Suchergebnisse

Throughout the 1950s China implemented a code of laws, regulations and programmes whose effect was formally to differentiate residential groups as a means to control population movement and mobility and to shape state developmental priorities. Thehukousystem, which emerged in the course of a decade, was integral to the collective transformation of the countryside, to a demographic strategy that restricted urbanization, and to the redefinition of city-countryside and state-society relations. This article offers a documentary study tracing the origins and development of thehukousystem of population registration and control, and scrutinizes its relationship to a host of connected institutions, for clues to understanding distinctive features of China's developmental trajectory and social structure in the era of mobilizational collectivism. It considers the farreaching social consequences of thehukousystem with particular attention to its implications for the creation of spatial hierarchies, especially its consequences for defining the position of villagers in the Chinese social system.

Throughout the 1950s China implemented a code of laws, regulations and programmes whose effect was formally to differentiate residential groups as a means to control population movement and mobility (the hukou system). The article offers a documentary study tracing the origins and development of the hukou system of population registration and control, and scrutinizes its relationship to a host of connected institutions. (DÜI-Sen)

China's hukou and danwei systems; the United Front redefined for the party-state; mechanics of state propaganda; building the party-state in China 1949-1965; politics of an "un-Maoist" interlude, 1956-57; localism, central policy, provincial purges, 1957-58; Shanghai's strike wave of 1957; newly available sources on CCP history form the PRC; interviews on party history; mendacity and veracity in the recent Chinese communist memoir literature; National Defense University's "Teaching reference materials"; researching China's provinces

PubChem's BioAssay database (https://pubchem.ncbi.nlm.nih.gov) has served as a public repository for small-molecule and RNAi screening data since 2004 providing open access of its data content to the community. PubChem accepts data submission from worldwide researchers at academia, industry and government agencies. PubChem also collaborates with other chemical biology database stakeholders with data exchange. With over a decade's development effort, it becomes an important information resource supporting drug discovery and chemical biology research. To facilitate data discovery, PubChem is integrated with all other databases at NCBI. In this work, we provide an update for the PubChem BioAssay database describing several recent development including added sources of research data, redesigned BioAssay record page, new BioAssay classification browser and new features in the Upload system facilitating data sharing.

Abstract
Background
The NORMAN Association (https://www.norman-network.com/) initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/) in 2015, following the NORMAN collaborative trial on non-target screening of environmental water samples by mass spectrometry. Since then, this exchange of information on chemicals that are expected to occur in the environment, along with the accompanying expert knowledge and references, has become a valuable knowledge base for "suspect screening" lists. The NORMAN-SLE now serves as a FAIR (Findable, Accessible, Interoperable, Reusable) chemical information resource worldwide.

Results
The NORMAN-SLE contains 99 separate suspect list collections (as of May 2022) from over 70 contributors around the world, totalling over 100,000 unique substances. The substance classes include per- and polyfluoroalkyl substances (PFAS), pharmaceuticals, pesticides, natural toxins, high production volume substances covered under the European REACH regulation (EC: 1272/2008), priority contaminants of emerging concern (CECs) and regulatory lists from NORMAN partners. Several lists focus on transformation products (TPs) and complex features detected in the environment with various levels of provenance and structural information. Each list is available for separate download. The merged, curated collection is also available as the NORMAN Substance Database (NORMAN SusDat). Both the NORMAN-SLE and NORMAN SusDat are integrated within the NORMAN Database System (NDS). The individual NORMAN-SLE lists receive digital object identifiers (DOIs) and traceable versioning via a Zenodo community (https://zenodo.org/communities/norman-sle), with a total of > 40,000 unique views, > 50,000 unique downloads and 40 citations (May 2022). NORMAN-SLE content is progressively integrated into large open chemical databases such as PubChem (https://pubchem.ncbi.nlm.nih.gov/) and the US EPA's CompTox Chemicals Dashboard (https://comptox.epa.gov/dashboard/), enabling further access to these lists, along with the additional functionality and calculated properties these resources offer. PubChem has also integrated significant annotation content from the NORMAN-SLE, including a classification browser (https://pubchem.ncbi.nlm.nih.gov/classification/#hid=101).

Conclusions
The NORMAN-SLE offers a specialized service for hosting suspect screening lists of relevance for the environmental community in an open, FAIR manner that allows integration with other major chemical resources. These efforts foster the exchange of information between scientists and regulators, supporting the paradigm shift to the "one substance, one assessment" approach. New submissions are welcome via the contacts provided on the NORMAN-SLE website (https://www.norman-network.com/nds/SLE/).