Suchergebnisse

Supported by the Health and Social Care Public Health Agency, Northern Ireland (STL/5268/16 to C.H. and J.G.M.). F.E.-L. received funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant (agreement no. 707404). The funders of the present study did not have any role in the study design, data collection and analyses, decision to publish, or preparation of the manuscript. F.E.-L. is the guarantor of the review. ; Objectives: To determine the effects of exercise on fatigue and sleep quality in fibromyalgia (primary aim) and to identify which type of exercise is the most effective in achieving these outcomes (secondary aim). Data Sources: PubMed and Web of Science were searched from inception until October 18, 2018. Study Selection: Eligible studies contained information on population (fibromyalgia), intervention (exercise), and outcomes (fatigue or sleep). Randomized controlled trials (RCT) testing the effectiveness of exercise compared with usual care and randomized trials (RT) comparing the effectiveness of 2 different exercise interventions were included for the primary and secondary aims of the present review, respectively. Two independent researchers performed the search, screening, and final eligibility of the articles. Of 696 studies identified, 17 RCTs (n=1003) were included for fatigue and 12 RCTs (n=731) for sleep. Furthermore, 21 RTs compared the effectiveness of different exercise interventions (n=1254). Data Extraction: Two independent researchers extracted the key information from each eligible study. Data Synthesis: Separate random-effect meta-analyses were performed to examine the effects from RCTs and from RTs (primary and secondary aims). Standardized mean differences (SMD) effect sizes were calculated using Hedges' adjusted g. Effect sizes of 0.2, 0.4, and 0.8 were considered small, moderate, and large. Compared with usual care, exercise had moderate effects on fatigue and a small effect on sleep quality (SMD, -0.47; 95% confidence interval [CI], -0.67 to -0.27; P<.001 and SMD, -0.17; 95% CI, -0.32 to -0.01; P=.04). RTs in which fatigue was the primary outcome were the most beneficial for lowering fatigue. Additionally, meditative exercise programs were the most effective for improving sleep quality. Conclusions: Exercise is moderately effective for lowering fatigue and has small effects on enhancing sleep quality in fibromyalgia. Meditative exercise programs may be considered for improving sleep quality in fibromyalgia. ; Health and Social Care Public Health Agency, Northern Ireland STL/5268/16 ; European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant 707404

Background: Fibromyalgia is a syndrome characterized by the presence of widespread chronic pain. People with fibromyalgia report lower levels of Positive Affect and higher levels of Negative Affect than non-fibromyalgia peers. The Positive and Negative Affect Schedule (PANAS)–a widely used questionnaire to assess two core domains of affect; namely 'Positive Affect' and 'Negative Affect' –has a controversial factor structure varying across studies. The internal structure of a measurement instrument has an impact on the meaning and validity of its score. Therefore, the aim of the present study was to assess the structural construct validity of the PANAS in adult women with fibromyalgia. Methods: This population-based cross-sectional study included 442 adult women with fibromyalgia (age: 51.3 ± 7.4 years old) from Andalusia (Southern Spain). Confirmatory factor analyses were conducted to test the factor structure of the PANAS. Results: A structure with two correlated factors (Positive Affect and Negative Affect) obtained the best fit; S-B χ2 = 288.49, df = 155, p < .001; RMSEA = .04; 90% CI of RMSEA = (.036, .052); the best fit SRMR = .05; CFI = .96; CAIC = −810.66, respectively. Conclusions: The present study demonstrates that both Positive Affect and Negative Affect are core dimensions of affect in adult women with fibromyalgia. A structure with two correlated factors of the PANAS emerged from our sample of women with fibromyalgia from Andalusia (Southern Spain). In this model, the amount of variance shared by Positive Affect and Negative Affect was small. Therefore, our findings support to use and interpret the Positive Affect and Negative Affect subscales of the PANAS as separate factors that are associated but distinctive as well. ; This study was funded by the Spanish Ministry of Economy and Competitiveness [I+D+i DEP2010-15639 and I+D+i DEP2013-40908-R], the Consejeria de Turismo, Comercio y Deporte (CTCD-201000019242-TRA), the Andalusia Institute of Sport, the Center of Initiatives and Cooperation to the Development (CICODE, University of Granada), and the Andalusian Federation of people with fibromyalgia, chronic fatigue, and multiple, chemical sensitivity (Alba Andalucı ́ a). FE-L [Grant number: BES-2014-067612] and ICA-G [Grant number: BES-2011-047133] were supported by Grants from the Spanish Ministry of Economy and Competitiveness. VAA was supported by the Andalucı ́ a Talent Hub Program launched by the Andalusian Knowledge Agency, co-funded by the European Union's Seventh Framework Program, Marie Sk 1 odowska-Curie actions (COFUND–Grant Agreement no 291780) and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucı ́ a. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. ; This study was funded by the Spanish Ministry of Economy and Competitiveness [I+D+i DEP2010-15639 and I+D+i DEP2013-40908-R], the Consejeria de Turismo, Comercio y Deporte (CTCD-201000019242-TRA), the Andalusia Institute of Sport, the Center of Initiatives and Cooperation to the Development (CICODE, University of Granada), and the Andalusian Federation of people with fibromyalgia, chronic fatigue, and multiple, chemical sensitivity (Alba Andalucia). FE-L [Grant number: BES-2014-067612] and ICA-G [Grant number: BES-2011-047133] were supported by Grants from the Spanish Ministry of Economy and Competitiveness. VAA was supported by the Andalucia Talent Hub Program launched by the Andalusian Knowledge Agency, co-funded by the European Union's Seventh Framework Program, Marie Sklodowska-Curie actions (COFUND-Grant Agreement no 291780) and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

