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Preface -- Contents -- Personalized Medicine: The Path to New Medicine -- 1 Introduction -- 2 Definition and Elements of Personalized Medicine -- 3 Difference Between Traditional and Personalized Medicine -- 4 What Personalized Medicine Has to Offer? -- 5 Influence of Personalized Medicine on Participants -- 6 Technological and Infrastructural Presumptions -- 7 The Impact of Personalized Medicine and Implementation -- 8 Personalized Preventive Medicine and Diet -- 9 Studies Indispensable for the Development of Personalized Medicine

Whether or not we can call Uber's business model as disruptive innovation (admittedly, according to the author of the disruptive innovation theory, we cannot), the fact remains that it has shaken the traditional models of passenger transport industries around the world. The law does not respond well, or, better said, it is not able to react fast enough to innovations. Technological and business inventions represent a threat to legal certainty. When an innovative business model, facilitated by the use of new technologies occurs, it is usually associated with a whole array of legal issues and conundrums. The law will try desperately to fit it into the existing moulds of legal regulation. The recent Uber Spain judgment (EU:C:987:2017) by the Court of Justice of the European Union (CJEU) provides a perfect illustration for this. According to the CJEU, Uber is a transport company. This paper will analyse the arguments presented in the judgment to show how law is not able to deal with rapid technological and societal changes in today's digital world. The implications of this judgment are far reaching, not just for Uber's operations in the EU and world-wide, but also for other game changers in the digital economy.

This book explores the reactions to Europeanization and globalization in times of economic distress, including the transformation of European values in national legal cultures. The authors explore how European values, tradition and new legal challenges interconnect and dictate the paths of transition between old and new Europe. The first chapter starts with a question: can Roman Legal Tradition play a role of identity factor towards a New Europe? Can it be considered as a general value identifying new Europe, built on a minimum core of principles - persona, dominum, obligation, contract and inheritance - composing the whole European private law tradition? Subsequent chapters attempt to provide possible responses to the question: what is Europe today? The answers diverge, depending on the research area. The inherent dichotomy of human rights protection in Europe and the concept of 'one law, one court' are investigated in the second chapter, whereas the third chapter focuses on asylum and the interrelation and interdependence of the Court of Justice of the EU and the European Court of Human Rights. The next three chapters concentrate on matters of equal treatment and non-discrimination. The first contribution in this part reflects on the crisis and methodological and conceptual issues faced by modern anti-discrimination law. It is followed by a specific analysis of the empowerment of women or gender-balancing in company boards. The third contribution reveals the impact of the Croatian anti-discrimination law on private law relations. The next chapter deals with the issue of social rights in Croatia and the method of their regulation in the context of the new European values. The immense challenges posed by the market integration imperative and democratic transition have brought about different reactions in the national legal systems and legal cultures of both old and new Member States. As such, Europe has effectively been reunited, but what about the convergence of national legal cultures? This is the focal point of the remaining chapters, which focus on various issues, from internal market, competition law, consumer welfare, liberalization of network industries to the EU capital market. The magnitude of EU activity in these areas offers conclusive evidence that old and new paradigms are evolving and shaping the future of the EU.

Sloboda pružanja usluga kao jedna od temeljnih gospodarskih sloboda omogućava svakom državljaninu države članice s poslovnim nastanom u državi članici EU-a da može pružati usluge u drugoj državi članici bez ograničenja i pod istim uvjetima kao i državljani te države članice. Sve veća specijalizacija u pojedinim profesijama i razvoj novih tehnologija i modela pružanja usluga donose nove izazove i kontinuirano nameću potrebu preispitivanja usklađenosti nacionalnih zakonodavstava s propisima koji reguliraju unutarnje tržište. Posebno je teško pomiriti različite pravne kulture država članica, koje polaze od vlastitih vrijednosti i pretpostavaka kako regulirati pojedine djelatnosti i pružanje usluga. Neki sektori otporniji su na liberalizaciju i oslanjaju se na tradicionalno protekcionističke propise država članica. Sve veći obujam usluga i sve veća specijalizacija povećavaju broj i razinu profesionalnih aktivnosti koje reguliraju države, regulatorna tijela ili se pak primjenjuje kombinacija tih dvaju načina reguliranja. Osim odredaba Ugovora o funkcioniranju Europske unije jedinstveni europski okvir za pružanje usluga čine brojni sekundarni pravni izvori koji imaju cilj olakšati djelovanje slobode pružanja usluga, uspostaviti zajednička pravila i olakšati administrativnu suradnju. U tom je smislu najvažnija Direktiva 2006/123/EZ o uslugama o unutarnjem tržištu koja je Zakonom o uslugama iz 2011. godine implementirana u hrvatsko zakonodavstvo. Zakonom se nastoji pružateljima usluga olakšati ostvarivanje slobode poslovnog nastana te slobodno kretanje usluga uz istodobno održavanje visoka stupnja kvalitete tih usluga. Od država članica zahtijeva se stalno uklanjanje prepreka slobodi pružanja usluga u nizu djelatnosti te se tako u Republici Hrvatskoj kontinuirano provodi liberalizacija tržišta usluga raznim administrativnim i poreznim rasterećenjima, ali i promjenom raznih sektorskih propisa koji imaju utjecaj na funkcioniranje slobode poslovnog nastana i slobode pružanja usluga. Temeljna načela liberalizacije tržišta ...

