Suchergebnisse

Huntington's Disease is a hereditary disease which is passed from generation to generation through auto-somal dominant tranmission. The transmission is unrelated to the sex of the child and each child of an affected parent has a 50% chance of inheriting the disease or not inheriting the disease. This disease never skips a generation but for those who do not inherit the offending gene (S), then the disease can no longer be transmitted to future generations. The disease usually manifests itself in the late 30's and early 40's years of age, that is, towards the end of the reproductive life of the patient. The average length of time from onset to death is about 15 years and death is usually due to pneumonia or heart disease in a debilitated person.

As part of a larger study, the Lehman Quality of Life Interview (QOLI) was conducted a total of 85 times with 55 clients with serious mental illness. Results revealed widespread adverse objective circumstances (unemployment, poverty and social isolation) despite which most clients rated their satisfaction levels about average (about equally satisfied and dissatisfied). As expected, subjective quality of life indicators were generally better predictors of global well-being (GWB) (itself based on subjective ratings) than were objective indicators. Correlations between objective and subjective indicators were very low and insignificant. Moderate relationships were found between GWB and levels of personal functioning, and changes in levels of personal functioning, as rated by mental health workers. Retests showed that subjective quality of life was relatively stable over intervals of several months. The findings suggest that leisure and social relations would be suitable areas for interventions that might improve clients' quality of life.