Decreasing and stabilising trends of antimicrobial consumption and resistance in Escherichia coli and Klebsiella pneumoniae in segmented regression analysis, European Union/European Economic Area, 2001 to 2018
Investments to reduce the spread of antimicrobial resistance (AMR) in the European Union have been made, including efforts to strengthen prudent antimicrobial use. Using segmented regression, we report decreasing and stabilising trends in data reported to the European Surveillance of Antimicrobial Consumption Network and stabilising trends in data reported to the European Antimicrobial Resistance Surveillance Network. Our results could be an early indication of the effect of prioritising AMR on the public health agenda. ; Germán Peñalva was supported by El Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica 2013–2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Economía, Industria y Competitividad, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0001) - co-financed by European Development Regional Fund "A way to achieve Europe", Operative program Intelligent Growth 2014–2020, and received a grant from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for a three-month study visit at ECDC during which the analysis was performed.