Part I -- Introduction -- Options for Realising and Financing Innovation in the German Healthcare System -- Clinical Evaluation of Medical Devices in Europe -- Personalized Medicine: Cutting Edge Developments -- Part II -- Methodological and Technological Aspects Important for Personalised Medicine -- Nanotechnology Approaches for Autologous Stem Cell Manipulation in Personalized Regenerative Medicine -- Patient–Doctor Relationship: Data Protection in the Context of Personalised Medicine -- High-Throughput Analytics in the Function of Personalized Medicine -- Bacteria—Human Interactions: Leads for Personalized Medicine -- Present and Future in Personalized Clinical and Laboratory Approaches to In Vitro Fertilization Procedures. -- Microbiota: Novel Gateway Towards Personalised Medicine -- The Right Not to Know in the Context of Genetic Testing -- Part III -- Social and Humanistic Aspects of Personal Medicine -- Personalized Medicine, Justice and Equality -- Evolution Paths of Business Models in Personalized Medicine -- Socio-Humanistic and Political Context of Personalized Medicine -- Personalized Medicine and Personalized Pricing: Degrees of Price Discrimination -- Personalised Medicine in Health Care Systems and EU Law: The Role of Solidarity?. Personalizing Privacy? Examining the Shifting Boundaries of a Fundamental Right in Preimplantation Genetic Testing of Embryos -- (Bio)ethical Aspects of Personalised Medicine: Revealing an "Inconvenient Truth"? -- Patient-Physician Relationship in Personalized Medicine -- Barriers Towards New Medicine: Personalized and Integrative Medicine Concepts -- The Reverse Payment Settlements in the European Pharmaceutical Market -- Doping in Sports: Legal and Other Aspects -- Personalised Medicine in Public Healthcare Systems -- Part IV -- Clinical Aspects of Personalised Medicine -- Targeted Breast Cancer Therapy -- Personalized Medicine in Ophthalmology: Treatment of Total Limbal Stem Cell Deficiency with Autologous Ex Vivo Cultivated Limbal Epithelial Stem Cell Graft -- Personalized Total Knee Arthroplasty: Better Fit for Better Function -- Comprehensive Approach to Personalized Medicine into Chronic Musculoskeletal Diseases -- Circadian Rhythms and Personalized Melanoma Therapy -- Genetic and Epigenetic Profiling in Personalized Medicine: Advances in Treatment of Acute Myeloid Leukemia -- The Future of Cartilage Repair

Flexicurity is used as a strategy in the Netherlands in order to increase flexibility for the permanent workers and improve the position of the flexible workers. The concept was introduced in the 1990s by the government in a paper and was further elaborated in an agreement of both sides of industry. This involved that the position of temporary agency workers was regulated and improved, and it was made easier to provide contracts for a definite period. This agreement was laid down in an act, thus amending the existing labour code. Important was that the position of the trade unions was reinforced since the Act allowed deviation from the general rules only by a collective labour agreement. In 2013, again the social partners were asked to negotiate on the flexibilisation of dismissal law and improving the position of flexible workers. This led to an agreement of the social partners and was subsequently laid down in the labour code. This procedure is relatively successful but leaves some dilemmas untouched, such as it is easier for employers to make use of the flexibilisation of the position of permanent workers than for flexible workers to make use of the rules that are meant as an improvement. Most of them can be escaped, e.g., by employing the workers shorter than the threshold for improving their position. This may sometimes even mean that flexible workers are worse off since they lose their work sooner than they did under the old rules.