Suchergebnisse

Nazeer Hussain Khan,1,2 Shao-Feng Duan,3 Dong-Dong Wu,1,4 Xin-Ying Ji1,4,5 1Henan International Joint Laboratory for Nuclear Protein Regulation, Henan University, Kaifeng, Henan, 475004, People's Republic of China; 2School of Life Sciences, Henan University, Kaifeng, Henan, 475004, People's Republic of China; 3Institute for Innovative Drug Design and Evaluation, School of Pharmacy, Henan University, Kaifeng, Henan, 475004, People's Republic of China; 4School of Basic Medical Sciences, Henan University College of Medicine, Kaifeng, Henan, 475004, People's Republic of China; 5Kaifeng Key Laboratory of Infection and Biological Safety, Henan University College of Medicine, Kaifeng, Henan, 475004, People's Republic of ChinaCorrespondence: Dong-Dong Wu; Xin-Ying Ji Email ddwubiomed2010@163.com; 10190096@vip.henu.edu.cnAbstract: Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women globally. In 2018, 2.1 million new cases were reported, with 627,000 deaths. Pakistan has the highest incidence rate of breast cancer among Asian countries: one in every nine women has a lifetime risk of being diagnosed with breast cancer. By reason of many misconceptions about the etiology of the disease and socioeconomic factors, Pakistani women have very low rates of early detection and diagnose breast cancer at advance stages with fewer chances of survival. The key to cure the breast cancer is early diagnosis. The aim of current review is to highlight the factors leading to the delays in early presentation of breast cancer in Pakistani women and to summarize possible recommendations for educating women about early diagnosis along with palliative care facilities for patients suffering from breast cancer. Furthermore, this study appeals to both the general public and government in the belief that better reporting and awareness campaigns may bring more women to clinics for early diagnosis.Keywords: breast cancer, health budget, Pakistani women, better reporting; awareness campaigns

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women globally. In 2018, 2.1 million new cases were reported, with 627,000 deaths. Pakistan has the highest incidence rate of breast cancer among Asian countries: one in every nine women has a lifetime risk of being diagnosed with breast cancer. By reason of many misconceptions about the etiology of the disease and socioeconomic factors, Pakistani women have very low rates of early detection and diagnose breast cancer at advance stages with fewer chances of survival. The key to cure the breast cancer is early diagnosis. The aim of current review is to highlight the factors leading to the delays in early presentation of breast cancer in Pakistani women and to summarize possible recommendations for educating women about early diagnosis along with palliative care facilities for patients suffering from breast cancer. Furthermore, this study appeals to both the general public and government in the belief that better reporting and awareness campaigns may bring more women to clinics for early diagnosis.

University of Nottingham ; Biotechnology and Biological Sciences Research Council, United Kingdom ; Department for International Development, United Kingdom ; Scottish Government ; Bill & Melinda Gates Foundation ; King Saud University ; King Abdulaziz City for Science and Technology ; Peer Review

To look superior and acceptable in society, people from all over the world use various types of cosmetic products to enhance or alter their facial appearance and body texture. In recent times, an exponential surge in cosmetic use has been observed in Pakistan, and hence spending money on personal-care products is high. However, there are many reported facts about high loads of lead, mercury, copper, and others hazardous and cancerous elements in local Pakistani cosmetic brands. Consumers of these brands are at high risk of many clinical issues, including cancer. As such, it is a necessity to make people aware of the devastating harmful effects related to cosmetic use. The aim of this study was to provide information for stakeholders and raise awareness in the general public about the use of these local unauthorized personal-care cosmetic products, along with government strategies to stop this cosmetic blight on human health.

Nazeer Hussain Khan,1,2 Faiz Ullah,3 Taskin Aman Khan,4 Ujala Zafar,5 Muhammad Farhan Ali Khan,6 Muhammad Mustaqeem,7 Syed Sakhawat Shah,3 Dong-Dong Wu,1,8 Xin-Ying Ji1 1Henan International Joint Laboratory for Nuclear Protein Regulation, Henan University, Henan 475001, People's Republic of China; 2School of Life Sciences, Henan University, Kaifeng, Henan, 475004, People's Republic of China; 3Department of Chemistry, Quaid-I-Azam University, Islamabad 44000, Pakistan; 4Department of Chemistry, University of Sargodha, Sargodha 40100, Pakistan; 5School of Natural Sciences, National University of Science and Technology, Islamabad, 44000, Pakistan; 6Department of Pharmacy, Quaid-I-Azam University, Islamabad 44000, Pakistan; 7Department of Chemistry, University of Sargodha Sub-Campus, Bhakkar 30000, Pakistan; 8School of Basic Medical Sciences, Henan University College of Medicine, Henan 475001, People's Republic of ChinaCorrespondence: Dong-Dong Wu Email ddwubiomed2010@163.comXin-Ying Ji Email 10190096@vip.henu.edu.cnAbstract: To look superior and acceptable in society, people from all over the world use various types of cosmetic products to enhance or alter their facial appearance and body texture. In recent times, an exponential surge in cosmetic use has been observed in Pakistan, and hence spending money on personal-care products is high. However, there are many reported facts about high loads of lead, mercury, copper, and others hazardous and cancerous elements in local Pakistani cosmetic brands. Consumers of these brands are at high risk of many clinical issues, including cancer. As such, it is a necessity to make people aware of the devastating harmful effects related to cosmetic use. The aim of this study was to provide information for stakeholders and raise awareness in the general public about the use of these local unauthorized personal-care cosmetic products, along with government strategies to stop this cosmetic blight on human health.Keywords: cosmetics, cancer, health issues, mercury, Pakistan

Chinese Academy of Sciences ; National Natural Science Foundation of China ; European Union ; United Nations Environment Programme ; Global Environment Programme ; Peer Review