Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing. ; (VLID)6065991
Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children.
Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children.
The Future of the Allergists and Specific Immunotherapy (FASIT) workshop provides a regular platform for global experts from academia, allergy clinics, regulatory authorities and industry to review developments in the field of allergen immunotherapy (AIT). The most recent meeting, held in February 2017, had two main themes: advances in AIT and hot topics in AIT from the regulatory point of view. The first theme covered opportunities for personalised AIT, advances in adjuvants and delivery systems, and the development of new molecules and future vaccines for AIT. Key topics in the second part of the meeting were the effects of the enactment of European Directive 2001/83 on the availability of allergens for therapy and diagnosis across the EU, the challenges of conducting Phase III studies in the field, the future role of allergen exposure chambers in AIT-studies, and specific considerations in performing AIT-studies in the paediatric population. Finally, the group highlighted the forthcoming EAACI guidelines and their particular importance for the standardisation of practice in the treatment of allergies. This supplement presents a comprehensive insight into those panel discussions and highlights unmet needs and also possible solutions to them for the future.
In: Bousquet, J., Agache, I., Anto, J. M., Bergmann, K. C., Bachert, C., Annesi-Maesano, I., Bousquet, P. J., D'Amato, G., Demoly, P., De Vries, G., Eller, E., Fokkens, W. J., Fonseca, J., Haahtela, T., Hellings, P. W., Just, J., Keil, T., Klimek, L., Kuna, P., Carlsen, K. C. Lodrup, Moesges, R., Murray, R., Nekam, K., Onorato, G., Papadopoulos, N. G., Samolinski, B., Schmid-Grendelmeier, P., Thibaudon, M., Tomazic, P., Triggiani, M., Valiulis, A., Valovirta, E., Van Eerd, M., Wickman, M., Zuberbier, T. and Sheikh, A. (2017). Google Trends terms reporting rhinitis and related topics differ in European countries. Allergy, 72 (8). S. 1261 - 1267. HOBOKEN: WILEY. ISSN 1398-9995
Google Trends (GT) searches trends of specific queries in Google and reflects the real-life epidemiology of allergic rhinitis. We compared Google Trends terms related to allergy and rhinitis in all European Union countries, Norway and Switzerland from 1 January 2011 to 20 December 2016. The aim was to assesswhether the same terms could be used to report the seasonal variations of allergic diseases. Using the Google Trend 5-year graph, an annual and clear seasonality of queries was found in all countries apart from Cyprus, Estonia, Latvia, Lithuania and Malta. Different terms were found to demonstrate seasonality depending on the country - namely 'hay fever', 'allergy' and 'pollen' - showing cultural differences. A single set of terms cannot be used across all European countries, but allergy seasonality can be compared across Europe providing the above three terms are used. Using longitudinal data in different countries and multiple terms, we identified an awareness-related spike of searches (December 2016).
In: Bousquet , J , Agache , I , Anto , J M , Bergmann , K C , Bachert , C , Annesi-Maesano , I , Bousquet , P J , D'Amato , G , Demoly , P , De Vries , G , Eller , E , Fokkens , W J , Fonseca , J , Haahtela , T , Hellings , P W , Just , J , Keil , T , Klimek , L , Kuna , P , Lodrup Carlsen , K C , Mösges , R , Murray , R , Nekam , K , Onorato , G , Papadopoulos , N G , Samolinski , B , Schmid-Grendelmeier , P , Thibaudon , M , Tomazic , P , Triggiani , M , Valiulis , A , Valovirta , E , van Eerd , M , Wickman , M , Zuberbier , T & Sheikh , A 2017 , ' Google Trends terms reporting rhinitis and related topics differ in European countries ' , Allergy: European Journal of Allergy and Clinical Immunology , vol. 72 , no. 8 , pp. 1261–1266 . https://doi.org/10.1111/all.13137
Google Trends (GT) searches trends of specific queries in Google and reflects the real-life epidemiology of allergic rhinitis. We compared Google Trends terms related to allergy and rhinitis in all European Union countries, Norway and Switzerland from 1 January 2011 to 20 December 2016. The aim was to assess whether the same terms could be used to report the seasonal variations of allergic diseases. Using the Google Trend 5-year graph, an annual and clear seasonality of queries was found in all countries apart from Cyprus, Estonia, Latvia, Lithuania and Malta. Different terms were found to demonstrate seasonality depending on the country - namely 'hay fever', 'allergy' and 'pollen' - showing cultural differences. A single set of terms cannot be used across all European countries, but allergy seasonality can be compared across Europe providing the above three terms are used. Using longitudinal data in different countries and multiple terms, we identified an awareness-related spike of searches (December 2016).