To examine the associations of prolonged sedentary time (ST) with disease severity in women with fibromyalgia, and to analyse the combined association of total ST and prolonged ST with the disease severity in this population. Women (n = 451; 51.3 +/- 7.6 years old) with fibromyalgia participated. Sedentary time and moderate-to-vigorous physical activity (MVPA) were measured using triaxial accelerometry and ST was processed into 30- and 60-min bouts. Dimensions of fibromyalgia (function, overall, symptoms) and the overall disease impact were assessed with the Revised Fibromyalgia Impact Questionnaire (FIQR). Body fat percentage was assessed using a bio-impedance analyser, and physical fitness was assessed with the Senior Fitness Tests Battery. Greater percentage of ST in 30-min bouts and 60-min bouts were associated with worse function, overall, symptoms and the overall impact of the disease (all, P 60-min bouts) presented lower overall impact compared to participants with high levels of total ST and prolonged ST (mean difference = 6.56; 95% confidence interval (CI) = 1.83 to 11.29, P = 0.002). Greater percentage of ST accumulated in 30- and 60-min bouts and a combination of high levels of total and prolonged ST are related to worse disease severity. Although unable to conclude on causality, results suggest it might be advisable to motivate women with fibromyalgia to break prolonged ST and reduce their total daily ST. ; This research was funded by the Spanish Ministry of Science and Innovation (I+D+I DEP2010-15639), the Consejería de Turismo, Comercio y Deporte (CTCD-201000019242-TRA), the Spanish Ministry of Education (FPU15/00002), Granada Research of Excelence Initiative on Biohealth (GREIB), Campus BioTic, University of Granada, Spain, the University of Granada (Plan Propio de Investigación 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health [UCEES]), and the University of Cádiz (Research and Transfer Activity Promotion Program). FE-L has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 707404.

Objectives To analyse the association between the type of work (productive vs reproductive work) and the levels of physical activity and sedentary behaviour in women with fibromyalgia. Method This cross-sectional study involved 258 women with fibromyalgia from southern Spain. Of them, 55% performed reproductive work (unpaid, associated with caregiving and domestic roles) exclusively, while 45% had productive job (remunerated, that results in goods or services). Physical activity of light, moderate and vigorous intensity in the leisure time, at home, at work, and totally were measured through the leisure time physical activity instrument and with the physical activity at home and work instrument, respectively. Sedentary behaviour was measured by the Sedentary Behaviour Questionnaire. Results After adjusting for age, fat percentage, education level and marital status, the multivariate analysis of covariance model informed the existence of significant differences between type of work groups (p0.05 for all comparisons). Conclusions Women with productive work had greater levels of physical activity compared with those who only did reproductive work, except for physical activity at home. Having productive work might facilitate movement of women with fibromyalgia towards a more active lifestyle. ; Spanish Ministries of Economy and Competitiveness I+D+i DEP2010-15639 I+D+i DEP2013-40908-R ; Spanish Government FPU15/00002 ; University of Granada, Plan Propio de Investigacion 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES) ; Junta de Andalucia, Consejeria de Conocimiento, Investigacion y Universidades and European Regional Development Fund (ERDF) SOMM17/6107/UGR ; European Union (EU) 707404

