One More Case for Longer-Term Mortgages: Financial Stability
In: C.D. Howe Institute e-Brief 299
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In: C.D. Howe Institute e-Brief 299
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Working paper
In: Stanford Public Law Working Paper No. 2811773
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Working paper
In: The Journal of social psychology, Volume 112, Issue 1, p. 91-97
ISSN: 1940-1183
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Wilson, C. A., Feldman, M. G., Carron, M. J., Dannreuther, N. M., Farrington, J. W., Halanych, K. M., Petitt, J. L., Rullkotter, J., Sandifer, P. A., Shaw, J. K., Shepherd, J. G., Westerholm, D. G., Yanoff, C. J., & Zimmermann, L. A. Summary of findings and research recommendations from the Gulf of Mexico Research Initiative. Oceanography, 34(1), (2021): 228–239, https://doi.org/10.5670/oceanog.2021.128. ; Following the Deepwater Horizon explosion and oil spill in 2010, the Gulf of Mexico Research Initiative (GoMRI) was established to improve society's ability to understand, respond to, and mitigate the impacts of petroleum pollution and related stressors of the marine and coastal ecosystems. This article provides a high-level overview of the major outcomes of the scientific work undertaken by GoMRI. This i scientifically independent initiative, consisting of over 4,500 experts in academia, government, and industry, contributed to significant knowledge advances across the physical, chemical, geological, and biological oceanographic research fields, as well as in related technology, socioeconomics, human health, and oil spill response measures. For each of these fields, this paper outlines key advances and discoveries made by GoMRI-funded scientists (along with a few surprises), synthesizing their efforts in order to highlight lessons learned, future research needs, remaining gaps, and suggestions for the next generation of scientists.
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In: Springer eBook Collection
Official Opening, Monday, June 28, 1971 -- Chairman: Albert B. Sabin -- Speakers: Théo Lefèvre -- Altiero Spinelli -- Morning Session, Monday, June 28, 1971 -- Chairman: John C. Kendrew -- Speakers: Friedrich Cramer "Can our Society meet the -- Challenge of a Technological Future?" -- Aharon Katzir-Katchalsky "A Scientist's Approach to Human Values" -- Discussion -- Afternoon Session, Monday, June 28, 1971 -- Chairman: Hendrik B. G. Casimir -- Speakers: Léon Van Hove "Physical Science in Relation to Human Thought and Action" -- Chaim L. Pekeris "The Impact of Physical Sciences on Society" -- Discussion -- Evening, Monday, June 28, 1971 -- Chairman: Siegmund G. Warburg -- Speaker: Raymond Aron "Evening Address" -- Morning Session, Tuesday, June 29, 1971 -- Chairman: Wolfgang Gentner -- Speakers: Ole Maaløe "Can Ideas from Molecular Biology be applied to Economic and Social Systems?" -- David Samuel "Science and the Control of Man's Mind" -- Discussion -- Afternoon Session, Tuesday, June 29, 1971 -- Chairman: Michael J. Higatsberger -- Speakers: Jean-Jacques Salomon "Science and Scientists' Responsibilities in Today's Society" -- Michael Feldman "Science and the Crisis of Democracy" -- Discussion -- Conclusion -- Speakers: Victor F. Weisskopf -- Albert B. Sabin -- Appendix The Weizmann Institute -- Name Index.
In: Marine policy, Volume 131, p. 104554
ISSN: 0308-597X
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale.
BASE
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types.
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