International audience ; A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a~Good Practice focusing on the implementation of multi-sectoral care pathways using emerging technologies with real life data in rhinitis and asthma multi-morbidity. The European Union Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) has developed a checklist of 28 items for the evaluation of Good Practices. SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. A short summary was proposed for each item and 18 experts, all~members of ARIA and SUNFRAIL from 12 countries, assessed the 28 items using a Survey Monkey-based questionnaire. A visual analogue scale (VAS) from 0 (strongly disagree) to 100 (strongly agree) was used. Agreement equal or over 75% was observed for 14 items (50%). MASK is following the JA-CHRODIS recommendations for the evaluation of Good Practices.
International audience ; A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a~Good Practice focusing on the implementation of multi-sectoral care pathways using emerging technologies with real life data in rhinitis and asthma multi-morbidity. The European Union Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) has developed a checklist of 28 items for the evaluation of Good Practices. SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. A short summary was proposed for each item and 18 experts, all~members of ARIA and SUNFRAIL from 12 countries, assessed the 28 items using a Survey Monkey-based questionnaire. A visual analogue scale (VAS) from 0 (strongly disagree) to 100 (strongly agree) was used. Agreement equal or over 75% was observed for 14 items (50%). MASK is following the JA-CHRODIS recommendations for the evaluation of Good Practices.
International audience ; A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a~Good Practice focusing on the implementation of multi-sectoral care pathways using emerging technologies with real life data in rhinitis and asthma multi-morbidity. The European Union Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) has developed a checklist of 28 items for the evaluation of Good Practices. SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. A short summary was proposed for each item and 18 experts, all~members of ARIA and SUNFRAIL from 12 countries, assessed the 28 items using a Survey Monkey-based questionnaire. A visual analogue scale (VAS) from 0 (strongly disagree) to 100 (strongly agree) was used. Agreement equal or over 75% was observed for 14 items (50%). MASK is following the JA-CHRODIS recommendations for the evaluation of Good Practices.
International audience ; A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a~Good Practice focusing on the implementation of multi-sectoral care pathways using emerging technologies with real life data in rhinitis and asthma multi-morbidity. The European Union Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) has developed a checklist of 28 items for the evaluation of Good Practices. SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. A short summary was proposed for each item and 18 experts, all~members of ARIA and SUNFRAIL from 12 countries, assessed the 28 items using a Survey Monkey-based questionnaire. A visual analogue scale (VAS) from 0 (strongly disagree) to 100 (strongly agree) was used. Agreement equal or over 75% was observed for 14 items (50%). MASK is following the JA-CHRODIS recommendations for the evaluation of Good Practices.