Positive psychology is the study of positive subjective experience and individual traits. Identifying deficits in positive psychology regarding fibromyalgia may inform targets for management. Therefore, the aim of the present case-control study was to compare the levels of positive affect, negative affect, satisfaction with life, optimism and emotional repair in a large sample of women with fibromyalgia (cases) and age-matched peers without fibromyalgia (controls). This case-control study included 437 women with fibromyalgia (51.6 & PLUSMN; 7.1 years old) and 206 age-matched women without fibromyalgia (50.6 & PLUSMN; 7.2 years old). Participants self-reported their levels of (i) subjective well-being on the Positive and Negative Affect Schedule and the Satisfaction with Life Scale, (ii) dispositional optimism on the Life Orientation Test-Revised and (iii) emotional repair on the Trait Meta-Mood Scale. Women with fibromyalgia showed lower levels of positive affect, satisfaction with life, optimism and emotional repair and higher levels of negative affect. Large effect sizes were found for positive affect, negative affect and satisfaction with life (all, Cohen's d & GE; 0.80) and small-to-moderate for emotional repair and optimism (both, Cohen's d & GE; 0.50). Women with fibromyalgia experience deficits of positive psychology resources. Thus, developing tailored therapies for fibromyalgia focusing on reducing deficits in positive psychology resources may be of clinical interest, though this remains to be corroborated in future research. ; This work was supported by the Spanish Ministry of Economy and Competitiveness (I+D+i DEP2010-15639, I+D+I DEP2013-40908); the Spanish Ministry of Education (FPU15/00002), Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES). F.E.-L. has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 707404. The funders of this study did not have any role in the study design, data collection and analyses, decision to publish or preparation of the manuscript.

Positive psychology is the study of positive subjective experience and individual traits. Identifying deficits in positive psychology regarding fibromyalgia may inform targets for management. Therefore, the aim of the present case–control study was to compare the levels of positive affect, negative affect, satisfaction with life, optimism and emotional repair in a large sample of women with fibromyalgia (cases) and age-matched peers without fibromyalgia (controls). This case–control study included 437 women with fibromyalgia (51.6 ± 7.1 years old) and 206 age-matched women without fibromyalgia (50.6 ± 7.2 years old). Participants self-reported their levels of (i) subjective well-being on the Positive and Negative Affect Schedule and the Satisfaction with Life Scale, (ii) dispositional optimism on the Life Orientation Test-Revised and (iii) emotional repair on the Trait Meta-Mood Scale. Women with fibromyalgia showed lower levels of positive affect, satisfaction with life, optimism and emotional repair and higher levels of negative affect. Large effect sizes were found for positive affect, negative affect and satisfaction with life (all, Cohen's d ≥ 0.80) and small-to-moderate for emotional repair and optimism (both, Cohen's d ≥ 0.50). Women with fibromyalgia experience deficits of positive psychology resources. Thus, developing tailored therapies for fibromyalgia focusing on reducing deficits in positive psychology resources may be of clinical interest, though this remains to be corroborated in future research ; This work was supported by the Spanish Ministry of Economy and Competitiveness (I+D+i DEP2010-15639, I+D+I DEP2013-40908); the Spanish Ministry of Education (FPU15/00002), Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES). F.E.-L. has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 707404. The funders of this study did not have any role in the study design, data collection and analyses, decision to publish or preparation of the manuscript We would like to thank the researchers of the cts-1018 research group, particularly Manuel Delgado-Fernández, and acknowledge the "Fibromyalgia, Chronic Fatigue Syndrome and Chemistry Sensibility Federation" ("ALBA ANDALUCIA", association of fibromyalgia, Andalucía, southern Spain

