Suchergebnisse

Cover -- Occhiello -- Dedica -- Indice -- Introduzione -- 1. Riconoscimento dei diritti e protezione rafforzata dei minori -- 2. Le fonti sovranazionali nella anticipazione della tutela del minorenne -- 3. Delitti di pedo-pornografia e recenti interpretazioni giurisprudenziali -- 4. Indagine comparatistica -- 5. Riflessioni sul valore del consenso del minore -- 6. Il possesso di pornografia minorile reale e virtuale -- 7. Diffusione non consentita dell'immagine sessuale realizzata con il consenso -- Sintesi conclusiva -- Bibliografia -- Volumi pubblicati.

International audience ; We introduce digital groundwater data and information products of the four recently completed GeoERA groundwater projects in support of integrated and sustainable management of European water resources under climate and global change. The four projects HOVER, TACTIC, RESOURCE and VOGERA were respectively mainly related to groundwater quality, climate change impact and recharge, groundwater availability and vulnerability of shallow groundwater resources to deep sub-surface energy related activities. The strength of these projects was to combine the expertise on geology and hydrogeology and data on groundwater quality and quantity including a high variability of hydrogeological context. The main impacts and services of the four GeoERA groundwater projects can be summarized as follows: - Improved access to downloadable groundwater quantity and quality data at local to Pan European scale - State-of-the-art tools to support sustainable decision making in relation to the water-food-energyecosystem nexus - Tools for assessment of climate change impacts, mitigation and adaptation strategies, drought and flood risks etc. - Opportunities for private companies and research institutions to collaborate and develop new groundwater add on services to EGDI The data and tools are freely accessible and downloadable from the European subsurface information platform (the European Geological Data Infrastructure, EGDI). The information products are important contributions to support implementation of UN and EU policies including the UN Sustainable Development Goals (SDG) and the European Water Framework and Groundwater directives. We will present a few examples of the maps and information build during the project as a direct contribution to the evaluation of the current and future status of European groundwater quantity and quality at regional to Pan-European scale.

International audience ; We introduce digital groundwater data and information products of the four recently completed GeoERA groundwater projects in support of integrated and sustainable management of European water resources under climate and global change. The four projects HOVER, TACTIC, RESOURCE and VOGERA were respectively mainly related to groundwater quality, climate change impact and recharge, groundwater availability and vulnerability of shallow groundwater resources to deep sub-surface energy related activities. The strength of these projects was to combine the expertise on geology and hydrogeology and data on groundwater quality and quantity including a high variability of hydrogeological context. The main impacts and services of the four GeoERA groundwater projects can be summarized as follows: - Improved access to downloadable groundwater quantity and quality data at local to Pan European scale - State-of-the-art tools to support sustainable decision making in relation to the water-food-energyecosystem nexus - Tools for assessment of climate change impacts, mitigation and adaptation strategies, drought and flood risks etc. - Opportunities for private companies and research institutions to collaborate and develop new groundwater add on services to EGDI The data and tools are freely accessible and downloadable from the European subsurface information platform (the European Geological Data Infrastructure, EGDI). The information products are important contributions to support implementation of UN and EU policies including the UN Sustainable Development Goals (SDG) and the European Water Framework and Groundwater directives. We will present a few examples of the maps and information build during the project as a direct contribution to the evaluation of the current and future status of European groundwater quantity and quality at regional to Pan-European scale.

International audience ; We introduce digital groundwater data and information products of the four recently completed GeoERA groundwater projects in support of integrated and sustainable management of European water resources under climate and global change. The four projects HOVER, TACTIC, RESOURCE and VOGERA were respectively mainly related to groundwater quality, climate change impact and recharge, groundwater availability and vulnerability of shallow groundwater resources to deep sub-surface energy related activities. The strength of these projects was to combine the expertise on geology and hydrogeology and data on groundwater quality and quantity including a high variability of hydrogeological context. The main impacts and services of the four GeoERA groundwater projects can be summarized as follows: - Improved access to downloadable groundwater quantity and quality data at local to Pan European scale - State-of-the-art tools to support sustainable decision making in relation to the water-food-energyecosystem nexus - Tools for assessment of climate change impacts, mitigation and adaptation strategies, drought and flood risks etc. - Opportunities for private companies and research institutions to collaborate and develop new groundwater add on services to EGDI The data and tools are freely accessible and downloadable from the European subsurface information platform (the European Geological Data Infrastructure, EGDI). The information products are important contributions to support implementation of UN and EU policies including the UN Sustainable Development Goals (SDG) and the European Water Framework and Groundwater directives. We will present a few examples of the maps and information build during the project as a direct contribution to the evaluation of the current and future status of European groundwater quantity and quality at regional to Pan-European scale.

Abstract Environmental legislations are currently imposing important restrictions to regulate the use of refrigerant fluids in order to reduce the greenhouse gases emissions and global warming potential. To overcome these issues, a valid alternative to replace conventional refrigeration systems can be represented by magnetic refrigeration. Since magnetic refrigeration is based on the magnetocaloric effect it represents an environmental friendly technology that avoids the use of Chlorinated refrigerants. In this paper a preliminary analysis of a novel magnetocaloric refrigerator is presented. The magnetocaloric refrigeration prototype uses Gadolinium as refrigerant and water as heat exchange medium, and relies on permanent magnets as magnetic field source. The device operates according to the active regenerative principle with a rotary movement. A detailed description of the main components included in the design of the prototype device is presented along with a schematic representation of the hydraulic circuit. Focusing on the regenerators beds, some simulations have been carried out to quantify the heat energy fluxes between water and gadolinium. The results of the simulations show a decrease on gadolinium temperature distribution cycle by cycle highlighting the actual effect of the regeneration.

BackgroundAutoimmune disease is one of the leading causes of morbidity and mortality worldwide. In Addisons disease, the adrenal glands are targeted by destructive autoimmunity. Despite being the most common cause of primary adrenal failure, little is known about its aetiology. MethodsTo understand the genetic background of Addisons disease, we utilized the extensively characterized patients of the Swedish Addison Registry. We developed an extended exome capture array comprising a selected set of 1853 genes and their potential regulatory elements, for the purpose of sequencing 479 patients with Addisons disease and 1394 controls. ResultsWe identified BACH2 (rs62408233-A, OR = 2.01 (1.71-2.37), P = 1.66 x 10(-15), MAF 0.46/0.29 in cases/controls) as a novel gene associated with Addisons disease development. We also confirmed the previously known associations with the HLA complex. ConclusionWhilst BACH2 has been previously reported to associate with organ-specific autoimmune diseases co-inherited with Addisons disease, we have identified BACH2 as a major risk locus in Addisons disease, independent of concomitant autoimmune diseases. Our results may enable future research towards preventive disease treatment. ; Funding Agencies|Swedish Research Council; Torsten Foundation; Ragnar Soderberg Foundation; European Union [201167]; Stockholm County Council; Karolinska Institutet; Swedish Society for Medical Research; Swedish Society of Medicine; NovoNordisk Foundation; Tore Nilsons Foundation for Medical Research; Swedish Research Council Formas; Knut and Alice Wallenberg Foundation; Marianne and Marcus Wallenberg Foundation; Swedish Reumatism Foundation; King Gustaf Vs 80-year Foundation; Ake Wiberg Foundation; AstraZeneca Science for Life Laboratory Research Collaboration grant (DIS-SECT)