In: Bousquet , J , Onorato , G L , Bachert , C , Barbolini , M , Bedbrook , A , Bjermer , L , De Sousa , J C , Chavannes , N H , Cruz , A A , De Manuel Keenoy , E , Devillier , P , Fonseca , J , Hun , S , Kostka , T , Hellings , P W , Illario , M , Ivancevich , J C , Larenas-Linnemann , D , Millot-Keurinck , J , Ryan , D , Samolinski , B , Sheikh , A , Yorgancioglu , A , Agache , I , Arnavielhe , S , Bewick , M , Annesi-Maesano , I , Anto , J M , Bergmann , K C , Bindslev-Jensen , C , Bosnic-Anticevich , S , Bouchard , J , Caimmi , D P , Camargos , P , Canonica , G W , Cardona , V , Carriazo , A M , Cingi , C , Colgan , E , Custovic , A , Dahl , R , Demoly , P , De Vries , G , Fokkens , W J , Fontaine , J F , Gemicioǧlu , B , Guldemond , N , Gutter , Z , Haahtela , T , Hellqvist-Dahl , B , Jares , E , Joos , G , Just , J , Khaltaev , N , Keil , T , Klimek , L , Kowalski , M L , Kull , I , Kuna , P , Kvedariene , V , Laune , D , Louis , R , Magnan , A , Malva , J , Mathieu-Dupas , E , Melén , E , Menditto , E , Morais-Almeida , M , Mösges , R , Mullol , J , Murray , R , Neffen , H , O'Hehir , R , Palkonen , S , Papadopoulos , N G , Passalacqua , G , Pépin , J L , Portejoie , F , Price , D , Pugin , B , Raciborski , F , Simons , F E R , Sova , M , Spranger , O , Stellato , C , Todo Bom , A , Tomazic , P V , Triggiani , M , Valero , A , Valovirta , E , Vandenplas , O , Valiulis , A , Van Eerd , M , Ventura , M T , Wickman , M , Young , I , Zuberbier , T , Zurkuhlen , A & Senn , A 2017 , ' CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis : A SUNFRAIL report ' , Clinical and Translational Allergy , vol. 7 , no. 1 , 37 . https://doi.org/10.1186/s13601-017-0173-8
A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example of a Good Practice focusing on the implementation of multi-sectoral care pathways using emerging technologies with real life data in rhinitis and asthma multi-morbidity. The European Union Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) has developed a checklist of 28 items for the evaluation of Good Practices. SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. A short summary was proposed for each item and 18 experts, all members of ARIA and SUNFRAIL from 12 countries, assessed the 28 items using a Survey Monkey-based questionnaire. A visual analogue scale (VAS) from 0 (strongly disagree) to 100 (strongly agree) was used. Agreement equal or over 75% was observed for 14 items (50%). MASK is following the JA-CHRODIS recommendations for the evaluation of Good Practices.
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing.
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Sante). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing. ; European Innovation Partnership on Active and Healthy Ageing Reference Site MACVIA-France, European Structural and Development Funds of Region Languedoc Roussillon ; Imperial Coll London, Natl Heart & Lung Inst, Royal Brompton Hosp NHS, London, England ; UPMC Paris 06, Sorbonne Univ,Dept Pneumol & Addictol,UMR S 1136, Hop Arnaud de Villeneuve,CHRU Montpellier, IPLESP,Equipe EPAR,Unite Allergol, F-75013 Paris, France ; Univ S Florida, Morsani Coll Med, Tampa, FL USA ; Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Christine Kuhne Ctr Allergy Res & Educ CK CARE, Davos, Switzerland ; Univ Hosp Ghent, ENT Dept, Upper Airways Res Lab URL, Ghent, Belgium ; IQ4U Consultants Ltd, London, England ; Osped Riuniti, Univ Hosp, Allergy Unit, Dept Internal Med, Ancona, Italy ; Med Univ Vienna, Dept Pathophysiol & Allergy Res, Ctr