Background: Fibromyalgia is a syndrome characterized by the presence of widespread chronic pain. People with fibromyalgia report lower levels of Positive Affect and higher levels of Negative Affect than non-fibromyalgia peers. The Positive and Negative Affect Schedule (PANAS)–a widely used questionnaire to assess two core domains of affect; namely 'Positive Affect' and 'Negative Affect' –has a controversial factor structure varying across studies. The internal structure of a measurement instrument has an impact on the meaning and validity of its score. Therefore, the aim of the present study was to assess the structural construct validity of the PANAS in adult women with fibromyalgia. ; Methods: This population-based cross-sectional study included 442 adult women with fibromyalgia (age: 51.3 ± 7.4 years old) from Andalusia (Southern Spain). Confirmatory factor analyses were conducted to test the factor structure of the PANAS. ; Results: A structure with two correlated factors (Positive Affect and Negative Affect) obtained the best fit; S-B χ2 = 288.49, df = 155, p < .001; RMSEA = .04; 90% CI of RMSEA = (.036, .052); the best fit SRMR = .05; CFI = .96; CAIC = −810.66, respectively. ; Conclusions: The present study demonstrates that both Positive Affect and Negative Affect are core dimensions of affect in adult women with fibromyalgia. A structure with two correlated factors of the PANAS emerged from our sample of women with fibromyalgia from Andalusia (Southern Spain). In this model, the amount of variance shared by Positive Affect and Negative Affect was small. Therefore, our findings support to use and interpret the Positive Affect and Negative Affect subscales of the PANAS as separate factors that are associated but distinctive as well. ; This study was funded by the Spanish Ministry of Economy and Competitiveness [I+D+i DEP2010-15639 and I+D+i DEP2013-40908-R], the Consejeria de Turismo, Comercio y Deporte (CTCD-201000019242-TRA), the Andalusia Institute of Sport, the Center of Initiatives and Cooperation to the Development (CICODE, University of Granada), and the Andalusian Federation of people with fibromyalgia, chronic fatigue, and multiple, chemical sensitivity (Alba Andalucía). FE-L [Grant number: BES-2014-067612] and ICA-G [Grant number: BES-2011-047133] were supported by Grants from the Spanish Ministry of Economy and Competitiveness. VAA was supported by the Andalucía Talent Hub Program launched by the Andalusian Knowledge Agency, co-funded by the European Union's Seventh Framework Program, Marie Skodowska-Curie actions (COFUND–Grant Agreement no 291780) and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucía.

[Background] The high prevalence of women that do not reach the recommended level of physical activity is worrisome. A sedentary lifestyle has negative consequences on health status and increases health care costs. The main objective of this project is to assess the cost-effectiveness of a primary care-based exercise intervention in perimenopausal women. ; [Methods/Design] The present study is a Randomized Controlled Trial. A total of 150 eligible women will be recruited and randomly assigned to either a 16-week exercise intervention (3 sessions/week), or to usual care (control) group. The primary outcome measure is the incremental cost-effectiveness ratio. The secondary outcome measures are: i) socio-demographic and clinical information; ii) body composition; iii) dietary patterns; iv) glycaemic and lipid profile; v) physical fitness; vi) physical activity and sedentary behaviour; vii) sleep quality; viii) quality of life, mental health and positive health; ix) menopause symptoms. All outcomes will be assessed at baseline and post intervention. The data will be analysed on an intention-to-treat basis and per protocol. In addition, we will conduct a cost effectiveness analysis from a health system perspective. ; [Discussion] The intervention designed is feasible and if it proves to be clinically and cost effective, it can be easily transferred to other similar contexts. Consequently, the findings of this project might help the Health Systems to identify strategies for primary prevention and health promotion as well as to reduce health care requirements and costs. ; This study was supported by the project: "Cost effectiveness of an exercise intervention program in perimenopausal women". Reference: PI-0667-2013 and funded by the Ministry of Health of the Junta de Andalucía. AS-M (grant number: FPU12/00963) and VS-J (grant number: AP2010-0963) were supported by the Spanish Ministry of Education. ICA-G (grant number: BES-2011-047133) and FE-L (grant number: BES-2014-067612) were supported by the Ministry of Economy and Competitiveness. VAA was also supported by the Andalucía Talent Hub Program launched by the Andalusian Knowledge Agency, co-funded by the European Union's Seventh Framework Program, Marie Skłodowska-Curie actions (COFUND – Grant Agreement n° 291780) and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucía.

Designed by a group of ME/CFS researchers and health professionals, the European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE) has received funding from the European Cooperation in Science and Technology (COST)-COST action 15111-from 2016 to 2020. The main goal of the Cost Action was to assess the existing knowledge and experience on health care delivery for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in European countries, and to enhance coordinated research and health care provision in this field. We report our findings and make recommendations for clinical diagnosis, health services and care for people with ME/CFS in Europe, as prepared by the group of clinicians and researchers from 22 countries and 55 European health professionals and researchers, who have been informed by people with ME/CFS.