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AbstractThis paper bridges the gap between studies of subaltern social movements and elite politics by asking how political and economic elites respond to indigenous mobilisation in Ecuador. I argue that elites have developed a hegemonic project based around three core principles – multiculturalism, economic liberalism and democracy – that serves to incorporate indigenous peoples into the political system while simultaneously excluding indigenous movement demands that would undermine the political and economic sources of elite power. The paper develops this argument around a concept of what I call 'multicultural market democracy' based on historical analysis and in-depth interviews with 43 Ecuadorian elites.

Over the past decade, there has been a surge of "new Left" governments in Latin America, yet polling data shows no comparable shift to the left among the general Latin American population. If electorates have not followed their political leaders to the left, then it is likely that new right- wing political actors will emerge to compensate for the leftward shift in Latin American politics. I propose a research agenda for studying right-wing politics in light of the current wave of left-leaning governments in the region. I argue that we should focus on four main areas of right-wing politics: the political agenda of right-wing groups; their political organization; their power capability; and the institutional environment in which they operate. This agenda requires that we move beyond the traditional focus on right- wing political parties and focus on right-wing organizations at all levels of formal politics, as well as groups that operate outside the formal political arena. Adapted from the source document.

Over the past decade, there has been a surge of "new Left" governments in Latin America, yet polling data shows no comparable shift to the left among the general Latin American population. If electorates have not followed their political leaders to the left, then it is likely that new right-wing political actors will emerge to compensate for the leftward shift in Latin American politics. The author proposes a research agenda for studying right-wing politics in light of the current wave of left-leaning governments in the region. He argues that we should focus on four main areas of right-wing politics: the political agenda of right-wing groups; their political organization; their power capability; and the institutional environment in which they operate. This agenda requires that we move beyond the traditional focus on right-wing political parties and focus on right-wing organizations at all levels of formal politics, as well as groups that operate outside the formal political arena. (GIGA)

Ecuadorians have gone to the polls six times since 2006: to elect a president and a legislature, for a second round of that presidential election, to decide whether to hold a constitutional assembly (which they did), to elect delegates to that assembly, to ratify the new constitution (which they also did), and finally in April 2009 to elect a president, vice president, and unicameral legislature under the rules of the new constitution. The 2009 election represents the culmination of President Rafael Correa's attempt to sideline Ecuador's traditional political parties and remake the country's institutional apparatus in ways that further his "Citizens' Revolution" which, among other things, seeks to reduce Ecuador's gaping socioeconomic inequalities. [Copyright Elsevier Ltd.]

Ecuadorians have gone to the polls six times since 2006: to elect a president and a legislature, for a second round of that presidential election, to decide whether to hold a constitutional assembly (which they did), to elect delegates to that assembly, to ratify the new constitution (which they also did), and finally in April 2009 to elect a president, vice president, and unicameral legislature under the rules of the new constitution. The 2009 election represents the culmination of President Rafael Correa's attempt to sideline Ecuador's traditional political parties and remake the country's institutional apparatus in ways that further his "Citizens' Revolution" which, among other things, seeks to reduce Ecuador's gaping socioeconomic inequalities. [Copyright Elsevier Ltd.]

ImportanceOne major advantage of developing large, federally funded networks for clinical research in neurology is the ability to have a trial-ready network that can efficiently conduct scientifically rigorous projects to improve the health of people with neurologic disorders.ObservationsNational Institute of Neurological Disorders and Stroke Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) was established in 2011 and renewed in 2018 with the goal of being an efficient network to test between 5 and 7 promising new agents in phase II clinical trials. A clinical coordinating center, data coordinating center, and 25 sites were competitively chosen. Common infrastructure was developed to accelerate timelines for clinical trials, including central institutional review board (a first for the National Institute of Neurological Disorders and Stroke), master clinical trial agreements, the use of common data elements, and experienced research sites and coordination centers. During the first 7 years, the network exceeded the goal of conducting 5 to 7 studies, with 9 funded. High interest was evident by receipt of 148 initial applications for potential studies in various neurologic disorders. Across the first 8 studies (the ninth study was funded at end of initial funding period), the central institutional review board approved the initial protocol in a mean (SD) of 59 (21) days, and additional sites were added a mean (SD) of 22 (18) days after submission. The median time from central institutional review board approval to first site activation was 47.5 days (mean, 102.1; range, 1-282) and from first site activation to first participant consent was 27 days (mean, 37.5; range, 0-96). The median time for database readiness was 3.5 months (mean, 4.0; range, 0-8) from funding receipt. In the 4 completed studies, enrollment met or exceeded expectations with 96% overall data accuracy across all sites. Nine peer-reviewed manuscripts were published, and 22 oral presentations or posters and 9 invited presentations were given at regional, national, and international meetings.Conclusions and relevanceNeuroNEXT initiated 8 studies, successfully enrolled participants at or ahead of schedule, collected high-quality data, published primary results in high-impact journals, and provided mentorship, expert statistical, and trial management support to several new investigators. Partnerships were successfully created between government, academia, industry, foundations, and patient advocacy groups. Clinical trial consortia can efficiently and successfully address a range of important neurologic research and therapeutic questions.