Pathophysiol Infectiol & Immunol, Vienna, Austria ; Univ Naples 2, Rome, Italy ; CNR, IFT, Rome, Italy ; Univ Genoa, Allergy & Resp Dis Clin, DIMI, IRCCS AOU San Martino IST, Genoa, Italy ; Hosp Univ Vall dHebron, Allergy Sect, Dept Internal Med, Barcelona, Spain ; Montpellier UPMC Univ Paris 06, Sorbonne Univ,UMRS 1136, Hop Arnaud de Villeneuve,Equipe EPAR IPLESP, Div Allergy,Dept Pulmonol,Univ Hosp Montpellier, Paris, France ; Nova Southeastern Univ, Ft Lauderdale, FL USA ; Univ Hosp Strasbourg, Div Allergy, Chest Dis Dept, Strasbourg, France ; Univ Versailles St Quentin, Suresnes, France ; Foch Hosp, Dept Airway Dis, Clin Pharmacol Unit, UPRES EA 220, Suresnes, France ; Rangueil Larrey Hosp, Dept Resp Dis, Toulouse, France ; Univ Palermo, Di Bi MIS, Palermo, Italy ; Kings Coll London, Guys & St Thomas NHS Trust, London, England ; Imperial Coll London, Natl Heart & Lung Inst, Allergy & Clin Immunol Sect, London, England ; Childrens Hosp, Dept Pediat Pulmonol & Allergy, Aarau, Switzerland ; Bambino Gesu Pediat Hosp, Dept Pediat, Div Allergy, Rome, Italy ; Kings Coll London, Allergy Acad, London, England ; Erasmus MC, Dept Internal Med, Bldg Rochussenstr, Rotterdam, Netherlands ; Hosp San Bernardo, Unidad Alergia & Asma, Salta, Argentina ; Helsinki Univ Hosp, Skin & Allergy Hosp, Helsinki, Finland ; Odense Univ Hosp, Hans Christian Andersen Childrens Hosp, Odense, Denmark ; Katholieke Univ Leuven, Univ Hosp Leuven, Clin Dept Otorhinolaryngol Head & Neck Surg, Louvain, Belgium ; Secretary Immunotherapy Interest Grp EAACI, Allergy Learning & Consulting, Copenhagen, Denmark ; UPMC Univ Paris, Sorbonne Univ,Hop Enfants Armand Trousseau,INSERM, Inst Pierre Louis Epidemiol & Sante Publ,Equipe E, Allergol Dept,Ctr Asthme & Allergies,UMR S 1136, Paris, France ; Hosp Sirio Libanes, Sao Paulo, Brazil ; Univ Hosp Montpellier, Montpellier, France ; UPMC Paris 06, Sorbonne Univ, Equipe EPAR, UMR S 1136,IPLESP, Paris, France ; Ackermann Hanf & Kleine Tebbe, Outpatient Clin & Clin Res Ctr, Allergy & Asthma Ctr Westend, Berlin, Germany ; German Soc Otorhinolaryngol HNS, Ctr Rhinol & Allergol, Wiesbaden, Germany ; Univ Med Ctr Utrecht, Dept Immunol & Dermatol Allergol, Utrecht, Netherlands ; Med Univ Lodz, Lodz, Poland ; ARIA, Mexico City, DF, Mexico ; Hosp Med Sur, AAAAI, Mexico City, DF, Mexico ; Capital Reg Denmark, Res Ctr Prevent & Hlth, Copenhagen, Denmark ; Rigshosp, Dept Clin Expt Res, Copenhagen, Denmark ; Univ Copenhagen, Fac Hlth & Med Sci, Dept Clin Med, Copenhagen, Denmark ; Charite Med Univ, Pediat Pneumol & Immunol, Berlin, Germany ; Gentofte Univ Hosp, Allergy Clin, Danish Allergy Ctr, Hellerup, Denmark ; Klinikum Univ Koln AoR, IMSIE, Cologne, Germany ; Hosp Clin Barcelona, Unitat Rinol & Clin Olfacte, ENT Dept, Clin & Expt Resp Immunoallergy,IDIBAPS,CIBERES, Barcelona, Catalonia, Spain ; Padua Gen Univ Hosp, Dept Women & Child Hlth, Food Allergy Referral Ctr Veneto Reg, Padua, Italy ; Univ Athens, Allergy Unit, Pediat Clin 2, Athens, Greece ; Univ Genoa, Allergy & Resp Dis, IRCCS San Martino IST, Genoa, Italy ; ASST Grande Osped Metropolitano Niguarda, Pzza Osped Maggiore, Milan, Italy ; Univ Med Mannheim, Dept Otorhinolaryngol Head & Neck Surg, Mannheim, Germany ; Heidelberg Univ, Med Fac Mannheim, Heidelberg, Germany ; Ctr Rhinol & Allergol, Wiesbaden, Germany ; Univ Aberdeen, Acad Primary Care, Div Appl Hlth Sci, Primary Care Resp Med, Aberdeen, Scotland ; RiRL, Cambridge, England ; Optimum Patient Care Ltd, Singapore, Singapore ; Hosp Infantil Univ Nino Jesus, Allergy Sect, Madrid, Spain ; Ludwig Maximillian Univ, Dept Dermatol & Allergol, Munich, Germany ; Med Univ Warsaw, Dept Prevent Environm Hazards & Allergol, Warsaw, Poland ; Royal Natl Throat Nose & Ear Hosp, London, England ; UCL, London, England ; Univ Zurich Hosp, Clin Trials Ctr, Zurich, Switzerland ; Imperial Coll London, Natl Heart & Lung Inst, Allergy & Clin Immunol Inflammat Repair & Dev Sec, Immunomodulat & Tolerance Grp,Fac Med, London, England ; MRC, London, England ; Asthma UK Ctr Allerg Mechanisms Asthma, London, England ; Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Asthma UK Ctr Appl Res, Med Informat Ctr, Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland ; SLAAI, Asuncion, Paraguay ; Univ Fed Sao Paulo, Programa Posgrad Pediat & Ciencias Aplicadas Pedi, Dept Pediat EPM, Sao Paulo, Brazil ; Med Univ Graz, Dept Dermatol & Venerol, Graz, Austria ; Allergy Outpatient Clin Reumannplatz, Vienna, Austria ; Complejo Hosp Navarra, Serv Alergol, Pamplona, Spain ; Univ Amsterdam, Acad Med Ctr, Dept Expt Immunol, Amsterdam, Netherlands ; Univ Amsterdam, Acad Med Ctr, Dept Otorhinolaryngol, Amsterdam, Netherlands ; Univ Bari, Sch Med, Unit Geriatr Immunoallergol, Interdisciplinary Dept Med, Bari, Italy ; Complejo Hosp Univ Santiago de Compostela, Dept Allergy, Santiago De Compostela, Spain ; Med Univ Graz, Dept Paediat, Resp & Allerg Dis Div, Graz, Austria ; Charite Univ Med Berlin, Klin Dermatol Venerol & Allergol, Allergie Ctr Charite, Berlin, Germany ; European Innovat Partnership Act & Hlth Ageing Re, MAlad Chron Vleillissement Actif Languedoc Roussi, Paris, France ; INSERM, VIMA, Epidemiol & Publ Hlth Approaches, U1168,Ageing & Chron Dis, Paris, France ; Univ Versailles St Quentin En Yvelines, UVSQ, UMR S 1168, Versailles, France ; CHRU, 371 Ave Doyen Gaston Giraud, F-34295 Montpellier 5, France ; Programa de Pòs‑Graduação em Pediatria e Ciências Aplicadas à Pediatria, Departamento de Pediatria EPM, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil ; Web of Science
In: Calderon , M A , Demoly , P , Casale , T , Akdis , C A , Bachert , C , Bewick , M , Bilò , B M , Bohle , B , Bonini , S , Bush , A , Caimmi , D P , Canonica , G W , Cardona , V , Chiriac , A M , Cox , L , Custovic , A , De Blay , F , Devillier , P , Didier , A , Di Lorenzo , G , Du Toit , G , Durham , S R , Eng , P , Fiocchi , A , Fox , A T , van Wijk , R G , Gomez , R M , Haathela , T , Halken , S , Hellings , P W , Jacobsen , L , Just , J , Tanno , L K , Kleine-Tebbe , J , Klimek , L , Knol , E F , Kuna , P , Larenas-Linnemann , D E , Linneberg , A , Matricardi , M , Malling , H J , Moesges , R , Mullol , J , Muraro , A , Papadopoulos , N , Passalacqua , G , Pastorello , E , Pfaar , O , Price , D , Del Rio , P R , Ruëff , R , Samolinski , B , Scadding , G K , Senti , G , Shamji , M H , Sheikh , A , Sisul , J C , Sole , D , Sturm , G J , Tabar , A , Van Ree , R , Ventura , M T , Vidal , C , Varga , E M , Worm , M , Zuberbier , T & Bousquet , J 2016 , ' Allergy immunotherapy across the life cycle to promote active and healthy ageing : from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy ageing) and the Global Alliance against Chronic Respiratory Diseases (GARD), a World Health Organization GARD research demonstration project ' , Clinical and Translational Allergy , vol. 6 , 41 . https://doi.org/10.1186/s13601-016-0131-x
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing.
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Sante). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing. ; Peer reviewed
