for theories of language and cognition. We argue that dualist approaches have problems that can be avoided by adopting a relational worldview and the relational developmental systems framework that follows from it, which we suggest is a fruitful approach to theorizing about human development.