Suchergebnisse

AbstractCan the development of the regional digital economy improve the productivity of enterprises and thus contribute to the enhancement of the local economy? To address this question, we employ listed companies operating in the Yangtze River Delta of China from 2007 to 2017 as a case study. The digital economy here refers to the comprehensive combination of digital industrialization and industrial digitalization. First, we find that the development of the regional digital economy has a significant positive effect on the productivity of enterprises. Second, there are three possible paths to improve enterprise productivity: management cost upgrading, capacity of innovation upgrading, and factor input structure upgrading. The empirical results reveal that management cost upgrading suppresses the development of the regional digital economy, that is, the lagged indirect effects of innovation activities or the increased labour costs required by innovation activities crowd out capital from factor inputs. However, if these management costs can be significantly reduced, the development of the regional digital economy increases enterprise productivity.

Tao Han,1,* Jianjun Chen,1,* Yuting Luan,2,* Xiaoxia Chen,1,* Xiaodan Yang,1 Yue Zhang,1 Gao Li,2 Di Wang,3 Zhendong Zheng1 1Department of Oncology, Cancer Center of People's Liberation Army, General Hospital of Shenyang Military Region, Shenyang 110840, People's Republic of China; 2Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang 110840, People's Republic of China; 3Department of Pathology, General Hospital of Shenyang Military Region, Shenyang 110840, People's Republic of China *These authors contributed equally to this work Abstract: Embryonal rhabdomyosarcoma (ERMS) has a low prevalence, poor prognosis, and limited treatment efficacy. We report a case of an 18-year-old male whose disease relapsed in the abdominal cavity after a testicular ERMS curative resection. The patient received eight sequential cycles of rescue therapy using cisplatin and isocyclophosphamide in combination with a vascular targeted drug, Endostar. The therapeutic effect of the combination regimen has been evaluated for complete response. This is the first case to report using Endostar and chemotherapy in relapsed ERMS, and the curative effect results in complete response. Endostar, a new vascular targeted drug, combined with chemotherapy may play a synergistic role and provide a reference for the treatment of ERMS. Keywords: embryonal rhabdomyosarcoma, metastasis, complete response, endogenous angiogenesis inhibitor