Suchergebnisse

Colorectal cancer is an important health problem, being the third most frequent cancer pathology both in men and women. Programmes have been developed to decrease CRC incidence and mortality, including primary prevention strategies focusing on population education regarding diet and physical activity and secondary prevention programmes such as screening. Modifiable risk factors are known to be diet, obesity, smoking, alcohol and read meat consumption. Non-modifiable risk factors are age, inflammatory bowel disease, genetic syndromes and family history of colorectal cancer.

Worldwide, adults and childhood obesity are increasing alarmingly, being a major health problem. Obesity is correlated with an increased incidence of various systemic diseases including cancer, heart diseases, and diabetes mellitus type 2. Risk factors for obesity are dysbiosis, genetic, socioeconomic, behavioural and environmental. The gut microbiota has beneficial effects on human health, like host immune system stimulation, being influenced by pH, or nutrient intake. Studies performed on humans and animal models reported differences regarding microbiota at lean and obese individuals. The consumption of probiotics and prebiotics may balance the microbiota with positive effects in obesity. The main aim of this review is to reveal the interaction between dysbiosis and obesity

Bariatric surgery represents one of the most efficient treatments addressing obesity and its associated complications
with an increasing trend. Even if the medical benefits for patients are huge, due to weight loss and despite technical improvements
in bariatric procedures, it is still associated with diverse types of complications. Most of the complications appear due to nutrient
deficiency, as absorption is compromised after surgical anatomy modification. Neurological complications after bariatric surgery
are very diverse with an occurrence within days to years after surgery, most frequently in patients with gastrointestinal or surgical
complications. Any segment of the nervous system can be affected with distinct types of manifestations ranging from peripheral
axonal neuropathy, nerve palsy secondary to compartment syndrome, encephalopathy, and myelopathy, to psychiatric and
demyelinating central nervous system diseases. Identifying patients at risk and systematic screening for nutrient deficiency with
proper supplementation is essential for preventing neurological complications and lifelong sequelae. In this paper, we present
the spectrum of neurological complications reported after bariatric surgery.

"Currently, the educational process must integrate new tools, to keep pace with technological progress. Our paper aims to investigate the extent to which the preferences of medical students for the autonomous use of multimedia resources in the learning process are correlated with their opinions towards the Internet and the intensity of using it in their daily activities. Methods: We investigated 395 medical students from 4 medical universities in Romania, 75.9% females, and 88.8% in the 1st and 2nd years of study. Students were asked to express on Likert-scales their agreement with a list of statements about Internet services, as well as whether they like learning using multimedia tools and how intensively they use Internet services. Results: The students agree to a medium to large extent with the favorable statements about Internet services but are also aware of the negative influences that indiscriminate use of such technology can have. The intensity of Internet usage is high, although not exaggerated. With small exceptions, the students who enjoy using multimedia resources during the learning process have also favorable opinions about Internet services, and use them constantly, mainly for information and instant messaging on social networks."

" Retinal migraine (ophthalmic migraine, ocular migraine, anterior visual pathway migraine) is a rarely encountered medical condition, but with an interesting and complex clinical presentation. The goal of this article is to compile the literature on retinal migraine, detailing nomenclature, pathophysiology, differential diagnosis, and medical investigations including newer imaging modalities, like optical coherence tomography (OCT). We will approach topics of great concern such as risk factors, complications, treatment, and management of this condition. Retinal migraine is mainly a diagnosis of exclusion and it must be isolated from transient monocular vision loss (TMVL) developed from other causes, for instance, papilledema, giant cell arteritis, carotid artery disease (amaurosis fugax), intermittent angle closure glaucoma, and others. Its treatment is similar to migraine treatment; topiramate, amitriptyline, and nortriptyline are some of the pharmacological drugs successfully used."

"The cytogenetic aberrations induced by doxorubicin (DOX) may be influenced by diet. Investigation regarding effects of low doses of DOX on chromosomal aberrations frequency in mice bone marrow. The study explored a possible relationship between diet, follow-up period, and cytostatic doses. Four mice groups received normal or high-fat (pork) diet. At the beginning of the 8th day mice from each group received a single intraperitoneal injection with DOX (dose range: 1.7-7.7 mg/kg b.w.) or isotonic saline solution (0.02 mL/g control mice). In the 10th (groups I, II) and 14th (groups III, IV) days from the beginning of the experiment, the mice were euthanized and chromosome aberrations were tested in bone marrow cells. The body weight of all mice who received DOX decreases, especially at higher doses. In the first three days post-injection, weight loss percentage was significantly influenced by DOX doses and/or type of diet (p<0.003). The interaction between the type of diet and DOX doses was not statistically significant in the follow-up period (p interactions >0.05). DOX doses were able to increase the frequency of chromosomal aberrations. DOX acts as a potent inductor of cytogenetic aberrations in bone marrow cells, regardless of the type of diet."

20.7.2016 Medicines play a key role in improving the health of patients in Ireland. Securing timely access to medicines for patients at an affordable price, in particular innovative medicines offering enhanced health outcomes, is a key priority for Ireland. Securing the cost effective and economic provision of medicines to the health services in Ireland is vital to free up resources for continued investment in new and innovative medicines for patients; this Agreement is a key element in delivering that objective. This will ensure that Ireland remains at the forefront of its European peers in terms of early access to these new medicines in an affordable manner and within available resources. Framework Agreement on the Supply and Pricing of Medicines

"RPI 502"--P. [4] of cover. ; "January 1997"--P. [4] of cover. ; Shipping list no.: 97-0174-P. ; Cover title. ; Mode of access: Internet. ; 2

"RPI 502"--P. [4] of cover. ; "July 1996"--P. [4] of cover. ; Cover title. ; Mode of access: Internet. ; 2