Due to the stricter government regulations on end-of-life product treatment and the increasing public awareness towards environmental issues, remanufacturing has been a significantly growing industry over the last decades, offering many potential business opportunities. In this paper, we investigate a crucial problem apparent in this industry, the remanufacturing lot-sizing problem with separate setups. We first discuss two reformulations of this problem, and remark an important property with regards to their equivalence. Then, we present a theoretical investigation of a related subproblem, where our analysis indicates that a number of flow cover inequalities are strong for this subproblem under some general conditions. We then investigate the computational effectiveness of the alternative methods discussed for the original problem. Detailed numerical results are insightful for the practitioner, indicating that in particular when the return variability increases or when the remanufacturing setup costs decrease relevant to manufacturing setup costs, the flow covers can be very effective.
International audience ; BACterial Hosts for production of Bioac-tive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production This article is written by the BacHBerry consortium (www. bachberry.eu) and represents the collective effort of all participating institutions. The authors are therefore listed in alphabetical order. Electronic supplementary material The online version of this article (
International audience ; BACterial Hosts for production of Bioac-tive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production This article is written by the BacHBerry consortium (www. bachberry.eu) and represents the collective effort of all participating institutions. The authors are therefore listed in alphabetical order. Electronic supplementary material The online version of this article (
International audience ; BACterial Hosts for production of Bioac-tive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production This article is written by the BacHBerry consortium (www. bachberry.eu) and represents the collective effort of all participating institutions. The authors are therefore listed in alphabetical order. Electronic supplementary material The online version of this article (
International audience ; BACterial Hosts for production of Bioac-tive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production This article is written by the BacHBerry consortium (www. bachberry.eu) and represents the collective effort of all participating institutions. The authors are therefore listed in alphabetical order. Electronic supplementary material The online version of this article (
In: Dudnik , A , Almeida , A F , Andrade , R , Avila , B , Banados , P , Barbay , D , Bassard , J-E , Benkoulouche , M , Bott , M , Braga , A , Breitel , D , Brennan , R , Bulteau , L , Chanforan , C , Costa , I , Costa , R S , Doostmohammadi , M , Faria , N , Feng , C , Fernandes , A , Ferreira , P , Ferro , R , Foito , A , Freitag , S , Garcia , G , Gaspar , P , Godinho-Pereira , J , Hamberger , B , Hartmann , A , Heider , H , Jardim , C , Julien-Laferriere , A , Kallscheuer , N , Kerbe , W , Kuipers , O P , Li , S , Love , N , Marchetti-Spaccamela , A , Marienhagen , J , Martin , C , Mary , A , Mazurek , V , Meinhart , C , Sevillano , D M , Menezes , R , Naesby , M , Norholm , M H H , Okkels , F T , Ottens , M & Solopova , A 2018 , ' BacHBerry : BACterial Hosts for production of Bioactive phenolics from bERRY fruits ' , Phytochemistry reviews , vol. 17 , no. 2 , pp. 291-326 . https://doi.org/10.1007/s11101-017-9532-2 ; ISSN:1568-7767
BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds. Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project.
In: Dudnik , A , Almeida , A F , Andrade , R , Avila , B , Bañados , P , Barbay , D , Bassard , J E , Benkoulouche , M , Bott , M , Braga , A , Breitel , D , Brennan , R , Bulteau , L , Chanforan , C , Costa , I , Costa , R S , Doostmohammadi , M , Faria , N , Feng , C , Fernandes , A , Ferreira , P , Ferro , R , Foito , A , Freitag , S , Garcia , G , Gaspar , P , Godinho-Pereira , J , Hamberger , B , Hartmann , A , Heider , H , Jardim , C , Julien-Laferriere , A , Kallscheuer , N , Kerbe , W , Kuipers , O P , Li , S , Love , N , Marchetti-Spaccamela , A , Marienhagen , J , Martin , C , Mary , A , Mazurek , V , Meinhart , C , Sevillano , D M , Menezes , R , Naesby , M , Nørholm , M H H , Okkels , F T , Oliveira , J , Ottens , M , Parrot , D , Pei , L , Rocha , I , Rosado-Ramos , R , Rousseau , C , Sagot , M F , dos Santos , C N , Schmidt , M , Shelenga , T , Shepherd , L , Silva , A R , da Silva , M H , Simon , O , Stahlhut , S G , Solopova , A , Sorokin , A , Stewart , D , Stougie , L , Su , S , Thole , V , Tikhonova , O , Trick , M , Vain , P , Veríssimo , A , Vila-Santa , A , Vinga , S , Vogt , M , Wang , L , Wang , L , Wei , W , Youssef , S , Neves , A R & Forster , J 2018 , ' BacHBerry : BACterial Hosts for production of Bioactive phenolics from bERRY fruits ' , Phytochemistry Reviews , vol. 17 , no. 2 , pp. 291-326 . https://doi.org/10.1007/s11101-017-9532-2
BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds. Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project.
BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds. Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project.