Suchergebnisse

Making Sense of War provides a comprehensive and clear analysis of the complex business of waging war. It gives readers a thorough understanding of the key concepts in strategic thought, concepts that have endured since the Athenian general Thucydides and the Chinese philosopher/warrior Sun Tzu first wrote about strategy some 2500 years ago. It also examines the influence on strategic choice and military strategy of political, legal and technological change. This book discusses strategy at every level of competition, employing a thematic approach and using historical examples from 500 BCE to the present. It discusses the contraints and opportunities facing military commanders in the 21st century, and demonstrates that the formulation of military strategy will continue to be perhaps the single most important responsibility for senior security officials. Making Sense of War offers original insights into the imperatives of military success in the era of asymmetric warfare

Hydropower is an increasingly popular source of renewable and 'green' (in terms of emissions) energy, but reduced longitudinal connectivity and diverting flow through turbines can have negative impacts on catadromous anguillid eel species that have declined globally. There is an urgent need for environmental managers to perform remediation actions, such as protecting flows for migratory fish and providing passage solutions at infrastructure, under increasing legislative pressure. To deliver this, a more comprehensive understanding of eel migration in catchments with hydropower is required. Here, we illustrate the importance of catchment-wide and fine-scale acoustic telemetry, coupled with the influence of eel maturation (i.e. sex steroid levels), to determine the impact of Wairua run-of-river Power Station (WPS) on downstream migrating shortfin eels (Anguilla australis; n = 25) in Wairua River, New Zealand. Migration speed through the unregulated reach upstream of WPS was positively correlated with flow, but not eel length or sex steroids. Three eels passed a diversion weir (DW) to follow the natural watercourse and eight entered the WPS canal. Eels predominantly entered (95.2%) and were last detected (85.7%) in WPS forebay during hours of darkness. Eleven (52%) of the 21 eels that entered WPS forebay were impinged or entrained, all when three or four turbines were in operation (power generation >3.04 MW). Ten (48%) passed WPS spillway during significantly higher spill than impinged or entrained eels, with four passing during no turbine operation, after experiencing high flows near the intake (multiple receivers in WPS forebay used to quantify fine-scale behaviour). On average, eels were impinged or entrained at WPS significantly quicker (6.40 ± 11.13 days) than eels that entered the spillway (25.17 ± 15.12 days), but eel length and sex steroids did not significantly influence fate. Of the eels that migrated through the entire 55 km study reach, passage time at DW and WPS equated to 0.01–0.02% and ...

Making Sense of War provides a comprehensive and clear analysis of the complex business of waging war. It gives readers a thorough understanding of the key concepts in strategic thought, concepts that have endured since the Athenian general Thucydides and the Chinese philosopher/warrior Sun Tzu first wrote about strategy some 2500 years ago. It also examines the influence on strategic choice and military strategy of political, legal and technological change. This book discusses strategy at every level of competition, employing a thematic approach and using historical examples from 500 BCE to the present. It discusses the contraints and opportunities facing military commanders in the 21st century, and demonstrates that the formulation of military strategy will continue to be perhaps the single most important responsibility for senior security officials. Making Sense of War offers original insights into the imperatives of military success in the era of asymmetric warfare

Aquaglyceroporin-2 is a known determinant of melarsoprol-pentamidine cross-resistance in Trypanosoma brucei brucei laboratory strains. Recently, chimerization at the AQP2-AQP3 tandem locus was described from melarsoprol-pentamidine cross-resistant Trypanosoma brucei gambiense isolates from sleeping sickness patients in the Democratic Republic of the Congo. Here, we demonstrate that reintroduction of wild-type AQP2 into one of these isolates fully restores drug susceptibility while expression of the chimeric AQP2/3 gene in aqp2-aqp3 null T. b. brucei does not. This proves that AQP2-AQP3 chimerization is the cause of melarsoprol-pentamidine cross-resistance in the T. b. gambiense isolates.

Aquaglyceroporin-2 is a known determinant of melarsoprol–pentamidine cross-resistance in Trypanosoma brucei brucei laboratory strains. Recently, chimerization at the AQP2–AQP3 tandem locus was described from melarsoprol–pentamidine cross-resistant Trypanosoma brucei gambiense isolates from sleeping sickness patients in the Democratic Republic of the Congo. Here, we demonstrate that reintroduction of wild-type AQP2 into one of these isolates fully restores drug susceptibility while expression of the chimeric AQP2/3 gene in aqp2–aqp3 null T. b. brucei does not. This proves that AQP2–AQP3 chimerization is the cause of melarsoprol–pentamidine cross-resistance in the T. b. gambiense isolates.

Baker, N. ; Sebastain, L. C.: The problem with parachuting: strategic studies and security in the Asia/Pacific region. - S.15-31. ... Chan, S.: Regime transition in the Asia/Pacific region: democratization as a double-edged sword. - S.52-67. ... Acharya, A.: A regional security community in Southeast Asia? - S.175-200. Evans, P. M.: The prospects for multilateral security co-operation in the Asia/Pacific region. - S.201-217. Morimoto, S.: A security framework for the Asia/Pacific region. - S.218-231